The DOI matches its Crossref record.
Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair
Open accessAbstract
Following publication, the authors identified an error in Figure S7.Specifically, during preparation of the accepted manuscript for publication, an incorrect version of the figure was included that contained two additional figure panels.This led to a mismatch in calling out the correct figure panels in the Results section, where the figures presented as S7H and S7I were referred to as S7F and S7G. Figure S7 has now been corrected online to remove the two additional panels.The authors apologize for this mistake and any confusion it may have caused.Additionally, the authors noted a couple of spelling mistakes.Firstly, the surname of one of the co-authors was unfortunately misspelled; as a result, ''Aime ´e Buglar-Lamb'' has been changed to ''Aime ´e Bugler-Lamb.''Secondly, affiliation 2 was changed to ''Faculty of Sciences'' instead of ''Faculty of Science.''Lastly, the work was funded by an FWO grant with reference number 3G000519 instead of 3G00519.These errors have also been corrected online, and the authors apologize for any inconvenience caused.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Efferocytosis of bone marrow-derived macrophages upregulates LAM-associated gene expression.
“Efferocytosis of bone marrow-derived macrophages (BMDM) was found to upregulate LAM-associated gene expression, and TREM2 overexpression in both LAM and LAM-like KCs was required for tissue repair, partly through enhanced efferocytic capacity in the CCl4 model.”
From Strategies to promote liver fibrosis amelioration with involvement of restorative macrophages (2026) · cites this paper as [11]
Similar LAM-like KCs were identified in human liver samples from patients with APAP overdose.
“Similar LAM-like KCs were identified in human liver samples from patients with APAP overdose.”
From Strategies to promote liver fibrosis amelioration with involvement of restorative macrophages (2026) · cites this paper as [11]
In APAP and CCl4 models, resident KCs persist but acquire a LAM-like phenotype.
“In these contexts, resident KCs persist but acquire a LAM-like phenotype.”
From Strategies to promote liver fibrosis amelioration with involvement of restorative macrophages (2026) · cites this paper as [11]
LAMs also emerge in APAP-induced acute injury and CCl4-induced fibrosis.
“De Ponti et al. (11) further showed that LAMs also emerge in other liver injury models, including acetaminophen (APAP)-induced acute injury and carbon tetrachloride (CCl4)-induced fibrosis.”
From Strategies to promote liver fibrosis amelioration with involvement of restorative macrophages (2026) · cites this paper as [11]
TREM2 overexpression in both LAM and LAM-like KCs is required for tissue repair, partly through enhanced efferocytic capacity in the CCl4 model.
“Efferocytosis of bone marrow-derived macrophages (BMDM) was found to upregulate LAM-associated gene expression, and TREM2 overexpression in both LAM and LAM-like KCs was required for tissue repair, partly through enhanced efferocytic capacity in the CCl4 model.”
From Strategies to promote liver fibrosis amelioration with involvement of restorative macrophages (2026) · cites this paper as [11]
Citations
Cites
Still being checked.
Cited by
Sorted by citations
Metabolic dysfunction and alcohol-associated liver disease (MetALD)
Gao, B., Arab, J. P., Liangpunsakul, S., Ding, W., Szabó, G., Mehal, W. Z., Wang, H., He, Y., Stärkel, P., Llorente, C., et al. (2025) · eGastroenterology · doi:10.1136/egastro-2025-100319 · Cited by 43
Myeloid cells in chronic liver inflammation
Patseas, D., El-Masry, A., Liu, Z., Ramachandran, P., & Triantafyllou, E. (2025) · Cellular and Molecular Immunology · doi:10.1038/s41423-025-01324-4 · Cited by 20
Self-citationYu, M., & Fu, J. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1749098 · Cited by 4
Batchuluun, B., Thoné, T., Djalalvandi, A., Fayyazi, R., Deo, P., Yabut, J. M., Maggiore, S., Vanneste, B., Gautam, J., Townsend, L. K., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116607 · Cited by 2
Self-citationStrategies to promote liver fibrosis amelioration with involvement of restorative macrophages
Aquino, J. B. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1792423 · Cited by 1
Kim, H., & Lachmann, N. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1767691 · Cited by 2
Shi, L., Zhou, H., & Zheng, R. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1793796 · Cited by 1
Mukherjee, S., Korbelius, M., Pirchheim, A., Schwarz, B., Diaz, M., Schooltink, L., Grabner, G. F., Vujić, N., & Kratky, D. (2026) · Molecular Metabolism · doi:10.1016/j.molmet.2026.102369
The Key Role of Complement Receptor CRIg in Kupffer Cell-Mediated Liver Disease Progression
Sun, X., & Liu, Y. (2026) · Viruses · doi:10.3390/v18040473
Peiseler, M. (2026) · Journal of Hepatology · doi:10.1016/j.jhep.2026.04.004
Macrophages in MASLD: from inflammatory and metabolic crosstalk to exercise intervention
Sun, Y. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1894884 · Cited by 1
Kotlyarov, S. N., Котлярова, А. А., Catanzaro, R., & Marotta, F. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27198614
Lv, Y., Shi, M., Zhao, Y., Yu, Y., Jia, W., & Hai, Z. (2026) · Clinical and Translational Medicine · doi:10.1002/ctm2.70863
Metadata
- Authors
- De Ponti, F. F., Bujko, A., Liu, Z., Collins, P. J., Schuermans, S., Maueröder, C., Amstelveen, S., Thoné, T., Martens, L., McKendrick, J. G., Louwe, P. A., Cruz, A. S., Saelens, W., Matchett, K. P., Waller, K. J., Zwicker, C., Bugler-Lamb, A., Vanneste, B., Parmentier, F., Abdul Latib, M. B., Remmerie, A., Kertesz, L., Kremer, A., Verbeke, J., Ipsen, D. H., Pfister, D. R., Liu, Z., Guilliams, M., Henderson, N. C., Ravichandran, K., Marques, P. E., & Scott, C. L.
- Corresponding author
- Scott, Charlotte L.
- ORCID
- Bujko, Anna
- Collins, Paul J.
- Schuermans, Sara
- Maueröder, Christian
- Amstelveen, Seraja
- Thoné, Tinne
- Martens, Liesbet
- McKendrick, John G.
- Louwe, Pieter A.
- Saelens, Wouter
- Matchett, Kylie P.
- Waller, Kathryn J.
- Bugler-Lamb, Aimée
- Vanneste, Bavo
- Remmerie, Anneleen
- Ipsen, David Højland
- Pfister, Dominik Reinhard
- Liu, Zhaoyuan
- Guilliams, Martin
- Henderson, Neil C.
- Ravichandran, Kodi
- Marques, Pedro E.
- Scott, Charlotte L.
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2025-07
- Volume
- 58
- Issue
- 7
- Pages
- 1867-1868
- ISSN
- 1074-7613 (ISSN-L)
- OpenAlex
- W4411095901
- Cited by
- 13
- References
- 0
- Citations by year
- 2026: 10 · 2025: 3
- FWCI
- 7.31
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Immunity (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- Fonds Wetenschappelijk Onderzoek (3G000519)
- Topics
- Health Sciences › Medicine › Hepatology › Liver physiology and pathology
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Health Sciences › Medicine › Surgery › Wound Healing and Treatments
- Keywords
- hepatic macrophages, tissue repair, liver regeneration, ontogeny, spatial constraints, Kupffer cells, liver fibrosis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
