The immunomodulatory properties of mesenchymal stem cells and their use for immunotherapy

Multilineage potential of adult human mesenchymal stem cells

Pittenger, M. F., Mackay, A. M., Beck, S. C., Jaiswal, R. K., Douglas, R., Mosca, J. D., Moorman, M. A., Simonetti, D. W., Craig, S., & Marshak, D. R. (1999) · Science · doi:10.1126/science.284.5411.143 · Cited by 21,052 · see citing works

Human Adipose Tissue Is a Source of Multipotent Stem Cells

Zuk, P. A., Zhu, M., Ashjian, P. H., Ugarte, D. A. D., Huang, J. I., Mizuno, H., Alfonso, Z. C., Fraser, J. K., Benhaim, P., & Hedrick, M. H. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-02-0105 · Cited by 6,669 · see citing works

Human mesenchymal stem cells modulate allogeneic immune cell responses

Aggarwal, S., & Pittenger, M. F. (2005) · Blood · doi:10.1182/blood-2004-04-1559 · Cited by 4,511 · see citing works

Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli

Di Nicola, M., Carlo-Stella, C., Magni, M., Milanesi, M., Longoni, P. D., Matteucci, P., Grisanti, S., & Gianni, A. M. (2002) · Blood · doi:10.1182/blood.v99.10.3838 · Cited by 3,226 · see citing works

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

Blanc, K. L., Frassoni, F., Ball, L. M., Locatelli, F., Roelofs, H., Lewis, I., Lanino, E., Sundberg, B., Bernardo, M. E., Remberger, M., et al. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60690-x · Cited by 2,692 · see citing works

Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo

Bartholomew, A. M., Sturgeon, C., Siatskas, M., Ferrer, K., McIntosh, K. R., Patil, S., Hardy, W., Devine, S. M., Ucker, D. S., Deans, R., et al. (2002) · Experimental Hematology · doi:10.1016/s0301-472x(01)00769-x · Cited by 2,296 · see citing works

Concise Review: Mesenchymal Stem/Multipotent Stromal Cells: The State of Transdifferentiation and Modes of Tissue Repair—Current Views

Phinney, D. G., & Prockop, D. J. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0637 · Cited by 1,910 · see citing works

Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase–mediated tryptophan degradation

Meisel, R., Zibert, A., Laryea, M. D., Göbel, U., Däubener, W., & Dilloo, D. (2004) · Blood · doi:10.1182/blood-2003-11-3909 · Cited by 1,638 · see citing works

HLA expression and immunologic propertiesof differentiated and undifferentiated mesenchymal stem cells

Blanc, K. L., Tammik, C., Rosendahl, K., Zetterberg, E., & Ringdén, O. T. H. (2003) · Experimental Hematology · doi:10.1016/s0301-472x(03)00110-3 · Cited by 1,624 · see citing works

Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide

Krampera, M., Glennie, S. J., Dyson, J., Scott, D. M., Laylor, R. M., Simpson, E., & Dazzi, F. (2003) · Blood · doi:10.1182/blood-2002-07-2104 · Cited by 1,597 · see citing works

Isolation of multipotent adult stem cells from the dermis of mammalian skin

Toma, J. G., Akhavan, M., Fernandes, K. J. L., Barnabé‐Heider, F., Sadikot, A. F., Kaplan, D. R., & Miller, F. D. (2001) · Nature Cell Biology · doi:10.1038/ncb0901-778 · Cited by 1,593 · see citing works

Role for Interferon-γ in the Immunomodulatory Activity of Human Bone Marrow Mesenchymal Stem Cells

Krampera, M., Cosmi, L., Angeli, R., Pasini, A., Liotta, F., Andreini, A., Santarlasci, V., Mazzinghi, B., Pizzolo, G., Vinante, F., et al. (2005) · Stem Cells · doi:10.1634/stemcells.2005-0008 · Cited by 1,311 · see citing works

Immunomodulatory effect of human adipose tissue‐derived adult stem cells: comparison with bone marrow mesenchymal stem cells

Puissant‐Lubrano, B., Barreau, C., Bourin, P., Clavel, C., Corre, J., Bousquet, C., Taureau, C., Cousin, B., Abbal, M., Laharrague, P. F., et al. (2005) · British Journal of Haematology · doi:10.1111/j.1365-2141.2005.05409.x · Cited by 957 · see citing works

Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells

Sato, K., Ozaki, K., Oh, I., Meguro, A., Hatanaka, K., Nagai, T., Muroi, K., & Ozawa, K. (2006) · Blood · doi:10.1182/blood-2006-02-002246 · Cited by 952 · see citing works

A Phase I Clinical Trial of the Treatment of Crohn's Fistula by Adipose Mesenchymal Stem Cell Transplantation

García‐Olmo, D., García‐Arranz, M., Herreros, D., Pascual, I., Peiró, C., & Rodríguez‐Montes, J. A. (2005) · Diseases of the Colon & Rectum · doi:10.1007/s10350-005-0052-6 · Cited by 799 · see citing works

Mesenchymal Stem Cells Inhibit Generation and Function of Both CD34+-Derived and Monocyte-Derived Dendritic Cells

Nauta, A. J., Kruisselbrink, A. B., Lurvink, E. G. A., Willemze, R., & Fibbe, W. E. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.4.2080 · Cited by 741 · see citing works

Adipose Tissue‐Derived Mesenchymal Stem Cells Have In Vivo Immunosuppressive Properties Applicable for the Control of the Graft‐Versus‐Host Disease

Yañez, R., Lamana, M. L., Garcı́a-Castro, J., Colmenero, I., Ramírez, M. R., & Bueren, J. A. (2006) · Stem Cells · doi:10.1634/stemcells.2006-0228 · Cited by 719 · see citing works

Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting

Nauta, A. J., Westerhuis, G., Kruisselbrink, A. B., Lurvink, E. G. A., Willemze, R., & Fibbe, W. E. (2006) · Blood · doi:10.1182/blood-2005-11-011650 · Cited by 694 · see citing works

Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis

González‐Rey, E., Anderson, P. O., González, M. A., Rico, L., Büscher, D., & Delgado, M. (2009) · Gut · doi:10.1136/gut.2008.168534 · Cited by 677 · see citing works

Species Variation in the Mechanisms of Mesenchymal Stem Cell-Mediated Immunosuppression

Ren, G., Su, J., Zhang, L., Zhao, X., Ling, W., L'huillie, A., Zhang, J., Lu, Y., Roberts, A. I., Ji, W., et al. (2009) · Stem Cells · doi:10.1002/stem.118 · Cited by 597 · see citing works

IFN‐γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

Polchert, D., Sobinsky, J., Douglas, G., Kidd, M. E., Moadsiri, A., Reina, E., Genrich, K., Mehrotra, S., Setty, S., Smith, B., et al. (2008) · European Journal of Immunology · doi:10.1002/eji.200738129 · Cited by 580 · see citing works

Prostaglandin E2–EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion

Yao, C., Sakata, D., Esaki, Y., Li, Y., Matsuoka, T., Kuroiwa, K., Sugimoto, Y., & Narumiya, S. (2009) · Nature Medicine · doi:10.1038/nm.1968 · Cited by 566 · see citing works

Pretransplant Infusion of Mesenchymal Stem Cells Prolongs the Survival of a Semiallogeneic Heart Transplant through the Generation of Regulatory T Cells

Casiraghi, F., Azzollini, N., Cassis, P., Imberti, B., Morigi, M., Cugini, D., Cavinato, R. A., Todeschini, M., Solini, S., Sonzogni, A., et al. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.6.3933 · Cited by 423 · see citing works

IFN-γ and TNF-α differentially regulate immunomodulation by murine mesenchymal stem cells

English, K., Barry, F., Field-Corbett, C., & Mahon, B. P. (2007) · Immunology Letters · doi:10.1016/j.imlet.2007.04.001 · Cited by 417 · see citing works

Bone Marrow Mesenchymal Stem Cells Suppress Lymphocyte Proliferation In Vitro but Fail to Prevent Graft-versus-Host Disease in Mice

Sudres, M., Norol, F., Trenado, A., Grégoire, S., Charlotte, F., Levacher, B., Lataillade, J., Bourin, P., Holy, X., Vernant, J., et al. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.12.7761 · Cited by 412 · see citing works

Mesenchymal Stem Cells Protect Breast Cancer Cells through Regulatory T Cells: Role of Mesenchymal Stem Cell-Derived TGF-β

Patel, S. A., Meyer, J. R., Greco, S. J., Corcoran, K. E., Bryan, M., & Rameshwar, P. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903143 · Cited by 364 · see citing works

Immunosuppressive Effects of Mesenchymal Stem Cells: Involvement of HLA-G

Nasef, A., Mathieu, N., Chapel, A., Frick, J., François, S., Mazurier, C., Boutarfa, A., Bouchet, S., Gorin, N.-C., Thierry, D., et al. (2007) · Transplantation · doi:10.1097/01.tp.0000267918.07906.08 · Cited by 350 · see citing works

Tumor Cell Invasion Inhibited by TIMP-2

Albini, A., Melchiori, A., Santi, L., Liotta, L. A., Brown, P. D. N., & Stetler‐Stevenson, W. G. (1991) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/83.11.775 · Cited by 321 · see citing works

Infusion of Mesenchymal Stem Cells and Rapamycin Synergize to Attenuate Alloimmune Responses and Promote Cardiac Allograft Tolerance

Ge, W., Jiang, J., Baroja, M. L., Arp, J., Zassoko, R., Liu, W., Bartholomew, A. M., García, B., & Wang, H. (2009) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2009.02721.x · Cited by 271 · see citing works

Human Mesenchymal Stem Cells Promote Survival of T Cells in a Quiescent State

Benvenuto, F., Ferrari, S., Gerdoni, E., Gualandi, F., Frassoni, F., Pistoia, V., Mancardi, G., & Uccelli, A. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0068 · Cited by 258 · see citing works

Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate

Popp, F., Eggenhofer, E., Renner, P., Slowik, P., Lang, S. A., Kaspar, H., Geissler, E. K., Piso, P., Schlitt, H. J., & Dahlke, M. H. (2008) · Transplant Immunology · doi:10.1016/j.trim.2008.08.004 · Cited by 196 · see citing works

Human Heart, Spleen, and Perirenal Fat-Derived Mesenchymal Stem Cells Have Immunomodulatory Capacities

Hoogduijn, M. J., Crop, M. J., Peeters, A. M. A., van Osch, G. J. V. M., Balk, A. H. M. M., IJzermans, J. N. M., Weimar, W., & Baan, C. C. (2007) · Stem Cells and Development · doi:10.1089/scd.2006.0110 · Cited by 189 · see citing works

Human mesenchymal stem cells inhibit antibody production induced in vitro by allostimulation

Comoli, P., Ginevri, F., Maccario, R., Avanzini, M. A., Marconi, M., Groff, A., Cometa, A. M., Cioni, M., Porretti, L., Barberi, W., et al. (2007) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfm740 · Cited by 148 · see citing works

Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen-presenting cell properties

François, M., Romieu, R., Stock-Martineau, S., Boivin, M., Bramson, J. L., & Galipeau, J. (2009) · Blood · doi:10.1182/blood-2009-02-207795 · Cited by 146 · see citing works

Lipidomic analysis of twenty‐seven prostanoids and isoprostanes by liquid chromatography/electrospray tandem mass spectrometry

Masoodi, M., & Nicolaou, A. (2006) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.2697 · Cited by 143 · see citing works

Bone Marrow-Derived Mesenchymal Stem Cells Ameliorate Autoimmune Enteropathy Independently of Regulatory T Cells

Parekkadan, B., Tilles, A. W., & Yarmush, M. L. (2008) · Stem Cells · doi:10.1634/stemcells.2007-0790 · Cited by 139 · see citing works

MHC expression kinetics and immunogenicity of mesenchymal stromal cells after short-term IFN-γ challenge

Chan, W. K., Lau, A. S. Y., Li, J., Law, H., Lau, Y., & Chan, G. (2008) · Experimental Hematology · doi:10.1016/j.exphem.2008.06.008 · Cited by 137 · see citing works

Mesenchymal Stem Cells Require a Sufficient, Ongoing Immune Response to Exert Their Immunosuppressive Function

Renner, P., Eggenhofer, E., Rosenauer, A., Popp, F., Steinmann, J., Slowik, P., Geissler, E. K., Piso, P., Schlitt, H. J., & Dahlke, M. H. (2009) · Transplantation Proceedings · doi:10.1016/j.transproceed.2009.06.119 · Cited by 127 · see citing works

Human Adipose Tissue-Derived Mesenchymal Stem Cells Induce Explosive T-Cell Proliferation

Crop, M. J., Baan, C. C., Korevaar, S. S., IJzermans, J. N. M., Weimar, W., & Hoogduijn, M. J. (2010) · Stem Cells and Development · doi:10.1089/scd.2009.0368 · Cited by 104 · see citing works

Susceptibility of Human Mesenchymal Stem Cells to Tacrolimus, Mycophenolic Acid, and Rapamycin

Hoogduijn, M. J., Crop, M. J., Korevaar, S. S., Peeters, A. M. A., Eijken, M., Maat, L. P. W. M., Balk, A. H. M. M., Weimar, W., & Baan, C. C. (2008) · Transplantation · doi:10.1097/tp.0b013e31818aa536 · Cited by 102 · see citing works

Use of donor bone marrow mesenchymal stem cells for treatment of skin allograft rejection in a preclinical rat model

Sbano, P., Cuccia, A., Mazzanti, B., Urbani, S., Giusti, B., Lapini, I., Rossi, L., Abbate, R., Marseglia, G., Nannetti, G., et al. (2008) · Archives of Dermatological Research · doi:10.1007/s00403-007-0827-9 · Cited by 99 · see citing works

Human Mesenchymal Stem Cells and Immunosuppressive Drug Interactions in Allogeneic Responses: An In Vitro Study Using Human Cells

Buron, F., Perrin, H., Malcus, C., Héquet, O., Thaunat, O., Sarda-Kolopp, M.-N., Touraine‐Moulin, F., & Morélon, E. (2009) · Transplantation Proceedings · doi:10.1016/j.transproceed.2009.08.030 · Cited by 85 · see citing works

Toward MSC in Solid Organ Transplantation: 2008 Position Paper of the MISOT Study Group

Dahlke, M. H., Hoogduijn, M. J., Eggenhofer, E., Popp, F., Renner, P., Slowik, P., Rosenauer, A., Piso, P., Geissler, E. K., Lange, C., et al. (2009) · Transplantation · doi:10.1097/tp.0b013e3181b4425a · Cited by 71 · see citing works

Mesenchymal stem cells as immunomodulators after liver transplantation

Popp, F., Renner, P., Eggenhofer, E., Slowik, P., Geissler, E. K., Piso, P., Schlitt, H. J., & Dahlke, M. H. (2009) · Liver Transplantation · doi:10.1002/lt.21862 · Cited by 61 · see citing works

Cell contact interaction between adipose‐derived stromal cells and allo‐activated T lymphocytes

Quaedackers, M. E., Baan, C. C., Weimar, W., & Hoogduijn, M. J. (2009) · European Journal of Immunology · doi:10.1002/eji.200939584 · Cited by 60 · see citing works

In vitro activated human T lymphocytes very efficiently attach to allogenic multipotent mesenchymal stromal cells and transmigrate under them

Suvà, D., Passweg, J. R., Arnaudeau, S., Hoffmeyer, P. J., & Kindler, V. (2007) · Journal of Cellular Physiology · doi:10.1002/jcp.21244 · Cited by 52 · see citing works

Overview of stem cell therapy for Crohn's disease

Dryden, G. W. (2009) · Expert Opinion on Biological Therapy · doi:10.1517/14712590902956615 · Cited by 45 · see citing works

Donor-Derived Mesenchymal Stem Cells Remain Present and Functional in the Transplanted Human Heart

Hoogduijn, M. J., Crop, M. J., Peeters, A., Korevaar, S. S., Eijken, M., Drabbels, J. J. M., Roelen, D. L., Maat, A. P. W. M., Balk, A. H. M. M., Weimar, W., et al. (2008) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2008.02450.x · Cited by 41 · see citing works

Biomaterial based modulation of macrophage polarization: a review and suggested design principles

Sridharan, R., Cameron, A. R., Kelly, D. J., Kearney, C. J., & O’Brien, F. J. (2015) · Materials Today · doi:10.1016/j.mattod.2015.01.019 · Cited by 826 · see citing works

Mesenchymal stromal cells derived from various tissues: Biological, clinical and cryopreservation aspects

Marquez-Curtis, L. A., Janowska-Wieczorek, A., McGann, L. E., & Elliott, J. A. W. (2015) · Cryobiology · doi:10.1016/j.cryobiol.2015.07.003 · Cited by 346 · see citing works

Cell Adhesion and Long-Term Survival of Transplanted Mesenchymal Stem Cells: A Prerequisite for Cell Therapy

Lee, S., Choi, E., Cha, M., & Hwang, K. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2015/632902 · Cited by 269 · see citing works

Adipose‐Derived Mesenchymal Stem Cells Exert Antiinflammatory Effects on Chondrocytes and Synoviocytes From Osteoarthritis Patients Through Prostaglandin E2

Manferdini, C., Maumus, M., Gabusi, E., Piacentini, A., Filardo, G., Peyrafitte, J.-A., Jørgensen, C., Bourin, P., Fleury‐Cappellesso, S., Facchini, A., et al. (2013) · Arthritis & Rheumatism · doi:10.1002/art.37908 · Cited by 250 · see citing works

Reprogramming Adult Schwann Cells to Stem Cell-like Cells by Leprosy Bacilli Promotes Dissemination of Infection

Masaki, T., Qu, J., Cholewa-Waclaw, J., Burr, K., Raaum, R. L., & Rambukkana, A. (2013) · Cell · doi:10.1016/j.cell.2012.12.014 · Cited by 237 · see citing works

Perivascular Human Endometrial Mesenchymal Stem Cells Express Pathways Relevant to Self-Renewal, Lineage Specification, and Functional Phenotype1

Spitzer, T., Rojas, A. M., Zelenko, Z., Aghajanova, L., Erikson, D. W., Barragan, F., Meyer, M., Tamaresis, J. S., Hamilton, A. E., Irwin, J. C., et al. (2011) · Biology of Reproduction · doi:10.1095/biolreprod.111.095885 · Cited by 213 · see citing works

Human Adipose Tissue-Derived Mesenchymal Stem Cells Abrogate Plasmablast Formation and Induce Regulatory B Cells Independently of T Helper Cells

Franquesa, M., Mensah, F. K., Huizinga, R., Strini, T., Boon, L., Lombardo, E., DelaRosa, O., Laman, J. D., Grinyo, J. M., Weimar, W., et al. (2014) · Stem Cells · doi:10.1002/stem.1881 · Cited by 213 · see citing works

mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation

Levy, O., Zhao, W., Mortensen, L. J., LeBlanc, S., Tsang, K., Fu, M., Phillips, J. A., Sagar, V., Anandakumaran, P. N., Ngai, J., et al. (2013) · Blood · doi:10.1182/blood-2013-04-495119 · Cited by 212 · see citing works

An early‐senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a pro‐inflammatory program

Gnani, D., Crippa, S., della Volpe, L., Rossella, V., Conti, A., Lettera, E., Rivis, S., Ometti, M., Fraschini, G., Bernardo, M. E., et al. (2019) · Aging Cell · doi:10.1111/acel.12933 · Cited by 188 · see citing works

Mesenchymal stem cell-educated macrophages

Eggenhofer, E., & Hoogduijn, M. J. (2012) · Transplantation Research · doi:10.1186/2047-1440-1-12 · Cited by 169 · see citing works

Mesenchymal Stem Cells in the Treatment of Traumatic Brain Injury

Hasan, A., Deeb, G., Rahal, R., Atwi, K. M., Mondello, S., Marei, H. E. S., Gali, A., & Sleiman, E. (2017) · Frontiers in Neurology · doi:10.3389/fneur.2017.00028 · Cited by 141 · see citing works

Wharton’s Jelly Mesenchymal Stem Cells as Candidates for Beta Cells Regeneration: Extending the Differentiative and Immunomodulatory Benefits of Adult Mesenchymal Stem Cells for the Treatment of Type 1 Diabetes

Anzalone, R., Iacono, M. L., Loria, T., di Stefano, A., Giannuzzi, P., Farina, F., & Larocca, G. (2011) · Stem Cell Reviews and Reports · doi:10.1007/s12015-010-9196-4 · Cited by 146 · see citing works

New Strategies for Overcoming Limitations of Mesenchymal Stem Cell-Based Immune Modulation

Kim, N., & Cho, S. (2015) · International Journal of Stem Cells · doi:10.15283/ijsc.2015.8.1.54 · Cited by 132 · see citing works

Double-edged-sword effect of IL-1β on the osteogenesis of periodontal ligament stem cells via crosstalk between the NF-κB, MAPK and BMP/Smad signaling pathways

Mao, C.-Y., Wang, Y.-G., Zhang, X., Zheng, X.-Y., Tang, T.-T., & Lu, E. Y. (2016) · Cell Death and Disease · doi:10.1038/cddis.2016.204 · Cited by 132 · see citing works

Antioxidant and anti-inflammatory effects of intravenously injected adipose derived mesenchymal stem cells in dogs with acute spinal cord injury

Kim, Y., Jo, S.-H., Kim, W. H., & Kweon, O. (2015) · Stem Cell Research & Therapy · doi:10.1186/s13287-015-0236-5 · Cited by 125 · see citing works

Implications of mesenchymal stem cells in regenerative medicine

Kariminekoo, S., Movassaghpour, A. A., Rahimzadeh, A., Talebi, M., Shamsasenjan, K., & Akbarzadeh, A. (2016) · Artificial Cells Nanomedicine and Biotechnology · doi:10.3109/21691401.2015.1129620 · Cited by 125 · see citing works

Scaffold strategies for modulating immune microenvironment during bone regeneration

He, J., Chen, G., Liu, M., Xu, Z., Chen, H., Yang, L., & Lv, Y. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.110411 · Cited by 127 · see citing works

Mesenchymal Stem Cells Induce an Inflammatory Response After Intravenous Infusion

Hoogduijn, M. J., Rhijn, M. R.-V., Engela, A. U., Korevaar, S. S., Mensah, F., Franquesa, M., de Bruin, R. W. F., Betjes, M. G. H., Weimar, W., & Baan, C. C. (2013) · Stem Cells and Development · doi:10.1089/scd.2013.0193 · Cited by 121 · see citing works

Increased Paracrine Immunomodulatory Potential of Mesenchymal Stromal Cells in Three-Dimensional Culture

Follin, B., Juhl, M., Cohen, S., Pedersen, A. E., Kastrup, J., & Ekblond, A. (2016) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2015.0532 · Cited by 113 · see citing works

Allogeneic mesenchymal stem cell transplantation for lupus nephritis patients refractory to conventional therapy

Gu, F., Wang, D., Zhang, H., Feng, X., Gilkeson, G. S., Shi, S., & Sun, L. (2014) · Clinical Rheumatology · doi:10.1007/s10067-014-2754-4 · Cited by 112 · see citing works

Long-Lasting Effects of Human Mesenchymal Stem Cell Systemic Administration on Pain-Like Behaviors, Cellular, and Biomolecular Modifications in Neuropathic Mice

Siniscalco, D., Giordano, C., Galderisi, U., Luongo, L., de Novellis, V., Rossi, F., & Maione, S. (2011) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2011.00079 · Cited by 112 · see citing works

Autologous Bone Marrow Mononuclear Cell Therapy for Autism: An Open Label Proof of Concept Study

Sharma, A., Gokulchandran, N., Sane, H., Nagrajan, A., Paranjape, A., Kulkarni, P., Shetty, A., Mishra, P., Kali, M., Biju, H., et al. (2013) · Stem Cells International · doi:10.1155/2013/623875 · Cited by 110 · see citing works

Immune characterization of mesenchymal stem cells in human umbilical cord Wharton’s jelly and derived cartilage cells

Liu, S., Yuan, M., Hou, K., Zhang, L., Zheng, X., Zhao, B., Sui, X., Xu, W., Lu, S., & Guo, Q. (2012) · Cellular Immunology · doi:10.1016/j.cellimm.2012.06.010 · Cited by 108 · see citing works

Immunomodulatory Effect of MSC on B Cells Is Independent of Secreted Extracellular Vesicles

Carreras‐Planella, L., Tortajada, M., Borràs, F. E., & Franquesa, M. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01288 · Cited by 106 · see citing works

Toward Development of iMesenchymal Stem Cells for Immunomodulatory Therapy

de Witte, S. F. H., Franquesa, M., Baan, C. C., & Hoogduijn, M. J. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00648 · Cited by 103 · see citing works

The potential use of mesenchymal stem cells in hematopoietic stem cell transplantation

Kim, E., Kim, N., & Cho, S. (2013) · Experimental & Molecular Medicine · doi:10.1038/emm.2013.2 · Cited by 102 · see citing works

Insights into inflammatory priming of mesenchymal stromal cells: functional biological impacts

Najar, M., Krayem, M., Merimi, M., Burny, A., Meuleman, N., Bron, D., Raicevic, G., & Lagneaux, L. (2018) · Inflammation Research · doi:10.1007/s00011-018-1131-1 · Cited by 100 · see citing works

Immune regulatory targets of mesenchymal stromal cell exosomes/small extracellular vesicles in tissue regeneration

Toh, W. S., Zhang, B., Lai, R. C., & Lim, S. K. (2018) · Cytotherapy · doi:10.1016/j.jcyt.2018.09.008 · Cited by 98 · see citing works

The role of TNF-α in the fate regulation and functional reprogramming of mesenchymal stem cells in an inflammatory microenvironment

Li, W., Liu, Q., Shi, J., Xu, X. M., & Xu, J. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1074863 · Cited by 104 · see citing works

Human adipose-tissue derived mesenchymal stem cells induce functional de-novo regulatory T cells with methylated FOXP3 gene DNA

Engela, A. U., Hoogduijn, M. J., Boer, K., Litjens, N. H. R., Betjes, M. G. H., Weimar, W., & Baan, C. C. (2013) · Clinical & Experimental Immunology · doi:10.1111/cei.12120 · Cited by 92 · see citing works

Membrane particles generated from mesenchymal stromal cells modulate immune responses by selective targeting of pro-inflammatory monocytes

Gonçalves, F. D. C., Luk, F., Korevaar, S. S., Bouzid, R., Paz, A. H. D. R., López‐Iglesias, C., Baan, C. C., Merino, A. M., & Hoogduijn, M. J. (2017) · Scientific Reports · doi:10.1038/s41598-017-12121-z · Cited by 87 · see citing works

Therapeutic Mesenchymal Stromal Cells for Immunotherapy and for Gene and Drug Delivery

Almeida-Porada, G. D., Atala, A., & Porada, C. D. (2020) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2020.01.005 · Cited by 88 · see citing works

miRNA Control of Tissue Repair and Regeneration

Sen, C. K., & Ghatak, S. (2015) · American Journal Of Pathology · doi:10.1016/j.ajpath.2015.04.001 · Cited by 87 · see citing works

On the interactions between mesenchymal stem cells and regulatory T cells for immunomodulation in transplantation

Engela, A. U., Baan, C. C., Dor, F. J. M. F., Weimar, W., & Hoogduijn, M. J. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00126 · Cited by 82 · see citing works

Aging of bone marrow– and umbilical cord–derived mesenchymal stromal cells during expansion

de Witte, S. F. H., Lambert, E. E., Merino, A. M., Strini, T., Douben, H., O’Flynn, L., Elliman, S. J., de Klein, A., Newsome, P. N., Baan, C. C., et al. (2017) · Cytotherapy · doi:10.1016/j.jcyt.2017.03.071 · Cited by 81 · see citing works

Mechanisms of Immune Suppression Utilized by Canine Adipose and Bone Marrow-Derived Mesenchymal Stem Cells

Chow, L., Johnson, V., Coy, J. W., Regan, D. P., & DOW, S. W. (2016) · Stem Cells and Development · doi:10.1089/scd.2016.0207 · Cited by 78 · see citing works

Partnership between platelet-rich plasma and mesenchymal stem cells: in vitro experience

Rubio‐Azpeitia, E. (2014) · Muscles Ligaments and Tendons Journal · doi:10.11138/mltj/2014.4.1.052 · Cited by 76 · see citing works

Mesenchymal stem cells for the treatment and prevention of graft-versus-host disease: experiments and practice

Kim, N., Im, K.-I., Lim, J.-Y., Jeon, E.-J., Nam, Y.-S., Kim, E., & Cho, S. (2013) · Annals of Hematology · doi:10.1007/s00277-013-1796-z · Cited by 71 · see citing works

Bottlenecks in the Efficient Use of Advanced Therapy Medicinal Products Based on Mesenchymal Stromal Cells

Escacena, N., Quesada-Hernández, E., Capilla‐González, V., Soria, B., & Hmadcha, A. (2015) · Stem Cells International · doi:10.1155/2015/895714 · Cited by 71 · see citing works

Enhanced immunoregulation of mesenchymal stem cells by IL-10-producing type 1 regulatory T cells in collagen-induced arthritis

Lim, J.-Y., Im, K.-I., Lee, E., Kim, N., Nam, Y.-S., Jeon, Y., & Cho, S. (2016) · Scientific Reports · doi:10.1038/srep26851 · Cited by 71 · see citing works

Allogeneic Mesenchymal Stem Cell Transplantation in Dogs with Keratoconjunctivitis Sicca

Bittencourt, M. K. W., Barros, M. A., Martins, J. F. P., de Vasconcellos, J. P. C., de Morais, B. P., Pompéia, C., Bittencourt, M. D., Evangelho, K. D. S., Kerkis, I., & Wenceslau, C. V. (2016) · Cell Medicine · doi:10.3727/215517916x693366 · Cited by 70 · see citing works

Preconditioning strategies for improving the survival rate and paracrine ability of mesenchymal stem cells in acute kidney injury

Zhao, L., Hu, C., Zhang, P., Jiang, H., & Chen, J. (2018) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14035 · Cited by 70 · see citing works

Optimization of Culture Conditions for the Expansion of Umbilical Cord-Derived Mesenchymal Stem or Stromal Cell-Like Cells Using Xeno-Free Culture Conditions

Hatlapatka, T., Moretti, P., Lavrentieva, A. V., Hass, R., Marquardt, N., Jacobs, R., & Kasper, C. (2010) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2010.0406 · Cited by 67 · see citing works

Interaction between Adipose Tissue-Derived Mesenchymal Stem Cells and Regulatory T-Cells

Engela, A. U., Baan, C. C., Peeters, A. M. A., Weimar, W., & Hoogduijn, M. J. (2013) · Cell Transplantation · doi:10.3727/096368912x636984 · Cited by 69 · see citing works

Partnership between platelet-rich plasma and mesenchymal stem cells: in vitro experience

Rubio‐Azpeitia, E., & Andı́a, I. (2019) · Muscles Ligaments and Tendons Journal · doi:10.32098/mltj.01.2014.10 · Cited by 67 · see citing works

Improving Immunotherapy Through Glycodesign

Buettner, M. J., Shah, S. R., Saeui, C. T., Ariss, R., & Yarema, K. J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02485 · Cited by 66 · see citing works

Prospects of Stem Cell Therapy in Osteoarthritis

Roberts, S., Genever, P. G., McCaskie, A. W., & Bari, C. D. (2011) · Regenerative Medicine · doi:10.2217/rme.11.21 · Cited by 65 · see citing works

The Stem Cell Niche Should be a Key Issue for Cell Therapy in Regenerative Medicine

Becerra, J., Santos‐Ruiz, L., Andrades, J. A., & Marí‐Beffa, M. (2010) · Stem Cell Reviews and Reports · doi:10.1007/s12015-010-9195-5 · Cited by 62 · see citing works

Cost-Effective, Safe, and Personalized Cell Therapy for Critical Limb Ischemia in Type 2 Diabetes Mellitus

Soria-Juan, B., Escacena, N., Capilla‐González, V., Aguilera, Y., Llanos, L., Tejedo, J. R., Bedoya, F. J., Juan, V., de la Cuesta, A., Ruiz-Salmeron, R. J., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01151 · Cited by 61 · see citing works

Strategies to improve the immunosuppressive properties of human mesenchymal stem cells

Lee, M. W., Ryu, S., Kim, D. S., Sung, K. W., Koo, H. H., & Yoo, K. H. (2015) · Stem Cell Research & Therapy · doi:10.1186/s13287-015-0178-y · Cited by 61 · see citing works

Autism Spectrum Disorders: Is Mesenchymal Stem Cell Personalized Therapy the Future?

Siniscalco, D., Sapone, A., Cirillo, A., Giordano, C., Maione, S., & Antonucci, N. (2012) · BioMed Research International · doi:10.1155/2012/480289 · Cited by 61 · see citing works

Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis—Masters of Survival and Clonality?

Pleyer, L., Valent, P., & Greil, R. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17071009 · Cited by 60 · see citing works

The Immunomodulatory Potential of Wharton’s Jelly Mesenchymal Stem/Stromal Cells

Paladino, F. V., Rodrigues, J. D. M., da Silva, A., & Goldberg, A. C. (2019) · Stem Cells International · doi:10.1155/2019/3548917 · Cited by 60 · see citing works

Molecular Basis beyond Interrelated Bone Resorption/Regeneration in Periodontal Diseases: A Concise Review

Sadek, K. M., Moshy, S. E., Radwan, I. A., Rady, D., Abbass, M. M. S., El‐Rashidy, A. A., Dörfer, C. E., & El‐Sayed, K. M. F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054599 · Cited by 62 · see citing works

Adipose tissue derived stromal stem cell therapy in murine C on A ‐derived hepatitis is dependent on myeloid‐lineage and CD 4 + T ‐cell suppression

Higashimoto, M., Sakai, Y., Takamura, M., Usui, S., Nasti, A., Yoshida, K., Seki, A., Komura, T., Honda, M., Wada, T., et al. (2013) · European Journal of Immunology · doi:10.1002/eji.201343531 · Cited by 56 · see citing works

Monocyte‐derived extracellular vesicles stimulate cytokine secretion and gene expression of matrix metalloproteinases by mesenchymal stem/stromal cells

Gebraad, A., Kornilov, R., Kaur, S., Miettinen, S., Haimi, S. P., Peltoniemi, H. H., Mannerström, B., & Seppänen‐Kaijansinkko, R. (2018) · FEBS Journal · doi:10.1111/febs.14485 · Cited by 56 · see citing works

Mesenchymal stem cells decrease splenocytes apoptosis in a sepsis experimental model

Pedrazza, L., Lunardelli, A., Luft, C., Cruz, C. U., de Mesquita, F. C., Bitencourt, S., Nunes, F. B., & de Oliveira, J. R. (2014) · Inflammation Research · doi:10.1007/s00011-014-0745-1 · Cited by 55 · see citing works

Mesenchymal stem cells derived from adipose tissue are not affected by renal disease

Rhijn, M. R.-V., Reinders, M. E. J., de Klein, A., Douben, H., Korevaar, S. S., Mensah, F., Dor, F. J. M. F., IJzermans, J. N. M., Betjes, M. G. H., Baan, C. C., et al. (2012) · Kidney International · doi:10.1038/ki.2012.187 · Cited by 55 · see citing works

Double Allogenic Mesenchymal Stem Cells Transplantations Could Not Enhance Therapeutic Effect Compared with Single Transplantation in Systemic Lupus Erythematosus

Wang, D., Akiyama, K., Zhang, H., Yamaza, T., Li, X., Feng, X., Wang, H., Hua, B., Liu, B., Xu, H., et al. (2012) · Clinical and Developmental Immunology · doi:10.1155/2012/273291 · Cited by 54 · see citing works

Are mesenchymal stromal cells immune cells?

Hoogduijn, M. J. (2015) · Arthritis Research & Therapy · doi:10.1186/s13075-015-0596-3 · Cited by 54 · see citing works

Extracellular vesicles from mesenchymal stem cells prevent contact hypersensitivity through the suppression of Tc1 and Th1 cells and expansion of regulatory T cells

Guo, L., Lai, P., Wang, Y., Huang, T., Chen, X., Luo, C., Geng, S., Huang, X., Wu, S., Ling, W., et al. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.05.048 · Cited by 54 · see citing works

Extracellular Vesicles as Therapeutic Tools for the Treatment of Chronic Wounds

Bray, E. R., Oropallo, A., Grande, D. A., Kirsner, R. S., & Badiavas, E. V. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13101543 · Cited by 56 · see citing works

Adipose Tissue-Derived Mesenchymal Stem Cells Exert In Vitro Immunomodulatory and Beta Cell Protective Functions in Streptozotocin-Induced Diabetic Mice Model

Rahavi, H., Hashemi, S. M., Soleimani, M., Mohammadi, J., & Tajik, N. (2015) · Journal of Diabetes Research · doi:10.1155/2015/878535 · Cited by 52 · see citing works

Inducible HGF-secreting Human Umbilical Cord Blood-derived MSCs Produced via TALEN-mediated Genome Editing Promoted Angiogenesis

Chang, H., Kim, P., Cho, H., Yum, S., Choi, Y., Son, Y., Lee, D., Kang, I., Kang, K., Jang, G., et al. (2016) · Molecular Therapy · doi:10.1038/mt.2016.120 · Cited by 52 · see citing works

A Small-Molecule Screen for Enhanced Homing of Systemically Infused Cells

Levy, O., Mortensen, L. J., Boquet, G., Tong, Z., Perrault, C., Benhamou, B., Zhang, J., Stratton, T., Han, E., Safaee, H., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.01.057 · Cited by 50 · see citing works

Effect of Arthritic Synovial Fluids on the Expression of Immunomodulatory Factors by Mesenchymal Stem Cells: An Explorative in vitro Study

Leijs, M. J. C., van Buul, G. M., Lubberts, E., Bos, P. K., Verhaar, J. A. N., Hoogduijn, M. J., & van Osch, G. J. V. M. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00231 · Cited by 50 · see citing works

Emerging roles of mesenchymal stem cell therapy in patients with critical limb ischemia

Shirbaghaee, Z., Hassani, M., Keshel, S. H., & Soleimani, M. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-03148-9 · Cited by 49 · see citing works

Wound-Healing Effects of Mesenchymal Stromal Cell Secretome in the Cornea and the Role of Exosomes

An, S., Anwar, K. N., Ashraf, M. J., Lee, H., Jung, R., Koganti, R., Ghassemi, M., & Djalilian, A. R. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15051486 · Cited by 48 · see citing works

Tolerance in Organ Transplantation: From Conventional Immunosuppression to Extracellular Vesicles

Tortajada, M., Lauzurica, R., & Borràs, F. E. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00416 · Cited by 47 · see citing works

The Use of Cocultured Mesenchymal Stem Cells with Tendon-Derived Stem Cells as a Better Cell Source for Tendon Repair

Wu, T., Yang, L., Wang, B., Sun, Y., Xu, J., Lee, W., Xu, L., Zhang, J., & Li, G. (2016) · Tissue Engineering Part A · doi:10.1089/ten.tea.2016.0248 · Cited by 46 · see citing works

Interaction of multipotent mesenchymal stromal and immune cells: Bidirectional effects

Andreeva, E. R., Бобылева, П. И., Gornostaeva, A. N., & Buravkova, L. B. (2017) · Cytotherapy · doi:10.1016/j.jcyt.2017.07.001 · Cited by 45 · see citing works

Suppression of T cells by mesenchymal and cardiac progenitor cells is partly mediated via extracellular vesicles

van den Akker, F., Vrijsen, K. R., Deddens, J. C., Buikema, J. W., Mokrý, M., Laake, L. W. V., Doevendans, P. A., & Sluijter, J. P. G. (2018) · Heliyon · doi:10.1016/j.heliyon.2018.e00642 · Cited by 46 · see citing works

Human embryonic stem cell-derived mesenchymal stromal cells ameliorate collagen-induced arthritis by inducing host-derived indoleamine 2,3 dioxygenase

Gonzalo-Gil, E., Pérez-Lorenzo, M. J., Galindo-Izquierdo, M., de la Guardia, R. D., López‐Millán, B., Bueno, C., Menéndez, P. R., Pablos, J. L., & Criado, G. (2016) · Arthritis Research & Therapy · doi:10.1186/s13075-016-0979-0 · Cited by 45 · see citing works

Biotechnological and biomedical applications of mesenchymal stem cells as a therapeutic system

Rahimzadeh, A., Mirakabad, F. S. T., Movassaghpour, A. A., Shamsasenjan, K., Kariminekoo, S., Talebi, M., Shekari, A., Zeighamian, V., Ghalhar, M. G., & Akbarzadeh, A. (2014) · Artificial Cells Nanomedicine and Biotechnology · doi:10.3109/21691401.2014.968823 · Cited by 44 · see citing works

Etanercept-Synthesising Mesenchymal Stem Cells Efficiently Ameliorate Collagen-Induced Arthritis

Park, N., Rim, Y. A., Jung, H., Kim, J., Yi, H., Kim, Y., Jang, Y., Jung, S. M., Lee, J. J., Kwok, S., et al. (2017) · Scientific Reports · doi:10.1038/srep39593 · Cited by 42 · see citing works

Human Mesenchymal Stem Cell Secretome Driven T Cell Immunomodulation Is IL-10 Dependent

Shephard, M. T., Merkhan, M. M., & Forsyth, N. R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113596 · Cited by 42 · see citing works

Stem cell therapy emerging as the key player in treating type 1 diabetes mellitus

Vanikar, A. V., Trivedi, H. L., & Thakkar, U. G. (2016) · Cytotherapy · doi:10.1016/j.jcyt.2016.06.006 · Cited by 42 · see citing works

Immunomodulatory influence of bone marrow-derived mesenchymal stem cells on neuroinflammation in astrocyte cultures

Schäfer, S., Calas, A.-G., Vergouts, M., & Hermans, E. (2012) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2012.04.018 · Cited by 42 · see citing works

Effect on Ligament Marker Expression by Direct-Contact Co-culture of Mesenchymal Stem Cells and Anterior Cruciate Ligament Cells

Canseco, J. A., Kojima, K., Penvose, A. R., Ross, J. D., Obokata, H., Gomoll, A. H., & Vacanti, C. A. (2012) · Tissue Engineering Part A · doi:10.1089/ten.tea.2012.0030 · Cited by 41 · see citing works

Rat Mesenchymal Stromal Cells Inhibit T Cell Proliferation but Not Cytokine Production Through Inducible Nitric Oxide Synthase

Zinöcker, S., & Vaage, J. T. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00062 · Cited by 41 · see citing works

Therapeutic Efficacy of Cord Blood-Derived Mesenchymal Stromal Cells for the Prevention of Acute Graft-Versus-Host Disease in a Xenogenic Mouse Model

Gregoire-Gauthier, J., Selleri, S., Fontaine, F., Dieng, M. M., Patey, N., Despars, G., Beausejour, C. M., & Haddad, É. (2011) · Stem Cells and Development · doi:10.1089/scd.2011.0413 · Cited by 41 · see citing works

The immunomodulatory function of equine MSCs is enhanced by priming through an inflammatory microenvironment or TLR3 ligand

Cassano, J. M., Schnabel, L. V., Goodale, M. B., & Fortier, L. A. (2017) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2017.10.003 · Cited by 41 · see citing works

High-risk corneal allografts: A therapeutic challenge

Tian, Y., Rajendran, V., Griffith, M., Forrester, J. V., & Kuffová, L. (2016) · World Journal of Transplantation · doi:10.5500/wjt.v6.i1.10 · Cited by 40 · see citing works

Interleukin‐12 modulates the immunomodulatory properties of human periodontal ligament cells

Ayuthaya, B. I. N., Satravaha, P., & Pavasant, P. (2016) · Journal of Periodontal Research · doi:10.1111/jre.12421 · Cited by 40 · see citing works

Priming with Toll-like receptor 3 agonist or interferon-gamma enhances the therapeutic effects of human mesenchymal stem cells in a murine model of atopic dermatitis

Park, A., Park, H., Yoon, J., Kang, D., Kang, M.-H., Park, Y.-Y., Suh, N., & Yu, J. (2019) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1164-6 · Cited by 39 · see citing works

Mesenchymal stem cell therapy in proteoglycan induced arthritis

Swart, J. F., de Roock, S., Hofhuis, F. M., Rozemuller, H., van den Broek, T., Moerer, P., Broere, F., van Wijk, F., Kuis, W., Prakken, B. J., et al. (2014) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2013-204147 · Cited by 37 · see citing works

Secretome within the bone marrow microenvironment: A basis for mesenchymal stem cell treatment and role in cancer dormancy

Eltoukhy, H. S., Sinha, G., Moore, C. A., Gergues, M., & Rameshwar, P. (2018) · Biochimie · doi:10.1016/j.biochi.2018.05.018 · Cited by 36 · see citing works

Potential benefits of allogeneic bone marrow mesenchymal stem cells for wound healing

Badiavas, A. R., & Badiavas, E. V. (2011) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2011.606212 · Cited by 36 · see citing works

Interface Oral Health Science 2016

Takahashi, N., Sasaki, K., & Suzuki, O. (2016) · Springer eBooks · doi:10.1007/978-981-10-1560-1 · Cited by 36 · see citing works

A new strategy for intervertebral disc regeneration: The synergistic potential of mesenchymal stem cells and their extracellular vesicles with hydrogel scaffolds

Zhao, Y., Dong, H., Xia, Q., Wang, Y., Zhu, L., Hu, Z., Xia, J., Mao, Q., Weng, Z., Yi, J., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116238 · Cited by 35 · see citing works

hMSCs suppress neutrophil-dominant airway inflammation in a murine model of asthma

Hong, G. H., Kwon, H., Lee, K. Y., Ha, E., Moon, K., Kim, S. W., Oh, W., Kim, T., Moon, H., & Cho, Y. S. (2017) · Experimental & Molecular Medicine · doi:10.1038/emm.2016.135 · Cited by 34 · see citing works

Combinatory Effects of Bone Marrow-Derived Mesenchymal Stem Cells and Indomethacin on Adjuvant-Induced Arthritis in Wistar Rats: Roles of IL-1β, IL-4, Nrf-2, and Oxidative Stress

Ahmed, E. A., Ahmed, O. M., Fahim, H. I., Mahdi, E. A., Ali, T. M., Elesawy, B. H., & Ashour, M. B. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/8899143 · Cited by 33 · see citing works

Allogeneic adipose-derived mesenchymal stromal cell transplantation for refractory lupus nephritis: Results of a phase I clinical trial

Ranjbar, A., Hassanzadeh, H., Jahandoust, F., Miri, R., Bidkhori, H. R., Monzavi, S. M., Moussavi, N. S., Matin, M. M., & Shariati‐Sarabi, Z. (2021) · Current Research in Translational Medicine · doi:10.1016/j.retram.2021.103324 · Cited by 34 · see citing works

The Immune Response to Allogeneic Differentiated Mesenchymal Stem Cells in the Context of Bone Tissue Engineering

Kiernan, C. H., Wolvius, E. B., Brama, P. A. J., & Farrell, E. (2017) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2017.0175 · Cited by 34 · see citing works

Overcoming biological barriers to improve solid tumor immunotherapy

Ukidve, A., Cu, K., Kumbhojkar, N., Lahann, J., & Mitragotri, S. (2021) · Drug Delivery and Translational Research · doi:10.1007/s13346-021-00923-8 · Cited by 33 · see citing works

Mesenchymal stem cell therapy targeting mitochondrial dysfunction in acute kidney injury

Zhao, L., Hu, C., Zhang, P., Jiang, H., & Chen, J. (2019) · Journal of Translational Medicine · doi:10.1186/s12967-019-1893-4 · Cited by 31 · see citing works

Therapeutic Potential of Mesenchymal Stem Cells for Oral and Systemic Diseases

Kim, R. H., Mehrazarin, S., & Kang, M. (2012) · Dental Clinics of North America · doi:10.1016/j.cden.2012.05.006 · Cited by 31 · see citing works

Small extracellular vesicles-shuttled miR-23a-3p from mesenchymal stem cells alleviate renal fibrosis and inflammation by inhibiting KLF3/STAT3 axis in diabetic kidney disease

Li, Q., Liu, J., Su, R., Zhen, J., Liu, X., & Liu, G. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112667 · Cited by 30 · see citing works

Perspectives on the Use of Stem Cells for Autism Treatment

Siniscalco, D., Bradstreet, J. J., Sych, N., & Antonucci, N. (2013) · Stem Cells International · doi:10.1155/2013/262438 · Cited by 30 · see citing works

A Novel Therapeutic Approach Using Mesenchymal Stem Cells to Protect Against Mycobacterium abscessus

Kim, J.-S., Cha, S., Kim, W. S., Han, S. J., Bin, S., Kim, H. M., Kwon, K. W., Kim, S. J., Choi, H.-H., Lee, J., et al. (2016) · Stem Cells · doi:10.1002/stem.2353 · Cited by 30 · see citing works

Mesenchymal stromal cell based therapies for the treatment of immune disorders: recent milestones and future challenges

Gonzalez‐Pujana, A., Igartua, M., Santos‐Vizcaíno, E., & Hernández, R. M. (2020) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2020.1714587 · Cited by 34 · see citing works

Mesenchymal stem cell therapy for the treatment of inflammatory diseases: Challenges, opportunities, and future perspectives

Regmi, S., Pathak, S., Kim, J. O., Yong, C. S., & Jeong, J. (2019) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2019.04.002 · Cited by 316 · see citing works

Immunomodulatory properties of mesenchymal stem cells and their therapeutic applications

Yi, T., & Song, S. U. (2012) · Archives of Pharmacal Research · doi:10.1007/s12272-012-0202-z · Cited by 284 · see citing works

Immunomodulatory mechanisms of mesenchymal stem cells and their therapeutic applications

Lee, D. K., & Song, S. U. (2017) · Cellular Immunology · doi:10.1016/j.cellimm.2017.08.009 · Cited by 68 · see citing works

Mesenchymal stem cells: Immunomodulatory capability and clinical potential in immune diseases

Zhao, Q., Ren, H., & Han, Z. (2015) · Journal of Cellular Immunotherapy · doi:10.1016/j.jocit.2014.12.001 · Cited by 303 · see citing works