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Cited by 559

The DOI matches its Crossref record; 166 of the 166 references it cites were found in a registry or an index.

Interferons and Proinflammatory Cytokines in Pregnancy and Fetal Development

Open access
Yockey, Laura J., Iwasaki, Akiko·2018·Immunity

Abstract

Successful pregnancy requires carefully-coordinated communications between the mother and fetus. Immune cells and cytokine signaling pathways participate as mediators of these communications to promote healthy pregnancy. At the same time, certain infections or inflammatory conditions in pregnant mothers cause severe disease and have detrimental impacts on the developing fetus. In this review, we examine evidence for the role of maternal and fetal immune responses affecting pregnancy and fetal development, both under homeostasis and following infection. We discuss immune responses that are necessary to promote healthy pregnancy and those that lead to congenital disorders and pregnancy complications, with a particular emphasis on the role of interferons and cytokines. Understanding the contributions of the immune system in pregnancy and fetal development provides important insights into the pathogenesis underlying maternal and fetal diseases and sheds insights on possible targets for therapy.

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Metadata

Authors
Yockey, L. J., & Iwasaki, A.
Venue
Immunity
Publisher
Elsevier BV
Published
2018-09
Volume
49
Issue
3
Pages
397-412
ISSN
1074-7613 (ISSN-L)
OpenAlex
W2890344556
Cited by
559
References
166
FWCI
12.47
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Interferons and Proinflammatory Cytokines in Pregnancy and Fetal Development. https://app.cochat.ai/papers/10.1016/j.immuni.2018.07.017
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Yockey, L. J., & Iwasaki, A. (2018). Interferons and Proinflammatory Cytokines in Pregnancy and Fetal Development. Immunity. https://doi.org/10.1016/j.immuni.2018.07.017

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.