Scott, Charlotte L.

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

Bain, C. C., Bravo-Blas, A., Scott, C. L., Gomez Perdiguero, E., Geissmann, F., Henri, S., Malissen, B., Osborne, L. C., Artis, D., & Mowat, A. M. (2014) · Nature Immunology

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 1,178

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

Van Hove, H., Martens, L., Scheyltjens, I., De Vlaminck, K., Pombo Antunes, A. R., De Prijck, S., Vandamme, N., De Schepper, S., Van Isterdael, G., Scott, C. L., et al. (2019) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 1,074

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

Guilliams, M., Bonnardel, J., Haest, B., Vanderborght, B., Wagner, C., Remmerie, A., Bujko, A., Martens, L., Thoné, T., Browaeys, R., et al. (2022) · Cell

Single-cell and spatial transcriptomicsLiver physiology and pathology

Cited by 985

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

Scott, C. L., Zheng, F., De Baetselier, P., Martens, L., Saeys, Y., De Prijck, S., Lippens, S., Abels, C., Schoonooghe, S., Raes, G., et al. (2016) · Nature Communications

Liver physiology and pathologyImmune cells in cancer

Cited by 860

Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

Bonnardel, J., T’Jonck, W., Gaublomme, D., Browaeys, R., Scott, C. L., Martens, L., Vanneste, B., De Prijck, S., Nedospasov, S. A., Kremer, A., et al. (2019) · Immunity

Liver physiology and pathologyImmune cells in cancer

Cited by 631

Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver

Remmerie, A., Martens, L., Thoné, T., Castoldi, A., Seurinck, R., Pavie, B., Roels, J., Vanneste, B., De Prijck, S., Vanhockerhout, M., et al. (2020) · Immunity

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 592

Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities

Bain, C. C., Hawley, C. A., Garner, H., Scott, C. L., Schridde, A., Steers, N. J., Mack, M., Joshi, A., Guilliams, M., Mowat, A. M. I., et al. (2016) · Nature Communications

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 527

Does niche competition determine the origin of tissue-resident macrophages?

Guilliams, M., & Scott, C. L. (2017) · Nature Reviews Immunology

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 409

Liver macrophages in health and disease

Guilliams, M., & Scott, C. L. (2022) · Immunity

Liver physiology and pathologyImmune cells in cancer

Cited by 395

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

Voet, S., Mc Guire, C., Hagemeyer, N., Martens, A., Schroeder, A., Wieghofer, P., Daems, C., Staszewski, O., Vande Walle, L., Jordao, M. J. C., et al. (2018) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

Cited by 227

Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair

De Ponti, F. F., Bujko, A., Liu, Z., Collins, P. J., Schuermans, S., Maueroder, C., Amstelveen, S., Thoné, T., Martens, L., McKendrick, J. G., et al. (2025) · Immunity

Liver physiology and pathologyImmune cells in cancer

Cited by 94

Osteopontin characterizes bile duct–associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis

De Muynck, K., Heyerick, L., De Ponti, F. F., Vanderborght, B., Meese, T., Van Campenhout, S., Baudonck, L., Gijbels, E., Rodrigues, P. M., Banales, J. M., et al. (2024) · Hepatology

Liver Diseases and ImmunityLiver physiology and pathology

Cited by 64

Hepatic Macrophage Responses in Inflammation, a Function of Plasticity, Heterogeneity or Both?

Zwicker, C., Bujko, A., & Scott, C. L. (2021) · Frontiers in Immunology

Immune cells in cancerLiver physiology and pathology

Cited by 41

Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair

De Ponti, F. F., Bujko, A., Liu, Z., Collins, P. J., Schuermans, S., Maueröder, C., Amstelveen, S., Thoné, T., Martens, L., McKendrick, J. G., et al. (2025) · Immunity

Liver physiology and pathologyImmune cells in cancer

Cited by 13

Targeting macrophages in liver fibrosis

González del Barrio, L., Ipsen, D. H., Pfister, D. R., Hancz, D., & Scott, C. L. (2026) · Frontiers in Immunology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 3