Auditory evoked fields predict language ability and impairment in children

Oram Cardy, Janis E.; Flagg, Elissa J.; Roberts, Wendy; Roberts, Timothy P.L.

doi:10.1016/j.ijpsycho.2007.10.015

Cited by 115Language Development and DisordersNeurobiology of Language and BilingualismAutism Spectrum Disorder Research

Auditory evoked fields predict language ability and impairment in children

Oram Cardy, Janis E., Flagg, Elissa J., Roberts, Wendy, Roberts, Timothy P.L.·2008·International Journal of Psychophysiology

DOI 10.1016/j.ijpsycho.2007.10.015

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Abstract

Recent evidence suggests that a subgroup of children with autism show similarities to children with Specific Language Impairment (SLI) in the pattern of their linguistic impairments, but the source of this overlap is unclear. We examined the ability of auditory evoked magnetic fields to predict language and other developmental abilities in children and adolescents. Following standardized assessment of language ability, nonverbal IQ, and autism-associated behaviors, 110 trails of a tone were binaurally presented to 45 7-18 year olds who had typical development, autism (with LI), Asperger Syndrome (i.e., without LI), or SLI. Using a 151-channel MEG system, latency of left hemisphere (LH) and right hemisphere (RH) auditory M50 and M100 peaks was recorded. RH M50 latency (and to a lesser extent, RH M100 latency) predicted overall oral language ability, accounting for 36% of the variance. Nonverbal IQ and autism behavior ratings were not predicted by any of the evoked fields. Latency of the RH M50 was the best predictor of clinical LI (i.e., irrespective of autism diagnosis), and demonstrated 82% accuracy in predicting Receptive LI; a cutoff of 84.6 ms achieved 92% specificity and 70% sensitivity in classifying children with and without Receptive LI. Auditory evoked responses appear to reflect language functioning and impairment rather than non-specific brain (dys)function (e.g., IQ, behavior). RH M50 latency proved to be a relatively useful indicator of impaired language comprehension, suggesting that delayed auditory perceptual processing in the RH may be a key neural dysfunction underlying the overlap between subgroups of children with autism and SLI.

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From Behavioral, Perceptual, and Neural Alterations in Sensory and Multisensory Function in Autism Spectrum Disorder (2015) · cites this paper as Cardy et al., 2008
Other studies have shown the opposite pattern of AEP latencies in ASD.
“others have shown the opposite pattern (Bruneau et al., 2003; Cardy et al., 2008)”
From Behavioral, Perceptual, and Neural Alterations in Sensory and Multisensory Function in Autism Spectrum Disorder (2015) · cites this paper as Cardy et al., 2008

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Authors: Oram Cardy, J. E., Flagg, E. J., Roberts, W., & Roberts, T. P. L.
Affiliations: York University (CA)
University of Toronto (CA)
Children's Hospital of Philadelphia (US)
ORCID: Roberts, Timothy P.L.
Venue: International Journal of Psychophysiology
Publisher: Elsevier BV
Published: 2008-05
Volume: 68
Issue: 2
Pages: 170-175
ISSN: 0167-8760 (ISSN-L)
DOI: 10.1016/j.ijpsycho.2007.10.015
OpenAlex: W2009824095
Cited by: 115
References: 42
Citations by year: 2026: 6 · 2025: 1 · 2024: 5 · 2023: 5 · 2022: 5 · 2021: 7 · 2020: 5 · 2019: 8 · 2018: 8 · 2017: 10 · 2016: 7 · 2015: 6 · 2014: 5 · 2013: 7 · 2012: 11
FWCI: 10.54
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: International Journal of Psychophysiology (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Developmental and Educational Psychology › Language Development and Disorders
Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Keywords: auditory evoked magnetic fields, language impairment, autism spectrum disorder, Asperger syndrome, specific language impairment, receptive language impairment, language comprehension, nonverbal intelligence, children and adolescents
MeSH terms: Acoustic Stimulation, Adolescent, Auditory Pathways, Auditory Perception, Autistic Disorder, Cerebral Cortex, Child, Discrimination, Psychological, Evoked Potentials, Auditory, Female, Humans, Language Development Disorders, Language Disorders, Functional Laterality, Male, Reference Values, ROC Curve, Magnetoencephalography, Case-Control Studies

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Auditory evoked fields predict language ability and impairment in children

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