Cited by 1,028Aortic Disease and Treatment ApproachesCardiac Valve Diseases and TreatmentsCongenital Heart Disease Studies

The DOI matches its Crossref record; 140 of the 143 references it cites were found in a registry or an index.

Bicuspid Aortic Valve Disease

Open access

Siu, Samuel C., Silversides, Candice K.·2010·Journal of the American College of Cardiology

DOI 10.1016/j.jacc.2009.12.068

Open this paper in CoChat — free account Open PDF

Abstract

Bicuspid aortic valve (BAV) disease is the most common congenital cardiac defect. While the BAV can be found in isolation, it is often associated with other congenital cardiac lesions. The most frequent associated finding is dilation of the proximal ascending aorta secondary to abnormalities of the aortic media. Changes in the aortic media are present independent of whether the valve is functionally normal, stenotic, or incompetent. Although symptoms often manifest in adulthood, there is a wide spectrum of presentations ranging from severe disease detected in utero to asymptomatic disease in old age. Complications can include aortic valve stenosis or incompetence, endocarditis, aortic aneurysm formation, and aortic dissection. Despite the potential complications, 2 large contemporary series have demonstrated that life expectancy in adults with BAV disease is not shortened when compared with the general population. Because BAV is a disease of both the valve and the aorta, surgical decision making is more complicated, and many undergoing aortic valve replacement will also need aortic root surgery. With or without surgery, patients with BAV require continued surveillance. Recent studies have improved our understanding of the genetics, the pathobiology, and the clinical course of the disease, but questions are still unanswered. In the future, medical treatment strategies and timing of interventions will likely be refined. This review summarizes our current understanding of the pathology, genetics, and clinical aspects of BAV disease with a focus on BAV disease in adulthood.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.jacc.2009.12.068

Cites

140 of 140 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.176857 · Cited by 8,487
2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.05.007 · Cited by 2,245
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease: Executive Summary
Warnes, C. A., Williams, R. G., Bashore, T. M., CHILD, J. S., Connolly, H. M., Dearani, J. A., del Nido, P. J., Fasules, J. W., Graham, T. P., Hijazi, Z. M., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.190811 · Cited by 2,068
Clinical Factors Associated With Calcific Aortic Valve Disease
Stewart, B. F., Siscovick, D., Lind, B. K., Gardin, J. M., Gottdiener, J. S., Smith, V. E., Kitzman, D. W., & Otto, C. M. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(96)00563-3 · Cited by 2,029
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.05.021 · Cited by 1,702
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease
Warnes, C. A., Williams, R. G., Bashore, T. M., CHILD, J. S., Connolly, H. M., Dearani, J. A., del Nido, P. J., Fasules, J. W., Graham, T. P., Hijazi, Z. M., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.10.001 · Cited by 1,553
Mutations in NOTCH1 cause aortic valve disease
Garg, V., Muth, A. N., Ransom, J. F., Schluterman, M. K., Barnes, R., King, I. N., Grossfeld, P. D., & Srivastava, D. (2005) · Nature · doi:10.1038/nature03940 · Cited by 1,509
Suggested standards for reporting on arterial aneurysms
Johnston, K. W., Rutherford, R. B., Tilson, M. D., Shah, D. M., Hollier, L. H., & Stanley, J. C. (1991) · Journal of Vascular Surgery · doi:10.1067/mva.1991.26737 · Cited by 1,369
Predictors of Outcome in Severe, Asymptomatic Aortic Stenosis
Rosenhek, R., Binder, T. M., Porenta, G., Lang, I. M., Christ, G., SCHEMPER, M., Maurer, G., & Baumgartner, H. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008313430903 · Cited by 1,332
A classification system for the bicuspid aortic valve from 304 surgical specimens
Sievers, H.-H., & Schmidtke, C. (2007) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2007.01.039 · Cited by 1,222

Flagged first, then by citations

Show all 143 references

3 of the 143 references couldn’t be matched to a known paper.

Research works printed but not linked: 4

Osler, 1886, The bicuspid condition of the aortic valve, Trans Assoc Am Physicians, 2, 185
Nadas, 1977, Report from the Joint Study on the Natural History of Congenital Heart Defects, Circulation, 56, I36
Bonow, 2006, J Am Coll Cardiol, 48, e1, 10.1016/j.jacc.2006.05.021 · DOI
Warnes, 2008, J Am Coll Cardiol, 52, e1, 10.1016/j.jacc.2008.10.002 · DOI

Sorted by citations

Items 701–800 of 999

Outcomes of transcatheter vs. surgical aortic valve replacement in bicuspid aortic valve stenosis: A systematic review and meta-analysis
DAS, A. S. H. E. S. H., Gupta, A., Ramamoorthy, L., Benjamin, N. Z. Y., AGRAWAT, D., Pandit, M., Khawar, M. M. H., Chilaka, C., Nyirahabimana, D., Goraga, B., et al. (2026) · Indian Journal of Thoracic and Cardiovascular Surgery · doi:10.1007/s12055-025-02146-9 · Cited by 1
Valve-Dependent Regional Heterogeneity of Wall Mechanics and Collagen Remodeling in Ascending Thoracic Aortic Aneurysms
Radner, C., Schmid, S., Sunderdiek, M., Sitnikova, Y., Hellmich, C., Grefen, L., Grab, M., Buchstab, O., Fabry, T., Sachs, N., et al. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27062658 · Cited by 1
Rare regulatory mutations disrupt mesenchymal molecular programs driving endocardial cushion formation in bicuspid aortic valve
Zhigulev, A., Buyan, A., Lázár, E., Gryzunov, N., Lång, K., Mauron, R., Nozdrin, V., Spalinskas, R., Pradhananga, S., Sjögren, M. P., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-71758-5 · Cited by 1
Measured Versus Predicted Prosthesis–Patient Mismatch after TAVR in Sievers Type 1 BAV: Incidence, Determinants, and Outcomes From the AD-HOC Registry
Fabris, T., Arturi, F., Buono, A., Biase, C. D., Bellamoli, M., Zito, A., Mangieri, A., Montarello, N. J., Costa, G., Alfadhel, M., et al. (2026) · Circulation Cardiovascular Interventions · doi:10.1161/circinterventions.125.015994 · Cited by 1
Surgical Versus Transcatheter Aortic Valve Replacement in Bicuspid Aortic Stenosis: 1‐Year Clinical Outcomes in Patients Aged 65 Years and Older
Hemelrijk, K. I., Mon-Noboa, M., Tirado‐Conte, G., Winkelman, J. A., Asmarats, L., Roselló-Díez, E., Pérez-Camargo, D., Kobari, Y., Guitteny, T., McInerney, A., et al. (2026) · Journal of the American Heart Association · doi:10.1161/jaha.125.045763 · Cited by 1
Bicuspid aortic valve stenosis is characterized by increased angiogenesis, inflammation, and a higher valvular-to-systemic calcification ratio than tricuspid aortic valve stenosis
Brückner, A., Brandtner, A. T., Rieck, S., Billig, H., Masson, W., Weber, A. K., Bakhtiary, F., Röll, W., Bourauel, C., Schildberg, F. A., et al. (2026) · Basic Research in Cardiology · doi:10.1007/s00395-026-01191-8 · Cited by 1
Phase-contrast MRI assessment of the thoracic aortic wall shear stress association with ascending aortic progression
Ye, Y., Zeng, T., Chen, Y., Ding, B., Huang, Y.-J., Shi, J., & Huang, J.-M. (2026) · Biomedizinische Technik/Biomedical Engineering · doi:10.1515/bmt-2026-0247 · Cited by 1
Long-Term Outcomes of Contemporary Balloon-Expandable TAVR in Bicuspid Aortic Valve
Suruga, K., Patel, V., Shitan, H., Guo, Y., Nagasaka, T., Ng, D., Menda, J., Singh, A., Goyal, A., Buss, E., et al. (2026) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2026.06.015 · Cited by 1
Factors other than genotype account largely for the phenotypic variation of the pulmonary valve in Syrian hamsters
Fernández, M. C., Durán, A. C., Fernández, B., Arqué, J., Anderson, R., & Sans-Coma, V. (2012) · Journal of Anatomy · doi:10.1111/j.1469-7580.2012.01512.x · Cited by 3
s A fatal outcome of thoracic aortic aneurysm in a male patient with bicuspid aortic valve
Milanowska, B., Michalak, E., Michałowska, I. M., Szpakowski, E., Konopka, A., Klisiewicz, A., & Bilińska, Z. T. (2013) · Advances in Interventional Cardiology · doi:10.5114/pwki.2013.37507 · Cited by 1
Bicuspidie aortique : diagnostic et prise en charge
Tribouilloy, C. (2012) · Archives des Maladies du Coeur et des Vaisseaux - Pratique · doi:10.1016/s1261-694x(12)70348-6 · Cited by 1
Experiencia de la implantación de válvulas aórticas transcatéter en el Hospital Central Militar
Martín-Hernández, P., Gutiérrez-Leonard, H., Ojeda-Delgado, J. L., Fagoaga-Valdivia, J., Nanni, R. B., Rodríguez-Somarriba, M., Páez-Lizárraga, L. M., Berúmen-Domínguez, L. E., Hernández-Jiménez, L., Rebollo-Hurtado, V., et al. (2015) · Archivos de cardiología de México · doi:10.1016/j.acmx.2015.07.004 · Cited by 1
Valvular Heart Disease: Introduction, Clinical Pathogenesis, and Management
Kunchakarra, S., Puthumana, J. J., & Maganti, K. (2015) · Springer eBooks · doi:10.1007/978-3-319-15961-4_54 · Cited by 1
Experimental cardiovascular and lung research Impact of geometric changes in a dilated aorta with a bicuspid aortic valve on blood flow disturbances – a numerical modeling study
Małota, Z., Głowacki, J., Kukulski, T., & Sadowski, W. (2013) · Polish Journal of Cardio-Thoracic Surgery · doi:10.5114/kitp.2013.38101 · Cited by 1
Transcatheter aortic valve implantation in patients with bicuspid aortic valve
Ding, J., Zhu, J. H., Lü, J., Ding, X., Zhang, X., & Ma, G. (2016) · Cor et Vasa · doi:10.1016/j.crvasa.2016.06.001 · Cited by 1
Bicuspid Aortic Valve
Verstraeten, A., Roos‐Hesselink, J. W., & Loeys, B. (2016) · Springer eBooks · doi:10.1007/978-3-319-44203-7_18 · Cited by 1
Imaging: Echo, CT and MRI
Guo, K. W. Q., Lath, N., & Tan, J. L. (2017) · Springer eBooks · doi:10.1007/978-4-431-56071-5_6 · Cited by 1
Valvular Heart Disease
Carabello, B. A. (2012) · Goldman's Cecil Medicine · doi:10.1016/b978-1-4377-1604-7.00075-0 · Cited by 1
Paravalvular Leakage After Transcatheter Aortic Valve Implantation
Rahhab, Z., & Mieghem, N. M. V. (2017) · Springer eBooks · doi:10.1007/978-981-10-5400-6_9 · Cited by 1
Cardiovascular Considerations in the Female Athlete
White, S. C., Goldberg, J. M., & Battle, R. W. (2017) · Clinics in Sports Medicine · doi:10.1016/j.csm.2017.05.008 · Cited by 1
Myocardial hypertrophy and intracardial hemodynamics in children with bicuspid aortic valve
Каmеnshchyk, A. V., & Іванько, О. Г. (2017) · Pathologia · doi:10.14739/2310-1237.2017.2.109296 · Cited by 1
Bicuspid Aortic Valve
Yıldırım, A., & Karaağaç, A. T. (2018) · InTech eBooks · doi:10.5772/intechopen.76643 · Cited by 1
Comprehensive Approach to Aortic Valve Disease
Carabello, B. A., Alwair, H., & Nekkanti, R. (2019) · Cardiovascular medicine · doi:10.1007/978-1-4471-2840-3_5 · Cited by 1
Aortic Root Reconstruction
Altarabsheh, S. E., Deo, S. V., & Elgudin, Y. E. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.86034 · Cited by 1
Clinical impact of pathology-proven etiology of severely stenotic aortic valves on mid-term outcomes in patients undergoing surgical aortic valve replacement
Miura, S., Inoue, K., Kumamaru, H., Yamashita, T., Hanyu, M., Shirai, S., & Andò, K. (2020) · PLoS ONE · doi:10.1371/journal.pone.0229721 · Cited by 1
Bicuspid aortic valve
Strinić, D., Friščić, T., Habek, J. Č., & Šikić, J. (2021) · Cardiologia Croatica · doi:10.15836/ccar2021.305 · Cited by 1
Bicuspid aortic valve: what should I know? Updated review of its clinical and pathophysiological aspects
Junco-Vicente, A., Rodrı́guez, I., Solache-Berrocal, G., Cigarrán, H., & Martı́n, M. (2021) · Archivos de cardiolog�a de M�xico (English ed Internet) · doi:10.24875/acme.m20000158 · Cited by 1
A Left ventricle remodeling in patients with bicuspid aortic valve
Suwa, K., Rahsepar, A. A., Geiger, J., Dolan, R. S., Ghasemiesfe, A., Barker, A. J., Collins, J. D., Markl, M., & Carr, J. (2022) · The International Journal of Cardiovascular Imaging · doi:10.1007/s10554-022-02727-4 · Cited by 1
Variability in surveillance practice for patients with diagnosis of bicuspid aortic valve syndrome
Kahler‐Quesada, A., Vallabhajosyula, I., Yousef, S., Mori, M., Amabile, A., Assi, R., Geirsson, A., & Vallabhajosyula, P. (2022) · Scientific Reports · doi:10.1038/s41598-022-25571-x · Cited by 1
Genetics and Genomics of Congenital and Acquired Cardiovascular Disease
Martinez, H. R., Beasley, G. S., Jefferies, J. L., & Towbin, J. A. (2020) · Springer eBooks · doi:10.1007/978-1-4471-4999-6_89-2 · Cited by 1
Bacterial Culture-Negative Acute Infective Endocarditis With Vegetation in Native Bicuspid Aortic Valve
Sunnaa, M., Dhawan, R., Tabachnick, D. R., & Attanasio, S. (2023) · Cureus · doi:10.7759/cureus.35101 · Cited by 1
Iatrogenic or predetermined aortic dysplasia?
Wang, Z., Wang, Q., & Zhu, X. (2023) · Cardiology in the Young · doi:10.1017/s104795112200419x · Cited by 1
Comparison of patients with bicuspid and tricuspid aortic valve in transcatheter aortic valve implantation
Zhu, Z., Xiong, T., & Chen, M. (2023) · Expert Review of Medical Devices · doi:10.1080/17434440.2023.2184686 · Cited by 1
Unlocking the potential of induced pluripotent stem cells for neonatal disease modeling and drug development
Liu, Z., Lami, B., Ikonomou, L., & Gu, M. (2023) · Seminars in Perinatology · doi:10.1016/j.semperi.2023.151729 · Cited by 1
Left ventricular strain in pediatric patients with bicuspid aortic valves and aortopathy
Frye, R., Ittleman, B. R., Shabanova, V., Sugeng, L., Steele, J., Ferdman, D. J., & Karnik, R. (2023) · Progress in Pediatric Cardiology · doi:10.1016/j.ppedcard.2023.101636 · Cited by 1
Obstetrical and neonatal outcomes in patients with surgically repaired heart disease
Laird, A. C., Kumnick, A. R., Fries, M. H., & Chornock, R. L. (2024) · American Journal of Obstetrics & Gynecology MFM · doi:10.1016/j.ajogmf.2024.101323 · Cited by 1
Molecular Pathways and Animal Models of Semilunar Valve and Aortic Arch Anomalies
Gill, E. K., & Bamforth, S. D. (2024) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-44087-8_46 · Cited by 1
Transcatheter aortic valve implantation in patients with bicuspid aortic valve (literature review)
Mkrtychev, D. S., Komlev, A. E., Колегаев, А. С., & Эмвярович, И. Т. (2024) · Сибирский журнал клинической и экспериментальной медицины · doi:10.29001/2073-8552-2024-39-2-28-35 · Cited by 1
Global research landscape on the genetics of congenital heart disease: A bibliometric and visualized analysis via VOSviewer and CiteSpace
Zhang, F., Qi, L., Zhao, M., Han, S., Zhang, H., & Wang, G. (2024) · Medicine · doi:10.1097/md.0000000000040261 · Cited by 2
The Combined Risk of Marfan Syndrome and Bicuspid Aortic Valve in the Elderly
McPherson, R. J., Shehata, M., & Izquierdo-Pretel, G. (2025) · Cureus · doi:10.7759/cureus.81314 · Cited by 1
Implications of monogenic bicuspid aortic valve (BAV) forms among sporadic BAV patients
Bruenger, C. M. H., Oeffner, F., Koebbe, L. L., Zimmer, S., Veulemans, V., Adam, M., Bigge, J., Heilmann‐Heimbach, S., Kelm, M., Baldus, S. E., et al. (2025) · European Journal of Human Genetics · doi:10.1038/s41431-025-01909-7 · Cited by 1
The Bicuspid Aortic Valve and Associated Aortic Disease
Braverman, A. C. (2014) · Elsevier eBooks · doi:10.1016/b978-1-4557-4860-0.00013-x · Cited by 1
Management of severe aortic valve stenosis in the neonate
Mitchell, B. J., & Brown, S. C. (2017) · SA Heart · doi:10.24170/11-1-1766 · Cited by 1
Congenital Heart Defects That Include Cardiac Valve Abnormalities
Bryant, R. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6144-9_3 · Cited by 1
Congenital bicuspid aortic valve: steps toward providing an answer to the question of antibiotic endocarditis prophylaxis
Wolfson, A., DeCara, J. M., & Bowman, M. A. H. (2015) · Case Reports in Internal Medicine · doi:10.5430/crim.v2n3p73 · Cited by 1
Clinical and Genetic Aspects of Bicuspid Aortic Valve: A Proposed Model for Family Screening Based on a Review of Literature
Baars, H. F., Overwater, E., Baars, M. J. H., Mulder, B. J. M., Kerstjens‐Frederikse, W. S., van Engelen, K., & Houweling, A. C. (2015) · Cardiogenetics · doi:10.4081/cardiogenetics.2015.4842 · Cited by 1
Bicuspidie aortique et pratique du sport
Carré, F. (2013) · Archives des Maladies du Coeur et des Vaisseaux - Pratique · doi:10.1016/s1261-694x(13)70471-1 · Cited by 1
Bicuspid aortic and pulmonary valves complicated by acute aortic dissection in a highly trained athlete – Case report and review of the literature
Janík, M., Novomesky, F., Straka, L., Krajčovič, J., Stuller, F., & Hejna, P. (2014) · Romanian Journal of Legal Medicine · doi:10.4323/rjlm.2014.167 · Cited by 1
Aneurysmatic aortic root in bicuspid aortic valve stenosis: mini-invasive approach with sutureless prosthesis
Pollari, F., Santarpino, G., Pfeiffer, S., & Fischlein, T. J. M. (2015) · Monaldi Archives for Chest Disease · doi:10.4081/monaldi.2014.53 · Cited by 1
Computed Tomographic Angiography in the Assessment of Congenital Heart Disease and Coronary Artery Anomalies
Pillutla, P., & Cook, S. C. (2016) · Springer eBooks · doi:10.1007/978-3-319-28219-0_23 · Cited by 1
Emerging Clinical Applications of 4D Flow MR in the Heart and Aorta
Owen, J. W., & Raptis, C. A. (2016) · Current Radiology Reports · doi:10.1007/s40134-016-0188-2 · Cited by 1
Congenital biscuspid aortic valve in pediatric and early adults: Does valvular phenotype affect other parameters?
Behairy, N. H. E. D., Saraya, S., Kharabish, A. E., Elkaffas, S. M. H., & Ramadan, A. (2017) · The Egyptian Journal of Radiology and Nuclear Medicine · doi:10.1016/j.ejrnm.2017.07.002 · Cited by 1
Determination of signal calcineurin pathway biomarkers significance in early myocardial changes in children with bicuspid aortic valve
Kamenshchyk, A. V. (2017) · ScienceRise Medical Science · doi:10.15587/2519-4798.2017.116752 · Cited by 1
Hipoplasia de la valva posterior de la válvula mitral y válvula aórtica bicúspide. Una muy rara asociación para encontrar en un paciente adulto
Sánchez-Solanilla, L. F., Zuluaga-Rojas, J. F., & Rodríguez-Martin, J. (2018) · Revista Colombiana de Cardiología · doi:10.1016/j.rccar.2018.04.005 · Cited by 1
Technical solution during challenging implantation of CoreValve Evolut R 34 prosthesis in patient with bicuspid aortic valve with large annulus
Chodór, P., Wilczek, K. L., Chodór-Rozwadowska, K., Przybylski, A., Zembala, M., & Kalarus, Z. F. (2018) · Advances in Interventional Cardiology · doi:10.5114/aic.2018.79875 · Cited by 1
Aortic Valvular Heart Disease
Ko, S. M. (2014) · Springer eBooks · doi:10.1007/978-3-642-36397-9_17 · Cited by 1
Inflammatory and Connective Tissue Disorders of the Aorta
Panico, B. S., Panico, A. F., & Dieter, R. S. (2019) · Springer eBooks · doi:10.1007/978-3-030-11322-3_16 · Cited by 1
Bicuspid Aortic Valve and Aortopathy
Patlolla, S. H., & Schaff, H. V. (2020) · Springer eBooks · doi:10.1007/978-3-030-24174-2_39 · Cited by 1
Congenital bicuspid aortic valve: Differential prevalence across different South African population groups
Hunter, L. D., Lloyd, G., Monaghan, M. J., Pecoraro, A. J. K., Doubell, A. F., & Herbst, P. G. (2020) · South African Medical Journal · doi:10.7196/samj.2020.v110i8.14854 · Cited by 1
Transcatheter heart valve implant in bicuspid aortic valves with large annuli
Goel, P. K., Khanna, R., Sahu, A. K., & Jain, N. (2021) · IHJ Cardiovascular Case Reports (CVCR) · doi:10.1016/j.ihjccr.2020.12.011 · Cited by 1
Overview of Aortic Stenosis
Arko, R., & Fankhanel, C. (2021) · Physician Assistant Clinics · doi:10.1016/j.cpha.2020.11.004 · Cited by 1
Choosing Between Transcatheter Aortic Valve Replacement and Surgery in the Low-Risk Transcatheter Aortic Valve Replacement Era
Kang, G., & Yeung, A. C. (2021) · Interventional Cardiology Clinics · doi:10.1016/j.iccl.2021.05.001 · Cited by 1
Endocarditis infecciosa y cardiopatía congénita
Filippo, S. D. (2022) · EMC - Pediatría · doi:10.1016/s1245-1789(22)46104-x · Cited by 1
The association of bicuspid aortic valve on long-term outcome following one-stage repair of aortic arch obstruction associated with ventricular septal defect
Rahatianpur, M., Bakhtiary, F., Vázquez-Jiménez, J. F., Dähnert, I., & Kostelka, M. (2023) · RWTH Publications (RWTH Aachen) · Cited by 1
Aortic Valve Regurgitation
Evangelista, A., & Galián-Gay, L. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-40125-8.00017-2 · Cited by 1
Diseases of the Aorta
Dudzinski, D. M., Isselbacher, E. M., & Paruchuri, K. (2020) · Springer eBooks · doi:10.1007/978-3-030-45792-1_14 · Cited by 1
Adult Congenital Heart Disease (ACHD)
Pizarro, C., & Chowdhury, D. (2022) · Revista Médica Clínica Las Condes · doi:10.1016/j.rmclc.2022.04.002 · Cited by 1
Computed Tomographic Evaluation of Congenital Left Ventricular Outflow Obstruction
Kumar, P., Bhatia, M., & Arora, N. (2023) · Current Cardiology Reviews · doi:10.2174/1573403x19666230525144602 · Cited by 1
Aortopathy in Adults with Congenital Heart Disease
Zaidi, A. N., Kay, W. A., & Daniels, C. J. (2013) · Springer eBooks · doi:10.1007/978-1-4471-4619-3_192 · Cited by 1
Letter in response to “Acute Coronary Involvement in Acute Type A Aortic Dissection: A Subgroup Analysis of Bicuspid Aortic Valve and Marfan Syndrome”
Chien, T., Chen, C.-W., Yu, C.-P., Chen, H., & Chen, Y. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2013.12.198 · Cited by 1
Biomechanical modeling and hemorheological assessment of ascending thoracic aortic aneurysm, aortic heart valve, and blood clot
Yeh, H. H. (2019) · cIRcle (University of British Columbia) · doi:10.14288/1.0384818 · Cited by 1
A Patient-Specific Model of Transcatheter Valve Replacement in a Bicuspid Heart ValvePreprint
McGee, O. M., McNamara, A., & McNamara, L. M. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.03.05.433633 · Cited by 1
Congenital Heart Disease
Martin, L. J., & Benson, D. W. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-382227-7.00054-9 · Cited by 1
Valvular Heart Disease
Singh, T. K. (2021) · Springer eBooks · doi:10.1007/978-3-030-69384-8_6 · Cited by 1
RAGE antagonist peptide mitigates AGE-mediated endothelial hyperpermeability and accumulation of glycoxidation products in human ascending aortas and in a murine model of aortic aneurysmPreprint
Camillo, C., Abramov, A., Allen, P., Castillero, E., Roberts, E., Xue, Y., Frasca, A., Moreno, V., Kurade, M., Robinson, K., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.10.22.465199 · Cited by 1
Bicuspid aortic valve
Weerakkody, Y., Feger, J., & Campos, A. (2012) · Radiopaedia.org · doi:10.53347/rid-16604 · Cited by 1
Editorial: Bicuspid aortic valve: from pathophysiological mechanisms, imaging diagnosis to clinical treatment methods
Zhang, Y., Xiong, T., Søndergård, L., Mylotte, D., Piazza, N., Prendergast, B., & Chen, M. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1193544 · Cited by 1
Cardiac Function and Aortic Valve Intervention : Echocardiographic Studies of Myocardial Recovery in Patients with Severe Aortic Valve Disease
Forsberg, L. M. (2012) · DiVA (Linkoping University) · Cited by 1
Prevention of Infective Endocarditis in Patients with Congenital Heart Disease
Filippo, S. D. (2013) · Springer eBooks · doi:10.1007/978-1-4471-4619-3_3
The Aortopathy of Bicuspid Aortic Valves
Siddiqi, O. K., & KLEIN, M. D. (2014) · Springer eBooks · doi:10.1007/978-1-4471-5622-2_3
Surgical Treatment of Bicuspid Aortic Valve Disease
Chen, Y., & Lee, S.-T. (2011) · InTech eBooks · doi:10.5772/19929
Congenital Aortic Stenosis in Childhood
Crespo, D., & Dahdah, N. (2011) · InTech eBooks · doi:10.5772/22982
Abnormalities of Left Ventricular Inflow and Outflow
Banka, P., & Geva, T. (2012) · Springer eBooks · doi:10.1007/978-1-4471-4267-6_9
Phenotype and genotype effects on the transcriptome in cardiovascular disease - tools to identify candidate genes
Folkersen, L. (2011) · Figshare
Heart Valve Tissue Engineering: A Study of Time Varying Effects and Sample Geometry
Salinas, M. (2011) · doi:10.25148/etd.fi11120806
Vascular function in bicuspid aortic valve disease
Petrini, J. (2014) · Figshare
Surgical Management of the Aortic Root
Goslin, B. J., & Hooker, R. L. (2012) · InTech eBooks · doi:10.5772/51831
Left Ventricular Outflow Regurgitation and Aortoventricular Tunnel
Joshi, V. M., & McKay, R. (2012) · doi:10.1002/9781444398786.ch31
Patient Study 38
Saksena, F. B. (2015) · doi:10.1002/9781118469767.ch38
Congenital Heart Disease: Pregnancy and Contraception
Hatton, R., Colman, J. M., Sermer, M., Siu, S. C., & Silversides, C. K. (2013) · Springer eBooks · doi:10.1007/978-1-4471-4441-0_34
Self-citation
Left Ventricular Outflow Tract Abnormalities
Mazur, W. M., Siegel, M. J., Miszalski−Jamka, T., & Pelberg, R. A. (2013) · Springer eBooks · doi:10.1007/978-1-4471-5088-6_13
Ósæðarlokuskipti vegna ósæðarlokuþrengsla á Íslandi 2007-2009
Helgason, D. (2012)
Response to Letter Regarding Article, “A Word of Caution: Risk of Device Erosion After Percutaneous Treatment of Atrial Septal Defect in Patients With Dilated Aortic Root”
Dardas, P. S., Thanopoulos, V. D., Theofilogiannakos, E. K., Ninios, V. N., Kallifatidis, A., & Pitsis, A. A. (2015) · Circulation · doi:10.1161/circulationaha.114.012782
Worsening Behavioral Dysregulation in a Triplet Pair: Undertreated Attention-Deficit/Hyperactivity Disorder or Untreated Psychiatric Comorbid Disorders?
Mitrani, P., & Coffey, B. (2013) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2013.2303
Anomalies congénitales de la voie aortique. Sténoses aortiques congénitales
Bouzguenda, I. (2012) · EMC - Cardiologie · doi:10.1016/s1166-4568(12)32812-x
Aortas reveal the myth of male privilege
Luft, F. C. (2014) · Journal of Molecular Medicine · doi:10.1007/s00109-014-1196-4
Embriogeneza i anatomia wad lewej części serca
Koleśnik, A., & Niszczota, C. S. (2012) · Pediatria Polska · doi:10.1016/j.pepo.2012.09.010
Estudio de la agregación familiar de pacientes con válvula aórtica bicúspide
Robledo-Carmona, J., & Rodríguez–Bailón, I. (2012) · Cardiocore · doi:10.1016/j.carcor.2011.11.001
Congenital Aortic Stenosis and Aneurysms
van der Linde, D. (2013)
Chapitre 24 – Imagerie des anomalies congénitales de l'aorte chez l'enfant et chez l'adulte
Macron, L., & Ladouceur, M. (2015) · doi:10.1016/b978-2-294-71485-6.00024-7

Authors: Siu, S. C., & Silversides, C. K.
Affiliations: Western University (CA)
University Health Network (CA)
Corresponding author: Siu, Samuel C.
ORCID: Siu, Samuel C.
Venue: Journal of the American College of Cardiology
Publisher: Elsevier BV
Published: 2010-06
Volume: 55
Issue: 25
Pages: 2789-2800
ISSN: 0735-1097 (ISSN-L)
DOI: 10.1016/j.jacc.2009.12.068
OpenAlex: W2121967184
Cited by: 1,028
References: 143
Citations by year: 2026: 37 · 2025: 62 · 2024: 59 · 2023: 85 · 2022: 68 · 2021: 100 · 2020: 71 · 2019: 61 · 2018: 63 · 2017: 79 · 2016: 69 · 2015: 67 · 2014: 64 · 2013: 49 · 2012: 57
FWCI: 7.88
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 1178 d)
Locations: Journal of the American College of Cardiology (publishedVersion)
PubMed (publishedVersion)
Scholarship@Western (Western University) (submittedVersion)
Funders: Heart and Stroke Foundation of Canada (NA 5927, NA 5662, T6085)
Canadian Institutes of Health Research (53030, 93722)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Aortic Disease and Treatment Approaches
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Valve Diseases and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
Keywords: bicuspid aortic valve, congenital heart disease, aortic root dilatation, aortic stenosis, aortic incompetence, infective endocarditis, aortic aneurysm, aortic dissection, aortic valve replacement, aortic root surgery, life expectancy, pathobiology, clinical course, surveillance (medicine), medical treatment, intervention timing
MeSH terms: Adult, Aortic Valve, Aortic Valve Insufficiency, Aortic Valve Stenosis, Cause of Death, Combined Modality Therapy, Female, Heart Defects, Congenital, Humans, Magnetic Resonance Imaging, Male, Mitral Valve, Prognosis, Severity of Illness Index, Survival Rate, Echocardiography, Transesophageal, Risk Assessment, Heart Valve Prosthesis Implantation, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Bicuspid Aortic Valve Disease

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks