Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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Interleukin-10 and the Interleukin-10 Receptor

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Interleukin-10-deficient mice develop chronic enterocolitis

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

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Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

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A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells

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Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

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Current developments with peptide-based human tumor vaccines

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Induction of porcine reproductive and respiratory syndrome virus (PRRSV)-specific regulatory T lymphocytes (Treg) in the lungs and tracheobronchial lymph nodes of PRRSV-infected pigs

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A Stk4-Foxp3–NF-κB p65 transcriptional complex promotes T reg cell activation and homeostasis

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An integrated transcription factor framework for Treg identity and diversity

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Hyperactivating EZH2 to augment H3K27me3 levels in regulatory T cells enhances immune suppression by driving early effector differentiation

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Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis

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Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection

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CD45RA–Foxp3high activated/effector regulatory T cells in the CCR7+CD45RA–CD27+CD28+central memory subset are decreased in peripheral blood from patients with rheumatoid arthritis

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Transplant Games Promote Donation, Showcase Healthy Recipients

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BATF Regulates T Regulatory Cell Functional Specification and Fitness of Triglyceride Metabolism in Restraining Allergic Responses

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Regulatory T-Cell Therapy in Liver Transplantation and Chronic Liver Disease

Hann, A., Oo, Y. H., & Perera, M. T. P. R. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.719954 · Cited by 31

Network Pharmacology and Molecular Docking Analysis on Molecular Mechanism of Qingzi Zhitong Decoction in the Treatment of Ulcerative Colitis

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Epstein–Barr Virus Modulates Host Cell MicroRNA-194 to Promote IL-10 Production and B Lymphoma Cell Survival

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Apoptosis and Engulfment by Bronchial Epithelial Cells. Implications for Allergic Airway Inflammation

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Notch ligand Delta-like 4 induces epigenetic regulation of Treg cell differentiation and function in viral infection

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Immune regulation and anti-cancer activity by lipid inflammatory mediators

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Reprogramming alternative macrophage polarization by GATM-mediated endogenous creatine synthesis: A potential target for HDM-induced asthma treatment

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T cell control of inflammaging

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Dysregulation of T cell response in the pathogenesis of inflammatory bowel disease

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Terminal differentiation and persistence of effector regulatory T cells essential for preventing intestinal inflammation

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Nematode modulation of inflammatory bowel disease

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Transcriptional regulation of Treg homeostasis and functional specification

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Unstable regulatory T cells, enriched for naïve and Nrp1negcells, are purged after fate challenge

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Role of CD4+CD25+FOXP3+TRegcells on tumor immunity

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Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria

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Profiling of Tregs across tissues reveals plasticity in ST2 expression and hierarchies in tissue-specific phenotypes

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IFN-γ-Dependent Recruitment of CD4 + T Cells and Macrophages Contributes to Pathogenesis During Leishmania amazonensis Infection

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IFNγ Signaling Endows DCs with the Capacity to Control Type I Inflammation during Parasitic Infection through Promoting T-bet+ Regulatory T Cells

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Intestinal Immune Regulation as a Potential Diet-Modifiable Feature of Gut Inflammation and Autoimmunity

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Targeted Gene Panel Sequencing for Early-onset Inflammatory Bowel Disease and Chronic Diarrhea

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Next steps in regulatory T cells: Biology and clinical application

Zou, C., Li, P., Li, B., Sparwasser, T. D., & Yuan, J. (2026) · Cell · doi:10.1016/j.cell.2025.11.035 · Cited by 29

CD46-Induced Immunomodulatory CD4+ T Cells Express the Adhesion Molecule and Chemokine Receptor Pattern of Intestinal T Cells

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Long‐term tolerance to factor VIII is achieved by administration of interleukin‐2/interleukin‐2 monoclonal antibody complexes and low dosages of factor VIII

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T helper subsets & regulatory T cells: rethinking the paradigm in the clinical context of solid organ transplantation

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SHIP1 Deficiency in Inflammatory Bowel Disease Is Associated With Severe Crohn’s Disease and Peripheral T Cell Reduction

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Noc4L-Mediated Ribosome Biogenesis Controls Activation of Regulatory and Conventional T Cells

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Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation

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PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis

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Peroxisome Proliferator-Activated Receptor Alpha Mediates the Beneficial Effects of Atorvastatin in Experimental Colitis

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Negative Regulation of Type 2 Immunity

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Update on the Therapeutic Efficacy of Tregs in IBD

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Molecular feature and therapeutic perspectives of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome

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MrgprA3 neurons drive cutaneous immunity against helminths through selective control of myeloid-derived IL-33

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Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death

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Oral administration of Lactobacillus�plantarum 06CC2 prevents experimental colitis in mice via an anti‑inflammatory response

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Effect of Interleukin-36β on Activating Autophagy of CD4+CD25+ Regulatory T cells and Its Immune Regulation in Sepsis

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The demethylase inhibitor GSK-J4 limits inflammatory colitis by promoting de novo synthesis of retinoic acid in dendritic cells

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Lactoferrin Ameliorates Dry Eye Disease Potentially through Enhancement of Short-Chain Fatty Acid Production by Gut Microbiota in Mice

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The Acquired Immune System Response to Biomaterials, Including Both Naturally Occurring and Synthetic Biomaterials

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Novel Inhibitory Effect of a Lysophosphatidic Acid 2 Agonist on Allergen-Driven Airway Inflammation

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T-regulatory cells in primary immune deficiencies

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Opioid maintenance therapy restores CD4+ T cell function by normalizing CD4+CD25high regulatory T cell frequencies in heroin user

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Intratracheal transplantation of bone marrow‐derived mesenchymal stem cells reduced airway inflammation and up‐regulated CD 4+ CD 25+ regulatory T cells in asthmatic mouse

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CXCR6 + ST2 + memory T helper 2 cells induced the expression of major basic protein in eosinophils to reduce the fecundity of helminth

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Influences of non-IgE-mediated cow's milk protein allergy-associated gut microbial dysbiosis on regulatory T cell-mediated intestinal immune tolerance and homeostasis

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Therapeutic Strategies for Diabetes: Immune Modulation in Pancreatic β Cells

Jo, S., & Fang, S. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.716692 · Cited by 30

Therapeutic Potential of Regulatory T cells in Autoimmune Disorders

Fessler, J., Felber, A., Duftner, C., & Dejaco, C. (2013) · BioDrugs · doi:10.1007/s40259-013-0026-5 · Cited by 27

Tailoring gut immune responses with lipoteichoic acid-deficient Lactobacillus acidophilus

Lightfoot, Y. L., & Mohamadzadeh, M. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00025 · Cited by 27

Pathogenic T cell subsets in allergic and chronic inflammatory bowel disorders

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OX40L-expressing recombinant modified vaccinia virus Ankara induces potent antitumor immunity via reprogramming Tregs

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Genetic Contribution of CISH Promoter Polymorphisms to Susceptibility to Tuberculosis in Chinese Children

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High-Dimensional Mass Cytometric Analysis Reveals an Increase in Effector Regulatory T Cells as a Distinguishing Feature of Colorectal Tumors

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Heligmosomoides polygyrus bakeri Infection Decreases Smad7 Expression in Intestinal CD4+ T Cells, Which Allows TGF-β to Induce IL-10–Producing Regulatory T Cells That Block Colitis

Hang, L., Kumar, S., Blum, A. M., Urban, J. F., Fantini, M. C., & Weinstock, J. V. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1801392 · Cited by 25

Dynamic changes in the systemic immune responses of spinal cord injury model mice

Gao, T., Huang, F., Xie, Y., Wang, W.-Q., Wang, W., Mu, D., Cui, Y., & Wang, B. (2020) · Neural Regeneration Research · doi:10.4103/1673-5374.290910 · Cited by 28

Negative Immune Checkpoint Protein, VISTA, Regulates the CD4+ Treg Population During Sepsis Progression to Promote Acute Sepsis Recovery and Survival

Gray, C. C., Girard, B., Wakeley, M. E., Chung, C., Chen, Y., Quiles-Ramirez, Y., Tolbert, J. D., & Ayala, A. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.861670 · Cited by 25

A common IL‐4 receptor variant promotes asthma severity via a Treg cell GRB2‐IL‐6‐Notch4 circuit

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Dexmedetomidine alleviates acute lung injury by promoting Tregs differentiation via activation of AMPK/SIRT1 pathway

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Tissue-resident memory CD4 + T cells infiltrate the CNS in progressive multiple sclerosis and contribute to chronic autoimmunity in mice

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Enkephalin-producing regulatory T cells in the skin restrain local inflammation through control of nociception

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Convergences and Divergences of Thymus- and Peripherally Derived Regulatory T Cells in Cancer

Burocchi, A., Colombo, M. P., & Piconese, S. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00247 · Cited by 25

Tumor Tolerance–Promoting Function of Regulatory T Cells Is Optimized by CD28, but Strictly Dependent on Calcineurin

Marangoni, F., Zhang, R., Mani, V., Thelen, M., Akbar, N. J. A., Warner, R. D., Äijö, T., Zappulli, V., Martínez, G., Turka, L. A., et al. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1701220 · Cited by 24

Metformin alleviates experimental colitis in mice by up-regulating TGF-β signaling

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Regulatory T Cell Stability and Migration Are Dependent on mTOR

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The role of Treg subtypes in glomerulonephritis

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Layilin Anchors Regulatory T Cells in Skin

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