The DOI matches its Crossref record; 67 of the 68 references it cites were found in a registry or an index.
Liver-Resident Macrophage Necroptosis Orchestrates Type 1 Microbicidal Inflammation and Type-2-Mediated Tissue Repair during Bacterial Infection
Open accessAbstract
Kupffer cells, the phagocytes of fetal origin that line the liver sinusoids, are key contributors of host defense against enteroinvasive bacteria. Here, we found that infection by Listeria monocytogenes induced the early necroptotic death of Kupffer cells, which was followed by monocyte recruitment and an anti-bacterial type 1 inflammatory response. Kupffer cell death also triggered a type 2 response that involved the hepatocyte-derived alarmin interleukin-33 (IL-33) and basophil-derived interleukin-4 (IL-4). This led to the alternative activation of the monocyte-derived macrophages recruited to the liver, which thereby replaced ablated Kupffer cells and restored liver homeostasis. Kupffer cell death is therefore a key signal orchestrating type 1 microbicidal inflammation and type-2-mediated liver repair upon infection. This indicates that beyond the classical dichotomy of type 1 and type 2 responses, these responses can develop sequentially in the context of a bacterial infection and act interdependently, orchestrating liver immune responses and return to homeostasis, respectively.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Basophils can activate fibroblasts in vitro and are an important source of IL-4 in inflammation, signaling to activate M2 macrophages [49].”
From Osteoimmunology of Fracture Healing. (2024) · cites this paper as [49]
In the citing paper
“In addition to competing for survival signals like CSF-1 (9, 33, 34), infiltrating monocytes actively replace embryonic KCs (EmKCs) during injury (35–37).”
From Macrophage duality in liver diseases: heterogeneity, plasticity, and the quest for precision therapeutics (2026) · cites this paper as [35]
Citations
Cites
Exploring the full spectrum of macrophage activation
Mosser, D. M., & Edwards, J. P. (2008) · Nature Reviews Immunology · doi:10.1038/nri2448 · Cited by 9,144
Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis
Yona, S., Kim, K.-W., Wolf, Y., Mildner, A., Varol, D., Breker, M., Strauss-Ayali, D., Viukov, S., Guilliams, M., Misharin, A., et al. (2013) · Immunity · doi:10.1016/j.immuni.2012.12.001 · Cited by 3,245
Development of T H 1 CD4 + T Cells Through IL-12 Produced by Listeria -Induced Macrophages
Hsieh, C.-S., Macatonia, S. E., Tripp, C. S., Wolf, S. F., O'Garra, A., & Murphy, K. M. (1993) · Science · doi:10.1126/science.8097338 · Cited by 3,134
Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., & Littman, D. R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.11.4106-4114.2000 · Cited by 2,632
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
Schulz, C., Perdiguero, E. G., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S. E. W., Pollard, J. W., et al. (2012) · Science · doi:10.1126/science.1219179 · Cited by 2,578
Hashimoto, D., Chow, A., Noizat, C., Teo, P., Beasley, M. B., Leboeuf, M., Becker, C. D., See, P., Price, J., Lucas, D., et al. (2013) · Immunity · doi:10.1016/j.immuni.2013.04.004 · Cited by 2,311 · cited 4×
“There are two main subtypes of F4/80 macrophages in mice, referred to as tissue-resident and monocyte-derived macrophages (Hashimoto et al., 2013; Schulz et al., 2012; Sieweke and Allen, 2013; Yona et al., 2013; Ginhoux and Jung, 2014).”
BackgroundInfluentialDavies, L. C., Jenkins, S. J., Allen, J. E., & Taylor, P. R. (2013) · Nature Immunology · doi:10.1038/ni.2705 · Cited by 2,096
Identification of RIP1 kinase as a specific cellular target of necrostatins
Degterev, A., Hitomi, J., Germscheid, M., Ch'en, I. L., Korkina, O., Teng, X., Abbott, D., Cuny, G. D., Yuan, C., Wagner, G., et al. (2008) · Nature Chemical Biology · doi:10.1038/nchembio.83 · Cited by 2,059
Arnold, L., Henry, A., Poron, F., Baba-Amer, Y., van Rooijen, N., Plonquet, A., Gherardi, R. K., & Chazaud, B. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20070075 · Cited by 2,002
Monitoring of Blood Vessels and Tissues by a Population of Monocytes with Patrolling Behavior
Auffray, C., Fogg, D., Garfa, M., Elain, G., Join-Lambert, O., Kayal, S., Sarnacki, S., Cumano, A., Lauvau, G., & Geissmann, F. (2007) · Science · doi:10.1126/science.1142883 · Cited by 1,973
Flagged first, then by citations
1 of the 68 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Pirie, 1927, A new disease of veld rodents. ‘Tiger River Disease’, Publ S Afr Inst Med Res, 3, 163
Cited by
Sorted by citations
Items 301–400 of 471
Chang, H., Ni, Y., Shen, C., Li, C., He, K., Zhu, X., Chen, L., Chen, L., Qiu, J., Ji, Y., et al. (2022) · Immunology · doi:10.1111/imm.13519 · Cited by 12
Han, D., Ma, Q., Ballar, P., Zhang, C., Dai, M., Luo, X., Gu, J. Y., Wei, C., Guo, P., Zeng, L., et al. (2024) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2024.05.001 · Cited by 12
Tang, J., Song, H., Li, S., Lam, S. M., Ping, J., Yang, M., Li, N., Chang, T., Yu, Z., Liu, W., et al. (2024) · Advanced Science · doi:10.1002/advs.202402693 · Cited by 12
Inhibition of neutrophil swarming by type I interferon promotes intracellular bacterial evasion
Li, S., Yao, Q., Li, J., Yang, H., Qian, R., Zheng, M., Wu, N., Jiang, H., Li, L., & Zeng, Z. (2024) · Nature Communications · doi:10.1038/s41467-024-53060-4 · Cited by 15
Yong, L., Li, M., Gao, Y., Deng, Y., Liu, W., Huang, D., Ren, C., Liu, M., Shen, J., & Hou, X. (2017) · Scientific Reports · doi:10.1038/srep46765 · Cited by 12
Simpson, J., Lynch, J. P., Loh, Z., Zhang, V., Werder, R. B., Spann, K. M., & Phipps, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-02564-9 · Cited by 13
Tissue Unit-ed: Lung Cells Team up to Drive Alveolar Macrophage Development
Scott, C. L., & Guilliams, M. (2018) · Cell · doi:10.1016/j.cell.2018.10.031 · Cited by 12
Germanova, D., Keirsse, J., Köhler, A., Hastir, J., Demetter, P., Delbauve, S., Elkrim, Y., Verset, L., Larbanoix, L., Preyat, N., et al. (2020) · International Journal of Cancer · doi:10.1002/ijc.33334 · Cited by 12
Repopulating Kupffer cells originate directly from hematopoietic stem cells
Fan, X., Lu, P., Cui, X., Wu, P., Lin, W., Zhang, D., Yuan, S.-Z., Liu, B., Chen, F., You, H., et al. (2023) · Stem Cell Research & Therapy · doi:10.1186/s13287-023-03569-0 · Cited by 11
Research Progress on the Immune Function of Liver Sinusoidal Endothelial Cells in Sepsis
Wang, X., Guo, Z., Xia, Y., Wang, X., & Wang, Z. (2025) · Cells · doi:10.3390/cells14050373 · Cited by 12
Roles of heterogenous hepatic macrophages in the progression of liver diseases
Lee, K., Kim, M., & Han, Y. (2022) · BMB Reports · doi:10.5483/bmbrep.2022.55.4.022 · Cited by 12
Fate-Mapping Macrophages: From Ontogeny to Functions
Ahlback, A., & Gentek, R. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3437-0_2 · Cited by 13
CXCR6+CD4+ T cells promote mortality during Trypanosoma brucei infection
Liu, G., Abas, O. M., Strickland, A. B., Chen, Y., & Shi, M. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1009968 · Cited by 11
Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic inflammation
Kessler, S. M., Hoppstädter, J., Hosseini, K., Laggai, S., Haybaeck, J., & Kiemer, A. K. (2019) · Journal of Hepatology · doi:10.1016/j.jhep.2018.11.018 · Cited by 11
Sanchez Vasquez, J. D., Nkongolo, S., Traum, D., Sotov, V., Kim, S. C., Mahamed, D., Mehrotra, A., Patel, A., Chen, D. Y., Fung, S., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci175241 · Cited by 11
Wang, B.-W., Yang, X., Zuo, X., Zeng, H., Wang, X., Huang, H.-X., He, D., Wang, L., Ouyang, H.-P., & Yuan, J. (2023) · American Journal of Pathology · doi:10.1016/j.ajpath.2023.04.004 · Cited by 9
Early ART reduces viral seeding and innate immunity in liver and lungs of SIV-infected macaques
Clain, J. A., Rabezanahary, H., Racine, G., Boutrais, S., Soundaramourty, C., Beauparlant, C. J., Jenabian, M.-A., Droit, A., Ancuța, P., Zghidi‐Abouzid, O., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.167856 · Cited by 11
Kupffer cells are essential for platelet-mediated thrombopoietin generation in the liver
Karakas, D., Li, J., Ma, W., Wu, X., Khoury, C. J., Masoud, M., Hoard, B., Liu, Y., Zhu, G., Chen, J., et al. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2517319122 · Cited by 10
Li, X., Wu, J., Zhu, S., Wei, Q., Wang, L., & Chen, J. (2023) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-023-04846-0 · Cited by 10
Zhao, D., Cai, C., Zheng, Q., Jin, S., Song, D., Shen, J., & Ran, Z. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.12.160 · Cited by 10
Tuning the way to die: implications of membrane perturbations in necroptosis
Espiritu, R. A., Pedrera, L., & Ros, U. (2019) · Advances in biomembranes and lipid self-assembly · doi:10.1016/bs.abl.2019.01.006 · Cited by 10
Li, T., Xie, Y., Shi, L., Sun, Y., Wen, J., Deng, Z., Zhang, H., Li, H., Yang, J., & Xiao, H. Q. (2021) · ImmunoHorizons · doi:10.4049/immunohorizons.2000093 · Cited by 11
Hastir, J., Delbauve, S., Larbanoix, L., Germanova, D., Goyvaerts, C., Allard, J., Laurent, S., Breckpot, K., Beschin, A., Guilliams, M., et al. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.547013 · Cited by 10
Interfering with Kupffer cell replenishment: New insights into liver injury
Alazawi, W., & Knolle, P. A. (2018) · Journal of Hepatology · doi:10.1016/j.jhep.2018.01.011 · Cited by 12
Injarabian, L., Willenborg, S., Welcker, D., Sanin, D. E., Pasparakis, M., Kashkar, H., & Eming, S. A. (2023) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2023.06.203 · Cited by 11
The ontogenesis and heterogeneity of basophils
Park, J., & Kang, S. (2024) · Discovery Immunology · doi:10.1093/discim/kyae003 · Cited by 10
Zhang, H., You, G., Yang, Q., Jin, G., Lv, G., Fan, L., Chen, Y., Li, H., Yi, S., Li, H., et al. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2024.167130 · Cited by 9
A historical perspective of Kupffer cells in the context of infection
Graham, C. T., Gordon, S., & Kubes, P. (2024) · Cell and Tissue Research · doi:10.1007/s00441-024-03924-4 · Cited by 10
Emerging roles of basophils in the resolution of acute respiratory distress syndrome
Takasawa, S., Tateishi, T., Sugihara, J., Shibata, S., Ito, J., Ito, M., Hata, K., Miyake, S., Karasuyama, H., Miyake, K., et al. (2025) · European Respiratory Journal · doi:10.1183/13993003.01150-2024 · Cited by 9
Liver Monocytes and Kupffer Cells Remain Transcriptionally Distinct during Chronic Viral Infection
van de Garde, M. D. B., Movita, D., van der Heide, M., Herschke, F., Jonghe, S. D., Gama, L., Boonstra, A., & Vanwolleghem, T. (2016) · PLoS ONE · doi:10.1371/journal.pone.0166094 · Cited by 9
Maternal- and Fetal-Encoded Perforin-2 Limits Placental Infection by a Bloodborne Pathogen
Gayle, P., McGaughey, V., Hernandez, R., Wylie, M. R., Colletti, R. C., Nguyen, K. L., Arons, M., Padula, L., Štrbo, N., & Schesser, K. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.2000615 · Cited by 9
Fukushima, H., Kono, H., Hirayama, K., Akazawa, Y., Nakata, Y., Wakana, H., & Fujii, H. (2020) · Clinical and Experimental Gastroenterology · doi:10.2147/ceg.s248635 · Cited by 9
Behind the monocyte’s mystique: uncovering their developmental trajectories and fates
Teh, Y. C., Chooi, M. Y., & Chong, S. Z. (2023) · Discovery Immunology · doi:10.1093/discim/kyad008 · Cited by 12
NK1.1+ cells promote sustained tissue injury and inflammation after trauma with hemorrhagic shock
Chen, S., Hoffman, R. A., Scott, M. J., Manson, J., Loughran, P., Ramadan, M., Demetris, A. J., & Billiar, T. R. (2017) · Journal of Leukocyte Biology · doi:10.1189/jlb.3a0716-333r · Cited by 9
The Role of Immune Cells in Liver Regeneration
Wen, Y. (2023) · Livers · doi:10.3390/livers3030029 · Cited by 8
Progression of Kidney Fibrosis after Sepsis
de Roquetaillade, C., Durand, M., Beaucoté, V., Guillemin, J., Chadjichristos, C. E., Roquilly, A., & Chousterman, B. G. (2025) · Journal of the American Society of Nephrology · doi:10.1681/asn.0000000712 · Cited by 10
Fasting-induced ketogenesis sensitizes bacteria to antibiotic treatment
Cui, S., Chong, D., Wang, Y., Tong, H., Wang, M., Zhao, G., & Lyu, L.-D. (2025) · Cell Metabolism · doi:10.1016/j.cmet.2025.04.006 · Cited by 7
Descoeudres, N., Jouneau, L., Henry, C., Gorrichon, K., Derré‐Bobillot, A., Serror, P., Gillespie, L. L., Archambaud, C., Pagliuso, A., & Bierne, H. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.761945 · Cited by 7
Qian, Z., Xiong, W., Mao, X., & Li, J. (2024) · Biomolecules · doi:10.3390/biom14060700 · Cited by 9
Hepatic macrophages in drug-induced liver injury
Shan, Z., & Ju, C. (2019) · Liver Research · doi:10.1016/j.livres.2019.11.002 · Cited by 7
Bénard, A., Podolska, M. J., Czubayko, F., Kutschick, I., Klösch, B., Jacobsen, A., Naschberger, E., Brunner, M., Krautz, C., Trufa, D. I., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.821480 · Cited by 7
Fauteux‐Daniel, S., Viel, S., Besson, L., Zhang, J., Marotel, M., Mathieu, A., Pescarmona, R., Charrier, E., Henry, T., Bélot, A., et al. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1701628 · Cited by 7
Inflammation drives age-induced loss of tissue resident macrophagesPreprint
Adé, K., Coronilla, J. S., Obino, D., Weinberger, T., Kaiser, C., Mella, S., Chen, C., Katsimpardi, L., Werts, C., Li, H., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.02.510513 · Cited by 7
Kuipery, A., Mahamed, D., Nkongolo, S., D’Angelo, J. A., Valiente, A. J., Mehrotra, A., Chapman, W. C., Horton, P. J., McGilvray, I. D., Janssen, H. L. A., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.818612 · Cited by 6
Sun, X., Ni, Y., Lu, Q., Liang, Y., Gu, M., Xue, X., & Dai, C. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05487-0 · Cited by 8
Cross-regulation of Listeria monocytogenes and the host ubiquitin system in listeriosis
Zhuang, Y., Fischer, J. B., Nishanth, G., & Schlüter, D. (2024) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2024.151401 · Cited by 6
Listeriosis downregulates hepatic cytochrome P450 enzymes in sublethal murine infection
Kummer, A., Nishanth, G., Koschel, J., Klawonn, F., Schlüter, D., & Jänsch, L. (2016) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.201600030 · Cited by 6
Myeloid Cells and Chronic Liver Disease: a Comprehensive Review
Lian, M., Selmi, C. F., Gershwin, M. E., & Ma, X. (2018) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-017-8664-x · Cited by 6
RIPK1, a key survival factor for hepatocytes
Blériot, C., & Lecuit, M. (2017) · Journal of Hepatology · doi:10.1016/j.jhep.2017.02.009 · Cited by 6
Self-citationWang, Z., Liang, G., Peng, J., Gu, Y., Zhang, X., Ding, C., Yu, T., & Li, Z. (2024) · American Journal Of Pathology · doi:10.1016/j.ajpath.2024.12.006 · Cited by 5
Bobadilla, R., MacLean, F., Dave, S., Blackard, J. T., & Gianella, S. (2026) · Infection and Drug Resistance · doi:10.2147/idr.s576715 · Cited by 5
Fatty acid synthesis is indispensable for Kupffer cells to eliminate bacteria in ALD progression
Xie, L., Wu, B., Fan, Y., Tao, Y., Jiang, X., Li, Q., Zhu, H., Wang, H., & Hu, C. (2024) · Hepatology Communications · doi:10.1097/hc9.0000000000000522 · Cited by 5
Necroptosis in apical periodontitis: A programmed cell death with multiple roles
Liu, H., Fan, W., & Fan, B. (2023) · Journal of Cellular Physiology · doi:10.1002/jcp.31073 · Cited by 5
Park, Y. H., Lee, S. W., Kim, T.-C., Park, H. J., Kaer, L. V., & Hong, S. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1457690 · Cited by 5
Volmari, A., Foelsch, K., Zierz, E., Yan, I., Qi, M., Bartels, K., Kondratowicz, S., Böttcher, M., Reimers, D., Nishibori, M., et al. (2021) · Hepatology Communications · doi:10.1002/hep4.1777 · Cited by 5
Gres, V., Lohrmann, F., Fuchs, V., Neuber, J., Moghadam, Z. M., Lößlein, A. K., Bosch, L. F. P., Figueiral-Martins, T., Baasch, S., Obwegs, D., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.02.27.582183 · Cited by 5
Role of Immune Cells in Hepatitis B Virus and Associated Sequelae
Lin, J., & Gehring, A. J. (2025) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-042524-030646 · Cited by 5
Macrophage polarization in organ transplantation rejection and targeted therapeutic strategies
Qu, C., Chen, Y., Xu, X., Li, X., Chen, D., Du, W., Zhang, M., Yang, Z., & Wang, J. (2025) · Transplant Immunology · doi:10.1016/j.trim.2025.102316 · Cited by 5
Cellular effects of splenectomy on liver regeneration after 70% resection
Elchaninov, A. V., Vishnyakova, P., Gantsova, E. A., Chirkova, M., Karyagina, V., Anatoliy, L., Kananykhina, E. Y., Kuznetsova, M., Atabekov, I., Karpulevich, E., et al. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1561815 · Cited by 4
Hossen, M. J., Matin, M. A., Sikder, M. H., Ahmed, M. S., & Rahman, M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822368-0.00016-5 · Cited by 4
Reply to: “Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic inflammation”
Borst, K., Graalmann, T., & Kalinke, U. (2019) · Journal of Hepatology · doi:10.1016/j.jhep.2018.12.034 · Cited by 4
Zhu, Y., Liu, X., Guo, F., Qu, J., Liu, X., Xu, Q., Sheng, J., Wang, J., Xie, X., Ren, R., et al. (2025) · Advanced Science · doi:10.1002/advs.202512828 · Cited by 3
Adams, J., Li, T., Zhu, P., Garbe, C. G., Tu, F., Casteel, J. L., Yakubenko, V. P., Williams, D. L., Li, C., & Wang, X. (2025) · Immunology · doi:10.1111/imm.70043 · Cited by 3
STAT1 drives the immune landscape of murine Toll-like receptor 9-induced liver inflammation
Visscher, A. D., Beliën, J., Bernaerts, E., Vandeput, M., Malengier‐Devlies, B., Prenen, F., Meers, H., Sokol, L., Mitera, T., Berghmans, N., et al. (2025) · JHEP Reports · doi:10.1016/j.jhepr.2025.101668 · Cited by 3
Huang, G., & Li, D. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1751290 · Cited by 3
Kupffer cell plasticity regulates hepatic immunity in mycobacterial infection
Neuber, J., Lohrmann, F., Wald, S., Göcer, M., Lößlein, A. K., Obwegs, D., Rogg, M., Gres, V., Kolter, J., Goldmann, T., et al. (2026) · Journal of Hepatology · doi:10.1016/j.jhep.2026.02.024 · Cited by 3
Heterogeneity of bacterial host-pathogen interactions across biological scales
Redondo, J. A., Purkait, N., & Paszek, P. (2026) · mSystems · doi:10.1128/msystems.01804-25 · Cited by 3
Li, Q., Liang, F., Bhattarai, S., Divangahi, M., Kaufmann, E., & Petrof, B. J. (2024) · Scientific Reports · doi:10.1038/s41598-024-59527-0 · Cited by 3
With Respect to Macrophages, Judge the Liver by Its Cover
Zigmond, E., & Varol, C. (2017) · Immunity · doi:10.1016/j.immuni.2017.07.022 · Cited by 3
Innate and Adaptive Immune Responses duringListeria monocytogenesInfection
D’Orazio, S. E. F. (2019) · ASM Press eBooks · doi:10.1128/9781683670131.ch51 · Cited by 3
p38MAPK guards the integrity of endosomal compartments through regulating necrotic death
Yao, J., Atasheva, S., Toy, R., Blanchard, E. L., Santangelo, P. J., Roy, K., Mocarski, E. S., & Shayakhmetov, D. M. (2022) · Scientific Reports · doi:10.1038/s41598-022-20786-4 · Cited by 3
Xu, F. H., Jansakun, C., Li, G., Biswas, U., Poschet, G., Staffer, S., Tuma‐Kellner, S., Nakchbandi, I. A., Merle, U., & Chamulitrat, W. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118146 · Cited by 2
Immune cells in liver regeneration: Current evidence and potential clinical targets
Moore, H. F., Usmani, S., Froghi, S., Rashidi, H., Quaglia, A., Fuller, B. J., & Davidson, B. R. (2025) · International Reviews of Immunology · doi:10.1080/08830185.2025.2531820 · Cited by 4
Jadon, K., & Padhi, S. (2025) · Current Topics in Medicinal Chemistry · doi:10.2174/0115680266398364250811231140 · Cited by 4
Lynch, R. W., Louwe, P. A., Martens, L., Candela, M. E., Bain, C. C., Hawley, C. A., Henderson, N. C., Ramachandran, P., Bénézech, C., Scott, C. L., et al. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117136 · Cited by 3
Basophils drive the resolution and promote wound healing in adult and aged mice
Bex-Coudrat, J., Peter, V., Saji, C., Dupont, C., Lavernhe, M., Jin, S., Chapart, L., Gautier, G., Thibaudeau, O., Thaminy, M. K., et al. (2026) · The Journal of Experimental Medicine · doi:10.1084/jem.20240764 · Cited by 4
Sakai, M. (2022) · Diabetology International · doi:10.1007/s13340-022-00610-0 · Cited by 2
Tavares-Gomes, L., Polidori, M., Monney, C., Neuhaus, G., Vidondo, B., Witz, G., Hemphill, A. F., & Oevermann, A. (2025) · Acta Neuropathologica · doi:10.1007/s00401-025-02900-8 · Cited by 2
Using a Bacterial Pathogen to Probe for Cellular and Organismic-level Host Responses
Gayle, P., Freitag, N. E., Štrbo, N., & Schesser, K. (2019) · Journal of Visualized Experiments · doi:10.3791/58775 · Cited by 2
Akbari, M., Kimura, K., Houts, J. T., & Yui, K. (2016) · Parasitology International · doi:10.1016/j.parint.2016.02.011 · Cited by 2
Fan, X., Shan, S., Wu, P., Lin, W., Jia, J., & He, F. (2020) · Scandinavian Journal of Immunology · doi:10.1111/sji.12916 · Cited by 2
Murine Monocytes: Origins, Subsets, Fates, and Functions
Mildner, A., Marinković, G., & Jung, S. (2017) · ASM Press eBooks · doi:10.1128/9781555819194.ch9 · Cited by 2
Immune Functions of the M2 Macrophages: Host Defense, Self-tolerance, and Autoimmunity
Rőszer, T. (2020) · Progress in inflammation research · doi:10.1007/978-3-030-50480-9_6 · Cited by 2
Shalova, I. N., Saha, S., & Biswas, S. K. (2017) · Wiley-VCH eBooks · doi:10.1002/9783527692156.ch9 · Cited by 2
Basophils drive the resolution and promote wound healing in adult and aged micePreprint
Bex-Coudrat, J., Peter, V., Saji, C., Chapart, L., Jin, S., Gautier, G., Thibaudeau, O., Thaminy, M. K., Tchen, J., Simon, Q., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.02.601665 · Cited by 2
Chen, L., Chen, Y., Zhao, M., Yang, X., Sutte, K., Lu, M., Chen, J., Zheng, X., Yang, D., & Liu, J. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1814879 · Cited by 1
Acute bacterial and viral infections
Juanola, O., Caparrós, E., & Francés, R. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95262-0.00011-5 · Cited by 1
Jiao, J., Ma, Z., Li, N., Duan, F., Cai, X., Zuo, Y., Li, J., Meng, Q., & Qiao, J. (2025) · Microorganisms · doi:10.3390/microorganisms13020410 · Cited by 1
Unveiling the Role of Sdc4 + Monocytes in NASH: A Single-Cell RNA Sequencing Study
Li, J.-Z., Mao, T., Gao, Y.-X., Xu, M., & Li, H. (2025) · Immunological Investigations · doi:10.1080/08820139.2025.2544180 · Cited by 1
Th1 and Th2 cells in equine endometrosis and their interactions with endometrial fibroblasts
Wójtowicz, A., Sadowska, A., Molcan, T., Słyszewska, M., Drzewiecka, E. M., Tobolski, D., Ferreira-Dias, G. M., & Szóstek-Mioduchowska, A. Z. (2025) · Scientific Reports · doi:10.1038/s41598-025-20152-0 · Cited by 1
Miller, S. J., Janssen, R. C., Zhao, W., Jonscher, K. R., Zhong, H., DeVette, C. I., Friedman, J. E., & Zimmerman, K. A. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1698609 · Cited by 1
Bacterial infection reshapes monocyte and macrophage ontogeny at the CNS borders
Gres, V., Lohrmann, F., Fuchs, V., Neuber, J., Moghadam, Z. M., Lößlein, A. K., Bosch, L. F. P., Figueiral-Martins, T., Baasch, S., Obwegs, D., et al. (2026) · Science Immunology · doi:10.1126/sciimmunol.aee9584 · Cited by 6
The Switch: Mechanisms Governing Macrophage Phenotypic Variability in Liver Disease
Marentette, J., & Ju, C. (2017) · Springer eBooks · doi:10.1007/978-3-319-58106-4_4 · Cited by 1
Nuclear DAMPs in Hepatic Injury and Inflammation
Kang, R., & Tang, D. (2017) · Springer eBooks · doi:10.1007/978-3-319-58106-4_7 · Cited by 1
Acid Aspiration Impairs Antibacterial Properties of Liver Macrophages
Langelage, M., Better, J., Wetstein, M., Selvakumar, B., Malainou, C., Kimmig, L. M., Arneth, B. M., Köhler, K., Herden, C., Herold, S., et al. (2021) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2020-0575le · Cited by 1
Role of macrophages in tumor development
Karim, M. R., Hossain, D., Uddin, A. M., & Rume, F. I. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822368-0.00007-4 · Cited by 2
Microglia cannibalism during neurodevelopment results in necroptotic cell death
Bennett, F. C., & Bennett, M. L. (2024) · PLoS Biology · doi:10.1371/journal.pbio.3002869 · Cited by 1
Pozdina, V. A., Зведенинова, У. В., Ulitko, M. V., Danilova, I. G., & Abidov, M. T. (2021) · Cell and Tissue Biology · doi:10.1134/s1990519x21060158 · Cited by 1
Recent Advances in the Detection of Listeria monocytogenes
Adhikari, P., Florien, N., Gupta, S., & Kaushal, A. (2023) · Infectious diseases · doi:10.5772/intechopen.109948 · Cited by 2
Raynes, J. G. (2015) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0000497.pub2 · Cited by 1
Metadata
- Authors
- Blériot, C., Dupuis, T., Jouvion, G., Eberl, G., Disson, O., & Lecuit, M.
- Affiliations
- Inserm (FR)
- Institut Pasteur (FR)
- Hôpital Necker-Enfants Malades (FR)
- Corresponding author
- Lecuit, Marc
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2015-01
- Volume
- 42
- Issue
- 1
- Pages
- 145-158
- ISSN
- 1074-7613 (ISSN-L)
- OpenAlex
- W2082812721
- Cited by
- 471
- References
- 68
- Citations by year
- 2026: 24 · 2025: 35 · 2024: 45 · 2023: 41 · 2022: 42 · 2021: 57 · 2020: 42 · 2019: 35 · 2018: 47 · 2017: 42 · 2016: 41 · 2015: 20
- FWCI
- 15.67
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Immunity (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- Agence Nationale de la Recherche (ANR-10-LABX-0062)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Life Sciences › Immunology and Microbiology › Immunology › IL-33, ST2, and ILC Pathways
- Keywords
- Kupffer cells, necroptosis, Listeria monocytogenes, liver infection, type 1 inflammation, Th2 immune response, IL-33, IL-4, monocyte recruitment, alternative activation, tissue repair, liver homeostasis, hepatic macrophages
- MeSH terms
- Interleukin-33, Animals, Cell Differentiation, Cells, Cultured, Complement Pathway, Alternative, Homeostasis, Inflammation, Interleukins, Kupffer Cells, Listeriosis, Listeria monocytogenes, Liver, Mice, Inbred Strains, Monocytes, Necrosis, Phagocytosis, Wound Healing, Interleukin-4, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review