Cited by 145Advancements in Transdermal Drug DeliveryNanoparticle-Based Drug DeliveryAdvanced Drug Delivery Systems

The DOI matches its Crossref record; 28 of the 29 references it cites were found in a registry or an index.

Tretinoin-loaded nanocapsules: Preparation, physicochemical characterization, and photostability study

Ourique, A.F., Pohlmann, A.R., Guterres, S.S., Beck, R.C.R.·2008·International Journal of Pharmaceutics

DOI 10.1016/j.ijpharm.2007.12.035

Open this paper in CoChat — free account

Abstract

The aim of this study was to prepare and characterize tretinoin-loaded nanocapsules as well as to evaluate the influence of this nanoencapsulation on tretinoin photostability. Tretinoin-loaded nanocapsules (0.5 mg ml(-1)) were prepared by interfacial deposition of preformed polymer (poly-epsilon-caprolactone) using two different oily phases: capric/caprylic triglycerides and sunflower seed oil. Tretinoin-loaded nanocapsules presented drug content close to the theoretical value, encapsulation efficiencies higher than 99.9%, nanometric mean size with a polydispersity index below 0.25, and pH values between 5.0 and 7.0. Regarding photodegradation studies, tretinoin methanolic solution showed a half-life time around 40 min according to a first order equation, whereas tretinoin nanocapsule suspensions showed a half-life between 85 and 100 min (twofold higher than in methanolic solution) according to a zero order equation. Tretinoin-loaded nanocapsules improved tretinoin photostability, independently on the type of oily phase used in this study, and represent a potential system to be incorporated in topical or systemic dosage forms containing tretinoin.

Integrity signals

Registry

Crossref · 10.1016/j.ijpharm.2007.12.035

Cites

28 of 28 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Nanocapsule Technology: A Review
Couvreur, P., BARRATT, G. M., Fattal, E., & Vauthier, C. (2002) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.v19.i2.10 · Cited by 556
Polymeric Nanoparticles, Nanospheres and Nanocapsules, for Cutaneous Applications
Guterres, S. S., Alves, M. P., & Pohlmann, A. R. (2007) · Drug Target Insights · doi:10.1177/117739280700200002 · Cited by 462
Self-citation
Caracterização e estabilidade físico-química de sistemas poliméricos nanoparticulados para administração de fármacos
Schaffazick, S. R., Guterres, S. S., Freitas, L. D. L., & Pohlmann, A. R. (2003) · Química Nova · doi:10.1590/s0100-40422003000500017 · Cited by 396
Self-citation
Solid lipid nanoparticles (SLN) of tretinoin: Potential in topical delivery
Shah, K. P., Date, A. A., Joshi, M. D., & Patravale, V. B. (2007) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2007.05.061 · Cited by 359
Polymeric nanoparticles, nanospheres and nanocapsules, for cutaneous applications.
Guterres, S. S., Alves, M. P., & Pohlmann, A. R. (2007) · PubMed · Cited by 302
Self-citation
Gliadin nanoparticles for the controlled release of all-trans-retinoic acid
Ezpeleta, I., Irache, J. M., Stainmesse, S., Chabenat, C., Guéguen, J., Popineau, Y., & Orecchioni, A. M. (1996) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(95)04338-1 · Cited by 201
Effect of nanoparticle encapsulation on the photostability of the sunscreen agent, 2-ethylhexyl-p-methoxycinnamate
Perugini, P., Simeoni, S., Scalia, S., Genta, I., Modena, T., Conti, B., & Pavanetto, F. (2002) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(02)00356-3 · Cited by 164
Niosomes as carriers for tretinoin II. Influence of vesicular incorporation on tretinoin photostability
Manconi, M. (2003) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(03)00268-0 · Cited by 156
Human skin penetration and distribution of nimesulide from hydrophilic gels containing nanocarriers
Alves, M. P., Scarrone, A. L., dos Santos, M. R., Pohlmann, A. R., & Guterres, S. S. (2007) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2007.03.031 · Cited by 149
Self-citation
Influence of encapsulation on the in vitro percutaneous absorption of octyl methoxycinnamate
Jiménez, M. M., Pelletier, J., Bobin, M.-F., & Martini, M. C. (2004) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2003.11.029 · Cited by 143

Show all 29 references

Research works printed but not linked: 1

Polano, 1974, Tretinoin in dermatologie, Pharm. Weekblad., 109, 908

Sorted by citations

Polymer-based nanocapsules for drug delivery
Mora‐Huertas, C. E., Fessi, H., & Elaı̈ssari, A. (2009) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2009.10.018 · Cited by 1,744
New trends in encapsulation of liposoluble vitamins
Gonnet, M., Lethuaut, L., & Boury, F. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.01.037 · Cited by 351
The emerging role of nanotechnology in skincare
Salvioni, L., Morelli, L., Ochoa, E., Labra, M., Fiandra, L., Palugan, L., Prosperi, D., & Colombo, M. (2021) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2021.102437 · Cited by 344
Nanoparticle-Enabled Transdermal Drug Delivery Systems for Enhanced Dose Control and Tissue Targeting
Palmer, B. C., & DeLouise, L. A. (2016) · Molecules · doi:10.3390/molecules21121719 · Cited by 279
Poly(ϵ-caprolactone) microcapsules and nanocapsules in drug delivery
Pohlmann, A. R., da Fonseca, F. N., Paese, K., Detoni, C. B., Coradini, K., Beck, R. C. R., & Guterres, S. S. (2013) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2013.769956 · Cited by 229
Self-citation
Nanotechnology in cosmetics
Katz, L. M. G., Dewan, K., & Bronaugh, R. L. (2015) · Food and Chemical Toxicology · doi:10.1016/j.fct.2015.06.020 · Cited by 196
Non-invasive drug delivery technology: development and current status of transdermal drug delivery devices, techniques and biomedical applications
Akhtar, N., Singh, V., Yusuf, M., & Khan, R. A. (2020) · Biomedizinische Technik/Biomedical Engineering · doi:10.1515/bmt-2019-0019 · Cited by 197
Novel colloidal carriers for psoriasis: Current issues, mechanistic insight and novel delivery approaches
Pradhan, M., Singh, D., & Singh, M. R. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.05.020 · Cited by 195
Chitosan-solid lipid nanoparticles as carriers for topical delivery of tretinoin
Ridolfi, D. M., Marcato, P. D., Justo, G. Z., Cordi, L., Machado, D., & Durán, N. (2011) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2011.11.051 · Cited by 183
Psoriasis: From Pathogenesis to Pharmacological and Nano-Technological-Based Therapeutics
Petit, R. G., Cano, A. C., Ortiz, A., Espina, M., Prat, J., Muñoz-Mateu, M., Severino, P. B., Souto, E. B., García, M. L., Pujol, M., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094983 · Cited by 158
Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine
Ferreira, R., Napoli, J., Enver, T., Bernardino, L., & Ferreira, L. (2020) · Nature Communications · doi:10.1038/s41467-020-18042-2 · Cited by 138
Improved photostability and reduced skin permeation of tretinoin: Development of a semisolid nanomedicine
Ourique, A. F., Melero, A., Silva, C. D. B. D., Schaefer, U. F., Pohlmann, A. R., Guterres, S. S., Lehr, C.-M., Kostka, K.-H., & Beck, R. C. R. (2011) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2011.03.008 · Cited by 132
Self-citation
An integrated buccal delivery system combining chitosan films impregnated with peptide loaded PEG-b-PLA nanoparticles
Giovino, C., Ayensu, I., Tetteh, J., & Boateng, J. S. (2013) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2013.07.019 · Cited by 127
Nanocosmetics and Nanomedicines
(2011) · doi:10.1007/978-3-642-19792-5 · Cited by 116
Self-citation
Nanomedicine-based drug targeting for psoriasis: potentials and emerging trends in nanoscale pharmacotherapy
Rahman, M., Akhter, S., Ahmad, J., Ahmad, M. Z., Beg, S., & Ahmad, F. J. (2014) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2015.982088 · Cited by 113
Monoclonal antibody as a targeting mediator for nanoparticle targeted delivery system for lung cancer
Wathoni, N., Puluhulawa, L. E., Joni, I. M., Muchtaridi, M., Mohammed, A. F. A., Elamin, K. M., Milanda, T., & Gozali, D. (2022) · Drug Delivery · doi:10.1080/10717544.2022.2120566 · Cited by 111
Bacterial-Derived Polymer Poly-y-Glutamic Acid (y-PGA)-Based Micro/Nanoparticles as a Delivery System for Antimicrobials and Other Biomedical Applications
Khalil, I., Burns, A., Radecka, I., Kowalczuk, M. M., Khalaf, T., Adamus, G., Johnston, B., & Khechara, M. P. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18020313 · Cited by 96
Hydrogel containing dexamethasone-loaded nanocapsules for cutaneous administration: preparation, characterization, and in vitro drug release study
Marchiori, M., Lubini, G., Nora, G. D., Friedrich, R. B., Fontana, M. C., Ourique, A. F., Bastos, M. O., Rigo, L. A., da Silva, C. B., Tedesco, S. B., et al. (2010) · Drug Development and Industrial Pharmacy · doi:10.3109/03639041003598960 · Cited by 92
Self-citation
Nanostructured Systems Containing Rutin: In Vitro Antioxidant Activity and Photostability Studies
Almeida, J., Lima, F. O., Ros, S. D., Bulhões, L. O. S., de Carvalho, L. M., & Beck, R. C. R. (2010) · Nanoscale Research Letters · doi:10.1007/s11671-010-9683-1 · Cited by 92
Self-citation
Nanocarriers as Active Ingredients Enhancers in the Cosmetic Industry—The European and North America Regulation Challenges
Oliveira, C., Coelho, C., Teixeira, J. A., Ferreira‐Santos, P., & Botelho, C. (2022) · Molecules · doi:10.3390/molecules27051669 · Cited by 99
Formulation and in vitro evaluation of coconut oil-core cationic nanocapsules intended for vaginal delivery of clotrimazole
Santos, S. S., Lorenzoni, A. S., Pegoraro, N. S., Denardi, L. B., Alves, S. H., Schaffazick, S. R., & Cruz, L. (2014) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2014.01.011 · Cited by 91
Polymeric nanospheres for topical delivery of vitamin D3
Ramezanli, T., Kilfoyle, B. E., Zhang, Z., & Michniak‐Kohn, B. B. (2016) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2016.10.072 · Cited by 88
Photostability and Skin Penetration of Different E‐Resveratrol‐Loaded Supramolecular Structures
Detoni, C. B., Souto, G. D., da Silva, A. L. M., Pohlmann, A. R., & Guterres, S. S. (2012) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2012.01147.x · Cited by 87
Self-citation
Clotrimazole-loaded Eudragit® RS100 nanocapsules: Preparation, characterization and in vitro evaluation of antifungal activity against Candida species
Santos, S. S., Lorenzoni, A. S., Ferreira, L. M., Mattiazzi, J., Adams, A. I. H., Denardi, L. B., Alves, S. H., Schaffazick, S. R., & Cruz, L. (2012) · Materials Science and Engineering C · doi:10.1016/j.msec.2012.12.040 · Cited by 83
Basil oil-nanoemulsions: Development, cytotoxicity and evaluation of antioxidant and antimicrobial potential
Gündel, S. D. S., Velho, M. C., Diefenthaler, M. K., Favarin, F. R., Copetti, P. M., Fogaça, A. D. O., Klein, B., Wagner, R. C., Gündel, A., Sagrillo, M. R., et al. (2018) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2018.05.038 · Cited by 81
Self-citation
Lipid Nanoparticles for the Topical Delivery of Retinoids and Derivatives
Morales, J. O., Valdés, K., Morales, J. O., & Oyarzun-Ampuero, F. A. (2015) · Nanomedicine · doi:10.2217/nnm.14.159 · Cited by 67
The use of Brazilian vegetable oils in nanoemulsions: an update on preparation and biological applications
Bajerski, L., Michels, L. R., Colomé, L. M., Bender, E. A., Freddo, R. J., Bruxel, F., & Haas, S. E. (2016) · Brazilian Journal of Pharmaceutical Sciences · doi:10.1590/s1984-82502016000300001 · Cited by 66
An efficient liposome based method for antioxidants encapsulation
Paini, M., Daly, S. R., Aliakbarian, B., Fathi, A., Arab‐Tehrany, E., Perego, P., Dehghani, F., & Valtchev, P. (2015) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2015.10.038 · Cited by 63
Dithranol-loaded lipid-core nanocapsules improve the photostability and reduce the in vitro irritation potential of this drug
Savian, A. L., Rodrigues, D. G. B., Weber, J., Ribeiro, R. F., Motta, M. H., Schaffazick, S. R., Adams, A. I. H., de Andrade, D. F., Beck, R. C. R., & da Silva, C. B. (2014) · Materials Science and Engineering C · doi:10.1016/j.msec.2014.10.011 · Cited by 60
Self-citation
Polymeric nanocapsules with SEDDS oil-core for the controlled and enhanced oral absorption of cyclosporine
Park, M.-J., Balakrishnan, P., & Yang, S. (2012) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.10.018 · Cited by 56
Felodipine loaded PLGA nanoparticles: preparation, physicochemical characterization and in vivo toxicity study
Jana, U., Mohanty, A. K., Pal, S. L., Manna, P. K., & Mohanta, G. P. (2014) · Nano Convergence · doi:10.1186/s40580-014-0031-5 · Cited by 55
Evaluation of photodynamic activity, photostability and in vitro drug release of zinc phthalocyanine-loaded nanocapsules
de Souza, T. D., Ziembowicz, F. I., Müller, D. F., Lauermann, S. C., Kloster, C. L., Santos, R. C. V., Lopes, L. Q. S., Ourique, A. F., Machado, G., & Villetti, M. A. (2015) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2015.12.006 · Cited by 55
Self-citation
Influence of Melaleuca alternifolia oil nanoparticles on aspects of Pseudomonas aeruginosa biofilm
Comin, V. M., Lopes, L. Q. S., Quatrin, P. M., de Souza, M. E., Bonez, P. C., Pintos, F. G., Raffin, R. P., Vaucher, R. D. A., Martinez, D. S. T., & Santos, R. C. V. (2016) · Microbial Pathogenesis · doi:10.1016/j.micpath.2016.01.019 · Cited by 56
Preparation and characterization of nebivolol nanoparticles using Eudragit® RS100
Jana, U., Mohanty, A. K., Manna, P. K., & Mohanta, G. P. (2013) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2013.09.001 · Cited by 54
Co-nanoencapsulation of antimalarial drugs increases their in vitro efficacy against Plasmodium falciparum and decreases their toxicity to Caenorhabditis elegans
Pereira, K. V., Maciel, T. R., Forno, A. H. D., Teixeira, F. E. G., da Fonseca, A. L., Varotti, F. D. P., Fajardo, A. R., Ávila, D. S., & Haas, S. E. (2018) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2018.03.014 · Cited by 53
Photostabilization strategies of photosensitive drugs
Coelho, L., Almeida, I. F., Lobo, J. M. S., & Silva, J. P. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.02.012 · Cited by 54
Formulation development, stability and anticancer efficacy of core-shell cyclodextrin nanocapsules for oral chemotherapy with camptothecin
Ünal, H., Öztürk, N., & Bilensoy, E. (2015) · Beilstein Journal of Organic Chemistry · doi:10.3762/bjoc.11.22 · Cited by 52
Development and Characterization of Nisin Nanoparticles as Potential Alternative for the Recurrent Vaginal Candidiasis Treatment
de Abreu, L. C. L., Todaro, V., Sathler, P. C., da Silva, L. C. R. P., do Carmo, F. A., Costa, C. M., Toma, H. K., Castro, H. C., Rodrigues, C. R., de Sousa, V. P., et al. (2016) · AAPS PharmSciTech · doi:10.1208/s12249-016-0477-3 · Cited by 52
Recent developments of nanoparticle-delivered dosage forms for buccal delivery
Tran, P. H. L., Duan, W., & Tran, T. T. D. (2019) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2019.118697 · Cited by 51
Liposome-based nanocapsules for the controlled release of dietary curcumin: PDDA and silica nanoparticle-coated DMPC liposomes enhance the fluorescence efficiency and anticancer activity of curcumin
Othman, A. K., Kurdi, R. E., Badran, A., Mesmar, J. E., Baydoun, E., & Patra, D. (2022) · RSC Advances · doi:10.1039/d2ra00071g · Cited by 51
Dual drug-loaded nanoparticles on self-integrated scaffold for controlled delivery
Kim, S., Bennet, Marimuthu, M., & An (2012) · International Journal of Nanomedicine · doi:10.2147/ijn.s32800 · Cited by 51
Polymers in topical delivery of anti-psoriatic medications and other topical agents in overcoming the barriers of conventional treatment strategies
Yadav, K., Soni, A., Singh, D., & Singh, M. R. (2021) · Progress in Biomaterials · doi:10.1007/s40204-021-00154-7 · Cited by 51
α-bisabolol-loaded lipid-core nanocapsules reduce lipopolysaccharide-induced pulmonary inflammation in mice
D’Almeida, A. P. L., de Oliveira, M. P., de Souza, É., Coutinho, D. D. S., Ciambarella, B. T., Gomes, C., Terroso, T. F., Guterres, S. S., Pohlmann, A. R., Silva, P., et al. (2017) · International Journal of Nanomedicine · doi:10.2147/ijn.s130798 · Cited by 50
Self-citation
Optimization of Curcuma Oil/Quinine-Loaded Nanocapsules for Malaria Treatment
Gomes, G. S., Maciel, T. R., Piegas, E. M., Michels, L. R., Colomé, L. M., Freddo, R. J., Ávila, D. S., Gündel, A., & Haas, S. E. (2017) · AAPS PharmSciTech · doi:10.1208/s12249-017-0854-6 · Cited by 50
Photo-responsive polymer nanocapsules
Marturano, V., Cerruti, P., Carfagna, C., Giamberini, M., Tylkowski, B., & Ambrogi, V. (2015) · Polymer · doi:10.1016/j.polymer.2015.05.059 · Cited by 50
Retinoids: new use by innovative drug-delivery systems
Trapasso, E., Cosco, D., Celia, C., Fresta, M., & Paolino, D. (2009) · Expert Opinion on Drug Delivery · doi:10.1517/17425240902832827 · Cited by 49
Development and Evaluation of in-situ Nasal Gel Formulations of Nanosized Transferosomal Sumatriptan: Design, Optimization, in vitro and in vivo Evaluation
Omar, M. M., Eleraky, N. E., Sisi, A. M. E., & Hasan, O. A. (2019) · Drug Design Development and Therapy · doi:10.2147/dddt.s235004 · Cited by 49
Retracted
Development of a nanoparticle-based system for the delivery of retinoic acid into macrophages
Almouazen, E., Bourgeois, S., Boussaïd, A., Valot, P., Malleval, C., Fessi, H., Nataf, S., & Briançon, S. (2012) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.03.025 · Cited by 47
Nanocarrier Systems for Transdermal Drug Delivery
Escobar‐Chávez, J. J., Rodríguez-Cruz, I. M., Luísa, C., Diaz, R., Luisa, A., & Casas, N. H. (2012) · InTech eBooks · doi:10.5772/50314 · Cited by 47
Spray-dried powders improve the controlled release of antifungal tioconazole-loaded polymeric nanocapsules compared to with lyophilized products
Ribeiro, R. F., Motta, M. H., Härter, A. P. G., Flores, F. C., Beck, R. C. R., Schaffazick, S. R., & da Silva, C. D. B. (2015) · Materials Science and Engineering C · doi:10.1016/j.msec.2015.10.035 · Cited by 47
Self-citation
Novel tretinoin formulations: a drug-in-cyclodextrin-in-liposome approach
Ascenso, A., Cruz, M., Euletério, C., Carvalho, F. A., Santos, N. C., Cabral-Marques, H. M., & Simões, S. (2013) · Journal of Liposome Research · doi:10.3109/08982104.2013.788026 · Cited by 46
Model validation for precipitation in solvent-displacement processes
Pasquale, N. D., Marchisio, D. L., & Barresi, A. (2012) · Chemical Engineering Science · doi:10.1016/j.ces.2012.08.043 · Cited by 46
Nanodiamond applications in skin preparations
Namdar, R., & Nafisi, S. (2018) · Drug Discovery Today · doi:10.1016/j.drudis.2018.04.006 · Cited by 46
Porphyrin Derivative Nanoformulations for Therapy and Antiparasitic Agents
Deda, D. K., Iglesias, B. A., Alves, E., Araki, K., & Garcia, C. R. S. (2020) · Molecules · doi:10.3390/molecules25092080 · Cited by 45
Contribution of Nanoscience Research in Antioxidants Delivery Used in Nutricosmetic Sector
Dini, I. (2022) · Antioxidants · doi:10.3390/antiox11030563 · Cited by 46
Benzocaine loaded biodegradable poly-(d,l-lactide-co-glycolide) nanocapsules: factorial design and characterization
Moraes, C. M., de Matos, A. P., de Paula, E., Rosa, A. H., & Fraceto, L. F. (2009) · Materials Science and Engineering B · doi:10.1016/j.mseb.2009.06.011 · Cited by 43
Vegetable oils as core of cationic polymeric nanocapsules: influence on the physicochemical properties
Contri, R. V., Ribeiro, K. L. F., Fiel, L. A., Pohlmann, A. R., & Guterres, S. S. (2012) · Journal of Experimental Nanoscience · doi:10.1080/17458080.2011.620019 · Cited by 42
Self-citation
Drug delivery applications of poly-γ-glutamic acid
Balogun‐Agbaje, O. A., Odeniyi, O. A., & Odeniyi, M. A. (2021) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-021-00280-w · Cited by 41
Diphenyl diselenide loaded poly(ε-caprolactone) nanocapsules with selective antimelanoma activity: Development and cytotoxic evaluation
Ferreira, L. M., Cervi, V. F., Sari, M. H. M., Barbieri, A. V., Ramos, A. P., Copetti, P. M., de Brum, G. F., do Nascimento, K. G., Nadal, J. M., Farago, P. V., et al. (2018) · Materials Science and Engineering C · doi:10.1016/j.msec.2018.05.014 · Cited by 40
Transport of Substances and Nanoparticles across the Skin and in Vitro Models to Evaluate Skin Permeation and/or Penetration
Contri, R. V., Fiel, L. A., Pohlmann, A. R., Guterres, S. S., & Beck, R. C. R. (2011) · Springer eBooks · doi:10.1007/978-3-642-19792-5_1 · Cited by 40
Self-citation
A promising nystatin nanocapsular hydrogel as an antifungal polymeric carrier for the treatment of topical candidiasis
AbouSamra, M. M., Basha, M., Awad, G. E. A., & Mansy, S. S. (2018) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2018.12.014 · Cited by 39
Thermal and ultraviolet–visible light stability kinetics of co-nanoencapsulated carotenoids
da Silva, M. M., Paese, K., Guterres, S. S., Pohlmann, A. R., Rutz, J. K., Cantillano, R. F. F., Nora, L., & Rios, A. D. O. (2017) · Food and Bioproducts Processing · doi:10.1016/j.fbp.2017.05.004 · Cited by 39
Self-citation
Nanoencapsulation of Rose-Hip Oil Prevents Oil Oxidation and Allows Obtainment of Gel and Film Topical Formulations
Contri, R. V., Külkamp‐Guerreiro, I. C., da Silva, S. J., Frank, L. A., Pohlmann, A. R., & Guterres, S. S. (2015) · AAPS PharmSciTech · doi:10.1208/s12249-015-0379-9 · Cited by 38
Self-citation
Retinyl acetate-loaded nanoparticles: Dermal penetration and release of the retinyl acetate
Arayachukeat, S., Wanichwecharungruang, S. P., & Tree‐Udom, T. (2010) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2010.11.019 · Cited by 38
Polymeric nanotherapeutics acting at special regions of body
Feczkó, T. (2021) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2021.102597 · Cited by 39
Preparation of Rutin-liposome Drug Delivery Systems and Evaluation on Their in vitro Antioxidant Activity
Guo, Y. C., Shen, L., Lu, Y.-F., Li, H., Min, K., Li, L., Yu, C., & Zheng, X. (2016) · Chinese Herbal Medicines · doi:10.1016/s1674-6384(16)60065-5 · Cited by 38
A Transdermal Delivery System to Enhance Quercetin Nanoparticle Permeability
Bennet, D., & Kim, S. (2012) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856212x630258 · Cited by 37
Advances in cosmeceutical nanotechnology for hyperpigmentation treatment
Tangau, M. J., Chong, Y. K., & Yeong, K. Y. (2022) · Journal of Nanoparticle Research · doi:10.1007/s11051-022-05534-z · Cited by 40
Encapsulation in lipid-core nanocapsules overcomes lung cancer cell resistance to tretinoin
Schultze, E., Ourique, A. F., Yurgel, V. C., Begnini, K. R., Thurow, H. S., de Leon, P. M. M., Campos, V. F., Dellagostin, O. A., Guterres, S. S., Pohlmann, A. R., et al. (2014) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2014.02.003 · Cited by 35
Self-citation
Potential Role of Growth Factors Controlled Release in Achieving Enhanced Neuronal Trans-differentiation from Mesenchymal Stem Cells for Neural Tissue Repair and Regeneration
Gupta, A., & Singh, S. (2021) · Molecular Neurobiology · doi:10.1007/s12035-021-02646-w · Cited by 36
Nanotechnology improves the therapeutic efficacy of Melaleuca alternifolia essential oil in experimentally infected Rhamdia quelen with Pseudomonas aeruginosa
Souza, C. F., Baldissera, M. D., Santos, R. C. V., Raffin, R. P., & Baldisserotto, B. (2017) · Aquaculture · doi:10.1016/j.aquaculture.2017.02.014 · Cited by 32
Topical Application of Nanostructures: Solid Lipid, Polymeric and Metallic Nanoparticles
Durán, N., Teixeira, Z., & Marcato, P. D. (2011) · Springer eBooks · doi:10.1007/978-3-642-19792-5_4 · Cited by 31
Albumin-covered lipid nanocapsules exhibit enhanced uptake performance by breast-tumor cells
Galisteo-González, F., Molina-Bolívar, J. A., Navarro-Marchal, S. A., Boulaiz, H., Aguilera-Garrido, A., Ramírez, A., & Marchal, J. A. (2018) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2018.02.024 · Cited by 31
Advances in polymeric nano-delivery systems targeting hair follicles for the treatment of acne
Lei, Y., Jiang, W., Peng, C., Wu, D., Wu, J., Xu, Y., Yan, H. J., & Xia, X. (2024) · Drug Delivery · doi:10.1080/10717544.2024.2372269 · Cited by 30
Nanocapsules by Miniemulsion Polymerization with Biodegradable Surfactant and Hydrophobe
Rômio, A. P., Sayer, C., de Araújo, P. H. H., Al-Haydari, M. D., Wu, L., & da Rocha, S. R. P. (2009) · Macromolecular Chemistry and Physics · doi:10.1002/macp.200800593 · Cited by 29
Incorporation of 3,3′-Diindolylmethane into Nanocapsules Improves Its Photostability, Radical Scavenging Capacity, and Cytotoxicity Against Glioma Cells
Mattiazzi, J., Sari, M. H. M., Lautenchleger, R., Prá, M. D., Braganhol, E., & Cruz, L. (2019) · AAPS PharmSciTech · doi:10.1208/s12249-018-1240-8 · Cited by 27
Trazodone Loaded Lipid Core Poly (ε-caprolactone) Nanocapsules: Development, Characterization and in Vivo Antidepressant Effect Evaluation
Elhesaisy, N. A., & Swidan, S. A. (2020) · Scientific Reports · doi:10.1038/s41598-020-58803-z · Cited by 27
Influence of the type of vegetable oil on the drug release profile from lipid-core nanocapsules andin vivogenotoxicity study
Rigo, L. A., Frescura, V. D.-S., Fiel, L. A., Coradini, K., Ourique, A. F., Emanuelli, T., Quatrin, A., Tedesco, S. B., da Silva, C. B., Guterres, S. S., et al. (2013) · Pharmaceutical Development and Technology · doi:10.3109/10837450.2013.829097 · Cited by 27
Self-citation
Polymeric Nanoparticles Based Topical Drug Delivery: An Overview
Rangari, A. T. (2015) · Asian journal of biomedical and pharmaceutical sciences · doi:10.15272/ajbps.v5i47.718 · Cited by 26
Unveiling the mechanisms for the development of rosehip-based dermatological products: an updated review
Oargă, D. P., Cornea‐Cipcigan, M., & Cordea, M. I. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1390419 · Cited by 32
Exploration of and insights into advanced topical nanocarrier systems for the treatment of psoriasis
Zhang, M., Hong, S., Sun, X., Zhou, Y., Luo, Y., Liu, L., Wang, J., Wang, C., Lin, N., & Li, X. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.1017126 · Cited by 24
Size-dependent endocytosis and a dynamic-release model of nanoparticles
Pan, R., Liu, G., Li, Y., Wei, Y., Li, S., & Tao, L. (2018) · Nanoscale · doi:10.1039/c8nr00830b · Cited by 24
Desonide nanoencapsulation with açai oil as oil core: Physicochemical characterization, photostability study and in vitro phototoxicity evaluation
Rosa, P., Friedrich, M. L., dos Santos, J., Nogueira-Librelotto, D. R., Maurer, L. H., Emanuelli, T., da Silva, C. D. B., & Adams, A. I. H. (2019) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2019.111606 · Cited by 23
Improved photostability and cytotoxic effect of coenzyme Q10 by its association with vitamin E acetate in polymeric nanocapsules
Pegoraro, N. S., Mattiazzi, J., da Silveira, E. F., Azambuja, J. H., Braganhol, E., & Cruz, L. (2017) · Pharmaceutical Development and Technology · doi:10.1080/10837450.2017.1332641 · Cited by 23
Nanotechnology-Based Mucoadhesive and Mucus-Penetrating Drug-Delivery Systems for Transbuccal Drug Delivery
Desai, D. D., Manikkath, J., Lad, H., Kulkarni, M., Manikkath, A., & Radhakrishnan, R. A. (2023) · Nanomedicine · doi:10.2217/nnm-2023-0180 · Cited by 25
Comparative Study of Reversed-Phase High-Performance Liquid Chromatography and Ultraviolet–Visible Spectrophotometry to Determine Doxorubicin in pH-Sensitive Nanoparticles
Scheeren, L. E., Nogueira-Librelotto, D. R., Fernandes, J. R., Macedo, L. B., Marcolino, A. I. P., Vinardell, M. P., & Rolim, C. M. B. (2017) · Analytical Letters · doi:10.1080/00032719.2017.1380034 · Cited by 21
Influence of the addition of microsphere load amoxicillin in the physical, chemical and biological properties of an experimental endodontic sealer
Dornelles, N. B., Collares, F. M., Genari, B., Balbinot, G. D. S., Samuel, S. M. W., Arthur, R. A., Visioli, F., Guterres, S. S., & Leitune, V. C. B. (2017) · Journal of Dentistry · doi:10.1016/j.jdent.2017.10.010 · Cited by 20
Self-citation
Importance of Nanomaterials in Engineering Application
Jun, L. Y., Khan, F. S. A., Mubarak, N. M., Yon, L. S., Bing, C. H., Khalid, M., & Abdullah, E. C. (2020) · Engineering materials · doi:10.1007/978-3-030-62761-4_1 · Cited by 18
Design and Optimization of Cationic Nanocapsules for Topical Delivery of Tretinoin: Application of the Box‐Behnken Design, In Vitro Evaluation, and Ex Vivo Skin Deposition Study
Ebrahimi, S., Mahjub, R., Haddadi, R., & Vafaei, S. Y. (2021) · BioMed Research International · doi:10.1155/2021/4603545 · Cited by 16
Advances in nanobiomaterials for topical administrations: new galenic and cosmetic formulations
Severino, P. B., Fangueiro, J. F., Chaud, M. V., Cordeiro, J., Silva, A. M., & Souto, E. B. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-42868-2.00001-2 · Cited by 16
Intracellular Delivery of Poorly Soluble Polyphenols: Elucidating the Interplay of Self-Assembling Nanocarriers and Human Chondrocytes
Kann, B., Spengler, C., Coradini, K., Rigo, L. A., Bennink, M. L., Jacobs, K., Offerhaus, H. L., Beck, R. C. R., & Windbergs, M. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b00199 · Cited by 16
Self-citation
Polymeric Nanoparticles
Guterres, S. S., Paese, K., & Pohlmann, A. R. (2019) · Springer eBooks · doi:10.1007/978-3-030-16573-4_5 · Cited by 15
Self-citation
Olive-oil nanocapsules stabilized by HSA: influence of processing variables on particle properties
Molina-Bolívar, J. A., & Galisteo-González, F. (2015) · Journal of Nanoparticle Research · doi:10.1007/s11051-015-3192-1 · Cited by 15
Flutamide-Loaded Zein Nanocapsule Hydrogel, a Promising Dermal Delivery System for Pilosebaceous Unit Disorders
Sallam, M. A., & Elzoghby, A. O. (2018) · AAPS PharmSciTech · doi:10.1208/s12249-018-1087-z · Cited by 15
Bionanotechnology in Agriculture, Food, Cosmetic and Cosmeceutical
Lee, Y., & Moon, J. (2020) · Springer eBooks · doi:10.1007/978-981-15-1293-3_11 · Cited by 13
Polymeric Drug Delivery Systems for Encapsulating Hydrophobic Drugs
Ahmed, N., Mora‐Huertas, C. E., Jaafar‐Maalej, C., Fessi, H., & Elaı̈ssari, A. (2013) · Wiley eBooks · doi:10.1002/9781118444726.ch5 · Cited by 13
Psoriasis: Unraveling Disease Mechanisms and Advancing Pharmacological and Nanotechnological Treatments
Miao, M., Yan, J., Sun, Y., Liu, J., & Guo, S. (2025) · Journal of Inflammation Research · doi:10.2147/jir.s506103 · Cited by 12
Breakthrough Opportunities of Nanotheranostics in Psoriasis: From Pathogenesis to Management Strategy
Singh, A., Kumar, P., & Sharma, H. (2024) · Infectious Disorders - Drug Targets · doi:10.2174/0118715265298802240603120251 · Cited by 16
2-(2-Methoxyphenyl)-3-((Piperidin-1-yl)ethyl)thiazolidin-4-One-Loaded Polymeric Nanocapsules: In Vitro Antiglioma Activity and In Vivo Toxicity Evaluation
da Silveira, E. F., Ferreira, L. M., Gehrcke, M., Cruz, L., Pedra, N. S., Ramos, P. T. S., Bona, N. P., Soares, M. S. P., Rodrigues, R., Spanevello, R. M., et al. (2019) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-019-00678-4 · Cited by 11
Pharmacokinetic profiles, cytotoxicity, and redox metabolism of free and nanoencapsulated curcumin
Copetti, P. M., Bissacotti, B. F., Gündel, S. D. S., Bottari, N. B., Sagrillo, M. R., Machado, A. K., Ourique, A. F., Schetinger, M. R. C., & Silva, A. S. D. (2022) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2022.103352 · Cited by 11
Self-citation

Authors: Ourique, A. F., Pohlmann, A. R., Guterres, S. S., & Beck, R. C. R.
Affiliations: Universidade Federal de Santa Maria (BR)
Universidade Federal do Rio Grande do Sul (BR)
Corresponding author: Beck, R.C.R.
ORCID: Ourique, A.F.
Pohlmann, A.R.
Beck, R.C.R.
Venue: International Journal of Pharmaceutics
Publisher: Elsevier BV
Published: 2008-03
Volume: 352
Issue: 1-2
Pages: 1-4
ISSN: 0378-5173 (ISSN-L)
DOI: 10.1016/j.ijpharm.2007.12.035
OpenAlex: W2006560775
Cited by: 145
References: 29
Citations by year: 2026: 2 · 2025: 5 · 2024: 5 · 2023: 2 · 2022: 10 · 2021: 8 · 2020: 9 · 2019: 7 · 2018: 11 · 2017: 10 · 2016: 12 · 2015: 12 · 2014: 8 · 2013: 10 · 2012: 12
FWCI: 5.16
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: International Journal of Pharmaceutics (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Keywords: all-trans retinoic acid, nanocapsules, polycaprolactone, interfacial deposition, photostability, photodegradation, encapsulation efficiency, triglycerides, sunflower oil, topical drug delivery
MeSH terms: Sunflower Oil, Caprylates, Chemistry, Pharmaceutical, Decanoic Acids, Dermatologic Agents, Drug Compounding, Drug Stability, Feasibility Studies, Half-Life, Kinetics, Particle Size, Photolysis, Plant Oils, Polyesters, Solubility, Technology, Pharmaceutical, Tretinoin, Triglycerides, Ultraviolet Rays, Nanocapsules

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Tretinoin-loaded nanocapsules: Preparation, physicochemical characterization, and photostability study

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks