Cited by 426Complementary and Alternative Medicine StudiesPhytochemistry Medicinal Plant ApplicationsNephrotoxicity and Medicinal Plants

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Use of Herbal Products and Potential Interactions in Patients With Cardiovascular Diseases

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Tachjian, Ara, Maria, Viqar, Jahangir, Arshad·2010·Journal of the American College of Cardiology

DOI 10.1016/j.jacc.2009.07.074PMC PMC2831618

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Abstract

More than 15 million people in the U.S. consume herbal remedies or high-dose vitamins. The number of visits to providers of complementary and alternative medicine exceeds those to primary care physicians, for annual out-of-pocket costs of $30 billion. Use of herbal products forms the bulk of treatments, particularly by elderly people who also consume multiple prescription medications for comorbid conditions, which increases the risk of adverse herb-drug-disease interactions. Despite the paucity of scientific evidence supporting the safety or efficacy of herbal products, their widespread promotion in the popular media and the unsubstantiated health care claims about their efficacy drive consumer demand. In this review, we highlight commonly used herbs and their interactions with cardiovascular drugs. We also discuss health-related issues of herbal products and suggest ways to improve their safety to better protect the public from untoward effects.

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Authors: Tachjian, A., Maria, V., & Jahangir, A.
Affiliations: Mayo Clinic (US)
Corresponding author: Jahangir, Arshad
ORCID: Jahangir, Arshad
Venue: Journal of the American College of Cardiology
Publisher: Elsevier BV
Published: 2010-02
Volume: 55
Issue: 6
Pages: 515-525
ISSN: 0735-1097 (ISSN-L)
DOI: 10.1016/j.jacc.2009.07.074
PMC: PMC2831618
OpenAlex: W2151268696
Cited by: 426
References: 88
Citations by year: 2026: 7 · 2025: 12 · 2024: 26 · 2023: 19 · 2022: 35 · 2021: 23 · 2020: 38 · 2019: 25 · 2018: 30 · 2017: 28 · 2016: 34 · 2015: 39 · 2014: 23 · 2013: 30 · 2012: 25
FWCI: 6.14
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 1261 d)
Locations: Journal of the American College of Cardiology (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute on Aging (R01AG021201, AG-21201)
National Heart, Lung, and Blood Institute (R01HL089542, HL089542)
Topics: Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry Medicinal Plant Applications
Health Sciences › Medicine › Nephrology › Nephrotoxicity and Medicinal Plants
Keywords: herbal products, complementary and alternative medicine, herb-drug interactions, cardiovascular disease, cardiovascular drugs, elderly patients, polypharmacy, herbal medicine safety
MeSH terms: Cardiovascular Agents, Cardiovascular Diseases, Humans, Phytotherapy, Plants, Medicinal, Treatment Outcome, Herb-Drug Interactions

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Use of Herbal Products and Potential Interactions in Patients With Cardiovascular Diseases

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