Ravichandran, Kodi S.

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

Elliott, M. R., Chekeni, F. B., Trampont, P. C., Lazarowski, E. R., Kadl, A., Walk, S. F., Park, D., Woodson, R. I., Ostankovich, M., Sharma, P., et al. (2009) · Nature

Phagocytosis and Immune RegulationAdenosine and Purinergic Signaling

Cited by 1,654

Apoptotic cell clearance: basic biology and therapeutic potential

Poon, I. K. H., Lucas, C. D., Rossi, A. G., & Ravichandran, K. S. (2014) · Nature Reviews Immunology

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 1,223

Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

Chekeni, F. B., Elliott, M. R., Sandilos, J. K., Walk, S. F., Kinchen, J. M., Lazarowski, E. R., Armstrong, A. J., Penuela, S., Laird, D. W., Salvesen, G. S., et al. (2010) · Nature

Adenosine and Purinergic SignalingCell death mechanisms and regulation

Cited by 1,120

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

Galluzzi, L., Bravo-San Pedro, J. M., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Alnemri, E. S., Altucci, L., Andrews, D., Annicchiarico-Petruzzelli, M., et al. (2015) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 1,002

Phagocytosis of apoptotic cells in homeostasis

Arandjelovic, S., & Ravichandran, K. S. (2015) · Nature Immunology

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 959

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

Kadl, A., Meher, A. K., Sharma, P. R., Lee, M. Y., Doran, A. C., Johnstone, S. R., Elliott, M. R., Gruber, F., Han, J., Chen, W., et al. (2010) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 573

Beginnings of a Good Apoptotic Meal: The Find-Me and Eat-Me Signaling Pathways

Ravichandran, K. S. (2011) · Immunity

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 559

Phagosome maturation: going through the acid test

Kinchen, J. M., & Ravichandran, K. S. (2008) · Nature Reviews Molecular Cell Biology

Phagocytosis and Immune RegulationCellular transport and secretion

Cited by 555

Clearing the Dead: Apoptotic Cell Sensing, Recognition, Engulfment, and Digestion

Hochreiter-Hufford, A., & Ravichandran, K. S. (2013) · Cold Spring Harbor Perspectives in Biology

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 503

Drugging the efferocytosis process: concepts and opportunities

Mehrotra, P., & Ravichandran, K. S. (2022) · Nature Reviews Drug Discovery

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 459

Living on the Edge: Efferocytosis at the Interface of Homeostasis and Pathology

Morioka, S., Maueröder, C., & Ravichandran, K. S. (2019) · Immunity

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 391

A pathway for phagosome maturation during engulfment of apoptotic cells

Kinchen, J. M., Doukoumetzidis, K., Almendinger, J., Stergiou, L., Tosello-Trampont, A., Sifri, C. D., Hengartner, M. O., & Ravichandran, K. S. (2008) · Nature Cell Biology

Cellular transport and secretionPhagocytosis and Immune Regulation

Cited by 284

Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane

Kenwood, B. M., Weaver, J. L., Bajwa, A., Poon, I. K., Byrne, F. L., Murrow, B. A., Calderone, J. A., Huang, L., Divakaruni, A. S., Tomsig, J. L., et al. (2014) · Molecular Metabolism

Mitochondrial Function and PathologyATP Synthase and ATPases Research

Cited by 243

Dock180 and ELMO1 Proteins Cooperate to Promote Evolutionarily Conserved Rac-dependent Cell Migration

Grimsley, C. M., Kinchen, J. M., Tosello-Trampont, A.-C., Brugnera, E., Haney, L. B., Lu, M., Chen, Q., Klingele, D., Hengartner, M. O., & Ravichandran, K. S. (2004) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 224

Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1

Fond, A. M., Lee, C. S., Schulman, I. G., Kiss, R. S., & Ravichandran, K. S. (2015) · Journal of Clinical Investigation

Cholesterol and Lipid MetabolismPhagocytosis and Immune Regulation

Cited by 114

A Steric-Inhibition Model for Regulation of Nucleotide Exchange via the Dock180 Family of GEFs

Lu, M., Kinchen, J. M., Rossman, K. L., Grimsley, C., Hall, M., Sondek, J., Hengartner, M. O., Yajnik, V., & Ravichandran, K. S. (2005) · Current Biology

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 102

Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair

De Ponti, F. F., Bujko, A., Liu, Z., Collins, P. J., Schuermans, S., Maueroder, C., Amstelveen, S., Thoné, T., Martens, L., McKendrick, J. G., et al. (2025) · Immunity

Liver physiology and pathologyImmune cells in cancer

Cited by 94

An essential role for calcium flux in phagocytes for apoptotic cell engulfment and the anti-inflammatory response

Gronski, M. A., Kinchen, J. M., Juncadella, I. J., Franc, N. C., & Ravichandran, K. S. (2009) · Cell Death & Differentiation

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 92

Context-dependent compensation among phosphatidylserine-recognition receptors

Penberthy, K. K., Rival, C., Shankman, L. S., Raymond, M. H., Zhang, J., Perry, J. S. A., Lee, C. S., Han, C. Z., Onengut-Gumuscu, S., Palczewski, K., et al. (2017) · Scientific Reports

Phagocytosis and Immune RegulationAutophagy in Disease and Therapy

Cited by 30

A Key Role for the Phosphorylation of Ser440 by the Cyclic AMP-dependent Protein Kinase in Regulating the Activity of the Src Homology 2 Domain-containing Inositol 5′-Phosphatase (SHIP1)

Zhang, J., Ravichandran, K. S., & Garrison, J. C. (2010) · Journal of Biological Chemistry

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 25

Regulation of the Src Homology 2 Domain-containing Inositol 5′-Phosphatase (SHIP1) by the Cyclic AMP-dependent Protein Kinase

Zhang, J., Walk, S. F., Ravichandran, K. S., & Garrison, J. C. (2009) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 18

Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair

De Ponti, F. F., Bujko, A., Liu, Z., Collins, P. J., Schuermans, S., Maueröder, C., Amstelveen, S., Thoné, T., Martens, L., McKendrick, J. G., et al. (2025) · Immunity

Liver physiology and pathologyImmune cells in cancer

Cited by 13

Cooperation between Noncanonical Ras Network Mutations

Stites, E. C., Trampont, P. C., Haney, L. B., Walk, S. F., & Ravichandran, K. S. (2015) · Cell Reports

Protein Kinase Regulation and GTPase SignalingCancer Genomics and Diagnostics

Cited by 6