Nanocosmetics and Nanomedicines

Ruy Carlos Ruver Beck; Adriana Raffin Pohlmann; Sı́lvia Stanisçuaski Guterres

doi:10.1007/978-3-642-19792-5

Cited by 120Advancements in Transdermal Drug DeliveryAdvanced Drug Delivery SystemsNanoparticle-Based Drug Delivery

Nanocosmetics and Nanomedicines

Ruy Carlos Ruver Beck, Adriana Raffin Pohlmann, Sı́lvia Stanisçuaski Guterres·2011·Springer eBooks

DOI 10.1007/978-3-642-19792-5

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Cosmeceuticals have active components that affect biological processes of the skin, designed to go deeper into the epidermis and provide therapeutic effects like wrinkle reduction, increased skin suppleness, and hyperpigmentation treatment.
“Cosmeceuticals, on the other hand, are goods that fall in between pharmaceuticals and cosmetics and have active components that affect the biological processes of the skin. Retinoids, peptides, and antioxidants are examples of active ingredients that are designed to go deeper into the epidermis and provide therapeutic effects like wrinkle reduction, increased skin suppleness, and hyperpigmentation”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
Conventional cosmetics are mostly used to improve appearance, and their effects are usually superficial and restricted to the skin's exterior layers.
“Conventional cosmetics, like moisturizers, lipsticks, and foundations, are mostly used to improve appearance. Their effects are usually superficial and restricted to the skin's exterior layers.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
Cosmeceuticals are topical medications that affect the function and appearance of the skin and operate pharmacologically or physiologically to have a long-lasting impact.
“Cosmeceuticals refer to topical medications that affect the function and appearance of the skin; these goods combine the terms “cosmetic” and “pharmaceutical,” making them more than just basic cosmetics. According to science, cosmeceuticals are like pharmaceuticals in that they operate pharmacologically or physiologically to have a long-lasting impact [12-15].”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
According to Pearson (2018), active ingredients from food were thought to be crucial for both the skin's anti-aging benefits and protection against injury.
“According to Pearson (2018), these active ingredients were thought to be crucial for both the skin's anti-aging benefits and protection against injury.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
'Cosmeceuticals' are not officially recognized as a category by the U.S. FDA, resulting in regulatory variations around the world.
“However, “cosmeceuticals” are not officially recognized as a category by the United States Food and Drug Administration (U. S. FDA), which results in regulatory variations around the world.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]

Vitamin C helps promote collagen formation and defend against oxidative stress.
“The effectiveness of cosmeceuticals is confirmed by scientific study; for example, studies show that vitamin C helps to promote collagen formation and defend against oxidative stress.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
The benefits of components generated from food and their effects on human health were discussed in the 1980s, when this idea began to garner greater attention.
“The benefits of components generated from food and their effects on human health were discussed in the 1980s, when this idea began to garner greater attention [15-17].”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
Little is known about the long-term impacts of nanoscale particles on ecosystems, which makes it difficult to ensure that their usage in commonplace products is sustainable.
“Furthermore, little is known about the long-term impacts of nanoscale particles on ecosystems, which makes it difficult to ensure that their usage in commonplace products is sustainable [15].”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
Nanoparticles can enter the skin more readily than traditional components because of their small size, which may result in systemic exposure.
“Nanoparticles have the ability to enter the skin more readily than traditional components because of their small size, which may result in systemic exposure.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
The use of nanoparticles in cosmetics has environmental problems in addition to human health ones.
“On the other hand, the use of nanoparticles in cosmetics has environmental problems in addition to human health ones.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
The possibility of toxicity is one of the main issues with the use of nanomaterials in cosmetics.
“The possibility of toxicity is one of the main issues with the use of nanomaterials in cosmetics.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
Many cosmetic products prepared using nanotechnology are available in the market.
“Nowadays, a lot of Cosmetic Products prepared using Nanotechnology are available in the market.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
Cosmetics that contain nanomaterials have the potential to build up in the environment and harm aquatic life when they wash off into water systems.
“Cosmetics that contain nanomaterials have the potential to build up in the environment and harm aquatic life when they wash off into water systems.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
Nanoparticles have the potential to reach the bloodstream and build up in tissues, where they could eventually have negative consequences.
“The potential for these substances to reach the bloodstream and build up in tissues, where they could eventually have negative consequences, is a worry.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
Nanomaterials in cosmetics raise safety issues, chiefly possible toxicity and biological interactions.
“Although nanomaterials have several advantages for cosmetic goods, their application raises a number of safety issues, chief among them being their possible toxicity and biological interactions.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
Cellular toxicity and skin penetration are two of the main human safety issues that need to be considered.
“Cellular toxicity and skin penetration are two of the main human safety issues that need to be considered [15].”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]
Nanoparticles are more reactive and able to interact with their surroundings due to their small size and large surface area.
“Nanoparticles are more reactive and able to interact with their surroundings due to their small size and large surface area.”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [15]

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Anti-biofilm activity of chitosan gels formulated with silver nanoparticles and their cytotoxic effect on human fibroblasts
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Cutaneous biocompatible rutin-loaded gelatin-based nanoparticles increase the SPF of the association of UVA and UVB filters
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Optimization of the Conditions of Solid Lipid Nanoparticles (SLN) Synthesis
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PVA-Based Electrospun Materials—A Promising Route to Designing Nanofiber Mats with Desired Morphological Shape—A Review
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Recent advancements in nanotechnological strategies in selection, design and delivery of biomolecules for skin regeneration
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Poly(lactic acid) nanocapsules containing lemongrass essential oil for postharvest decay control: In vitro and in vivo evaluation against phytopathogenic fungi
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Encapsulation of eugenol rich clove extract in solid lipid carriers
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Quality by design driven development of resveratrol loaded ethosomal hydrogel for improved dermatological benefits via enhanced skin permeation and retention
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When Sustainable Nanochemistry Meets Agriculture: Lignin Nanocapsules for Bioactive Compound Delivery to Plantlets
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Two-step sequential cross-linking of sugar beet pectin for transforming zein nanoparticle-based Pickering emulsions to emulgels
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Hyaluronan polymeric micelles for topical drug delivery
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Nanotechnology in cosmetics pros and cons
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Vesicular systems for dermal and transdermal drug delivery
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Nanotechnology: A Promising Tool Towards Wound Healing
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A Relevant Screening of Organic Contaminants Present on Freshwater and Pre-Production Microplastics
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Lipid Nanoparticles Based Cosmetics with Potential Application in Alleviating Skin Disorders
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Nanotechnology-Based Cosmetics for Hair Care
Rosen, J. M., Landriscina, A., & Friedman, A. (2015) · Cosmetics · doi:10.3390/cosmetics2030211 · Cited by 75 · see citing works
Nanoparticles containing curcuminoids (Curcuma longa): development of topical delivery formulation
Zamarioli, C. M., Martins, R. M., de Carvalho, E. C., & de Freitas, L. A. P. (2015) · Revista Brasileira de Farmacognosia · doi:10.1016/j.bjp.2014.11.010 · Cited by 74 · see citing works
Lipid based nanocarriers: A novel paradigm for topical antifungal therapy
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Films based on neutralized chitosan citrate as innovative composition for cosmetic application
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Novel nanotechnological approaches for treatment of skin-aging
Sharma, A., Kuhad, A., & Bhandari, R. (2022) · Journal of Tissue Viability · doi:10.1016/j.jtv.2022.04.010 · Cited by 65 · see citing works
Nano carriers for nitric oxide delivery and its potential applications in plant physiological process: A mini review
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Effects of process parameters on the colloidal properties of polycaprolactone microparticles prepared by double emulsion like process
Ibraheem, D., Iqbal, M., Agusti, G., Fessi, H., & Elaı̈ssari, A. (2014) · Colloids and Surfaces A Physicochemical and Engineering Aspects · doi:10.1016/j.colsurfa.2014.01.012 · Cited by 61 · see citing works
Skin absorption of inorganic nanoparticles and their toxicity: A review
Saweres-Argüelles, C., Ramírez-Novillo, I., Vergara‐Barberán, M., Carrasco‐Correa, E. J., Lerma-García, M. J., & Simó‐Alfonso, E. F. (2022) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2022.12.010 · Cited by 60 · see citing works
Azelaic acid-loaded nanoemulsion with hyaluronic acid – a new strategy to treat hyperpigmentary skin disorders
Berlitz, S. J., Villa, D. D., Inácio, L. A. M., Davies, S., Zatta, K. C., Guterres, S. S., & Külkamp‐Guerreiro, I. C. (2019) · Drug Development and Industrial Pharmacy · doi:10.1080/03639045.2019.1569032 · Cited by 59 · see citing works
Self-citation
Anti-inflammatory Effect from a Hydrogel Containing Nanoemulsified Copaiba oil (Copaifera multijuga Hayne)
Lucca, L. G., de Matos, S. P., Kreutz, T., Teixeira, H. F., da Veiga, V. F., de Araújo, B. V., Limberger, R. P., & Koester, L. (2017) · AAPS PharmSciTech · doi:10.1208/s12249-017-0862-6 · Cited by 57 · see citing works
In Vitro Drug Dissolution/Permeation Testing of Nanocarriers for Skin Application: a Comprehensive Review
Sheshala, R., Anuar, N. K., Samah, N. H. A., & Wong, T. W. (2019) · AAPS PharmSciTech · doi:10.1208/s12249-019-1362-7 · Cited by 57 · see citing works
An emerging technology in lipid research for targeting hydrophilic drugs to the skin in the treatment of hyperpigmentation disorders: kojic acid-solid lipid nanoparticles
Khezri, K., Saeedi, M., Morteza‐Semnani, K., Âkbari, J., & Rostamkalaei, S. S. (2020) · Artificial Cells Nanomedicine and Biotechnology · doi:10.1080/21691401.2020.1770271 · Cited by 56 · see citing works
Topical curcumin-loaded hydrogels obtained using galactomannan from Schizolobium parahybae and xanthan
Koop, H. S., de Freitas, R. A., de Souza, M. M., Savi-Jr., R., & Silveira, J. L. M. (2014) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2014.07.043 · Cited by 54 · see citing works
Use of Photosensitizers in Semisolid Formulations for Microbial Photodynamic Inactivation
González‐Delgado, J. A., Kennedy, P. J., Ferreira, M., Tomé, J. P. C., & Sarmento, B. F. C. C. (2015) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5b01129 · Cited by 54 · see citing works
Advances in biological nano-phospholipid vesicles for transdermal delivery: A review on applications
Mirtaleb, M. S., Khodabandeh, M., Ekrami, E., & Mirtaleb, A. (2021) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2021.102331 · Cited by 50 · see citing works
Development and evaluation of the effect of ethanol and surfactant in vesicular carriers on Lamivudine permeation through the skin
Sudhakar, K., Mishra, V. K., Jain, S., Rompicherla, N. C., Malviya, N., & Tambuwala, M. M. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.121226 · Cited by 48 · see citing works
Finding Nano: Challenges Involved in Monitoring the Presence and Fate of Engineered Titanium Dioxide Nanoparticles in Aquatic Environments
Heilgeist, S., Sekine, R., Sahin, O., & Stewart, R. A. (2021) · Water · doi:10.3390/w13050734 · Cited by 46 · see citing works
Potential enhancement of metformin hydrochloride in solidified reverse micellar solution-based PEGylated lipid nanoparticles targeting therapeutic efficacy in diabetes treatment
Kenechukwu, F. C., Nnamani, D. O., Duhu, J. C., Nmesirionye, B. U., Momoh, M. A., Akpa, P. A., & Attama, A. A. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e09099 · Cited by 40 · see citing works
Nanoparticles for cosmetic use and its application
Chiari‐Andréo, B. G., de Almeida-Cincotto, M. G. J., Oshiro, J. A., Taniguchi, C. Y. Y., Chiavacci, L. A., & Isaac, V. L. B. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816504-1.00013-2 · Cited by 38 · see citing works
Development and Characterization of Vitamin A-Loaded Solid Lipid Nanoparticles for Topical Application
Argimón, M., Romero, M., Miranda, P., Mombrú, Á. W., Miraballes, I., Zimet, P., & Pardo, H. (2016) · Journal of the Brazilian Chemical Society · doi:10.21577/0103-5053.20160276 · Cited by 31 · see citing works
Development of Functional Hybrid Polymers and Gel Materials for Sustainable Membrane-Based Water Treatment Technology: How to Combine Greener and Cleaner Approaches
Rando, G., Sfameni, S., & Plutino, M. R. (2022) · Gels · doi:10.3390/gels9010009 · Cited by 31 · see citing works
Nanoparticle platforms for dermal antiaging technologies: Insights in cellular and molecular mechanisms
Bhatia, E., Kumari, D., Sharma, S., Ahamad, N., & Banerjee, R. (2021) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1746 · Cited by 30 · see citing works
Silica nanoparticles catalyse the formation of silica nanocapsules in a surfactant-free emulsion system
Zhao, Y., Chen, Z., Zhu, X., & Möller, M. (2015) · Journal of Materials Chemistry A · doi:10.1039/c5ta06947e · Cited by 30 · see citing works
An Innovative Formulation Based on Nanostructured Lipid Carriers for Imatinib Delivery: Pre-Formulation, Cellular Uptake and Cytotoxicity Studies
Gündoğdu, E., Demir, E., Ekinci, M., Özgenç, E., İlem‐Özdemir, D., Şenyiğit, Z. A., González‐Álvarez, I., & Bermejo, M. (2022) · Nanomaterials · doi:10.3390/nano12020250 · Cited by 28 · see citing works
Nanoemulsion Containing Kojic Dipalmitate and Rosehip Oil: A Promising Formulation to Treat Melasma
Zilles, J. C., Duarte, L. P., Ruaro, T. C., Zimmer, A. R., Külkamp‐Guerreiro, I. C., & Contri, R. V. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15020468 · Cited by 28 · see citing works
Lipid nanocarriers containing Passiflora edulis seeds oil intended for skin application
Krambeck, K., Santos, D. F. G., Otero-Espinar, F. J., Lobo, J. M. S., & Amaral, M. H. (2020) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2020.111057 · Cited by 27 · see citing works
NLC-Based Sunscreen Formulations with Optimized Proportion of Encapsulated and Free Filters Exhibit Enhanced UVA and UVB Photoprotection
de Araújo, M. M., Schneid, A. D. C., Oliveira, M. S., Mussi, S. V., de Freitas, M. N., Carvalho, F. C., Bernes, E. A., Faro, R., & de Azevedo, H. F. Z. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16030427 · Cited by 26 · see citing works
Vinpocetine loaded ultradeformable liposomes as fast dissolving microneedle patch: Tackling treatment challenges of dementia
Srivastava, P. K., & Thakkar, H. P. (2020) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2020.09.006 · Cited by 25 · see citing works
Nanoencapsulation potentiates the cutaneous anti-inflammatory effect of p,p′-methoxyl-diphenyl diselenide: Design, permeation, and in vivo studies of a nanotechnological-based carrageenan gum hydrogel
Sari, M. H. M., Fulco, B. C. W., Ferreira, L. M., Pegoraro, N. S., Brum, E. D. S., Casola, K. K., Marchiori, M. C. L., Oliveira, S. M., Nogueira, C. W., & Cruz, L. (2020) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2020.105500 · Cited by 23 · see citing works
Green nanotechnology for the development of nanoparticles based on alginate associated with essential and vegetable oils for application in fruits and seeds protection
dos Santos, C. M., Gonçalves, M. D. A., de Macedo, L. F., Torres, A. H. F., Marena, G. D., Chorilli, M., & Trovatti, E. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.123351 · Cited by 22 · see citing works
Fabrication and characterization of gas-assisted core-shell hydrogel nanofibers as a drug release system with antibacterial activity
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UVB photoprotective capacity of hydrogels containing dihydromyricetin nanocapsules to UV-induced DNA damage
Dalcin, A. J. F., Roggia, I., Felin, S., Vizzotto, B. S., Mitjans, M., Vinardell, M. P., Schuch, A. P., Ourique, A. F., & Gomes, P. (2020) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2020.111431 · Cited by 20 · see citing works
Submicron polymeric particles prepared by vibrational spray-drying: Semisolid formulation and skin penetration/permeation studies
Beber, T. C., de Andrade, D. F., Kann, B., Fontana, M. C., Coradini, K., Windbergs, M., & Beck, R. C. R. (2014) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2014.07.008 · Cited by 20 · see citing works
Self-citation
Lipid- and Polymer-Based Nanostructures for Cutaneous Delivery of Curcumin
Caon, T., Mazzarino, L., Simões, C. M. O., Lemos‐Senna, E., & Silva, M. A. S. (2016) · AAPS PharmSciTech · doi:10.1208/s12249-016-0554-7 · Cited by 20 · see citing works
Nanoparticles influence in skin penetration of drugs
Lemos, C. N., Pereira, F., Dalmolin, L. F., Cubayachi, C., Ramos, D. N., & Lopez, R. F. V. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813665-2.00006-5 · Cited by 20 · see citing works
Antimicrobial activity of silica coated silicon nano-tubes (SCSNT) and silica coated silicon nano-particles (SCSNP) synthesized by gas phase condensation
Tank, C. M., Raman, S., Karan, S., Gosavi, S., Lalla, N. P., Sathe, V., Berndt, R. L., Gade, W. N., Bhoraskar, S. V., & Mathe, V. L. (2013) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-013-4896-3 · Cited by 19 · see citing works
Lipid nanocarriers as skin drug delivery systems
Nava-Arzaluz, M. G., Piñón‐Segundo, E., & Ganem‐Rondero, A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816504-1.00007-7 · Cited by 19 · see citing works
QbD-driven development of dissolving microneedle patch loaded with ultradeformable liposomes encapsulated Noopept: Exploring a patient friendly, once-daily option to manage dementia
Srivastava, P. K., & Thakkar, H. P. (2021) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2021.105909 · Cited by 19 · see citing works
Encapsulation of β-lactoglobulin within calcium carbonate microparticles and subsequent in situ fabrication of protein microparticles
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Authors: Beck, R. C. R., Pohlmann, A. R., & Guterres, S. S.
Affiliations: Universidade Federal do Rio Grande do Sul (BR)
ORCID: Ruy Carlos Ruver Beck
Adriana Raffin Pohlmann
Sı́lvia Stanisçuaski Guterres
Venue: Springer eBooks
Publisher: Springer Berlin Heidelberg
Published: 2011
DOI: 10.1007/978-3-642-19792-5
OpenAlex: W2497634106
Cited by: 116
References: 573
Citations by year: 2026: 1 · 2025: 2 · 2024: 5 · 2023: 7 · 2022: 19 · 2021: 12 · 2020: 18 · 2019: 8 · 2018: 4 · 2017: 8 · 2016: 13 · 2015: 12 · 2014: 3 · 2013: 4
FWCI: 0.90
Type: book
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Springer eBooks (publishedVersion)
Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B)) (submittedVersion)
Topics: Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Keywords: nanocosmetics, nanomedicine, skin care, nanocarriers, skin delivery, topical drug delivery

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