Epigenetic intergenerational transmission: mothers’ adverse childhood experiences and DNA methylation

Sex-Specific Placental Responses in Fetal Development

Rosenfeld, C. S. (2015) · Endocrinology · doi:10.1210/en.2015-1227 · Cited by 473 · see citing works

Sensitive periods for the effect of childhood adversity on DNA methylation: results from a prospective, longitudinal study

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Data Resource Profile: Accessible Resource for Integrated Epigenomic Studies (ARIES)

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Childhood Maltreatment and Perinatal Mood and Anxiety Disorders: A Systematic Review

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Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

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Maternal prenatal stress and infant DNA methylation: A systematic review

Sosnowski, D. W., Booth, C., York, T. P., Amstadter, A. B., & Kliewer, W. (2018) · Developmental Psychobiology · doi:10.1002/dev.21604 · Cited by 111 · see citing works

DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons

Jovanova, O., Nedeljkovic, I., Spieler, D., Walker, R. M., Liu, C., Luciano, M., Bressler, J., Brody, J. A., Drake, A. J., Evans, K. L., et al. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.1725 · Cited by 108 · see citing works

DNA methylation at stress‐related genes is associated with exposure to early life institutionalization

Non, A. L., Hollister, B. M., Humphreys, K. L., Childebayeva, A., Esteves, K. C., Zeanah, C. H., Fox, N. A., Nelson, C. A., & Drury, S. S. (2016) · American Journal of Physical Anthropology · doi:10.1002/ajpa.23010 · Cited by 107 · see citing works

Glucocorticoid receptor DNA methylation, childhood maltreatment and major depression

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Differential DNA methylation in peripheral blood mononuclear cells in adolescents exposed to significant early but not later childhood adversity

Esposito, E. A., Jones, M. J., Doom, J. R., MacIsaac, J. L., Gunnar, M. R., & Kobor, M. S. (2016) · Development and Psychopathology · doi:10.1017/s0954579416000055 · Cited by 71 · see citing works

Childhood Abuse, Promoter Methylation of Leukocyte NR3C1 and the Potential Modifying Effect of Emotional Support

Shields, A. E., Wise, L. A., Ruiz-Narváez, E., Seddighzadeh, B., Byun, H., Cozier, Y. C., Rosenberg, L. A., Palmer, J. R., & Baccarelli, A. (2016) · Epigenomics · doi:10.2217/epi-2016-0074 · Cited by 56 · see citing works

Epigenetics and Early Life Adversity: Current Evidence and Considerations for Epigenetic Studies in the Context of Child Maltreatment

Bouvette–Turcot, A., Meaney, M. J., & O’Donnell, K. J. (2018) · Child maltreatment solutions network · doi:10.1007/978-3-319-72589-5_7 · Cited by 4 · see citing works

Prioritizing Maternal Mental Health in Addressing Morbidity and Mortality

Wisner, K. L., Murphy, C., & Thomas, M. M. (2024) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2023.5648 · Cited by 91 · see citing works

Biological Embedding of Early-Life Adversity and a Scoping Review of the Evidence for Intergenerational Epigenetic Transmission of Stress and Trauma in Humans

Zhou, A., & Ryan, J. (2023) · Genes · doi:10.3390/genes14081639 · Cited by 57 · see citing works

Miswiring the brain: Human prenatal Δ9-tetrahydrocannabinol use associated with altered fetal hippocampal brain network connectivity

Thomason, M. E., Palopoli, A. C., Jariwala, N. N., Werchan, D. M., Chen, A., Adhikari, S., Espinoza‐Heredia, C., Brito, N. H., & Trentacosta, C. J. (2021) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2021.101000 · Cited by 42 · see citing works

Intergenerational associations of adverse and positive maternal childhood experiences with young children’s psychosocial well-being

Zhu, Y., Zhang, G., & Anme, T. (2023) · European Journal of Psychotraumatology · doi:10.1080/20008066.2023.2185414 · Cited by 33 · see citing works

The relationship between parental adverse childhood experiences and the health, well-being and development outcomes of their children: a systematic review

Arnold, R., Ahmed, F., Clarke, A., Quinn, N., Beenstock, J., & Holland, P. (2023) · Public Health · doi:10.1016/j.puhe.2023.03.025 · Cited by 30 · see citing works

Pregnant women with bipolar disorder who have a history of childhood maltreatment: Intergenerational effects of trauma on fetal neurodevelopment and birth outcomes

Babineau, V., McCormack, C. A., Feng, T., Lee, S., Berry, O. O., Knight, B. T., Newport, D. J., Stowe, Z. N., & Monk, C. E. (2022) · Bipolar Disorders · doi:10.1111/bdi.13207 · Cited by 26 · see citing works

The transition to parenthood in obstetrics: enhancing prenatal care for 2-generation impact

Monk, C., Dimidjian, S., Galinsky, E., Gregory, K. D., Hoffman, M. C., Howell, E. A., Miller, E. S., Osborne, C., Rogers, C. E., Saxbe, D. E., et al. (2022) · American Journal of Obstetrics & Gynecology MFM · doi:10.1016/j.ajogmf.2022.100678 · Cited by 19 · see citing works

Maternal adverse childhood experiences (ACEs) and DNA methylation of newborns in cord blood

Collender, P. A., Bozack, A. K., Veazie, S., Nwanaji‐Enwerem, J. C., van der Laan, L. W. P., Kogut, K. R., Riddell, C. A., Eskenazi, B., Holland, N., Deardorff, J., et al. (2023) · Clinical Epigenetics · doi:10.1186/s13148-023-01581-y · Cited by 19 · see citing works

Association of adverse childhood experiences with irritable bowel syndrome in Mexican adults: A cross‐sectional study

Priego-Parra, B. A., Triana‐Romero, A., Lajud-Barquín, F. A., Higuera‐DelaTijera, M. D. F., Vázquez, S., Salgado‐Álvarez, G. A., Mora, U. G., Cruz‐Márquez, M. Á., Cano-Contreras, A. D., Cid, H. V., et al. (2024) · Neurogastroenterology & Motility · doi:10.1111/nmo.14743 · Cited by 19 · see citing works

Exploring sex differences in fetal programming for childhood emotional disorders

Galbally, M., Watson, S., Lappas, M., de Kloet, E. R., Wyrwoll, C. S., Mark, P. J., & Lewis, A. J. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2022.105764 · Cited by 19 · see citing works

The Impact of Maternal Interpersonal Violent Trauma and Related Psychopathology on Child Outcomes and Intergenerational Transmission

Graf, S., & Schechter, D. S. (2024) · Current Psychiatry Reports · doi:10.1007/s11920-024-01491-7 · Cited by 14 · see citing works

Causes of health inequities

Lee, A., & Padilla, C. (2022) · Current Opinion in Anaesthesiology · doi:10.1097/aco.0000000000001142 · Cited by 11 · see citing works

Reconsidering the nature of threat in infancy: Integrating animal and human studies on neurobiological effects of infant stress

Lyons‐Ruth, K., Chasson, M., Khoury, J. E., & Ahtam, B. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105746 · Cited by 11 · see citing works

Maternal adverse childhood experiences (ACEs) and offspring imprinted gene DMR methylation at birth

Vidal, A. C., Sosnowski, D. W., Marchesoni, J., Grenier, C., Thorp, J. M., Murphy, S. K., Johnson, S. B., Schlief, B., & Hoyo, C. (2023) · Epigenetics · doi:10.1080/15592294.2023.2293412 · Cited by 8 · see citing works

An Examination of the Impact of Psychosocial Factors on Mother-to-Child Trauma Transmission in Post-Migration Contexts Using Interpretative Phenomenological Analysis

Ngameni, É. G., Moro, M. R., Kokou‐Kpolou, C. K., Radjack, R., Dozio, E., & Husseini, M. E. (2022) · Child Care in Practice · doi:10.1080/13575279.2022.2071220 · Cited by 7 · see citing works

Pathways explaining the intergenerational effects of ACEs: The mediating roles of mothers' mental health and the quality of their relationships with their children

Swords, L., Kennedy, M., & Spratt, T. (2024) · Journal of Applied Developmental Psychology · doi:10.1016/j.appdev.2024.101644 · Cited by 6 · see citing works

A Cross-Generational Methylomic Signature of Infant Maltreatment in Newborn Rhesus Macaques

Lardenoije, R., Smulders, M. N. C. A., Morin, E. L., Howell, B., Guzman, D., Meyer, J. S., Ressler, K. J., Sánchez, M., & Klengel, T. (2025) · Biological Psychiatry · doi:10.1016/j.biopsych.2025.02.901 · Cited by 6 · see citing works

Maternal caregiving moderates relations between maternal childhood maltreatment and infant cortisol regulation

Chasson, M., Khoury, J. E., Enlow, M. B., & Lyons‐Ruth, K. (2025) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.14171 · Cited by 6 · see citing works

Adverse Childhood Experiences (ACEs) in 252 Board-Certified Plastic Surgeons: Prevalences, ACE Clustering, and Effects on Adult Health and Behaviors, Including Self-Defined Depression, Work Addiction, and Burnout

Constantian, M. B., & Zaborek, N. A. (2024) · Aesthetic Surgery Journal · doi:10.1093/asj/sjae214 · Cited by 2 · see citing works

MicroRNAs in Umbilical Cord Blood and Development in Full-Term Newborns: A Prospective Study

Wang, L., Tsai, C., Chao, H., Lee, S.-Y., Chen, C., & Li, S. (2024) · Biomarker Insights · doi:10.1177/11772719241258017 · Cited by 2 · see citing works

Literature Review 2020

Young, G. C. (2021) · Springer eBooks · doi:10.1007/978-3-030-82540-9_8

Study Registration: Encouraging the Practice of Hypothetical-Deductive Research in the Journal Revisited

Novins, D. K., Althoff, R. R., & Billingsley, M. K. (2023) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2023.09.532

Adversité et cardiologie : la violence infantile, une bombe à retardement

Houppe, J.-P. (2025) · Archives des Maladies du Coeur et des Vaisseaux - Pratique · doi:10.1016/j.amcp.2025.02.015

Building Back Better?

Schrecker, T., & Bambra, C. L. (2025) · Palgrave Macmillan UK eBooks · doi:10.1057/978-1-349-96127-6_9

High Maternal Adverse Childhood Experience Exposure is Associated with Reduced Offspring Growth in the First Six Months of Life: Findings from a Prospective StudyPreprint

Ketelaars, M., Bos, A. J. M., de Grauw, A. M., Phaff, S. J., Reijnierse, J. J., van den Akker, C. H. P., Jong, J. C. K., & van Veen, M. (2026) · Research Square · doi:10.21203/rs.3.rs-9646735/v1

Stage 2 Registered Report: Epigenetic Intergenerational Transmission: Mothers’ Adverse Childhood Experiences and DNA Methylation

Scorza, P., Duarte, C. S., Lee, S., Wu, H., Posner, J., Baccarelli, A., & Monk, C. (2023) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2023.02.018 · Cited by 18 · see citing works

Epigenetics and Early Life Adversity: Current Evidence and Considerations for Epigenetic Studies in the Context of Child Maltreatment

Bouvette–Turcot, A., Meaney, M. J., & O’Donnell, K. J. (2018) · Child maltreatment solutions network · doi:10.1007/978-3-319-72589-5_7 · Cited by 4 · see citing works

P424. Epigenetic Intergenerational Transmission: Mothers’ Adverse Childhood Experiences and DNA Methylation

Scorza, P., Duarte, C. S., Lee, S., Wu, H., Posner, J., Baccarelli, A., & Monk, C. E. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2022.02.660 · Cited by 2 · see citing works

Epigenetic brain modifications associated with early-life adversity

Roth, T. L., & Blaze, J. (2012) · European Journal of Psychotraumatology · doi:10.3402/ejpt.v3i0.19490

New insights into the link between childhood adversity and epigenetic changes

Lin, P., & Eapen, V. (2023) · The Lancet Child & Adolescent Health · doi:10.1016/s2352-4642(23)00106-2