Impact of antibiotics on arterial blood pressure in a patient with resistant hypertension — A case report
Open accessThe claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Interventions that target the gut microbiota, such as a high-fibre diet, probiotics and antibiotics, have blood-pressure lowering effects in animal models and in patients with hypertension.
“Finally, studies in animal models and in patients with hypertension have reported that interventions that target the gut microbiota, such as a high-fibre diet, probiotics and antibiotics, have blood-pressure lowering effects87,92–99.”
From The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease (2018) · cites this paper as [99]
In a patient with treatment-resistant hypertension, antibiotic therapy using vancomycin, rifampin and ciprofloxacin decreased systolic blood pressure by ~70 mmHg in the absence of antihypertensive drugs.
“In a case of patient with treatment-resistant hypertension, antibiotic therapy using a combination of vancomycin, rifampin and ciprofloxacin decreased SBP by ~70 mmHg in the absence of antihypertensive drugs99.”
From The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease (2018) · cites this paper as [99]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Gut flora in health and disease
Guarner, F., & Malagelada, J. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12489-0 · Cited by 3,395 · see citing works
Dethlefsen, L., & Relman, D. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000087107 · Cited by 2,421 · see citing works
Gut Dysbiosis Is Linked to Hypertension
Yang, T., Santisteban, M. M., Rodriguez, V., Li, E., Ahmari, N., Carvajal, J. M., Zadeh, M., Gong, M., Qi, Y., Zubcevic, J., et al. (2015) · Hypertension · doi:10.1161/hypertensionaha.115.05315 · Cited by 1,478 · see citing works
Self-citationBrain Microglial Cytokines in Neurogenic Hypertension
Shi, P. D., Díez-Freire, C., Jun, J. Y., Qi, Y., Katovich, M. J., Li, Q., Sriramula, S., Francis, J., Sumners, C., & Raizada, M. K. (2010) · Hypertension · doi:10.1161/hypertensionaha.110.150409 · Cited by 384 · see citing works
Self-citationAntibiotic administration alters the community structure of the gastrointestinal microbiota
Robinson, C. J., & Young, V. B. (2010) · Gut Microbes · doi:10.4161/gmic.1.4.12614 · Cited by 161 · see citing works
Immunomodulatory Properties of Antibiotics
Nau, R., & Tauber, S. C. (2008) · Current Molecular Pharmacology · doi:10.2174/1874467210801010068 · Cited by 156 · see citing works
Abarbanel, D. N., Seki, S. M., Davies, Y. K., Marlen, N., Benavides, J. A., Cox, K. M., Nadeau, K. C., & Cox, K. L. (2012) · Journal of Clinical Immunology · doi:10.1007/s10875-012-9801-1 · Cited by 119 · see citing works
A complex microworld in the gut: Gut microbiota and cardiovascular disease connectivity
Howitt, M. R., & Garrett, W. S. (2012) · Nature Medicine · doi:10.1038/nm.2895 · Cited by 77 · see citing works
Bone marrow-CNS connections: Implications in the pathogenesis of diabetic retinopathy
Douglas, J. Y., Bhatwadekar, A. D., Calzi, S. L., Shaw, L. C., Carnegie, D., Caballero, S., Li, Q., Stitt, A. W., Raizada, M. K., & Grant, M. B. (2012) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2012.04.005 · Cited by 55 · see citing works
Self-citationCardiovascular and Renal Complications in Patients with Resistant Hypertension
Muxfeldt, E. S., de Souza, F., Margallo, V. S., & Salles, G. F. (2014) · Current Hypertension Reports · doi:10.1007/s11906-014-0471-7 · Cited by 31 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Gut microbiota dysbiosis contributes to the development of hypertension
Li, J., Zhao, F., Wang, Y., Chen, J., Tao, J., Tian, G., Wu, S., Liu, W., Cui, Q., Geng, B., et al. (2017) · Microbiome · doi:10.1186/s40168-016-0222-x · Cited by 1,685 · see citing works
The gut microbiota and the brain–gut–kidney axis in hypertension and chronic kidney disease
Yang, T., Richards, E. M., Pepine, C. J., & Raizada, M. K. (2018) · Nature Reviews Nephrology · doi:10.1038/s41581-018-0018-2 · Cited by 753 · see citing works
Self-citationThe Gut Microbiome, Energy Homeostasis, and Implications for Hypertension
Riedl, R. A., Atkinson, S. N., Burnett, C. M. L., Grobe, J. L., & Kirby, J. R. (2017) · Current Hypertension Reports · doi:10.1007/s11906-017-0721-6 · Cited by 58 · see citing works
The Role of Microbiota in Cardiovascular Risk: Focus on Trimethylamine Oxide
Al-Rubaye, H., Perfetti, G., & Kaski, J.-C. (2019) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2018.06.005 · Cited by 43 · see citing works
Gut microbiota in common elderly diseases affecting activities of daily living
Shimizu, Y. (2018) · World Journal of Gastroenterology · doi:10.3748/wjg.v24.i42.4750 · Cited by 40 · see citing works
- Authors
- Qi, Y., Aranda, J. M., Rodriguez, V., Raizada, M. K., & Pepine, C. J.
- Affiliations
- University of Florida (US)
- Corresponding author
- Pepine, Carl J.
- Venue
- International Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 2015-12
- Volume
- 201
- Pages
- 157-158
- ISSN
- 0167-5273 (ISSN-L)
- PMC
- PMC4711349
- OpenAlex
- W2163195593
- Cited by
- 79
- References
- 10
- Citations by year
- 2025: 2 · 2024: 5 · 2023: 3 · 2022: 12 · 2021: 18 · 2020: 11 · 2019: 7 · 2018: 8 · 2017: 10 · 2016: 2 · 2015: 1
- FWCI
- 5.09
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- International Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (2 UM1 HL087366-06, R01 HL056921, HL33610, UL1 TR000064)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Renal and Vascular Pathologies
- Keywords
- resistant hypertension, antibiotics, arterial blood pressure, antihypertensive drugs, adverse drug reactions
- MeSH terms
- Aged, Anti-Bacterial Agents, Antihypertensive Agents, Drug Therapy, Combination, Female, Humans, Hypertension, Arterial Pressure
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
