The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Adolescents With Major Depression Demonstrate Increased Amygdala Activation
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In the RDoC matrix, it is also evident that generalized and social anxiety and depression symptomatology are linked to dysfunction in the same neurocircuitry, such as sustained limbic hyperreactivity (18–20) and reduced adaptive flexibility of the default mode network (DMN) (20–22).”
From Feasibility and preliminary efficacy of a novel RDoC-based treatment program for adolescent depression: "Training for Awareness Resilience and Action" (TARA)-A pilot study (2017) · cites this paper as [18]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Previous and current fMRI studies from our group and others consistently show that depressed adolescents demonstrate increased hyperactivation of the amygdala, a key limbic structure involved in emotion generative processing (18) and aberrant functional connectivity between the amygdala and other emotional regulation areas (19, 23, 24).”
From Feasibility and preliminary efficacy of a novel RDoC-based treatment program for adolescent depression: "Training for Awareness Resilience and Action" (TARA)-A pilot study (2017) · cites this paper as [18]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798
AFNI: Software for analysis and visualization of functional magnetic resonance neuroimages
Cox, R. W. (1996) · Computers and Biomedical Research · doi:10.1006/cbmr.1996.0014 · Cited by 10,913
Co-planar stereotaxic atlas of the human brain
Laitinen, L. (1989) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(89)90128-5 · Cited by 7,565
Talairach, J., Tournoux, P., & Rayport, M. (1988) · Thieme eBooks · Cited by 5,058
A Children's Global Assessment Scale (CGAS)
Shaffer, D. (1983) · Archives of General Psychiatry · doi:10.1001/archpsyc.1983.01790100074010 · Cited by 3,716
SHAFFER, D., FISHER, P., LUCAS, C. P., DULCAN, M. K., & SCHWAB-STONE, M. E. (2000) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200001000-00014 · Cited by 3,505
Serotonin transporter genetic variation and the response of the human amygdala.
Hariri, A. R., Mattay, V. S., Tessitore, A., Kolachana, B., Fera, F., Goldman, D., Egan, M. F., & Weinberger, D. R. (2002) · Science · doi:10.1126/science.1071829 · Cited by 2,340
The Multidimensional Anxiety Scale for Children (MASC): factor structure, reliability, and validity
MARCH, J. S., PARKER, J. D. A., SULLIVAN, K., STALLINGS, P., & CONNERS, C. K. (1997) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199704000-00019 · Cited by 2,236
Childhood and adolescent depression: a review of the past 10 years, Part I
BIRMAHER, B., RYAN, N. D., WILLIAMSON, D. E., BRENT, D. A., KAUFMAN, J., DAHL, R. E., PEREL, J., & NELSON, B. (1996) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199611000-00011 · Cited by 2,076
Flagged first, then by citations
Cited by
Sorted by citations
Items 101–176 of 176
Hodges, T. E., Lee, G. Y., Noh, S. H., & Galea, L. A. M. (2022) · Neurobiology of Stress · doi:10.1016/j.ynstr.2022.100458 · Cited by 21
Transcranial direct current stimulation: considerations for research in adolescent depression
Lee, J. C., Lewis, C. P., Daskalakis, Z. J., & Croarkin, P. E. (2017) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2017.00091 · Cited by 22
Tymofiyeva, O., Henje, E., Yuan, J. P., Huang, C., Connolly, C. G., Ho, T. C., Bhandari, S., Parks, K. C., Sipes, B. S., Yang, T. T., et al. (2020) · NeuroImage Clinical · doi:10.1016/j.nicl.2020.102521 · Cited by 28
Self-citationKaya, M., & McCabe, C. (2019) · Brain Sciences · doi:10.3390/brainsci9050104 · Cited by 23
Nikolova, Y. S., Iruku, S. P., Lin, C., Drabant, E. M., Puralewski, R., French, B. J., Hariri, A. R., & Sibille, E. L. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.01377 · Cited by 21
Serio, B., Köhler, R., Ye, F., Lichenstein, S. D., & Yip, S. W. (2022) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2022.101182 · Cited by 21
Psilocybin’s Potential Mechanisms in the Treatment of Depression: A Systematic Review
Lee, H. J., Tsang, V. W. L., Chai, B. S., Lin, M. C., Howard, A. K., Uy, C. E., & Elefante, J. (2023) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2023.2223195 · Cited by 21
Waller, J. A., Tamm, J. A., Abdourahman, A., Pehrson, A. L., Li, Y., Cajina, M., & Sánchez, C. (2017) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2016.11.014 · Cited by 20
Predictions of children’s emotionality from evolutionary and epigenetic hypotheses
Hill, J., Pickles, A. R., Wright, N., Braithwaite, E., & Sharp, H. M. (2019) · Scientific Reports · doi:10.1038/s41598-019-39513-7 · Cited by 22
How do antidepressants influence the BOLD signal in the developing brain?
Harris, J. J., & Reynell, C. (2016) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2016.12.003 · Cited by 20
Hagan, C. C., Graham, J. M., Widmer, B., Holt, R., Ooi, C., van Nieuwenhuizen, A. O., Fonagy, P., Reynolds, S. A., Target, M., Kelvin, R. G., et al. (2013) · BMC Psychiatry · doi:10.1186/1471-244x-13-247 · Cited by 18
Thai, M., Başgöze, Z., Klimes‐Dougan, B., Mueller, B. A., Fiecas, M. J. A., Lim, K. O., Albott, C. S., & Cullen, K. R. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00820 · Cited by 21
Gray space and default mode network-amygdala connectivity
Harris, J. C., Liuzzi, M. T., Cardenas‐Iniguez, C., Larson, C. L., & Lisdahl, K. M. (2023) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2023.1167786 · Cited by 18
Uliana, D. L., Gomes, F. V., & Grace, A. A. (2020) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2020.04.004 · Cited by 19
Wang, S., Liu, X., Shi, W., Qian, Q., Zhang, G., Li, Y., Cong, B., & Zuo, M. (2021) · Analytical Cellular Pathology · doi:10.1155/2021/8388527 · Cited by 16
Laeken, N. V., Pauwelyn, G., Dockx, R., Descamps, B., Brans, B. T., Peremans, K. Y., Baeken, C., Goethals, I., Vanhove, C., & Vos, F. D. (2018) · Journal of Neural Transmission · doi:10.1007/s00702-018-1899-8 · Cited by 18
Batabyal, A. (2023) · Journal of Experimental Biology · doi:10.1242/jeb.245851 · Cited by 17
Zhu, J., Zhang, W., Chen, Y., & Teicher, M. H. (2024) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2024.01.014 · Cited by 14
Uddin, M., Jansen, S., & Telzer, E. H. (2017) · BioEssays · doi:10.1002/bies.201600194 · Cited by 25
Self‐Regulation and Developmental Psychopathology: Experiential Canalization of Brain and Behavior
Blair, C., Raver, C. C., & Finegood, E. D. (2016) · Wiley eBooks · doi:10.1002/9781119125556.devpsy213 · Cited by 16
Hu, C., Jiang, W., Huang, J., Lin, J., Huang, J., Wang, M., Xie, J. M., & Yuan, Y. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1228260 · Cited by 12
Fragility of reward vs antifragility of defense brain systems in drug dependence
Prospero-Garcia, O. E., Ruiz‐Contreras, A. E., Morelos, J. C., Herrera-Solís, A., & Méndez‐Díaz, M. (2021) · Social Neuroscience · doi:10.1080/17470919.2021.1876759 · Cited by 12
Bauer, E., Wilson, K. A., Phan, K. L., Shankman, S. A., & MacNamara, A. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2022.08.009 · Cited by 12
Ekbäck, E., Granåsen, G., Svärling, R., Blomqvist, I., & Henje, E. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.674583 · Cited by 11
Song, D., Liu, P., Ma, X., Chang, D., & Wang, Z. (2024) · medRxiv · doi:10.1101/2024.04.26.24306327 · Cited by 10
Bonduelle, S. L. B., Raedt, R. D., Braet, C., Campforts, E., & Baeken, C. (2023) · Journal of Experimental Child Psychology · doi:10.1016/j.jecp.2023.105728 · Cited by 9
Goldstein‐Piekarski, A. N., & Williams, L. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813333-0.00021-4 · Cited by 10
Amygdala response to emotional faces in adolescents with persistent post-concussion symptoms
Bohorquez‐Montoya, L., España, L. Y., Nader, A. M., Furger, R. E., Mayer, A. R., & Meier, T. B. (2020) · NeuroImage Clinical · doi:10.1016/j.nicl.2020.102217 · Cited by 13
Mu, J., Ma, L., Ding, D., Ma, X., Li, P., Li, R., Zhang, M., & Liu, J. (2020) · Brain Imaging and Behavior · doi:10.1007/s11682-020-00376-6 · Cited by 9
Fujita, S., Yoshida, S., Matsuki, T., Jaiswal, M. K., & Seki, K. (2020) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000605 · Cited by 9
Chaplin, T. M., Curby, T. W., Gonçalves, S. F., Kisner, M. A., Niehaus, C. E., & Thompson, J. C. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114499 · Cited by 8
Zhang, F., Liu, W., Zheng, Y., Liu, C., Hu, Y. G., Chen, H., Tang, X., Wei, Y., Zhang, T., Wang, J., et al. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.01.011 · Cited by 8
Schumacher, A., Muha, J., Campisi, S. C., Bradley-Ridout, G., Lee, A. C. H., & Korczak, D. J. (2024) · Neuropsychobiology · doi:10.1159/000538060 · Cited by 9
Maynard, M. L., Quenneville, S., Hinves, K., Talwar, V., & Bosacki, S. (2022) · Adolescents · doi:10.3390/adolescents3010003 · Cited by 10
Wu, Y.-C., Yu, H., Yen, C., Yeh, Y., Jian, C.-R., Lin, C.-W., & Lin, I. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.01.020 · Cited by 7
Bonduelle, S. L. B., Chen, Q., Wu, G., Braet, C., Raedt, R. D., & Baeken, C. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.673805 · Cited by 7
A Systems Neuroscience Approach to the Pathophysiology of Pediatric Mood and Anxiety Disorders
Tseng, W., Leibenluft, E., & Brotman, M. A. (2013) · Current topics in behavioral neurosciences · doi:10.1007/7854_2013_252 · Cited by 8
Ekbäck, E., Rådmark, L., Molin, J., Strömbäck, M., Midgley, N., & Henje, E. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1393066 · Cited by 9
Dai, Q., Li, M., Wang, Z., Xu, Q., Zhang, X., & Tao, L. (2024) · Healthcare · doi:10.3390/healthcare12242539 · Cited by 5
Interplay Between the Physical Environment and the Human Brain: A Review of MRI Research
Beyer, M., Sudimac, S., Steininger, M. O., & Kühn, S. (2024) · Springer eBooks · doi:10.1007/978-3-031-64699-7_3 · Cited by 8
Schizophrenia and Affective Disorders
Picker, J. D. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-383834-6.00117-8 · Cited by 5
Ladouceur, C. D. (2016) · Santé mentale au Québec · doi:10.7202/1036965ar · Cited by 6
Psychiatric morbidity in patients with rheumatoid juvenile arthritis
Reda, M., Hosny, E., & AbuSenna, H. (2011) · Middle East Current Psychiatry · doi:10.1097/01.xme.0000398422.59986.78 · Cited by 4
Applying a neural circuit taxonomy in depression and anxiety for personalized psychiatry
Williams, L. M., & Goldstein‐Piekarski, A. N. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813176-3.00042-0 · Cited by 4
Wojciechowski, T. W., & Krupa, J. M. (2024) · International Journal of Offender Therapy and Comparative Criminology · doi:10.1177/0306624x241236717 · Cited by 5
Rudolph, K. D., Troop‐Gordon, W., Modi, H. H., & Granger, D. A. (2018) · Developmental Psychobiology · doi:10.1002/dev.21600 · Cited by 4
Neurogenetics Approaches to Mapping Pathways in Developmental Psychopathology
Hyde, L. W., Swartz, J. R., Waller, R. E., & Hariri, A. R. (2016) · Wiley eBooks · doi:10.1002/9781119125556.devpsy212 · Cited by 4
Behavioral and Neurostructural changes associated with Chronic Amygdala HyperactivationPreprint
Misquitta, K. A., Codeluppi-Arrowsmith, S. A., Knoch, J., Bansal, Y., Tomoda, T., Ellegood, J., Lerch, J. P., Sibille, E. L., Nikolova, Y. S., & Banasr, M. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.09.11.459894 · Cited by 4
Vu, B.-P., Nguyen, H.-G., & Dang, H. (2025) · Journal of Child and Adolescent Mental Health · doi:10.2989/17280583.2025.2490649 · Cited by 4
Nejati, V., Khorrami, A. S., Vaziri, Z., Shahri, F., Yazdchi, M., Abdolmanafi, V., Paydarfard, S., & Golshan, A. (2024) · Journal of Neural Transmission · doi:10.1007/s00702-024-02852-5 · Cited by 3
Identification of structural brain alterations in adolescents with depressive symptomatology
Bashford‐Largo, J., Blair, J., Blair, K. S., Dobbertin, M. D., Dominguez, A. J., Hatch, M., & Bajaj, S. (2023) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2023.110723 · Cited by 3
Brain Changes After a Parenting Intervention in Adolescent Girls With Internalizing Symptoms
Lin, S. C., Kehoe, C. E., Zhao, J., Havighurst, S. S., Schwartz, O., Yap, M. B. H., Pozzi, E., & Whittle, S. (2025) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2025.3845 · Cited by 3
Imaging the Amygdala: Changing the Face of Gene Discovery in Child Psychiatry
Arnold, P. D., Hanna, G. L., & Rosenberg, D. R. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2009.10.005 · Cited by 3
Ekbäck, E., Rådmark, L., Granåsen, G., Svärling, R., Sörlin, M., Schönbeck, C., & Henje, E. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1130035 · Cited by 2
Working Memory, Rumination, and Autobiographical Memory Specificity Impairment
Rahgosha, P., Hadinezhad, P., Hosseini, S. H., & Abedini, E. (2023) · Iranian Rehabilitation Journal · doi:10.32598/irj.21.3.1862.1 · Cited by 2
Carranza, A. F., Yoon, L., Rohrsetzer, F., Battel, L., Manfro, P. H., Rohde, L. A., Viduani, A. C., Zajkowska, Z., Mondelli, V., Kieling, C., et al. (2024) · International Journal of Adolescence and Youth · doi:10.1080/02673843.2024.2354910 · Cited by 2
Turpyn, C. C., Niehaus, C. E., Gonçalves, S. F., & Jenness, J. L. (2020) · Journal of Pediatric Neuropsychology · doi:10.1007/s40817-020-00080-9 · Cited by 2
Cadaveira, F. (2012) · Trastornos Adictivos · Cited by 2
Kemala, C. N., Jongsma, M. L. A., Hendrawan, D., & Becker, E. S. (2023) · Psychological Research on Urban Society · doi:10.7454/proust.v6i1.1105 · Cited by 2
黄, 明. (2025) · Advances in Clinical Medicine · doi:10.12677/acm.2025.152456 · Cited by 1
Depression im Kindes- und Jugendalter – Theorie und Empirie
Abel, U., & Hautzinger, M. (2013) · Springer eBooks · doi:10.1007/978-3-642-29791-5_1 · Cited by 1
Treatment Strategies for Depression in Youth
Tompson, M. C., & Boger, K. D. (2008) · Springer eBooks · doi:10.1007/978-0-387-09530-1_8 · Cited by 1
Pagliaccio, D. (2015) · Open Scholarship Institutional Repository (Washington University in St. Louis) · doi:10.7936/k7t151t3 · Cited by 1
Treatment Strategies for Depression in Youth
Kemp, G. N., O’Connor, E., Kritikos, T. K., Curren, L. C., & Tompson, M. C. (2017) · Autism and child psychopathology series · doi:10.1007/978-3-319-71210-9_10 · Cited by 1
Touchscreen Assessment of Motivation and Reinforcement-Related Choice Behaviour in Mice
Phillips, B. U. (2017) · Apollo (University of Cambridge) · doi:10.17863/cam.24393 · Cited by 1
Yang, G. (2013) · eScholarship (California Digital Library)
Riem, M. M. E., Bakermans‐Kranenburg, M. J., van IJzendoorn, M. H., Out, D., & Rombouts, S. A. R. B. (2016) · Dziecko Krzywdzone. Teoria, badania, praktyka
Waye, S. (2019) · Memorial University Research Repository (Memorial University)
Nikolova, Y. S. (2014) · DukeSpace (Duke University)
Drake, T. C. (2021) · Queensland University of Technology · doi:10.5204/thesis.eprints.214321
Kaska, S., & Mazei‐Robison, M. S. (2016) · Wiley eBooks · doi:10.1002/9780470015902.a0025796
The complex association of VRK2 with major depressive disorder in Han Chinese population
Luo, B., Huo, J., Zhao, L., Guo, X., Zhang, L., Yang, Y., Li, S., Zhong, J., Lv, L., Li, M., et al. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.04.129
Jassim, N., Hagan, C. C., Holt, R., Goodyer, I. M., & Suckling, J. (2025) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2025.112019
Vu, B.-P., Nguyen, H.-G., & Dang, H.-M. (2024) · Research Square · doi:10.21203/rs.3.rs-4524866/v1
Zhao, L., Long, Y., Zeng, K., Chen, S., Qiu, T., & Fu, O. (2026) · Journal of Integrative Neuroscience · doi:10.31083/jin48170
Li, H., Wen, Y., Cheng, W., Zhuang, L., & 刘志芬 (2026) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.70421
Metadata
- Authors
- Yang, T. T., Simmons, A. N., Matthews, S. C., Tapert, S. F., Frank, G. K., Max, J. E., Bischoff-Grethe, A., Lansing, A. E., Brown, G., Strigo, I. A., Wu, J., & Paulus, M. P.
- Affiliations
- University of California San Diego (US)
- University of Colorado Denver (US)
- Corresponding author
- Yang, Tony T.
- ORCID
- Venue
- Journal of the American Academy of Child & Adolescent Psychiatry
- Publisher
- Elsevier BV
- Published
- 2010-01
- Volume
- 49
- Issue
- 1
- Pages
- 42-51
- ISSN
- 0890-8567 (ISSN-L)
- PMC
- PMC2935523
- OpenAlex
- W2163349072
- Cited by
- 176
- References
- 47
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 13 · 2023: 15 · 2022: 8 · 2021: 9 · 2020: 12 · 2019: 15 · 2018: 7 · 2017: 12 · 2016: 13 · 2015: 14 · 2014: 11 · 2013: 15 · 2012: 12
- FWCI
- 7.37
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Alliance for Research on Schizophrenia and Depression
- National Institute of Mental Health (K23MH70791, K23MH070791, K23MH080135)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Keywords
- adolescent depression, major depressive disorder, amygdala activation, amygdala hyperactivity, facial emotion recognition, emotional processing
- MeSH terms
- Adolescent, Amygdala, Brain Mapping, Major Depressive Disorder, Depressive Disorder, Major, Dominance, Cerebral, Emotions, Female, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Pattern Recognition, Visual, Reference Values
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review