Wound healing and treating wounds
Abstract
Wounds are an excellent example of how the field of dermatology represents a cross-section of many medical disciplines. For instance, wounds may be caused by trauma, vascular insufficiency, and underlying medical conditions, such as diabetes, hypertension, and rheumatologic and inflammatory disease. This continuing medical education article provides an overview of wound healing and the pathophysiology of chronic wounds and reviews the broad differential diagnosis of chronic wounds. It also describes the initial steps necessary in evaluating a chronic wound and determining its underlying etiology.
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Normal wound healing can generally be broken down into four overlapping but distinct steps: hemostasis, inflammation, proliferation and repair, and wound remodeling.
“normal wound healing can generally be broken down into four over-lapping but distinct steps (Fig. 1). These steps include hemostasis (minutes to hours after injury), inflammation (days 1–3), proliferation and repair (days 4–21), and lastly, wound remodeling (days 21–365) [8, 9].”
From Immunology of Wound Healing (2018) · cites this paper as [8]
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Ellis, S., Lin, E. J., & Tartar, D. (2018) · Current Dermatology Reports · doi:10.1007/s13671-018-0234-9 · Cited by 625 · see citing works
Chronic wounds: Current status, available strategies and emerging therapeutic solutions
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Patch repair of deep wounds by mobilized fascia
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Wang, Y., Cao, Z., Wei, Q., Ma, K., Hu, W., Huang, Q., Su, J., Li, H., Zhang, C., & Fu, X. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.05.018 · Cited by 225 · see citing works
- Authors
- Morton, L. M., & Phillips, T. J.
- Affiliations
- Boston University (US)
- Corresponding author
- Morton, Laurel M.
- ORCID
- Phillips, Tania J.
- Venue
- Journal of the American Academy of Dermatology
- Publisher
- Elsevier BV
- Published
- 2016-04
- Volume
- 74
- Issue
- 4
- Pages
- 589-605
- ISSN
- 0190-9622 (ISSN-L)
- OpenAlex
- W2298890574
- Cited by
- 475
- References
- 244
- Citations by year
- 2026: 48 · 2025: 63 · 2024: 82 · 2023: 65 · 2022: 66 · 2021: 45 · 2020: 34 · 2019: 36 · 2018: 20 · 2017: 14 · 2016: 1
- FWCI
- 25.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Academy of Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetic Foot Ulcer Assessment and Management
- Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
- Keywords
- wound healing, chronic wounds, wound assessment, diabetes mellitus, vascular insufficiency, trauma (physical injury), inflammatory diseases
- MeSH terms
- Acute Disease, Chronic Disease, Pressure Ulcer, Diagnosis, Differential, Education, Medical, Continuing, Female, Humans, Male, Prognosis, Wound Healing, Wounds and Injuries, Skin Diseases, Vascular, Diabetic Foot, Plastic Surgery Procedures, Dermatologic Surgical Procedures
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