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Origins and Functional Specialization of Macrophages and of Conventional and Monocyte-Derived Dendritic Cells in Mouse Skin
Open accessAbstract
In the skin, the lack of markers permitting the unambiguous identification of macrophages and of conventional and monocyte-derived dendritic cells (DCs) complicates understanding of their contribution to skin integrity and to immune responses. By combining CD64 and CCR2 staining, we successfully identified each of these cell types and studied their origin, transcriptomic signatures, and migratory and T cell stimulatory properties. We also analyzed the impact of microbiota on their development and their contribution to skin inflammation during contact hypersensitivity. Dermal macrophages had a unique scavenging role and were unable to migrate and activate T cells. Conventional dermal DCs excelled both at migrating and activating T cells. In the steady-state dermis, monocyte-derived DCs are continuously generated by extravasated Ly-6C(hi) monocytes. Their T cell stimulatory capacity combined with their poor migratory ability made them particularly suited to activate skin-tropic T cells. Therefore, a high degree of functional specialization occurs among the mononuclear phagocytes of the skin.
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“Macrophages, largely monocyte-derived in a CCR2-dependent manner [34], contribute to microbial uptake and clearance, cytokine production, and tissue homeostasis.”
From Host–Candida auris interactions in the skin (2026) · cites this paper as [34]
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“Fibroblasts, though non-hematopoietic, also sense pathogens and secrete inflammatory mediators, highlighting the skin’s integrated immune-stromal cell network (see section below) [34–36].”
From Host–Candida auris interactions in the skin (2026) · cites this paper as [34]
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Cites
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., et al. (2010) · Science · doi:10.1126/science.1194637 · Cited by 5,175
T cell receptor antagonist peptides induce positive selection.
Hogquist, K., Jameson, S., Heath, W., Howard, J. L., Bevan, M., & Carbone, F. (1994) · Cell · doi:10.1016/0092-8674(94)90169-4 · Cited by 3,252
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
Schulz, C., Perdiguero, E. G., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S. E. W., Pollard, J. W., et al. (2012) · Science · doi:10.1126/science.1219179 · Cited by 2,578
Förster, R., Schubel, A., Breitfeld, D., Kremmer, E., Renner‐Müller, I., Wolf, E., & Lipp, M. (1999) · Cell · doi:10.1016/s0092-8674(00)80059-8 · Cited by 2,348
the Immunological Genome Consortium, Gautier, E. L., Shay, T., Miller, J., Greter, M., Jakubzick, C., Ivanov, S., Helft, J., Chow, A., Elpek, K. G., et al. (2012) · Nature Immunology · doi:10.1038/ni.2419 · Cited by 1,972
Serbina, N. V., & Pamer, E. G. (2006) · Nature Immunology · doi:10.1038/ni1309 · Cited by 1,658
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
Duffield, J. S., Forbes, S. J., Constandinou, C. M., Clay, S., Partolina, M., Vuthoori, S., Wu, S., Lang, R., & Iredale, J. P. (2005) · Journal of Clinical Investigation · doi:10.1172/jci200522675 · Cited by 1,649
Barnden, M., Allison, J., Heath, W. R., & Carbone, F. (1998) · Immunology and Cell Biology · doi:10.1046/j.1440-1711.1998.00709.x · Cited by 1,491
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
Kierdorf, K., Erny, D., Goldmann, T., Sander, V., Schulz, C., Perdiguero, E. G., Wieghofer, P., Heinrich, A., Riemke, P., Hölscher, C., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3318 · Cited by 1,457
Boring, L., Gosling, J., Chensue, S. W., Kunkel, S. L., Farese, R. V., Broxmeyer, H. E., & Charo, I. F. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119798 · Cited by 1,096
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Lamiable, O., Brewerton, M., & Ronchese, F. (2022) · European Journal of Immunology · doi:10.1002/eji.202149677 · Cited by 15
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Minarrieta, L., Ghorbani, P., Sparwasser, T. D., & Berod, L. (2016) · Seminars in Immunopathology · doi:10.1007/s00281-016-0609-6 · Cited by 15
Hain, T., Melchior, F., Kamenjarin, N., Muth, S., Weslati, H., Clausen, B. E., Mahnke, K., Silva-Vilches, C., Schütze, K., Sohl, J., et al. (2018) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2018.08.022 · Cited by 14
Joncker, N. T., Bettini, S., Boulet, D., Guiraud, M., & Guerder, S. (2015) · European Journal of Immunology · doi:10.1002/eji.201545797 · Cited by 19
Bourdely, P., Petti, L., Khou, S., Meghraoui, A., Elaldi, R., Cazareth, J., Mossadegh‐Keller, N., Boyer, J., Sieweke, M. H., Poissonnet, G., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.903069 · Cited by 13
Zeng, F., Wang, X., Hu, Y., Wang, Z., Li, Y., Hu, J., Yu, J., Zhou, P., Teng, X., Zhou, H., et al. (2023) · MedComm · doi:10.1002/mco2.229 · Cited by 13
Bosch, A. J. T., Rohm, T. V., AlAsfoor, S., Low, A. J. Y., Baumann, Z., Parayil, N., Noreen, F., Roux, J., Meier, D. T., & Cavelti‐Weder, C. (2023) · Particle and Fibre Toxicology · doi:10.1186/s12989-023-00536-8 · Cited by 15
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Bagirova, M., Allahverdiyev, A., Abamor, E. Ş., Ullah, I., Kutluoğlu, G. C., Aydoğdu, M. O., ŞENTÜRK, H., & Ergenoglu, B. (2016) · Parasite Immunology · doi:10.1111/pim.12360 · Cited by 13
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Abreu, C. M., Shirk, E. N., Queen, S. E., Mankowski, J. L., Gama, L., & Clements, J. E. (2018) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-018-9803-8 · Cited by 13
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Yang, Y., Hou, J., Liu, J., Bhushan, S., & Wu, G. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109047 · Cited by 14
Rahmberg, A. R., Wu, C., Shin, T., Hong, S. G., Pei, L., Markowitz, T. E., Hickman, H. D., Dunbar, C. E., & Brenchley, J. M. (2023) · Blood Advances · doi:10.1182/bloodadvances.2023011499 · Cited by 13
Isolation of Mouse Dendritic Cell Subsets and Macrophages from the Skin
Malosse, C., & Henri, S. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-3606-9_9 · Cited by 13
Self-citationThe impact of ischemia‐reperfusion injuries on skin resident murine dendritic cells
Goh, C. C., Evrard, M., Chong, S. Z., et al. (2018) · European Journal of Immunology · doi:10.1002/eji.201747347 · Cited by 13
Zhao, W., Zhao, G., Zhang, S., Wang, X., Yu, X., & Wang, B. (2018) · Oncotarget · doi:10.18632/oncotarget.25789 · Cited by 13
Functional Specialization of Dendritic Cell Subsets
Heidkamp, G. F., Lehmann, C. H. K., Heger, L., Baransk, A., Hoffmann, A., Lühr, J. J., & Dudziak, D. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-394447-4.30076-1 · Cited by 13
Lienard, J., Munke, K., Wulff, L., Silva, C. D., Vandamme, J., Laschanzky, K., Joeris, T., Agace, W. W., & Carlsson, F. (2023) · mBio · doi:10.1128/mbio.02764-22 · Cited by 13
Kim, M.-J., Ryu, H., Jeong, H. H., Van, J. Y., Hwang, J. Y., Kim, A.-R., Seo, J., Moon, K. M., Jung, W., & Lee, B. (2024) · Scientific Reports · doi:10.1038/s41598-024-62828-z · Cited by 14
Noviello, M., LORENZO, R. D., Chimienti, R., Maugeri, N., de Lalla, C., Siracusano, G., Lorè, N. I., Rancoita, P. M. V., Cugnata, F., Tassi, E., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1381091 · Cited by 13
SMAC mimetic drives microglia phenotype and glioblastoma immune microenvironment
Snacel-Fazy, E., Soubéran, A., Grange, M., Joseph, K., Colin, C., Morando, P., Luche, H., Pagano, A., Brustlein, S., Debarbieux, F. C., et al. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-07056-z · Cited by 13
Self-citationSustained accumulation of antigen‐presenting cells after infection promotes local T‐cell immunity
Collins, N., Hochheiser, K., Carbone, F. R., & Gebhardt, T. (2017) · Immunology and Cell Biology · doi:10.1038/icb.2017.60 · Cited by 12
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Tharmarajah, K., Everest‐Dass, A., Vider, J., Liu, X., Freitas, J. R., Mostafavi, H., Bettadapura, J., von Itzstein, M., West, N. P., Taylor, A., et al. (2022) · Journal of Virology · doi:10.1128/jvi.00999-22 · Cited by 13
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Wildner, P., & Selmaj, K. W. (2017) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2017.08.001 · Cited by 12
Singhal, R., Chawla, S., Batra, H., Gupta, S., Ojha, A., Rathore, D. K., Seth, T., & Guchhait, P. (2018) · European Journal of Immunology · doi:10.1002/eji.201747449 · Cited by 12
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Vollmers, A. C., Wu, S. Z., Altieri, A., McCartney, E. E., Bender, H. S., Davidson, C. D., Lee, W. P., Zhang, J., Hu, C., Jeet, S., et al. (2026) · Nature Immunology · doi:10.1038/s41590-026-02434-5 · Cited by 16
Metabolic adaption of mucosal macrophages: Is metabolism a driver of persistence across tissues?
Bennett, C. L., & Perona‐Wright, G. (2023) · Mucosal Immunology · doi:10.1016/j.mucimm.2023.06.006 · Cited by 11
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Yang, J., Zhang, L., Peng, X., Zhang, S., Sun, S., Ding, Q., Ding, C., & Liu, W. (2023) · Molecules · doi:10.3390/molecules28135066 · Cited by 11
Li, Y., Takaki, E., Ouchi, Y., & Tamai, K. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-024-05543-2 · Cited by 13
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Lößlein, A. K., & Henneke, P. (2025) · Annual Review of Immunology · doi:10.1146/annurev-immunol-082323-120757 · Cited by 14
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Alaoui, L., Villar, J., Leclère, R., Gallou, S. L., Relouzat, F., Michaud, H., Tarte, K., Teissier, N., Favier, B., Roussel, M., et al. (2023) · The Journal of Experimental Medicine · doi:10.1084/jem.20230002 · Cited by 11
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Ahlback, A., & Gentek, R. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3437-0_2 · Cited by 13
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Myakishev-Rempel, M., Stadler, I., Polesskaya, O., et al. (2015) · Photomedicine and Laser Surgery · doi:10.1089/pho.2015.3916 · Cited by 11
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Bain, C. C., & Jenkins, S. J. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7837-3_5 · Cited by 12
Yang, C. W., Ruiz‐Rosado, J. D. D., Robledo-Avila, F. H., et al. (2020) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2020.09.001 · Cited by 11
Simon, T., Pogu, J., Remy, S., Brau, F., Pogu, S., Maquigneau, M., Fonteneau, J., Poirier, N., Vanhove, B., Blancho, G., et al. (2017) · Journal of Autoimmunity · doi:10.1016/j.jaut.2017.03.005 · Cited by 11
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Gupta, A. (2021) · Springer eBooks · doi:10.1007/978-981-16-2677-7_1 · Cited by 13
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Gunawan, M., Jardine, L., & Haniffa, M. A. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-3606-9_8 · Cited by 10
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Gao, Y., Wang, J., Zhu, D., Miao, Y., & Hu, Z. (2021) · Molecular Immunology · doi:10.1016/j.molimm.2021.02.021 · Cited by 12
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Chopra, A., & Gupta, A. (2022) · Medicine in Novel Technology and Devices · doi:10.1016/j.medntd.2022.100196 · Cited by 10
Bi, X., Li, B., Zou, J., Zhao, J., Chen, Y., Wang, X., Lu, F., Li, Y., Dong, Z., & Gao, J. (2023) · Plastic & Reconstructive Surgery · doi:10.1097/prs.0000000000010259 · Cited by 10
Guilliams, M., & MALISSEN, B. (2016) · Immunity · doi:10.1016/j.immuni.2015.12.020 · Cited by 10
Self-citationOber-Blöbaum, J. L., Ortner, D., Haid, B., et al. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6786-5_3 · Cited by 10
Tian, T., Jin, M. Q., Dubin, K. A., King, S. L., Hoetzenecker, W., Murphy, G. F., Chen, C. A., Kupper, T. S., & Fuhlbrigge, R. C. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1500106 · Cited by 10
Fang, L., Chen, L., Bi, L., et al. (2020) · Immunological Investigations · doi:10.1080/08820139.2020.1781161 · Cited by 10
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Tabatabaei, N., Hou, S., Kim, K.-W., & Tahmasebi, S. (2020) · Cellular Signalling · doi:10.1016/j.cellsig.2020.109700 · Cited by 10
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Chong, S. Z., Evrard, M., Goh, C. C., & Ng, L. G. (2017) · Current Opinion in Immunology · doi:10.1016/j.coi.2017.12.004 · Cited by 10
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Porcuna, J., Menéndez-Gutierrez, M. P., & Ricote, M. (2020) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2020.04.001 · Cited by 10
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Raquer-McKay, H. M., Maqueda‐Alfaro, R. A., Saravanan, S., Hornero, R. A., Clausen, B. E., Gottfried‐Blackmore, A., & Idoyaga, J. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2404927121 · Cited by 8
Bashaw, A. A., Zhou, C., Yu, M., Tolley, L. K., Leggatt, G. R., Frazer, I. H., & Chandra, J. (2020) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2020.10.011 · Cited by 9
Macrophages and dendritic cells
Sutton, K., Balic, A., Kaspers, B., & Vervelde, L. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-818708-1.00003-8 · Cited by 9
Maz, M. P., Reddy, A. L., Berthier, C. C., Tsoi, L. C., Colesa, D. J., Wolf, S., Shi, H., Loftus, S. N., Moallemian, R., Wasikowski, R., et al. (2024) · Journal of Autoimmunity · doi:10.1016/j.jaut.2024.103296 · Cited by 8
Tintelnot, J., Ufer, F., Engler, J. B., Winkler, H., Lücke, K., Mittrücker, H., & Friese, M. A. (2019) · European Journal of Immunology · doi:10.1002/eji.201847797 · Cited by 7
Quiróz-González, S., Toro, A. O., Piceno, Y. G., et al. (2019) · Longhua Chinese Medicine · doi:10.21037/lcm.2019.12.01 · Cited by 8
Gross-Vered, M., Shmuel-Galia, L., Zarmi, B., Humphries, F., Thaiss, C. A., Salame, T., David, E., Chappell‐Maor, L., Fitzgerald, K. A., Shai, Y., et al. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1900470 · Cited by 8
Aghbash, P. S., Shirvaliloo, M., Kasho, A. K. A., Alinezhad, F., Nauwynck, H., & Baghi, H. B. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.108896 · Cited by 8
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Schiefermeier-Mach, N., Haller, T., Geley, S., & Perkhofer, S. (2020) · Pathogens · doi:10.3390/pathogens9120983 · Cited by 8
Tavernier, S. J., Lambrecht, B. N., & Janssens, S. (2017) · Current topics in microbiology and immunology · doi:10.1007/82_2017_1 · Cited by 6
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Murrey, M. W., Ng, I. T., & Pixley, F. J. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1480084 · Cited by 8
Greiner, D., Scott, T. M., Olson, G. S., Aderem, A. A., Roh‐Johnson, M., & Johnson, J. S. (2022) · Current Protocols · doi:10.1002/cpz1.514 · Cited by 7
Leone, D. A., Kozakowski, N., Kornauth, C., Waidacher, T., Neudert, B., Loeffler, A. G., Haitel, A., Rees, A. J., & Kain, R. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151674 · Cited by 7
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Lohrmann, F., Sankowski, R., Schwer, S., Neuber, J., Vlachou, E. P., Westermann, F., Troesch, E., Kolter, J., Loesslein, A. K., Mahapatra, K. D., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.09.631670 · Cited by 7
Heterogeneity of myeloid cells in common cancers: Single cell insights and targeting strategies
Jing, Z.-Q., Luo, Z.-Q., Chen, S.-R., & Sun, Z. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112253 · Cited by 7
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Cleene, H. K. L. D., Keçeli, B. N., & Maschalidi, S. (2025) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-92785-0_5 · Cited by 6
Pervizou, D., Chiara, J. D., Spinelli, L., NESTOR-MARTIN, M., Chasson, L., LEN-TAYON, K., Yanushko, D., FIORE, F., Bajénoff, M., Malissen, B., et al. (2025) · OncoImmunology · doi:10.1080/2162402x.2025.2562220 · Cited by 6
Self-citationSkin immunity and inflammation: cellular interactions and communication
Narayanan, D., Sim, S.-L., & Kumari, S. (2025) · Clinical & Translational Immunology · doi:10.1002/cti2.70053 · Cited by 10
PDGFRα‐lineage origin directs monocytes to trafficking proficiency to support peripheral immunity
Li, Y., Yamazaki, S., Takaki, E., Ouchi, Y., Kitayama, T., & Tamai, K. (2021) · European Journal of Immunology · doi:10.1002/eji.202149479 · Cited by 7
Majdoubi, A., Lee, J. S., Balood, M., Sabourin, A., DeMontigny, A., Kishta, O. A., Moulefera, M. A., Galbas, T., Yun, T. J., Talbot, S., et al. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1900593 · Cited by 6
Drevinge, C., Scheffler, J. M., Koro-Arvidsson, C., Sundh, D., Carlsten, H., Gjertsson, I., Lindholm, C., Lorentzon, M., Rudin, A., Ekwall, A. H., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0249205 · Cited by 6
Docq, M., Vétillard, M., Gallego, C., Jaracz‐Ros, A., Mercier‐Nomé, F., Bachelerie, F., & Schlecht‐Louf, G. (2021) · Cells · doi:10.3390/cells10113153 · Cited by 6
Tissue‐specific antigen‐presenting cells contribute to distinct phenotypes of allergy
Schülke, S., Gilles, S., Jirmo, A. C., & Mayer, J. U. (2023) · European Journal of Immunology · doi:10.1002/eji.202249980 · Cited by 6
Stellas, D., Karaliota, S., Stravokefalou, V., Angel, M., Nagy, B. A., Goldfarbmuren, K. C., Bergamaschi, C., Felber, B. K., & Pavlakis, G. N. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112501 · Cited by 8
Ravi, S., Martin, L. C., Krishnan, M., Kumaresan, M., Manikandan, B., & Ramar, M. (2023) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2023.105362 · Cited by 6
He, X., Li, H., Chen, Y., et al. (2016) · Inflammation · doi:10.1007/s10753-016-0341-3 · Cited by 6
Role of Dendritic Cells in Pathogen Infections: A Current Perspective
Muñoz‐Carrillo, J. L., Contreras‐Cordero, J. F., Gutiérrez‐Coronado, O., Villalobos‐Gutiérrez, P. T., Ramos-Gracia, L. G., & Vargas‐Barboza, J. M. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.95551 · Cited by 6
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McKarns, S. C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.64228-9 · Cited by 6
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Lian, M., Selmi, C. F., Gershwin, M. E., & Ma, X. (2018) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-017-8664-x · Cited by 6
Poised cell circuits in human skin are activated in diseasePreprint
Reynolds, G., Végh, P., Fletcher, J., Poyner, E. F. M., Stephenson, E., Goh, I., Botting, R. A., Huang, N., Olabi, B., Dubois, A., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.05.369363 · Cited by 7
Synovial Tissue Macrophage Heterogeneity in Rheumatoid Arthritis
Hanlon, M. M., Fearon, U., & Gravallese, E. M. (2026) · European Journal of Immunology · doi:10.1002/eji.70124 · Cited by 8
Steiger, L., Baumann, Z., Keller, L., et al. (2023) · STAR Protocols · doi:10.1016/j.xpro.2023.102664 · Cited by 5
Gingival monocytes: Lessons from other barriers
Wemyss, K., & Konkel, J. E. (2022) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2022.106194 · Cited by 5
Macrophage Development and Function
Makdissi, N. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3437-0_1 · Cited by 5
Molecular and cellular pruritus mechanisms in the host skin
Li, L., Li, Z.-E., Mo, Y.-L., Li, W.-Y., Li, H., Yan, G., Qin, X., & Piao, L. (2024) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2024.104889 · Cited by 7
Myeloid cells pave the way for lymphatic system development and maintenance
Ivanov, S., & Randolph, G. J. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1951-9 · Cited by 5
Interactions neuro-immunes dans la peau
Debroas, G., Hoeffel, G., Reynders, A., & Ugolini, S. (2018) · médecine/sciences · doi:10.1051/medsci/20183405016 · Cited by 7
Shakya, S., Asosingh, K., Mack, J. A., & Maytin, E. V. (2020) · MethodsX · doi:10.1016/j.mex.2020.101027 · Cited by 5
Non‐zero‐sum microbiome immune system interactions
Tuganbaev, T., & Honda, K. (2021) · European Journal of Immunology · doi:10.1002/eji.202049065 · Cited by 7
Developmental programming of macrophages by early life adversity
Pinto, M. M., Potter, H. G., Ahlback, A., & Gentek, R. (2022) · International review of cytology · doi:10.1016/bs.ircmb.2022.02.003 · Cited by 5
West, H. C., Davies, J., Henderson, S. R., Adegun, O. K., Ward, S., Ferrer, I. R., Tye, C. A., Vallejo, A. F., Jardine, L., Collin, M. P., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110819 · Cited by 5
Patel, A. A., & Yona, S. (2018) · Wiley eBooks · doi:10.1002/9780470015902.a0001218.pub2 · Cited by 6
Lai, G., Zhao, X., Chen, Y., Xie, T., Su, Z., Lin, J., Chen, K., & Chen, K. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114260 · Cited by 5
Dhariwala, M. O., Carale, R. O., DeRogatis, A. M., Rodriguez-Valbuena, H., Okoro, J. N., Ekstrand, C. A., Weckel, A., Tran, V. M., Habrylo, I., Barrere‐Cain, R., et al. (2026) · Immunity · doi:10.1016/j.immuni.2026.01.005 · Cited by 8
Transcription factor Etv3 controls the tolerogenic function of dendritic cells
Adams, N. M., Martinez-Krams, D., Esteva, E., Ra, A. C., Alexiou, A. I., Jin, H., Yun, T. J., Tellaoui, R. S., Mudianto, T., Vollmer, E., et al. (2026) · Science · doi:10.1126/science.ads1246 · Cited by 7
Trained immunity in skin infections: Macrophages and beyond
Gres, V., Göcer, M., Kolter, J., & Henneke, P. (2025) · eLife · doi:10.7554/elife.106688 · Cited by 7
Obesity alters the macrophages’ response to Leishmania major in C57BL/6 mice
Martins, V. D., Vaz, L. G., Barbosa, S. C., Paixão, P. H. D. M., Torres, L., de Oliveira, M. F. A., Oliveira, M. D. A., Vieira, L. Q., Faria, A. M. C., & Maioli, T. U. (2024) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiae171 · Cited by 4
Metadata
- Authors
- Tamoutounour, S., Guilliams, M., Montanana Sanchis, F., Liu, H., Terhorst, D., Malosse, C., Pollet, E., Ardouin, L., Luche, H., Sanchez, C., Dalod, M., Malissen, B., & Henri, S.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Malissen, Bernard
- Henri, Sandrine
- ORCID
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2013-11
- Volume
- 39
- Issue
- 5
- Pages
- 925-938
- ISSN
- 1074-7613 (ISSN-L)
- OpenAlex
- W2091487793
- Semantic Scholar
- 635234bed33c89ab8095a4fc56cfec78ea9dbe11
- Cited by
- 783
- References
- 25
- Citations by year
- 2026: 22 · 2025: 25 · 2024: 53 · 2023: 63 · 2022: 63 · 2021: 68 · 2020: 72 · 2019: 71 · 2018: 75 · 2017: 93 · 2016: 66 · 2015: 64 · 2014: 46
- FWCI
- 32.42
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Immunity (publishedVersion)
- PubMed (publishedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- Funders
- European Commission (223404)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Keywords
- dermal macrophages, myeloid dendritic cells, monocyte-derived dendritic cells, skin immune cells, monocyte origin, CD64, CCR2, Ly6C, T cell activation, dendritic cell migration, skin microbiome, contact hypersensitivity, skin inflammation, mononuclear phagocytes, gene expression signatures
- MeSH terms
- Animals, Antigens, Differentiation, Chemotaxis, Leukocyte, Chromatography, Gel, Dendritic Cells, Dermatitis, Contact, Langerhans Cells, Lymphocyte Cooperation, Macrophages, Monocytes, Radiation Chimera, Skin, Specific Pathogen-Free Organisms, Staining and Labeling, Immunophenotyping, Receptors, IgG, Gene Expression Regulation, Developmental, Cell Lineage, Dermis, Principal Component Analysis, CD11b Antigen, Mice, Receptors, CCR2, Transcriptome, Microbiota
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