Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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Interleukin-10 and the Interleukin-10 Receptor

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Interleukin-10-deficient mice develop chronic enterocolitis

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

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Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

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A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells

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Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

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Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells

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Dynamic changes in the regulatory T-cell heterogeneity and function by murine IL-2 mutein

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Physiological Functions of Mcl-1: Insights From Genetic Mouse Models

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Prostaglandin E 2 directly inhibits the conversion of inducible regulatory T cells through EP2 and EP4 receptors via antagonizing TGF‐β signalling

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CD103 integrin identifies a high IL‐10‐producing FoxP3 + regulatory T‐cell population suppressing allergic airway inflammation

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Vps33B controls Treg cell suppressive function through inhibiting lysosomal nutrient sensing complex-mediated mTORC1 activation

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B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation

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Resveratrol reduces lactate production and modifies the ovarian cancer immune microenvironment

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ICOS costimulation is indispensable for the differentiation of T follicular regulatory cells

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Exploring cell-based tolerance strategies for hand and face transplantation

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Regulatory T-Cell Differentiation and Their Function in Immune Regulation

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The miR-17∼92a Cluster of MicroRNAs Is Required for the Fitness of Foxp3+ Regulatory T Cells

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Inhibition of Lung Metastasis by Chemokine CCL17-mediated In Vivo Silencing of Genes in CCR4+ Tregs

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Enhancement of Mast Cell IL-6 Production by Combined Toll-Like and Nucleotide-Binding Oligomerization Domain-Like Receptor Activation

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Wnt/β-Catenin Signaling Induces Integrin α4β1 in T Cells and Promotes a Progressive Neuroinflammatory Disease in Mice

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Prolonged IKKβ Inhibition Improves Ongoing CTL Antitumor Responses by Incapacitating Regulatory T Cells

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Estrogen Signaling in Bystander Foxp3neg CD4+ T Cells Suppresses Cognate Th17 Differentiation in Trans and Protects from Central Nervous System Autoimmunity

Garnier, L., Laffont, S., Lélu, K., Yogev, N., Waisman, A., & Guéry, J. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1800417 · Cited by 24

Maf deficiency in T cells dysregulates Treg - TH17 balance leading to spontaneous colitis

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Increased oxidative stress and the apoptosis of regulatory T cells in obese mice but not resistant mice in response to a high-fat diet

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Control of IFN-γ production and regulatory function by the inducible nuclear protein IκB-ζ in T cells

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The Amphiregulin/EGFR axis protects from lupus nephritis via downregulation of pathogenic CD4+ T helper cell responses

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Regulation of Treg Cell Metabolism and Function in Non-Lymphoid Tissues

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The multifunctional human ocular melanocortin system

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The Indoleamine 2,3-dioxygenase Inhibitor 1-methyl-tryptophan Suppresses Mitochondrial Function, Induces Aerobic Glycolysis and Decreases Interleukin-10 Production in Human Lymphocytes

Eleftheriadis, T., Pissas, G., Karioti, A., Antoniadi, G., Liakopoulos, V., Dafopoulou, K., Pournaras, S., KOUKOULIS, G. N., & Stefanidis, I. (2012) · Immunological Investigations · doi:10.3109/08820139.2012.682244 · Cited by 22

Interleukin-37 Enhances the Suppressive Activity of Naturally Occurring CD4+CD25+ Regulatory T Cells

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Bcl11b prevents catastrophic autoimmunity by controlling multiple aspects of a regulatory T cell gene expression program

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CD226 deficiency on regulatory T cells aggravates renal fibrosis via up‐regulation of Th2 cytokines through miR‐340

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The link “Cancer and autoimmune diseases” in the light of microbiota: Evidence of a potential culprit

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Relevance of Commensal Microbiota in the Treatment and Prevention of Inflammatory Bowel Disease

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Interleukin‐2 critically regulates bone marrow erythropoiesis and prevents anemia development

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Janus kinases in inflammatory bowel disease: Four kinases for multiple purposes

Galien, R. (2016) · Pharmacological Reports · doi:10.1016/j.pharep.2016.04.001 · Cited by 22

The amalgam of naive CD4+ T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response

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The dual role of tissue regulatory T cells in tissue repair: return to homeostasis or fibrosis

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Effects of arsenic disulfide on proliferation, cytokine production, and frequencies of CD4 + , CD8 + , and regulatory T cells in mitogen-activated human peripheral blood mononuclear cells

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Aronia berry (Aronia mitschurinii ‘Viking’) inhibits colitis in mice and inhibits T cell tumour necrosis factor-α secretion

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Interleukin-10 mediated immune regulation after stem cell transplantation: Mechanisms and implications for therapeutic intervention

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Adenomatous Polyposis Coli Modulates Actin and Microtubule Cytoskeleton at the Immunological Synapse to Tune CTL Functions

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TIGIT agonism alleviates costimulation blockade-resistant rejection in a regulatory T cell–dependent manner

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Engineering nanoparticle therapeutics for food allergy

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Nuclear matrix protein SMAR1 control regulatory T-cell fate during inflammatory bowel disease (IBD)

Mirlekar, B., Ghorai, S., Khetmalas, M. B., Bopanna, R., & Chattopadhyay, S. (2015) · Mucosal Immunology · doi:10.1038/mi.2015.42 · Cited by 21

Dexmedetomidine ameliorates TNBS-induced colitis by inducing immunomodulator effect

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Differential T Cell Cytokine Receptivity and Not Signal Quality Distinguishes IL-6 and IL-10 Signaling during Th17 Differentiation

Jones, L. L., Alli, R., Li, B., & Geiger, T. L. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1402953 · Cited by 23

Treg Cells As Potential Cellular Targets for Functionalized Nanoparticles in Cancer Therapy

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FOXP3+ regulatory T cell ameliorates microvasculature in the rejection of mouse orthotopic tracheal transplants

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Neuropilin-1 Expression on CD4 T Cells Is Atherogenic and Facilitates T Cell Migration to the Aorta in Atherosclerosis

Gaddis, D. E., Padgett, L. E., Wu, R., & Hedrick, C. C. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1900245 · Cited by 21

CELL THERAPY IN INFLAMMATORY BOWEL DISEASE

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Intestinal immunoregulation: lessons from human mendelian diseases

Charbit‐Henrion, F., Parlato, M., Malamut, G., Ruemmele, F. M., & Cerf–Bensussan, N. (2021) · Mucosal Immunology · doi:10.1038/s41385-021-00398-3 · Cited by 23

Regulation of Effector Treg Cells in Murine Lupus

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The Gut's Clostridium Cocktail

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Targeting p97–Npl4 interaction inhibits tumor Treg cell development to enhance tumor immunity

Nie, P., Cao, Z., Yu, R., Dong, C., Zhang, W., Meng, Y., Zhang, H., Pan, Y., Tong, Z., Jiang, X., et al. (2024) · Nature Immunology · doi:10.1038/s41590-024-01912-y · Cited by 22

Therapeutic Potential of Polyphenols in Targeting Th17/Treg Balance for Intestinal Barrier Maintenance

Fu, J., Zhao, Z., Zhou, D., & Liu, S. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70400 · Cited by 23

Regulatory T Cells in the Immunodiagnosis and Outcome of Kidney Allograft Rejection

Franzese, O., Mascali, A., Capria, A., Castagnola, V., Paganizza, L., & Daniele, N. D. (2013) · Clinical and Developmental Immunology · doi:10.1155/2013/852395 · Cited by 20

CD4+CD126low/− Foxp3+ Cell Population Represents a Superior Subset of Regulatory T Cells in Treating Autoimmune Diseases

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IL-33 is produced by colon fibroblasts and differentially regulated in acute and chronic murine colitis

Waddell, A., Vallance, J. E., Fox, S. R., & Rosen, M. J. (2021) · Scientific Reports · doi:10.1038/s41598-021-89119-1 · Cited by 20

Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa

Stienne, C., Virgen‐Slane, R., Elmeń, L., Veny, M., Huang, S. X. L., Nguyen, J., Chappell, E., Balmert, M. O., Shui, J., Hurchla, M. A., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110553 · Cited by 20

Myc inhibition tips the immune balance to promote antitumor immunity

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Novel Phocaeicola Strain Ameliorates Dextran Sulfate Sodium-induced Colitis in Mice

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Germinal center B cells that acquire nuclear proteins are specifically suppressed by follicular regulatory T cells

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HSF1 promotes CD69+ Treg differentiation to inhibit colitis progression

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Influenza matrix 1‐specific human CD4+FOXP3+ and FOXP3− regulatory T cells can be detected long after viral clearance

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Epstein-Barr virus-induced gene 3-deficiency leads to impaired antitumor T-cell responses and accelerated tumor growth

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Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells

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NK Cell and CD4+FoxP3+ Regulatory T Cell Based Therapies for Hematopoietic Stem Cell Engraftment

Pierini, A., Álvarez, M., & Negrin, R. S. (2016) · Stem Cells International · doi:10.1155/2016/9025835 · Cited by 20

Control of Regulatory T Cell Differentiation by the Transcription Factors Thpok and LRF

Carpenter, A. C., Wohlfert, E., Chopp, L. B., Vacchio, M. S., Nie, J., Zhao, Y., Shetty, J., Xiao, Q., Deng, C., Tran, B. Q., et al. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1700181 · Cited by 21

Ectopic germline recombination activity of the widely used Foxp3‐YFP‐Cre mouse: a case report

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Toxoplasma gondii Oral Infection Induces Intestinal Inflammation and Retinochoroiditis in Mice Genetically Selected for Immune Oral Tolerance Resistance

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In Situ Patrolling of Regulatory T Cells Is Essential for Protecting Autoimmune Exocrinopathy

Ishimaru, N., Nitta, T., Arakaki, R., Yamada, A., Lipp, M., Takahama, Y., & Hayashi, Y. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008588 · Cited by 21

The Biology of Autoimmune Response in the Scurfy Mice that Lack the CD4+Foxp3+ Regulatory T-Cells

Ju, S., Sharma, R., Gaskin, F., Kung, J. T., & Fu, S. M. (2012) · Biology · doi:10.3390/biology1010018 · Cited by 20

Foxp3 as a marker of tolerance induction versus rejection

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Induction of Immune Tolerance to Dietary Antigens

Kim, K. S., & Surh, C. D. (2015) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-15774-0_8 · Cited by 19

Immune tolerance: Are regulatory T cell subsets needed to explain suppression of autoimmunity?

Tian, L., Humblet‐Baron, S., & Liston, A. (2012) · BioEssays · doi:10.1002/bies.201100180 · Cited by 20

Regulatory T Cell Modulation of Cytokine and Cellular Networks in Corneal Graft Rejection

Tahvildari, M., Inomata, T., Amouzegar, A., & Dana, R. (2018) · Current Ophthalmology Reports · doi:10.1007/s40135-018-0191-2 · Cited by 19

Moving to the Outskirts: Interplay Between Regulatory T Cells and Peripheral Tissues

Brull, A. E., Panetti, C., & Joller, N. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.864628 · Cited by 20

The Ameliorative Role of Probiotics in 5-fluorouracil Induced Intestinal Mucositis

Sim, A. A. X. H., Cheam, J. Y., Law, J. W., Letchumanan, V., Kumari, Y., Ogawa, S., Wong, S. H., Chan, K., & Tan, L. T. (2023) · Progress In Microbes & Molecular Biology · doi:10.36877/pmmb.a0000339 · Cited by 20

IL-2Rβ–Dependent Signaling and CD103 Functionally Cooperate To Maintain Tolerance in the Gut Mucosa

Yuan, X., Dee, M. J., Altman, N. H., & Malek, T. R. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1400955 · Cited by 21

Chemical Attenuation of Plasmodium in the Liver Modulates Severe Malaria Disease Progression

Lewis, M. D., Behrends, J., Cunha, C. S. E., Mendes, A. M., Lasitschka, F., Sattler, J. M., Heiß, K., Kooij, T. W. A., Prudêncio, M., Bringmann, G., et al. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1400863 · Cited by 19

Sequential Induction of Effector Function, Tissue Migration and Cell Death during Polyclonal Activation of Mouse Regulatory T-Cells

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