Interferon-inducible antiviral effectors

Virus interference. I. the interferon

Isaacs, A., & Lindenmann, J. (1957) · Proceedings of the Royal Society of London. Series B - Biological Sciences · doi:10.1098/rspb.1957.0048 · Cited by 3,451 · see citing works

Functional Role of Type I and Type II Interferons in Antiviral Defense

Müller, U., Steinhoff, U., Reis, L. F. L., Hemmi, S., Pavlovic, J., Zinkernagel, R. M., & Aguet, M. (1994) · Science · doi:10.1126/science.8009221 · Cited by 2,453 · see citing works

Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays

Der, S. D., Zhou, A., Williams, B. R. G., & Silverman, R. H. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.26.15623 · Cited by 1,805 · see citing works

Interferons at age 50: past, current and future impact on biomedicine

Borden, E. C., Sen, G. C., Uze, G., Silverman, R. H., Ransohoff, R. M., Foster, G. R., & Stark, G. R. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2422 · Cited by 1,154 · see citing works

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

MEURS, E. F., Chong, K. L., GALABRU, J., Thomas, N. S. B., Kerr, I. M., Williams, B. R. G., & Hovanessian, A. G. (1990) · Cell · doi:10.1016/0092-8674(90)90374-n · Cited by 1,017 · see citing works

Interferon modulation of cellular microRNAs as an antiviral mechanism

Pedersen, I. M., Cheng, G., Wieland, S. F., Volinia, S., Croce, C. M., Chisari, F. V., & David, M. (2007) · Nature · doi:10.1038/nature06205 · Cited by 850 · see citing works

Impaired response to interferon-α/β and lethal viral disease in human STAT1 deficiency

Boisson‐Dupuis, S., Jouanguy, E., Al-Hajjar, S. H., Fieschi, C., Al-Mohsen, I. Z., Aljumaah, S., Yang, K., Chapgier, A. L. A., Eidenschenk, C., Eid, P., et al. (2003) · Nature Genetics · doi:10.1038/ng1097 · Cited by 814 · see citing works

Herpes Simplex Virus Encephalitis in Human UNC-93B Deficiency

Casrouge, A., Zhang, S.-Y., Eidenschenk, C., Jouanguy, E., Puel, A., Yang, K., Alcais, A., Picard, C., Mahfoufi, N., Nicolas, N., et al. (2006) · Science · doi:10.1126/science.1128346 · Cited by 749 · see citing works

Human Tyrosine Kinase 2 Deficiency Reveals Its Requisite Roles in Multiple Cytokine Signals Involved in Innate and Acquired Immunity

Minegishi, Y., Saitō, M., Morio, T., Watanabe, K., Agematsu, K., Tsuchiya, S., Takada, H., Hara, T., Kawamura, N., Ariga, T., et al. (2006) · Immunity · doi:10.1016/j.immuni.2006.09.009 · Cited by 701 · see citing works

Viral Encounters with 2′,5′-Oligoadenylate Synthetase and RNase L during the Interferon Antiviral Response

Silverman, R. H. (2007) · Journal of Virology · doi:10.1128/jvi.01471-07 · Cited by 677 · see citing works

Small self-RNA generated by RNase L amplifies antiviral innate immunity

Malathi, K., Dong, B., Gale, M., & Silverman, R. H. (2007) · Nature · doi:10.1038/nature06042 · Cited by 636 · see citing works

Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase.

Yang, Y. L., Reis, L. F. L., Pavlovic, J., Aguzzi, A., Schäfer, R., Kumar, A., Williams, B. R. G., Aguet, M., & Weissmann, C. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb00300.x · Cited by 632 · see citing works

Pillars Article: Virus Interference. I. The Interferon. Proc R Soc Lond B Biol Sci. 1957. 147: 258-267

Isaacs, A., & Lindenmann, J.-M. (2015) · The Journal of Immunology · doi:10.1093/jimmunol/195.5.1911 · Cited by 602 · see citing works

Lambda Interferon (IFN-λ), a Type III IFN, Is Induced by Viruses and IFNs and Displays Potent Antiviral Activity against Select Virus Infections In Vivo

Ank, N., West, H., Bartholdy, C., Eriksson, K., Thomsen, A. R., & Paludan, S. R. (2006) · Journal of Virology · doi:10.1128/jvi.80.9.4501-4509.2006 · Cited by 598 · see citing works

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

Kumar, A., Haque, J., Lacoste, J., Hiscott, J. B., & Williams, B. R. G. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.14.6288 · Cited by 568 · see citing works

Interferon action and apoptosis are defective in mice devoid of 2′,5′‐oligoadenylate‐dependent RNase L

Zhou, A., Paranjape, J., Brown, T. L., Nie, H., Naik, S., Dong, B., Chang, A., Trapp, B., Fairchild, R., Colmenares, C., et al. (1997) · The EMBO Journal · doi:10.1093/emboj/16.21.6355 · Cited by 559 · see citing works

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses

Lenschow, D. J., Lai, C. J., Frias‐Staheli, N., Giannakopoulos, N. V., Lutz, A., Wolff, T., Osiak, A., Levine, B., Schmidt, R. E., García‐Sastre, A., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607038104 · Cited by 557 · see citing works

Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)‐induced ubiquitin‐like ISG15 protein

Yuan, W., & Krug, R. M. (2001) · The EMBO Journal · doi:10.1093/emboj/20.3.362 · Cited by 532 · see citing works

UBP43 (USP18) Specifically Removes ISG15 from Conjugated Proteins

Malakhov, M. P., Malakhova, O. A., Kim, K. I., Ritchie, K. J., & Zhang, D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109078200 · Cited by 531 · see citing works

Essential Role for the dsRNA-Dependent Protein Kinase PKR in Innate Immunity to Viral Infection

Balachandran, S., Roberts, P. C., Brown, L. E., Truong, H., Pattnaik, A. K., Archer, D. R., & Barber, G. N. (2000) · Immunity · doi:10.1016/s1074-7613(00)00014-5 · Cited by 527 · see citing works

Germline mutations in the ribonuclease L gene in families showing linkage with HPC1

Carpten, J. D., Nupponen, N. N., Isaacs, S. D., Sood, R. B., Robbins, C. M., Xu, J., Faruque, M. U., Moses, T. Y., Ewing, C. M., Gillanders, E. M., et al. (2002) · Nature Genetics · doi:10.1038/ng823 · Cited by 525 · see citing works

Type I Interferon Production Enhances Susceptibility to Listeria monocytogenes Infection

O’Connell, R. M., Saha, S. K., Vaidya, S. A., Bruhn, K. W., Miranda, G. A., Zarnegar, B. J., Perry, A. K., Nguyen, B. D., Lane, T. F., Taniguchi, T., et al. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20040712 · Cited by 489 · see citing works

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways

Zhao, C., Denison, C., Huibregtse, J. M., Gygi, S. P., & Krug, R. M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504754102 · Cited by 471 · see citing works

PACT, a protein activator of the interferon‐induced protein kinase, PKR

Patel, R. C., & Sen, G. C. (1998) · The EMBO Journal · doi:10.1093/emboj/17.15.4379 · Cited by 457 · see citing works

Inhibition of cell-free protein synthesis by pppA2′ p5′ A2′ p5′ A: a novel oligonucleotide synthesized by interferon-treated L cell extracts

Clemens, M. J., & Williams, B. (1978) · Cell · doi:10.1016/0092-8674(78)90329-x · Cited by 440 · see citing works

Interferon-mediated protein kinase and low-molecular-weight inhibitor of protein synthesis

Roberts, W. K., Hovanessian, A. G., BROWN, R. E., Clemens, M. J., & Kerr, I. M. (1976) · Nature · doi:10.1038/264477a0 · Cited by 437 · see citing works

The interferon-inducible 15-kDa ubiquitin homolog conjugates to intracellular proteins.

Loeb, K. R., & Haas, A. L. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42585-9 · Cited by 436 · see citing works

Ovarian Tumor Domain-Containing Viral Proteases Evade Ubiquitin- and ISG15-Dependent Innate Immune Responses

Frias‐Staheli, N., Giannakopoulos, N. V., Kikkert, M., Taylor, S. L., Bridgen, A., Paragas, J., Richt, J. A., Rowland, R. R. R., Schmaljohn, C. S., Lenschow, D. J., et al. (2007) · Cell Host & Microbe · doi:10.1016/j.chom.2007.09.014 · Cited by 369 · see citing works

Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

Dey, M., Cao, C., Dar, A. C., Tamura, T., Ozato, K., Sicheri, F., & Dever, T. E. (2005) · Cell · doi:10.1016/j.cell.2005.06.041 · Cited by 366 · see citing works

Innate antiviral response targets HIV-1 release by the induction of ubiquitin-like protein ISG15

Okumura, A., Lu, G., Pitha, I., & Pitha, P. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510518103 · Cited by 363 · see citing works

Interferon Action: RNA Cleavage Pattern of a (2′-5′)Oligoadenylate—Dependent Endonuclease

Floyd-Smith, G., Slattery, E., & Lengyel, P. (1981) · Science · doi:10.1126/science.6165080 · Cited by 362 · see citing works

Influenza Virus NS1 Protein Counteracts PKR-Mediated Inhibition of Replication

Bergmann, M., Garcia-Sastre, A., Carnero, E., Pehamberger, H., Wolff, K., Palese, P., & Muster, T. (2000) · Journal of Virology · doi:10.1128/jvi.74.13.6203-6206.2000 · Cited by 362 · see citing works

The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4

Hsu, L.-C., Park, J. M., Zhang, K., Luo, J., Maeda, S., Kaufman, R. J., Eckmann, L., Guiney, D. G., & Karin, M. (2004) · Nature · doi:10.1038/nature02405 · Cited by 357 · see citing works

The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-α/β-induced ubiquitin-like protein

Zhao, C., Beaudenon, S. L., Kelley, M. L., Waddell, M. B., Yuan, W., Schulman, B. A., Huibregtse, J. M., & Krug, R. M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402528101 · Cited by 325 · see citing works

The Interferon-induced Double-Stranded RNA-Activated Protein Kinase Induces Apoptosis

Lee, S. B., & Estéban, M. (1994) · Virology · doi:10.1006/viro.1994.1151 · Cited by 324 · see citing works

Interferon action—sequence specificity of the ppp(A2′p)nA-dependent ribonuclease

Wreschner, D. H., McCauley, J. W., Skehel, J. J., & Kerr, I. M. (1981) · Nature · doi:10.1038/289414a0 · Cited by 321 · see citing works

Structure of the double‐stranded RNA‐binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA‐mediated activation

Nanduri, S., Carpick, B. W., Yang, Y., Williams, B. R. G., & Qin, J. (1998) · The EMBO Journal · doi:10.1093/emboj/17.18.5458 · Cited by 312 · see citing works

cDNA Structures and Regulation of Two Interferon-Induced Human Mx Proteins

Aebi, M., Fäh, J., Hurt, N., Samuel, C., Thomis, D. C., Bazzigher, L., Pavlovic, J., Haller, O., & Staeheli, P. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.11.5062 · Cited by 305 · see citing works

The Interferon-inducible Ubiquitin-protein Isopeptide Ligase (E3) EFP Also Functions as an ISG15 E3 Ligase

Zou, W., & Zhang, D. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m510787200 · Cited by 305 · see citing works

HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets

Wong, J. J.-Y., Pung, Y. F., Sze, N. S.-K., & Chin, K.-C. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600397103 · Cited by 295 · see citing works

Autophosphorylation in the Activation Loop Is Required for Full Kinase Activity In Vivo of Human and Yeast Eukaryotic Initiation Factor 2α Kinases PKR and GCN2

Romano, P. R., Garcia-Barrio, M. T., Zhang, X., Wang, Q., Taylor, D. R., Zhang, F., Herring, C., Mathews, M. B., Qin, J., & Hinnebusch, A. G. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.4.2282 · Cited by 272 · see citing works

Immunity by ubiquitylation: a reversible process of modification

Liu, Y.-C., Penninger, J., & Karin, M. (2005) · Nature reviews. Immunology · doi:10.1038/nri1731 · Cited by 271 · see citing works

Identification of Interferon-Stimulated Gene 15 as an Antiviral Molecule during Sindbis Virus Infection In Vivo

Lenschow, D. J., Giannakopoulos, N. V., Gunn, L. J., Johnston, C., O'Guin, A. K., Schmidt, R. E., Levine, B., & Virgin, H. W. (2005) · Journal of Virology · doi:10.1128/jvi.79.22.13974-13983.2005 · Cited by 268 · see citing works

Identification of the Zebrafish IFN Receptor: Implications for the Origin of the Vertebrate IFN System

Levraud, J., Boudinot, P., Colin, I., Benmansour, A., Peyriéras, N., Herbomel, P., & Lutfalla, G. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.7.4385 · Cited by 242 · see citing works

PKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in Neurons

Samuel, M. A., Whitby, K., Keller, B. C., Marri, A., Barchet, W., Williams, B. R. G., Silverman, R. H., Gale, M., & Diamond, M. (2006) · Journal of Virology · doi:10.1128/jvi.00489-06 · Cited by 241 · see citing works

Identification and Characterization of Interferon-Induced Proteins That Inhibit Alphavirus Replication

Zhang, Y., Burke, C. W., Ryman, K. D., & Klimstra, W. B. (2007) · Journal of Virology · doi:10.1128/jvi.01282-07 · Cited by 241 · see citing works

Proteomic identification of proteins conjugated to ISG15 in mouse and human cells

Giannakopoulos, N. V., Luo, J.-K., Papov, V. V., Zou, W., Lenschow, D. J., Jacobs, B., Borden, E. C., Li, J., Virgin, H. W., & Zhang, D. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.08.132 · Cited by 236 · see citing works

PKR Stimulates NF-κB Irrespective of Its Kinase Function by Interacting with the IκB Kinase Complex

Bonnet, M., Weil, R., Dam, E., Hovanessian, A. G., & MEURS, E. F. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.13.4532-4542.2000 · Cited by 234 · see citing works

The Human 2',5'-Oligoadenylate Synthetase Family: Interferon-Induced Proteins with Unique Enzymatic Properties

Rebouillat, D., & Hovanessian, A. G. (1999) · Journal of Interferon & Cytokine Research · doi:10.1089/107999099313992 · Cited by 232 · see citing works

Interferon-Inducible Ubiquitin E2, Ubc8, Is a Conjugating Enzyme for Protein ISGylation

Kim, K. I., Giannakopoulos, N. V., Virgin, H. W., & Zhang, D. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.21.9592-9600.2004 · Cited by 231 · see citing works

Characterization of Transgenic Mice with Targeted Disruption of the Catalytic Domain of the Double-stranded RNA-dependent Protein Kinase, PKR

Abraham, N. B., Stojdl, D. F., Duncan, P. I., Méthot, N., Ishii, T. M., Dubé, M., Vanderhyden, B. C., Atkins, H. L., Gray, D. A., McBurney, M. W., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.9.5953 · Cited by 231 · see citing works

Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene

Leib, D. A., Machalek, M. A., Williams, B. R. G., Silverman, R. H., & Virgin, H. W. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.100415697 · Cited by 230 · see citing works

In vitro and in vivo secretion of human ISG15, an IFN-induced immunomodulatory cytokine

D’Cunha, J., Ramanujam, S. K., Wagner, R. J., Witt, P. L., Knight, E., & Borden, E. C. (1996) · The Journal of Immunology · doi:10.4049/jimmunol.157.9.4100 · Cited by 223 · see citing works

5’-triphosphate-dependent activation of PKR by RNAs with short stem-loops

Nallagatla, S. R., Hwang, J., Toroney, R., Zheng, X., Cameron, C. E., & Bevilacqua, P. C. (2007) · Science · doi:10.1126/science.1147347 · Cited by 222 · see citing works

Inhibition of PKR by RNA and DNA viruses

Langland, J., Cameron, J. M., Heck, M. C., Jancovich, J. K., & Jacobs, B. L. (2006) · Virus Research · doi:10.1016/j.virusres.2005.10.014 · Cited by 222 · see citing works

IFN-inducible GTPases and immunity to intracellular pathogens

MacMicking, J. D. (2004) · Trends in Immunology · doi:10.1016/j.it.2004.08.010 · Cited by 221 · see citing works

Polymorphisms in interferon-induced genes and the outcome of hepatitis C virus infection: roles of MxA, OAS-1 and PKR

Knapp, S., Yee, L. J., Frodsham, A. J., Hennig, B. J., Hellier, S. C., Zhang, L., Wright, M., Chiaramonte, M., Graves, M. C., Thomas, H. C., et al. (2003) · Genes and Immunity · doi:10.1038/sj.gene.6363984 · Cited by 220 · see citing works

ISG15, an Interferon-Stimulated Ubiquitin-Like Protein, Is Not Essential for STAT1 Signaling and Responses against Vesicular Stomatitis and Lymphocytic Choriomeningitis Virus

Osiak, A., Utermöhlen, O., Niendorf, S., et al. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.15.6338-6345.2005 · Cited by 214 · see citing works

ISG15 Inhibits Nedd4 Ubiquitin E3 Activity and Enhances the Innate Antiviral Response*

Malakhova, O. A., & Zhang, D. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.c800030200 · Cited by 209 · see citing works

The human 2′-5′oligoadenylate synthetase family: Unique interferon-inducible enzymes catalyzing 2′-5′ instead of 3′-5′ phosphodiester bond formation

Hovanessian, A. G., & Justesen, J. (2007) · Biochimie · doi:10.1016/j.biochi.2007.02.003 · Cited by 202 · see citing works

Nature of inhibitor of cell-free protein synthesis formed in response to interferon and double-stranded RNA

Kerr, I. M., BROWN, R. E., & Hovanessian, A. G. (1977) · Nature · doi:10.1038/268540a0 · Cited by 197 · see citing works

The Murine Double-Stranded RNA-Dependent Protein Kinase PKR Is Required for Resistance to Vesicular Stomatitis Virus

Stojdl, D. F., Abraham, N. B., Knowles, S., Marius, R. M., Brasey, A., Lichty, B. D., Brown, E. G., Sonenberg, N., & Bell, J. C. (2000) · Journal of Virology · doi:10.1128/jvi.74.20.9580-9585.2000 · Cited by 196 · see citing works

Interferon-induced human MxA GTPase blocks nuclear import of Thogoto virus nucleocapsids

Kochs, G., & Haller, O. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.5.2082 · Cited by 195 · see citing works

Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene

Grimm, D. G., Staeheli, P., Hufbauer, M., Koerner, I., Martínez‐Sobrido, L., Solórzano, A., García‐Sastre, A., Haller, O., & Kochs, G. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701849104 · Cited by 192 · see citing works

Inhibition of Hepatitis B Virus Replication by the Interferon-Inducible MxA Protein

Gordien, E., Rosmorduc, O., Peltekian, C., Garreau, F., Bréchot, C., & Kremsdorf, D. (2001) · Journal of Virology · doi:10.1128/jvi.75.6.2684-2691.2001 · Cited by 190 · see citing works

A dynamically tuned double‐stranded RNA binding mechanism for the activation of antiviral kinase PKR

Nanduri, S., Rahman, F., Williams, B. R. G., & Qin, J. (2000) · The EMBO Journal · doi:10.1093/emboj/19.20.5567 · Cited by 188 · see citing works

Transgenic mice with intracellular immunity to influenza virus

Arnheiter, H., Skuntz, S., Noteborn, M. H. M., Chang, S., & Meier, E. (1990) · Cell · doi:10.1016/0092-8674(90)90239-b · Cited by 187 · see citing works

Crystal Structure of the 2′-Specific and Double-Stranded RNA-Activated Interferon-Induced Antiviral Protein 2′-5′-Oligoadenylate Synthetase

Hartmann, R., Justesen, J., Sarkar, S. N., Sen, G. C., & Yee, V. C. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00433-7 · Cited by 182 · see citing works

ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHPPreprint

Okumura, F., Zou, W., & Zhang, D. (2007) · Genes & Development · doi:10.1101/gad.1521607 · Cited by 182 · see citing works

Interferon, Mx, and viral countermeasures

Haller, O., Kochs, G., & Weber, F. (2007) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2007.06.001 · Cited by 179 · see citing works

Translation Inhibition in Apoptosis

Saelens, X., Kalai, M., & Vandenabeele, P. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103674200 · Cited by 177 · see citing works

Blockade of Interferon Induction and Action by the E3L Double-Stranded RNA Binding Proteins of Vaccinia Virus

Xiang, Y., CONDIT, R. C., Vijaysri, S., Jacobs, B. L., Williams, B. R. G., & Silverman, R. H. (2002) · Journal of Virology · doi:10.1128/jvi.76.10.5251-5259.2002 · Cited by 177 · see citing works

Nuclear MxA proteins form a complex with influenza virus NP and inhibit the transcription of the engineered influenza virus genome

Turan, K. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh192 · Cited by 173 · see citing works

Resistance of mice to mouse-adapted influenza A virus

Lindenmann, J. (1962) · Virology · doi:10.1016/0042-6822(62)90297-0 · Cited by 171 · see citing works

Molecular characterization of the interferon-induced 15-kDa protein. Molecular cloning and nucleotide and amino acid sequence.

Blomstrom, D. C., Fahey, D., Kutny, R. M., Korant, B. D., & Knight, E. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)84453-8 · Cited by 161 · see citing works

Selectivity in ISG15 and ubiquitin recognition by the SARS coronavirus papain-like protease

Lindner, H. A., Lytvyn, V., Qi, H., Lachance, P., Ziomek, E., & Menard, R. (2007) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2007.07.006 · Cited by 159 · see citing works

Genetically determined, interferon-dependent resistance to influenza virus in mice.

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Intrinsic molecular activities of the interferon-induced 2-5A-dependent RNase.

Dong, B., Xu, L., Zhou, A., Hassel, B. A., Lee, X., Torrence, P. F., & Silverman, R. H. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36767-4 · Cited by 157 · see citing works

Variation in Antiviral 2′,5′-Oligoadenylate Synthetase (2′5′AS) Enzyme Activity Is Controlled by a Single-Nucleotide Polymorphism at a Splice-Acceptor Site in the OAS1 Gene

Bonnevie‐Nielsen, V., Field, L. L., Lu, S., Zheng, D., Li, M., Martensen, P. M., Nielsen, T. B., Beck‐Nielsen, H., Lau, Y., & Pociot, F. (2005) · The American Journal of Human Genetics · doi:10.1086/429391 · Cited by 155 · see citing works

Host gene influences sensitivity to interferon action selectively for influenza virus

Haller, O., Arnheiter, H., Lindenmann, J.-M., et al. (1980) · Nature · doi:10.1038/283660a0 · Cited by 154 · see citing works

Conjugation of the 15-kDa Interferon-induced Ubiquitin Homolog Is Distinct from That of Ubiquitin

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Inhibition of L-Deleted Foot-and-Mouth Disease Virus Replication by Alpha/Beta Interferon Involves Double-Stranded RNA-Dependent Protein Kinase

Chinsangaram, J., Koster, M. J., & Grubman, M. J. (2001) · Journal of Virology · doi:10.1128/jvi.75.12.5498-5503.2001 · Cited by 145 · see citing works

PKR-Dependent and -Independent Mechanisms Are Involved in Translational Shutoff during Sindbis Virus Infection

Gorchakov, R. V., Frolova, E. I., Williams, B., et al. (2004) · Journal of Virology · doi:10.1128/jvi.78.16.8455-8467.2004 · Cited by 141 · see citing works

Human MxA Protein Inhibits the Replication of Crimean-Congo Hemorrhagic Fever Virus

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TRAF Family Proteins Link PKR with NF-κB Activation

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Interferon-Stimulated Gene 15 and the Protein ISGylation System

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