Cited by 1,028Aortic Disease and Treatment ApproachesCardiac Valve Diseases and TreatmentsCongenital Heart Disease Studies

The DOI matches its Crossref record; 140 of the 143 references it cites were found in a registry or an index.

Bicuspid Aortic Valve Disease

Open access

Siu, Samuel C., Silversides, Candice K.·2010·Journal of the American College of Cardiology

DOI 10.1016/j.jacc.2009.12.068

Open this paper in CoChat — free account Open PDF

Abstract

Bicuspid aortic valve (BAV) disease is the most common congenital cardiac defect. While the BAV can be found in isolation, it is often associated with other congenital cardiac lesions. The most frequent associated finding is dilation of the proximal ascending aorta secondary to abnormalities of the aortic media. Changes in the aortic media are present independent of whether the valve is functionally normal, stenotic, or incompetent. Although symptoms often manifest in adulthood, there is a wide spectrum of presentations ranging from severe disease detected in utero to asymptomatic disease in old age. Complications can include aortic valve stenosis or incompetence, endocarditis, aortic aneurysm formation, and aortic dissection. Despite the potential complications, 2 large contemporary series have demonstrated that life expectancy in adults with BAV disease is not shortened when compared with the general population. Because BAV is a disease of both the valve and the aorta, surgical decision making is more complicated, and many undergoing aortic valve replacement will also need aortic root surgery. With or without surgery, patients with BAV require continued surveillance. Recent studies have improved our understanding of the genetics, the pathobiology, and the clinical course of the disease, but questions are still unanswered. In the future, medical treatment strategies and timing of interventions will likely be refined. This review summarizes our current understanding of the pathology, genetics, and clinical aspects of BAV disease with a focus on BAV disease in adulthood.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.jacc.2009.12.068

Cites

140 of 140 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.176857 · Cited by 8,487
2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.05.007 · Cited by 2,245
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease: Executive Summary
Warnes, C. A., Williams, R. G., Bashore, T. M., CHILD, J. S., Connolly, H. M., Dearani, J. A., del Nido, P. J., Fasules, J. W., Graham, T. P., Hijazi, Z. M., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.190811 · Cited by 2,068
Clinical Factors Associated With Calcific Aortic Valve Disease
Stewart, B. F., Siscovick, D., Lind, B. K., Gardin, J. M., Gottdiener, J. S., Smith, V. E., Kitzman, D. W., & Otto, C. M. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(96)00563-3 · Cited by 2,029
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.05.021 · Cited by 1,702
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease
Warnes, C. A., Williams, R. G., Bashore, T. M., CHILD, J. S., Connolly, H. M., Dearani, J. A., del Nido, P. J., Fasules, J. W., Graham, T. P., Hijazi, Z. M., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.10.001 · Cited by 1,553
Mutations in NOTCH1 cause aortic valve disease
Garg, V., Muth, A. N., Ransom, J. F., Schluterman, M. K., Barnes, R., King, I. N., Grossfeld, P. D., & Srivastava, D. (2005) · Nature · doi:10.1038/nature03940 · Cited by 1,509
Suggested standards for reporting on arterial aneurysms
Johnston, K. W., Rutherford, R. B., Tilson, M. D., Shah, D. M., Hollier, L. H., & Stanley, J. C. (1991) · Journal of Vascular Surgery · doi:10.1067/mva.1991.26737 · Cited by 1,369
Predictors of Outcome in Severe, Asymptomatic Aortic Stenosis
Rosenhek, R., Binder, T. M., Porenta, G., Lang, I. M., Christ, G., SCHEMPER, M., Maurer, G., & Baumgartner, H. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008313430903 · Cited by 1,332
A classification system for the bicuspid aortic valve from 304 surgical specimens
Sievers, H.-H., & Schmidtke, C. (2007) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2007.01.039 · Cited by 1,222

Show all 143 references

Research works printed but not linked: 4

Osler, 1886, The bicuspid condition of the aortic valve, Trans Assoc Am Physicians, 2, 185
Nadas, 1977, Report from the Joint Study on the Natural History of Congenital Heart Defects, Circulation, 56, I36
Bonow, 2006, J Am Coll Cardiol, 48, e1, 10.1016/j.jacc.2006.05.021 · DOI
Warnes, 2008, J Am Coll Cardiol, 52, e1, 10.1016/j.jacc.2008.10.002 · DOI

Sorted by citations

Items 901–999 of 999

Aortic Stenosis
Booher, A. M., Shea, M. J., & Deeb, G. M. (2020) · Springer eBooks · doi:10.1007/978-3-030-28328-5_22
The Impact of a Bicuspid Aortic Valve on Aortic Geometry and Function in Patients with Aortic Coarctation: A Comprehensive CMR Study
Schweikert, L., Gabbert, D. D., Krupičková, S., & Voges, I. (2021) · Congenital Heart Disease · doi:10.32604/chd.2021.016635
Valvular heart disease
Vaideeswar, P., Singaravel, S., & BUTANY, J. W. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822224-9.00008-6
Surgical outcomes among children with bicuspid aortic valve: 17 years of experience in a single center. First report in Mexico
Ortega‐Zhindón, D. B., Calderón-Colmenero, J. E., Pereira‐López, G. I., Sandoval, J. P., Rivera‐Buendía, F., & Cervantes-Salazar, J. L. (2022) · Journal of Cardiac Surgery · doi:10.1111/jocs.17024
Maternal and fetal outcomes of bicuspid aortic valve with early-onset complications
Truly, T., Huang, M., & Prakash, S. K. (2022) · Cardiology in the Young · doi:10.1017/s1047951122003468
Bicuspid Aortic Valve
Khan, K. S., & Ullah, I. (2023) · Springer eBooks · doi:10.1007/978-3-031-23062-2_16
TAVR for Bicuspid Aortic Valve
Adrichem, R., & Mieghem, N. M. V. (2023) · doi:10.1002/9781119807841.ch10
Short-Term Efficacy of Transcatheter Aortic Valve Replacement in Patients with Severe Bicuspid Aortic Stenosis
王, 立. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2022.132172
Neoaortic Bicuspid Valve Replacement in Patient After Arterial Switch Operation to Correct Dextro-Transposition of the Great Arteries
Сергеевич, С. В., Вадимович, Р. А., Владимирович, Р. Н., Kornoukhov, O. Y., Niyazov, S. S., Марсовна, Б. Н., & Muslimov, R. S. (2023) · Russian Sklifosovsky Journal Emergency Medical Care · doi:10.23934/2223-9022-2022-11-4-718-724
Aortic valve surgery in the pediatric population: pathophysiology, clinical features and management
PANDA, A., GOYAL, K., Mishra, V. K., Khan, I. H., Panesa, A., Akhteruzzaman, T., & Harky, A. (2023) · Minerva Pediatrics · doi:10.23736/s2724-5276.23.07012-x
Transcatheter Aortic Valve Implantation
de Chazal, H. A. M., Zgheib, A., Ismaili, A. A., Abualsaud, A. O., Spaziano, M., Martucci, G. J., & Piazza, N. (2023) · Springer eBooks · doi:10.1007/978-3-031-25541-0_11
Sport bei linksventrikulären Klappenvitien
Kindermann, W., Niederdöckl, J. D., Urhausen, A. J. P., & Scharhag, J. (2023) · Springer eBooks · doi:10.1007/978-3-662-65165-0_24
Late Diagnosic of Bicuspid Aortic Valve with Severe Aortic Stenosis and Large Thoracic Aortic Aneurysm: Case Report and Review of the Literature.
Harrak, M. E., Tabti, F., Ameur, A., Rhemimet, C., Kihoul, O., Dib, H., & Zarzur, P. (2023) · Research and Analysis Journal · doi:10.18535/raj.v6i6.412
Long Term Follow Up of Adults with Congenital Heart Disease
Haeffele, C. L., Bykhovsky, M. R., Vaikunth, S. S., & Lui, G. K. (2023) · Springer eBooks · doi:10.1007/978-3-030-42937-9_97-1
Navigating the challenges of bicuspid aortic valve-aortopathy
Kanagala, S. G., Sawhney, A., Parikh, K., Gupta, V., Mahmood, T., Anamika, F., Jain, R., & Garg, N. (2023) · Global Cardiology Science and Practice · doi:10.21542/gcsp.2023.27
Prognostic value of mitral valve prolapse and mild mitral regurgitation in competitive athletes
Grigorova, B., & Chobanov, A. (2023) · Bulgarian Cardiology · doi:10.3897/bgcardio.29.e107881
Abnormalities of Left Ventricular Inflow and Outflow
Geva, T., & Banka, P. (2023) · Springer eBooks · doi:10.1007/978-3-031-29235-4_11
Surgery for Bicuspid Aortopathy
Svensson, L. G., & Desai, M. Y. (2023) · JACC Advances · doi:10.1016/j.jacadv.2023.100627
Development of a methodological framework to probe regional mechanics of the aneurysmal ascending thoracic aorta
Tarraf, S. A. (2023) · doi:10.17760/d20592707
Kalp Kapak Hastalıkları ve Spor Kardiyolojisi
Özyıldırım, S. (2023) · doi:10.5152/0105
Ritim Bozuklukları ve Spor Kardiyolojisi
Aslan, Ş., & Yıldız, M. (2023) · doi:10.5152/0109
Perikardit ve Spor Kardiyolojisi
Coşkun, O. (2023) · doi:10.5152/0107
Fonksiyonel Tıp ve Spor İlişkisi
Yıldız, M. (2023) · doi:10.5152/0113
Sporcu Kalbi
Altan, M. (2023) · doi:10.5152/0102
Kronik Koroner Sendromlar ve Spor Kardiyolojisi
Si̇nan, Ü. Y. (2023) · doi:10.5152/0104
Erişkin Doğumsal Kalp Hastalıkları ve Spor Kardiyolojisi
Gürsoy, M. O., & Yıldız, M. (2023) · doi:10.5152/0110
Miyokardit ve Spor Kardiyolojisi
Dinçer, Ş. (2023) · doi:10.5152/0108
Kardiyomiyopatiler ve Spor Kardiyolojisi
Barman, H. A. (2023) · doi:10.5152/0106
Aortopati ve Spor Kardiyolojisi
Kahraman, S., & Yıldız, M. (2023) · doi:10.5152/0111
Kardiyovasküler Sistem ve Egzersiz
Sönmez, O. F. (2023) · doi:10.5152/0101
Spor Kardiyolojisi ve Kalp Damar Hastalıkları
Barman, H. A., Alttan, M., Gürsoy, M. O., Yıldız, M., Coşkun, O., Sönmez, O. F., Demi̇r, R., Özyıldırım, S., Kahraman, S., Dinçer, Ş., et al. (2023) · doi:10.5152/0100 · Cited by 4
Sporcularda Ani Kalp Ölümü
Yıldız, M. (2023) · doi:10.5152/0112
Kronik Kalp Yetersizliği ve Spor Kardiyolojisi
(2023) · doi:10.5152/0103
A Novel Design and Simulation of a Nano Prosthetic Artificial Heart Valves
Ali, S. M. (2023) · International Journal of Engineering · doi:10.5829/ije.2024.37.02b.03
ACHD
Green, A., & Alegría, J. R. (2023) · Springer eBooks · doi:10.1007/978-3-031-35819-7_29
The Frequency of Bicuspid Aortic Valve in Healthy Young Adults Who Applied to the Health Board: A Tertiary Centre Experience: Retrospective Study
Oflar, E., Karabulut, D., Ertuğrul, A. S., Yıldız, C., Aktürk, İ. F., Çağlar, F. N. T., & ŞAHİN, A. (2023) · Turkiye Klinikleri Cardiovascular Sciences · doi:10.5336/cardiosci.2022-93768
A case of pregnant patient with stenotic bicuspid aortic valve
Lewek, J., Maciejewski, M., Banach, M., & Bielecka-Dabrowa, A. M. (2023) · Clinical Case Reports · doi:10.1002/ccr3.8104
Epidemiological Profile of Cyanotic Congenital Heart Disease in the “B” Surgery Department of Point G University Hospital, before the Advent of Extracorporeal Circulation
Kanté, A., Konaté, D., Keita, M. A., Diakité, M. L., Keïta, B., Bengaly, B., Togola, B., Traoré, D., Ongoïba, N., & Yéna, S. (2023) · World Journal of Cardiovascular Surgery · doi:10.4236/wjcs.2023.1311017
The Impact of SARS-Cov-2 Infection on the Cardiovascular System
Neculăesei, S., Anghel, R., Costache, A. D., & Mitu, F. (2023) · Internal Medicine · doi:10.2478/inmed-2023-0267
Aortic Regurgitation
Khalil, O. A., & Khalil, A. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-18798-8.00001-0
Editorial: The puzzle of TAVR in bicuspid aortic valves: One piece at a time
Lahoud, R. N., & Krishnan, A. M. (2024) · Cardiovascular revascularization medicine · doi:10.1016/j.carrev.2024.02.011
Transcarotid TAVR for Severe Bicuspid Aortic Stenosis With Virtually Atretic Coarctation of the Thoracic Aorta
Tungate, R. M., Chane, M., Sun, J. C. J., Tiwari, A. K., Urgun, D. A., Patel, P. M., & Frangieh, A. H. (2024) · Journal of the Society for Cardiovascular Angiography & Interventions · doi:10.1016/j.jscai.2024.101940
Occlusion Devices for Cardiovascular Disease
Zeng, Y., Zhang, Y., & Tu, C. (2024) · Springer eBooks · doi:10.1007/978-981-19-7712-1_8
TAVR with self- expandable valves: what challenges in bicuspid aortic valve disease?
JOURANI, S., Yahya, A. A., ELJAMILI, M., Elkarimi, S., & Elhattaoui, M. (2024) · World Journal of Advanced Research and Reviews · doi:10.30574/wjarr.2024.22.2.1385
MÉTODOS CONTEMPORÂNEOS DE GESTÃO DOS ANEURISMAS DA AORTA TORÁCICA: PATOLOGIA, DIAGNÓSTICO E OPÇÕES DE TRATAMENTO
Senne, C. A., Polatto, G. R., Huck, L., Peres, M. D. P., de Moraes, R. M. D., de Paula, R. C., de Souza, R. N. S. N., Cherbo, T., & Filho, D. D. C. M. (2024) · EPITAYA eBooks · doi:10.47879/ed.ep.2024479p419
Transcatheter aortic valve implantation in patients with bicuspid aortic valve
Mkrtychev, D. S., Komlev, A. E., Колегаев, А. С., Lepilin, P. M., Кучин, И. В., Саличкин, Д. В., Kabardieva, M. R., & Эмвярович, И. Т. (2024) · Russian Journal of Cardiology and Cardiovascular Surgery · doi:10.17116/kardio202417031306
Valvular Assessment: Mitral and Aortic Valves
Wakefield, B. J., Holler, K. L., & Trombetta, C. E. (2024) · Springer eBooks · doi:10.1007/978-3-031-45731-9_9
The role of tenascin-C and oxidative stress in rheumatic and congenital heart valve diseases: an observational study
Karataş, Z. (2024) · The Anatolian Journal of Cardiology · doi:10.14744/anatoljcardiol.2013.90846
Aortic Dilatation and Aortopathies in Congenital Heart Disease
Ciancarella, P., Bordonaro, V., & Secinaro, A. (2024) · Springer eBooks · doi:10.1007/978-3-031-52527-8_22
The Association between Aortic Valve Stenosis and a Subsequent Diagnosis of Depression in Germany
Niepmann, S. T., Roderburg, C., Luedde, M., Nickenig, G., Loosen, S. H., & Kostev, K. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13185525
Aortic root replacement for bicuspid aortic valve dysfunction does not impair survival rates
Dolmaci, O. B., van Maasakker, N. E., Poelmann, R. E., Klautz, R. J. M., & Grewal, N. (2024) · Journal of Cardiothoracic Surgery · doi:10.1186/s13019-024-03061-7
Stanford A aortic dissection 40 years after aortic valve replacement with a Starr–Edwards caged-ball prosthesis: a case report
Tokić, T., Hasnas, L., Mikulic, L., Marković, P., Gustek, S., Kucina, A., Jurca, I., Šipuš, D., Mihaljević, M. Z., Gašparović, H., et al. (2024) · Journal of Surgical Case Reports · doi:10.1093/jscr/rjae707
A Rare Case of a Patient with a Myocardial Bridge in Combination with Bicuspid Valve and Subaortic Stenosis
Stoitsev, G. J. (2024) · Acta Medica Bulgarica · doi:10.2478/amb-2024-0079
A Review of Bicuspid Aortic Valve Anomaly
Hu, W., Wang, R., Zhang, Y., Qi, Y., Xu, J., Wang, J., Wang, J., Pu, W., Zhang, Y., Wang, Z., et al. (2025) · International Journal of Clinical Medicine · doi:10.4236/ijcm.2025.161007
Valvular Heart Disease
Simone, A. E. (2025) · Physician Assistant Clinics · doi:10.1016/j.cpha.2024.12.001
Rare gain-of-function regulatory mutations explain the missing heritability of bicuspid aortic valvePreprint
Zhigulev, A., Sjögren, M. P., Buyan, A., Nozdrin, V., Lázár, E., Mauron, R., Lång, K., Spalinskas, R., Schwochow, D., Pradhananga, S., et al. (2025) · medRxiv · doi:10.1101/2025.02.18.25322302
Educational Case: Aortic valve stenosis
Gamss, S., Gurevitz, M. M., Miller, D., & Ziemba, Y. C. (2025) · Academic Pathology · doi:10.1016/j.acpath.2025.100163
Combined Raman Microscopy and Transmission Electron Microscopy shows the co-existence of whitlockite crystals and carbonated hydroxyapatite-mineralized collagen fibrils in human calcified aortic valvesPreprint
van der Meijden, R. H. M., Kuster, C., van Broekhoven, A., Allgayer, R., Rutten, L., Roverts, R., Cerruti, M., Macías‐Sánchez, E., Cornel, J. H., Sommerdijk, N. A. J. M., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.03.641198
Temporal Trends in Etiology of Aortic Valvular Diseases for Patients Undergoing Surgical Valve Replacement: A Report From 40 Years Pathological Experience
Amemiya, K., Ishibashi‐Ueda, H., Ikeda, Y., Matsumoto, M., Ohta‐Ogo, K., Fukushima, S., Fujita, T., & Hatakeyama, K. (2025) · Pathology International · doi:10.1111/pin.70009
Study protocol for an international prospective non-randomized trial evaluating the long-term outcomes of sutureless aortic valve replacement versus stented aortic valve replacement for aortic-valve stenosis in patients at risk to severe valve obstruction: the SAVI-AVR trial
Nappi, F., Salsano, A., Singh, S., El‐Dean, Z., Fiore, A., & Spadaccio, C. (2026) · Journal of Cardiothoracic Surgery · doi:10.1186/s13019-026-04091-z
Study protocol for an internahaational prospective non-randomised trial evaluating the long-term outcomes of transcatheter aortic valve implantation versus surgical aortic valve replacement for aortic-valve stenosis in patients at risk to severe valve obstruction: the TAVISAR trial
Nappi, F., Bourgois, C., Nenna, A., Salsano, A., Schoell, T., El‐Dean, Z., Fiore, A., & Spadaccio, C. (2025) · BMJ Open · doi:10.1136/bmjopen-2025-101417
Estenosis aórtica
Costa, L. C., Guerra, M. J. G., & Teixidor, M. D. (2022) · Actualización en Medicina de Familia · doi:10.55783/amf.180804
Early predictors of aortic valve surgery in patients with significant bicuspid aortic regurgitation without initial surgical indication
Lim, H. J., Kim, K., Gwak, S., Lee, H.-J., Cho, I., Hong, G., Ha, J., & Shim, C. Y. (2025) · Heart · doi:10.1136/heartjnl-2025-325892
Automated detection of bicuspid aortic valve from echocardiographic reports using natural language processing: a large-scale Veterans Affairs studyPreprint
Bowles, A. E., Lynch, J. A., Bermudez, F., Shakt, G. E., DiNatale, T., Pridgen, K. M., Judy, R., Levin, M. G., Hartmann, K., Damrauer, S. M., et al. (2025) · medRxiv · doi:10.1101/2025.06.30.25330573
Endocarditis
Thiene, G., & Basso, C. (2025) · Springer eBooks · doi:10.1007/978-3-031-85589-4_9
Aortic Stenosis and Aortic Incompetence
Tarantini, G., Fabris, T., Fraccaro, C., & Thiene, G. (2025) · Springer eBooks · doi:10.1007/978-3-031-85589-4_7
Genetic Background and Familiarity
Cason, M., Bauce, B., Thiene, G., & Pilichou, K. (2025) · Springer eBooks · doi:10.1007/978-3-031-85589-4_6
Transcatheter Aortic Valve Implantation
Tarantini, G., Fabris, T., Fraccaro, C., & Basso, C. (2025) · Springer eBooks · doi:10.1007/978-3-031-85589-4_14
Embryology of Normal and Bicuspid Valves
Fernández, B., Soto‐Navarrete, M. T., Sans‐Coma, V., & Durán, A. C. (2025) · Springer eBooks · doi:10.1007/978-3-031-85589-4_2
Genetics of Valvular Heart Disease
Knoll, K., & Trenkwalder, T. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-15734-9.00033-9
Von Willebrand Factor Multimers in Aortic Stenosis Surgery: Dynamics and Disease Correlation
Tachioka, S., Kanda, H., Yamakuchi, M., Higashi, S., Suzuki, M., Maywar, D. N., Toyokawa, K., Mukaihara, K., Matsumoto, K., Horiuchi, H., et al. (2025) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.65800
Enhanced Expression of Hemoglobin Scavenger Receptor is Associated With Aortic Valve Stenosis in Patients With Bicuspid Aortic Valve
Matsushita, T., Matsumura, Y., Nakagawa, M., Shimeno, K., Matsumoto, R., Abe, Y., Bito, Y., Aoyama, T., Takahashi, Y., Shibata, T., et al. (2025) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2025.08.025
Lifetime Outcomes Following Intervention for Bicuspid Aortic Valve Stenosis in Childhood
Larsen, A. M., Danford, D. A., Kotula, A. E., & Yetman, A. T. (2025) · Pediatric Cardiology · doi:10.1007/s00246-025-03997-0
A machine learning predictive model based on conventional two-dimensional echocardiography and serum biomarkers for early detection of ascending aorta dilation in BAV patients
Long, X., Niu, Y., Nie, G., He, S., & Na, L. (2025) · Psycho-Oncologie · doi:10.18282/po4573
Is one month of exercise-based cardiac rehabilitation sufficient after surgical aortic valve replacement? A feasibility study of a randomized controlled trial
Schlyter, M., & Hansson, E. E. (2025) · Journal of Rehabilitation Medicine – Clinical Communications · doi:10.2340/jrm-cc.v8.43087
Anomalous origin of right coronary artery with interarterial and intramural course associated with bicuspid aortic valve and dilation of ascending aorta
de Carlos, G. A., Bonezzi, A. C., & Halas, R. (2025) · BMJ Case Reports · doi:10.1136/bcr-2025-267157
Valve interventions for heart failure
Alnoor, M. S., Kunamalla, A., Patel, S., Suradi, H. S., Holzer, R. J., & Hijazi, Z. M. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-13279-7.00069-9
Valvular stenosis and heart failure
Power, A., & Dipchand, A. I. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-13279-7.00001-8
Trends in Bicuspid Aortic Valve–Attributable Death in the United States From 2010 to 2020
Zuin, M., Campia, U., de la Cruz, K. I., Singh, M. N., & Piazza, G. (2025) · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease · doi:10.1161/jaha.125.041725 · Cited by 1
Differences in Severity and Prognosis Between Bicuspid and Tricuspid Severe Aortic Stenosis
Okada, T., Kitai, T., Morimoto, T., Miyakoshi, C., Taniguchi, T., Ota, M., Kato, T., Andò, K., Ohno, N., Kanamori, N., et al. (2025) · JACC Advances · doi:10.1016/j.jacadv.2025.102285
The Role of Systemic Immune-Inflammation Index in Severe Bicuspid Aortic Stenosis
Süygün, H. (2025) · The European Research Journal · doi:10.18621/eurj.1759091
Natural history of unrepaired bicuspid aortic valve at diagnosis: meta-analysis and reconstruction of time-to-event data
Ogami, T., Yokoyama, Y., Sá, M. P., Takagi, H., Fukuhara, S., Sultan, I., & Kuno, T. (2025) · The Journal of Cardiovascular Surgery · doi:10.23736/s0021-9509.25.13258-8
Comparative Outcomes of Balloon-Expandable and Self-Expandable Valves in Transcatheter Aortic Valve Replacement for Bicuspid Aortic Stenosis: A Systematic Review and Meta-Analysis
Bacha, Z., Rath, S., Qadri, M., Alam, U., Ali, M. A., Ahmad, O., Sajjad, F., Khan, K., Noor, H., Javed, J., et al. (2025) · Cardiology in Review · doi:10.1097/crd.0000000000001070
Complex surgical treatment of critical aortic stenosis complicated by multiple organ failure
Romanenko, N. V., Lysenko, A. V., Игоревич, С. Г., Вавилов, А. В., & Sozykin, A. (2025) · Pirogov Russian Journal of Surgery · doi:10.17116/hirurgia2025121162
Amyloids here, amyloids there…What’s wrong with them?
Gharibyan, A. L. (2012) · KTH Publication Database DiVA (KTH Royal Institute of Technology)
Additional file 19 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606473
Additional file 23 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J. T., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606497
Additional file 9 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606443
Additional file 8 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606440
Additional file 6 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606431
Additional file 13 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J. T., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606455
Additional file 22 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606494
Additional file 14 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J. T., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606458
Additional file 18 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606470
Additional file 5 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606428
Additional file 4 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606425
Additional file 24 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606500
Additional file 1 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606416
Additional file 21 of CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J., Wang, B., Li, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26606485

Authors: Siu, S. C., & Silversides, C. K.
Affiliations: Western University (CA)
University Health Network (CA)
Corresponding author: Siu, Samuel C.
ORCID: Siu, Samuel C.
Venue: Journal of the American College of Cardiology
Publisher: Elsevier BV
Published: 2010-06
Volume: 55
Issue: 25
Pages: 2789-2800
ISSN: 0735-1097 (ISSN-L)
DOI: 10.1016/j.jacc.2009.12.068
OpenAlex: W2121967184
Cited by: 1,028
References: 143
Citations by year: 2026: 37 · 2025: 62 · 2024: 59 · 2023: 85 · 2022: 68 · 2021: 100 · 2020: 71 · 2019: 61 · 2018: 63 · 2017: 79 · 2016: 69 · 2015: 67 · 2014: 64 · 2013: 49 · 2012: 57
FWCI: 7.88
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 1178 d)
Locations: Journal of the American College of Cardiology (publishedVersion)
PubMed (publishedVersion)
Scholarship@Western (Western University) (submittedVersion)
Funders: Heart and Stroke Foundation of Canada (NA 5927, NA 5662, T6085)
Canadian Institutes of Health Research (53030, 93722)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Aortic Disease and Treatment Approaches
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Valve Diseases and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
Keywords: bicuspid aortic valve, congenital heart disease, aortic root dilatation, aortic stenosis, aortic incompetence, infective endocarditis, aortic aneurysm, aortic dissection, aortic valve replacement, aortic root surgery, life expectancy, pathobiology, clinical course, surveillance (medicine), medical treatment, intervention timing
MeSH terms: Adult, Aortic Valve, Aortic Valve Insufficiency, Aortic Valve Stenosis, Cause of Death, Combined Modality Therapy, Female, Heart Defects, Congenital, Humans, Magnetic Resonance Imaging, Male, Mitral Valve, Prognosis, Severity of Illness Index, Survival Rate, Echocardiography, Transesophageal, Risk Assessment, Heart Valve Prosthesis Implantation, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Bicuspid Aortic Valve Disease

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks