Cited by 1,028Aortic Disease and Treatment ApproachesCardiac Valve Diseases and TreatmentsCongenital Heart Disease Studies

The DOI matches its Crossref record; 140 of the 143 references it cites were found in a registry or an index.

Bicuspid Aortic Valve Disease

Open access

Siu, Samuel C., Silversides, Candice K.·2010·Journal of the American College of Cardiology

DOI 10.1016/j.jacc.2009.12.068

Open this paper in CoChat — free account Open PDF

Abstract

Bicuspid aortic valve (BAV) disease is the most common congenital cardiac defect. While the BAV can be found in isolation, it is often associated with other congenital cardiac lesions. The most frequent associated finding is dilation of the proximal ascending aorta secondary to abnormalities of the aortic media. Changes in the aortic media are present independent of whether the valve is functionally normal, stenotic, or incompetent. Although symptoms often manifest in adulthood, there is a wide spectrum of presentations ranging from severe disease detected in utero to asymptomatic disease in old age. Complications can include aortic valve stenosis or incompetence, endocarditis, aortic aneurysm formation, and aortic dissection. Despite the potential complications, 2 large contemporary series have demonstrated that life expectancy in adults with BAV disease is not shortened when compared with the general population. Because BAV is a disease of both the valve and the aorta, surgical decision making is more complicated, and many undergoing aortic valve replacement will also need aortic root surgery. With or without surgery, patients with BAV require continued surveillance. Recent studies have improved our understanding of the genetics, the pathobiology, and the clinical course of the disease, but questions are still unanswered. In the future, medical treatment strategies and timing of interventions will likely be refined. This review summarizes our current understanding of the pathology, genetics, and clinical aspects of BAV disease with a focus on BAV disease in adulthood.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.jacc.2009.12.068

Cites

140 of 140 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.176857 · Cited by 8,487
2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.05.007 · Cited by 2,245
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease: Executive Summary
Warnes, C. A., Williams, R. G., Bashore, T. M., CHILD, J. S., Connolly, H. M., Dearani, J. A., del Nido, P. J., Fasules, J. W., Graham, T. P., Hijazi, Z. M., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.190811 · Cited by 2,068
Clinical Factors Associated With Calcific Aortic Valve Disease
Stewart, B. F., Siscovick, D., Lind, B. K., Gardin, J. M., Gottdiener, J. S., Smith, V. E., Kitzman, D. W., & Otto, C. M. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(96)00563-3 · Cited by 2,029
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.05.021 · Cited by 1,702
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease
Warnes, C. A., Williams, R. G., Bashore, T. M., CHILD, J. S., Connolly, H. M., Dearani, J. A., del Nido, P. J., Fasules, J. W., Graham, T. P., Hijazi, Z. M., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.10.001 · Cited by 1,553
Mutations in NOTCH1 cause aortic valve disease
Garg, V., Muth, A. N., Ransom, J. F., Schluterman, M. K., Barnes, R., King, I. N., Grossfeld, P. D., & Srivastava, D. (2005) · Nature · doi:10.1038/nature03940 · Cited by 1,509
Suggested standards for reporting on arterial aneurysms
Johnston, K. W., Rutherford, R. B., Tilson, M. D., Shah, D. M., Hollier, L. H., & Stanley, J. C. (1991) · Journal of Vascular Surgery · doi:10.1067/mva.1991.26737 · Cited by 1,369
Predictors of Outcome in Severe, Asymptomatic Aortic Stenosis
Rosenhek, R., Binder, T. M., Porenta, G., Lang, I. M., Christ, G., SCHEMPER, M., Maurer, G., & Baumgartner, H. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008313430903 · Cited by 1,332
A classification system for the bicuspid aortic valve from 304 surgical specimens
Sievers, H.-H., & Schmidtke, C. (2007) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2007.01.039 · Cited by 1,222

Flagged first, then by citations

Show all 143 references

3 of the 143 references couldn’t be matched to a known paper.

Research works printed but not linked: 4

Osler, 1886, The bicuspid condition of the aortic valve, Trans Assoc Am Physicians, 2, 185
Nadas, 1977, Report from the Joint Study on the Natural History of Congenital Heart Defects, Circulation, 56, I36
Bonow, 2006, J Am Coll Cardiol, 48, e1, 10.1016/j.jacc.2006.05.021 · DOI
Warnes, 2008, J Am Coll Cardiol, 52, e1, 10.1016/j.jacc.2008.10.002 · DOI

Sorted by citations

Items 101–200 of 999

4D Flow Analysis of BAV-Related Fluid-Dynamic Alterations: Evidences of Wall Shear Stress Alterations in Absence of Clinically-Relevant Aortic Anatomical Remodeling
Piatti, F., Sturla, F., Bissell, M. M., Pirola, S., Lombardi, M., Nesteruk, I. G., Corte, A. D., Redaelli, A. C. L., & Votta, E. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00441 · Cited by 65
Incidence, morphology, and progression of bicuspid aortic valve in pediatric and young adult subjects with coexisting congenital heart defects
Niaz, T., Poterucha, J. T., Johnson, J. N., Craviari, C., Nienaber, T., Palfreeman, J., Cetta, F., & Hagler, D. J. (2016) · Congenital Heart Disease · doi:10.1111/chd.12429 · Cited by 63
Epidemiology of Valvular Heart Disease
Peters, A. S., Duggan, J. P., Trachiotis, G. D., & Antevil, J. L. (2022) · Surgical Clinics of North America · doi:10.1016/j.suc.2022.01.008 · Cited by 69
Specific circulating microRNA signature of bicuspid aortic valve disease
Martínez-Micaelo, N., Beltrán‐Debón, R., Baiges, I., Faiges, M., & Alegret, J. M. (2017) · Journal of Translational Medicine · doi:10.1186/s12967-017-1176-x · Cited by 63
The Inter-Relationship of Periostin, TGFβ, and BMP in Heart Valve Development and Valvular Heart Diseases
Conway, S. J., Doetschman, T., & Azhar, M. (2011) · The Scientific World JOURNAL · doi:10.1100/tsw.2011.132 · Cited by 62
Bicuspid Aortic Valve: a Review with Recommendations for Genetic Counseling
Freeze, S. L., Landis, B. J., Ware, S. M., & Helm, B. M. (2016) · Journal of Genetic Counseling · doi:10.1007/s10897-016-0002-6 · Cited by 66
Etiology of bicuspid aortic valve disease: Focus on hemodynamics
Atkins, S. K. (2014) · World Journal of Cardiology · doi:10.4330/wjc.v6.i12.1227 · Cited by 61
Slit–Robo signalling in heart development
Zhao, J., & Mommersteeg, M. T. M. (2018) · Cardiovascular Research · doi:10.1093/cvr/cvy061 · Cited by 61
Aortic valve stenosis and aortic diameters determine the extent of increased wall shear stress in bicuspid aortic valve disease
Farag, E. S., van Ooij, P., Planken, R. N., Dukker, K. C. P., de Heer, F., Bouma, B. J., Robbers‐Visser, D., Groenink, M., Nederveen, A. J., de Mol, B. A. J. M., et al. (2018) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.25956 · Cited by 61
Molecular and developmental mechanisms of congenital heart valve disease
Lincoln, J., & Yutzey, K. E. (2011) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.20799 · Cited by 60
2014 ESC Guidelines on the Diagnosis and Treatment of Aortic Diseases
Erbel, R., Aboyans, V., Boileau, C., Bossone, E., Bartolomeo, R. D., Eggebrecht, H., Evangelista, A., Falk, V., Frank, H., Gaemperli, O., et al. (2015) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2014.12.005 · Cited by 62
The genetic and molecular basis of bicuspid aortic valve associated thoracic aortopathy: a link to phenotype heterogeneity.
Padang, R., Bannon, P. G., Jeremy, R., Richmond, D., Semsarian, C., Vallely, M. P., Wilson, M. K., & Yan, T. D. (2013) · Europe PMC (PubMed Central) · doi:10.3978/j.issn.2225-319x.2012.11.17 · Cited by 61
Society for Cardiovascular Magnetic Resonance/European Society of Cardiovascular Imaging/American Society of Echocardiography/Society for Pediatric Radiology/North American Society for Cardiovascular Imaging Guidelines for the Use of Cardiac Magnetic Resonance in Pediatric Congenital and Acquired Heart Disease: Endorsed by The American Heart Association
Fogel, M. A., Anwar, S., Broberg, C. S., Browne, L. P., Chung, T., Johnson, T. R., Muthurangu, V., Taylor, M. D., Valsangiacomo-Buechel, E., & Wilhelm, C. M. (2022) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.122.014415 · Cited by 60
Pathogenesis of aortic stenosis: not just a matter of wear and tear.
Sverdlov, A. L., Ngo, D. T. M., Chapman, M., Ali, O. A., Chirkov, Y. Y., & Horowitz, J. D. (2011) · Europe PMC (PubMed Central) · Cited by 58
NOing the heart: Role of nitric oxide synthase-3 in heart development
Liu, Y., & Feng, Q. (2012) · Differentiation · doi:10.1016/j.diff.2012.04.004 · Cited by 63
Simulations of morphotype-dependent hemodynamics in non-dilated bicuspid aortic valve aortas
Cao, K., Atkins, S. K., McNally, A., Liu, J., & Sucosky, P. (2016) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2016.11.024 · Cited by 58
Krox20 defines a subpopulation of cardiac neural crest cells contributing to arterial valves and bicuspid aortic valve
Odelin, G., Faure, E., Coulpier, F., Bonito, M. D., Bajolle, F., Studer, M., Aviérinos, J.-F., Charnay, P., Topilko, P., & Zaffran, S. (2017) · Development · doi:10.1242/dev.151944 · Cited by 58
Deficiency of Natriuretic Peptide Receptor 2 Promotes Bicuspid Aortic Valves, Aortic Valve Disease, Left Ventricular Dysfunction, and Ascending Aortic Dilatations in Mice
Blaser, M. C., Wei, K., Adams, R. L. E., Zhou, Y., Caruso, L.-L., Mirzaei, Z., Lam, A. Y. L., Tam, R. K. K., Zhang, H., Heximer, S. P., et al. (2017) · Circulation Research · doi:10.1161/circresaha.117.311194 · Cited by 60
Systolic Flow Displacement Correlates With Future Ascending Aortic Growth in Patients With Bicuspid Aortic Valves Undergoing Magnetic Resonance Surveillance
Burris, N. S., Sigovan, M., Knauer, H. A., Tseng, E. E., Saloner, D., & Hope, M. D. (2014) · Investigative Radiology · doi:10.1097/rli.0000000000000064 · Cited by 57
Biomechanical modeling of transcatheter aortic valve replacement in a stenotic bicuspid aortic valve: deployments and paravalvular leakage
Lavon, K., Marom, G., Bianchi, M., Halevi, R., Hamdan, A., Morany, A., Raanani, E., Bluestein, D., & Haj-Ali, R. M. (2019) · Medical & Biological Engineering & Computing · doi:10.1007/s11517-019-02012-y · Cited by 57
Aortic Regurgitation
Flint, N., Wunderlich, N. C., Shmueli, H., Ben‐Zekry, S., Siegel, R. J., & Beigel, R. (2019) · Current Cardiology Reports · doi:10.1007/s11886-019-1144-6 · Cited by 60
Deregulation of Notch1 pathway and circulating endothelial progenitor cell (EPC) number in patients with bicuspid aortic valve with and without ascending aorta aneurysm
Balistreri, C. R., Crapanzano, F., Schirone, L., Allegra, A., Pisano, C., Ruvolo, G., Forte, M., Greco, E., Cavarretta, E., Marullo, A. G. M., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-32170-2 · Cited by 56
Sex differences in bicuspid aortic valve disease
Kong, W. K. F., Bax, J. J., Michelena, H. I., & Delgado, V. (2020) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2020.06.004 · Cited by 56
NOTCH Signaling in Aortic Valve Development and Calcific Aortic Valve Disease
Wang, Y., Fang, Y., Lu, P., Wu, B., & Zhou, B. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.682298 · Cited by 56
Transcatheter aortic valve implantation with the Evolut platform for bicuspid aortic valve stenosis: the international, multicentre, prospective BIVOLUTX registry
Tchétché, D., Ziviello, F., Biase, C. D., Backer, O. D., Hovasse, T., Leroux, L., Petronio, A.-S., Saint‐Etienne, C., Teles, R. C., Modine, T., et al. (2023) · EuroIntervention · doi:10.4244/eij-d-23-00021 · Cited by 55
Pathogenesis of aortic wall complications in Marfan syndrome
Grewal, N., & Groot, A. C. G. (2018) · Cardiovascular Pathology · doi:10.1016/j.carpath.2018.01.005 · Cited by 55
Exercise recommendations in patients with valvular heart disease
Gati, S., Malhotra, A., & Sharma, S. (2018) · Heart · doi:10.1136/heartjnl-2018-313372 · Cited by 55
Innate immune cells in the pathophysiology of calcific aortic valve disease: lessons to be learned from atherosclerotic cardiovascular disease?
Broeders, W., Bekkering, S., Messaoudi, S. E., Joosten, L. A. B., van Royen, N., & Riksen, N. P. (2022) · Basic Research in Cardiology · doi:10.1007/s00395-022-00935-6 · Cited by 57
Genetic Basis of Familial Valvular Heart Disease
Padang, R., Bagnall, R. D., & Semsarian, C. (2012) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.112.962894 · Cited by 54
Cardiothoracic Magnetic Resonance Flow Imaging
Hope, M. D., Sedlic, T., & Dyverfeldt, P. (2013) · Journal of Thoracic Imaging · doi:10.1097/rti.0b013e31829192a1 · Cited by 53
Transcatheter Aortic Valve Implantation (TAVI) in Patients With Bicuspid Aortic Valve Stenosis – Systematic Review and Meta-Analysis
Phan, K. H., Wong, S., Phan, S., Ha, H., Qian, P. C., & Yan, T. D. (2015) · Heart Lung and Circulation · doi:10.1016/j.hlc.2014.12.163 · Cited by 54
Comparison of multislice computed tomography findings between bicuspid and tricuspid aortic valves before and after transcatheter aortic valve implantation
Watanabe, Y., Chevalier, B., Hayashida, K., Leong, T., Bouvier, E., Arai, T., Farge, A., Hovasse, T., Garot, P., Cormier, B., et al. (2015) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.25830 · Cited by 53
The roles of non-coding RNAs in vascular calcification and opportunities as therapeutic targets
Ryu, J., Ahn, Y., Kook, H. Y., & Kim, Y. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2020.107675 · Cited by 53
Thoracic aorta 3D hemodynamics in pediatric and young adult patients with bicuspid aortic valve
Allen, B. D., van Ooij, P., Barker, A. J., Carr, M. L., Gabbour, M., Schnell, S., Jarvis, K., Carr, J., Markl, M., Rigsby, C. K., et al. (2015) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.24847 · Cited by 52
The Significance of the Interleaflet Triangles in Determining the Morphology of Congenitally Abnormal Aortic Valves: Implications for Noninvasive Imaging and Surgical Management
Tretter, J. T., Spicer, D. E., Mori, S., Chikkabyrappa, S. M., Redington, A. N., & Anderson, R. H. (2016) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2016.08.017 · Cited by 52
Elucidation of the genetic causes of bicuspid aortic valve disease
Gehlen, J., Stundl, A., Debiec, R., Fontana, F., Krane, M., Sharipova, D., Nelson, C. P., Al-Kassou, B., Giel, A.-S., Sinning, J.-M., et al. (2023) · Cardiovascular Research · doi:10.1093/cvr/cvac099 · Cited by 51
Patient-specific assessment of hemodynamics by computational fluid dynamics in patients with bicuspid aortopathy
Kimura, N., Nakamura, M., Komiya, K., Nishi, S., Yamaguchi, A., Tanaka, O., Misawa, Y., Adachi, H., & Kawahito, K. (2017) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2016.12.033 · Cited by 51
Congenital Aortic Valve Stenosis
Singh, G. K. (2019) · Children · doi:10.3390/children6050069 · Cited by 57
Sutureless aortic valve replacement in patients who have bicuspid aortic valve
Nguyen, A., Fortin, W., Mazine, A., Bouchard, D., Carrier, M., El-Hamamsy, I., Lamarche, Y., & Demers, P. (2015) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2015.05.071 · Cited by 50
Myths and Realities Relating to Development of the Arterial Valves
Anderson, R. H., Mohun, T. J., Spicer, D. E., Bamforth, S. D., Brown, N. A., Chaudhry, B., & Henderson, D. J. (2014) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd1030177 · Cited by 50
Embryonic development of bicuspid aortic valves
Soto‐Navarrete, M. T., López-Unzu, M. Á., Durán, A. C., & Fernández, B. (2020) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2020.06.008 · Cited by 50
Characteristic morphologies of the bicuspid aortic valve in patients with genetic syndromes
Niaz, T., Poterucha, J. T., Olson, T. M., Johnson, J. N., Craviari, C., Nienaber, T., Palfreeman, J., Cetta, F., & Hagler, D. J. (2018) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2017.10.008 · Cited by 49
Interactions between inflammatory activation and endothelial dysfunction selectively modulate valve disease progression in patients with bicuspid aortic valve
Ali, O. A., Chapman, M., Nguyen, T. H. T., Chirkov, Y. Y., Heresztyn, T., Mundisugih, J., & Horowitz, J. D. (2014) · Heart · doi:10.1136/heartjnl-2014-305509 · Cited by 49
DNA methylome analysis reveals distinct epigenetic patterns of ascending aortic dissection and bicuspid aortic valve
Sun, P., Lai, H., Shen, Y., Breeze, C. E., Beck, S., Hong, T., Wang, C., & Teschendorff, A. E. (2017) · Cardiovascular Research · doi:10.1093/cvr/cvx050 · Cited by 51
Aortic Aneurysms
Lu, H. S., & Daugherty, A. (2017) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.117.309578 · Cited by 49
Bicuspid aortic valve behaviour in elite athletes
Boraíta, A., Morales‐Acuna, F. J., Breysse, M. M., Heras, M.-E., Canda, A., Fuentes, M.-E., Chacón, A., Díaz-González, L., Rabadán, M., Laca, B. P., et al. (2019) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jez001 · Cited by 48
Vascular Smooth Muscle Cells
Majesky, M. W. (2016) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.116.308261 · Cited by 48
The Brazilian Society of Cardiology and Brazilian Society of Exercise and Sports Medicine Updated Guidelines for Sports and Exercise Cardiology - 2019
Ghorayeb, N., Stein, R., Daher, D. J., da Silveira, A. D., Ritt, L. E. F., dos Santos, D. F. P., Sierra, A., Herdy, A. H., de Araújo, C. G. S., Colombo, C. S. S. D. S., et al. (2019) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.20190048 · Cited by 51
Aortic Stenosis: Changing Disease Concepts
Rashedi, N., & Otto, C. M. (2015) · Journal of Cardiovascular Ultrasound · doi:10.4250/jcu.2015.23.2.59 · Cited by 47
A Regulated Trial of Bicuspid Aortic Valve Repair Supported by Geometric Ring Annuloplasty
Mazzitelli, D., Pfeiffer, S., Rankin, J. S., Fischlein, T. J. M., Choi, Y., Wahlers, T., Nöbauer, C., Schreiber, C., & Lange, R. (2015) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2015.01.050 · Cited by 45
Surgical Thresholds for Bicuspid Aortic Valve Associated Aortopathy
Hardikar, A., & Marwick, T. H. (2013) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2013.10.005 · Cited by 45
Circulating Soluble Receptor for Advanced Glycation End Product Identifies Patients With Bicuspid Aortic Valve and Associated Aortopathies
Branchetti, E., Bavaria, J. E., Grau, J. B., Shaw, R. E., Poggio, P., Lai, E. K., Desai, N. D., Gorman, J. H., Gorman, R. C., & Ferrari, G. M. (2014) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.114.303784 · Cited by 44
Medical Treatment of Aortic Aneurysms in Marfan Syndrome and other Heritable Conditions
Jost, C. H. A., Greutmann, M., Connolly, H. M., Weber, R. W., Rohrbach, M., Oxenius, A., Kretschmar, O., Lüscher, T. F., & Mátyás, G. (2014) · Current Cardiology Reviews · doi:10.2174/1573403x1002140506124902 · Cited by 44
Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve Stenosis: A Practical Operative Overview
Tarantini, G., & Fabris, T. (2021) · Circulation Cardiovascular Interventions · doi:10.1161/circinterventions.120.009827 · Cited by 43
Impact of Balloon-Expandable TAVR Valve Deformation and Calcium Distribution on Outcomes in Bicuspid Aortic Valve
Nagasaka, T., Patel, V., Shechter, A., Suruga, K., Koren, O., Chakravarty, T., Cheng, W., Ishii, H., Jilaihawi, H., Nakamura, M., et al. (2024) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2024.07.018 · Cited by 44
Left ventricular response to pressure afterload in children: Aortic stenosis and coarctation
Jashari, H., Rydberg, A., Ibrahimi, P., Bajraktari, G., & Henein, M. Y. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.10.089 · Cited by 43
Genetic Dissection of Marfan Syndrome and Related Connective Tissue Disorders: An Update 2012
Hoffjan, S. (2012) · Molecular Syndromology · doi:10.1159/000339441 · Cited by 44
Architectural Trends in the Human Normal and Bicuspid Aortic Valve Leaflet and Its Relevance to Valve Disease
Aggarwal, A., Ferrari, G. M., Joyce, E., Daniels, M. J., Sainger, R., Gorman, J. H., Gorman, R. C., & Sacks, M. S. (2014) · Annals of Biomedical Engineering · doi:10.1007/s10439-014-0973-0 · Cited by 43
Incidence, Predictors, and Outcomes of Paravalvular Regurgitation After TAVR in Sievers Type 1 Bicuspid Aortic Valves
Zito, A., Buono, A., Scotti, A., Kim, W.-K., Fabris, T., Biase, C. D., Bellamoli, M., Montarello, N. J., Costa, G., Alfadhel, M., et al. (2024) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2024.05.002 · Cited by 42
Impact of Age and Gender on Cardiac Pathology in Children and Adolescents With Marfan Syndrome
Mueller, G. C., Stark, V. C., Steiner, K., Kodolitsch, Y. V., Rybczynski, M., Weil, J., & Mir, T. S. (2012) · Pediatric Cardiology · doi:10.1007/s00246-012-0593-0 · Cited by 42
Effects of clinico-pathological risk factors on in-vitro mechanical properties of human dilated ascending aorta
Ferrara, A., Totaro, P., Morganti, S., & Auricchio, F. (2017) · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials · doi:10.1016/j.jmbbm.2017.08.032 · Cited by 41
Aortic morphological variability in patients with bicuspid aortic valve and aortic coarctation
Sophocleous, F., Biffi, B., Milano, E. G., Bruse, J. L., Caputo, M., Rajakaruna, C., Schievano, S., Emanueli, C., Bucciarelli‐Ducci, C., & Biglino, G. (2018) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezy339 · Cited by 41
Early outcomes of transcatheter versus surgical aortic valve implantation in patients with bicuspid aortic valve stenosis
Majmundar, M. M., Kumar, A., Doshi, R. P., Shariff, M., Krishnaswamy, A., Reed, G. W., Brockett, J., Lahorra, J. L., Svensson, L. S., Puri, R., et al. (2022) · EuroIntervention · doi:10.4244/eij-d-21-00757 · Cited by 41
Smad2-Dependent Protease Nexin-1 Overexpression Differentiates Chronic Aneurysms From Acute Dissections of Human Ascending Aorta
Gomez, D. A., Kessler, K., Borges, L. D. F., Richard, B., Touat, Z., Ollivier, V., Mansilla, S., Bouton, M., Alkoder, S., Nataf, P., et al. (2013) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.113.301327 · Cited by 41
Comparison of Outcomes and Presentation in Men-Versus-Women With Bicuspid Aortic Valves Undergoing Aortic Valve Replacement
Andrei, A., Yadlapati, A., Malaisrie, S. C., Puthumana, J. J., Li, Z., Rigolin, V. H., Mendelson, M. A., Clennon, C., Kruse, J. T., Fedak, P. W. M., et al. (2015) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2015.04.017 · Cited by 40
Fate of remnant sinuses of Valsalva in patients with bicuspid and trileaflet valves undergoing aortic valve, ascending aorta, and aortic arch replacement
Milewski, R. K., Habertheuer, A., Bavaria, J. E., Siki, M. A., Szeto, W. Y., Krause, E. M., Korutla, V., Desai, N. D., & Vallabhajosyula, P. (2017) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2017.03.150 · Cited by 40
Recent Advances in Biomechanical Characterization of Thoracic Aortic Aneurysms
Cebull, H. L., Rayz, V. L., & Goergen, C. J. (2020) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2020.00075 · Cited by 40
Transcatheter and surgical aortic valve replacement in patients with bicuspid aortic valve
Husso, A., Airaksinen, J. K. E., Juvonen, T. S., Laine, M., Dahlbacka, S., Virtanen, M. P. O., Niemelä, M. J., Mäkikallio, T. H., Savontaus, M., Eskola, M. J., et al. (2020) · Clinical Research in Cardiology · doi:10.1007/s00392-020-01761-3 · Cited by 40
Short membranous septum length in bicuspid aortic valve stenosis increases the risk of conduction disturbances
Hamdan, A., Nassar, M., Schwammenthal, E., Perlman, G., Arow, Z., Lessick, J., Kerner, A., Barsheshet, A., Assa, H. V., Assali, A., et al. (2020) · Journal of cardiovascular computed tomography · doi:10.1016/j.jcct.2020.10.002 · Cited by 40
Potential role of an athlete-focused echocardiogram in sports eligibility
Palermi, S., Serio, A., Vecchiato, M., Sirico, F., Gambardella, F., Ricci, F., Iodice, F., Radmilovic, J., Russo, V., & D’Andrea, A. (2021) · World Journal of Cardiology · doi:10.4330/wjc.v13.i8.271 · Cited by 40
The aortic stenosis complex: aortic valve, atherosclerosis, aortopathy
Boudoulas, K. D., Wolfe, B., Ravi, Y., Lilly, S. M., Nagaraja, H. N., & Sai‐Sudhakar, C. (2015) · Journal of Cardiology · doi:10.1016/j.jjcc.2014.12.021 · Cited by 43
Comparative transcriptome profiling in human bicuspid aortic valve disease using RNA sequencing
Padang, R., Bagnall, R. D., Tsoutsman, T., Bannon, P. G., & Semsarian, C. (2015) · Physiological Genomics · doi:10.1152/physiolgenomics.00115.2014 · Cited by 39
Genetic and Developmental Contributors to Aortic Stenosis
Dutta, P., James, J. F., Kazik, H. B., & Lincoln, J. (2021) · Circulation Research · doi:10.1161/circresaha.120.317978 · Cited by 43
Cardiovascular Outcomes in Aortopathy
Holmes, K. W., Markwardt, S., Eagle, K. A., Devereux, R. B., Weinsaft, J. W., Asch, F. M., LeMaire, S. A., Maslen, C. L., Song, H. K., Milewicz, D. M., et al. (2022) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2022.03.367 · Cited by 40
Echocardiography Screening of Siblings of Children With Bicuspid Aortic Valve
Hales, A. R., & Mahle, W. T. (2014) · PEDIATRICS · doi:10.1542/peds.2013-3051 · Cited by 39
Whole Exome Sequencing for Familial Bicuspid Aortic Valve Identifies Putative Variants
Martin, L. J., Pilipenko, V. V., Kaufman, K. M., Cripe, L. H., Kottyan, L. C., Keddache, M. A., Dexheimer, P. J., Weirauch, M. T., & Benson, D. W. (2014) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.114.000526 · Cited by 39
Dilatation of the Remaining Aorta After Aortic Valve or Aortic Root Replacement in Patients With Bicuspid Aortic Valve: A 5-Year Follow-Up
Abdulkareem, N., Soppa, G. K. R., Jones, S., Valencia, O., Smelt, J., & Jahangiri, M. (2013) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2013.03.086 · Cited by 39
Cardiovascular diseases in Paralympic athletes
Pelliccia, A., Quattrini, F. M., Squeo, M. R., Caselli, S., Culasso, F., Link, M. S., Spataro, A., & Bernardi, M. (2016) · British Journal of Sports Medicine · doi:10.1136/bjsports-2015-095867 · Cited by 39
Transcatheter aortic valve implantation in bicuspid aortic valve stenosis
Perlman, G., Blanke, P., & Webb, J. G. (2016) · EuroIntervention · doi:10.4244/eijv12sya10 · Cited by 39
Prevalence of Symptomatic Congenital Heart Disease in Tibetan School Children
Zheng, J., Tian, H.-T., Zhu, Z., Li, B., Han, L., Jiang, S., Chen, Y., Li, D., He, J.-C., Zhao, Z., et al. (2013) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2013.07.028 · Cited by 39
Locally Different Endothelial Nitric Oxide Synthase Protein Levels in Ascending Aortic Aneurysms of Bicuspid and Tricuspid Aortic Valve
Mohamed, S. A., Radtke, A., Saraei, R., BULLERDIEK, J., Sorani, H., Nimzyk, R., Karluß, A., Sievers, H. H., & Belge, G. (2012) · Cardiology Research and Practice · doi:10.1155/2012/165957 · Cited by 39
Hereditary patterns of bicuspid aortic valve in a hundred families
Robledo-Carmona, J., Rodríguez–Bailón, I., Carrasco‐Chinchilla, F., Fernández, B., Jiménez-Navarro, M. F., Porras, C., Montiel-Trujillo, Á., García‐Pinilla, J. M., Such-Martínez, M., & de Teresa–Galván, E. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2013.04.180 · Cited by 41
Aneurysm Development in Patients With a Bicuspid Aortic Valve Is Not Associated With Transforming Growth Factor-β Activation
Paloschi, V., Gådin, J. R., Khan, S. A., Björck, H. M., Du, L., Maleki, S., Roy, J., Lindeman, J. H. N., Mohamed, S. A., Tsuda, T., et al. (2015) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.114.304996 · Cited by 38
Familial Aggregation of Aortic Valvular Stenosis
Martinsson, A., Li, X., Zöller, B., Andell, P., Andersson, C., Sundquist, K., & Smith, J. G. (2017) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.117.001742 · Cited by 39
Concepts of Bicuspid Aortic Valve Repair: A Review
Ram, D., Bouhout, I., Karliova, I., Schneider, U., El-Hamamsy, I., & Schäfers, H. (2019) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2019.09.019 · Cited by 38
Aortic stenosis and the haemostatic system
Trimaille, A., Hmadeh, S., Matsushita, K., Marchandot, B., Kauffenstein, G., & Morel, O. (2022) · Cardiovascular Research · doi:10.1093/cvr/cvac192 · Cited by 42
Pre- and Postoperative Imaging of the Aortic Root
Hanneman, K. A., Chan, F. P., Mitchell, R. S., Miller, D. C., & Fleischmann, D. (2016) · Radiographics · doi:10.1148/rg.2016150053 · Cited by 37
Comparing outcomes after transcatheter aortic valve replacement in patients with stenotic bicuspid and tricuspid aortic valve: A systematic review and meta‐analysis
Kanjanahattakij, N., Horn, B., Vutthikraivit, W., Biso, S. M. R., Ziccardi, M. R., Lu, M. L. R. Y., & Rattanawong, P. (2018) · Clinical Cardiology · doi:10.1002/clc.22992 · Cited by 37
Pressure drop mapping using 4D flow MRI in patients with bicuspid aortic valve disease: A novel marker of valvular obstruction
Hassanabad, A. F., Burns, F., Bristow, M., Lydell, C. P., Howarth, A. G., Heydari, B., Gao, X., Fedak, P. W. M., White, J. A., & García, J. (2019) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2019.11.011 · Cited by 37
Steady Flow Hemodynamic and Energy Loss Measurements in Normal and Simulated Calcified Tricuspid and Bicuspid Aortic Valves
Seaman, C., Akingba, A. G., & Sucosky, P. (2014) · Journal of Biomechanical Engineering · doi:10.1115/1.4026575 · Cited by 37
Transcatheter Heart Valves: A Biomaterials Perspective
Bui, H. T., Khair, N., Yeats, B., Gooden, S., James, S. P., & Dasi, L. P. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202100115 · Cited by 36
Frequency of Intracranial Aneurysms Determined by Magnetic Resonance Angiography in Children (Mean Age 16) Having Operative or Endovascular Treatment of Coarctation of the Aorta (Mean Age 3)
Donti, A., Spinardi, L., Brighenti, M., Faccioli, L., Leoni, C., Fabi, M., Trossello, M. P., Gargiulo, G., & Bonvicini, M. (2015) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2015.05.030 · Cited by 36
Aortic Valve Reconstruction in the Young Infants and Children
Baird, C. W., Myers, P. O., & del Nido, P. J. (2012) · Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery Annual · doi:10.1053/j.pcsu.2012.01.004 · Cited by 36
Prevalence and predictors of intracranial aneurysms in patients with bicuspid aortic valve
Egbe, A. C., Padang, R., Brown, R. D., Khan, A. R., Luis, S. A., Huston, J., Akintoye, E. O., & Connolly, H. M. (2017) · Heart · doi:10.1136/heartjnl-2016-311076 · Cited by 36
Fluid–Structure Interaction Models of Bicuspid Aortic Valves: The Effects of Nonfused Cusp Angles
Lavon, K., Halevi, R., Marom, G., Zekry, S. B., Hamdan, A., Schäfers, H., Raanani, E., & Haj-Ali, R. M. (2017) · Journal of Biomechanical Engineering · doi:10.1115/1.4038329 · Cited by 35
Bicuspid aortic valve-associated aortopathy: Where do we stand?
Meßner, B., & Bernhard, D. (2019) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2019.05.023 · Cited by 35
Hereditary Connective Tissue Diseases in Young Adult Stroke: A Comprehensive Synthesis
Vanakker, O. M., Hemelsoet, D., & Paepe, A. D. (2011) · Stroke Research and Treatment · doi:10.4061/2011/712903 · Cited by 37
Aortic valve repair update
Komiya, T. (2015) · General Thoracic and Cardiovascular Surgery · doi:10.1007/s11748-015-0523-1 · Cited by 34
Gender-related outcomes after open repair of descending thoracic and thoracoabdominal aortic aneurysms
Girardi, L. N., Leonard, J. R., Lau, C., Ohmes, L. B., Gambardella, I., Iannacone, E., Munjal, M., Schwann, A. N., & Gaudino, M. F. L. (2018) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2018.06.213 · Cited by 34
4D flow imaging of the thoracic aorta: is there an added clinical value?
Catapano, F., Pambianchi, G., Cundari, G., Rebelo, J., Cilia, F., Carbone, I., Catalano, C., Francone, M., & Galea, N. (2020) · Cardiovascular Diagnosis and Therapy · doi:10.21037/cdt-20-452 · Cited by 34

Authors: Siu, S. C., & Silversides, C. K.
Affiliations: Western University (CA)
University Health Network (CA)
Corresponding author: Siu, Samuel C.
ORCID: Siu, Samuel C.
Venue: Journal of the American College of Cardiology
Publisher: Elsevier BV
Published: 2010-06
Volume: 55
Issue: 25
Pages: 2789-2800
ISSN: 0735-1097 (ISSN-L)
DOI: 10.1016/j.jacc.2009.12.068
OpenAlex: W2121967184
Cited by: 1,028
References: 143
Citations by year: 2026: 37 · 2025: 62 · 2024: 59 · 2023: 85 · 2022: 68 · 2021: 100 · 2020: 71 · 2019: 61 · 2018: 63 · 2017: 79 · 2016: 69 · 2015: 67 · 2014: 64 · 2013: 49 · 2012: 57
FWCI: 7.88
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 1178 d)
Locations: Journal of the American College of Cardiology (publishedVersion)
PubMed (publishedVersion)
Scholarship@Western (Western University) (submittedVersion)
Funders: Heart and Stroke Foundation of Canada (NA 5927, NA 5662, T6085)
Canadian Institutes of Health Research (53030, 93722)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Aortic Disease and Treatment Approaches
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Valve Diseases and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
Keywords: bicuspid aortic valve, congenital heart disease, aortic root dilatation, aortic stenosis, aortic incompetence, infective endocarditis, aortic aneurysm, aortic dissection, aortic valve replacement, aortic root surgery, life expectancy, pathobiology, clinical course, surveillance (medicine), medical treatment, intervention timing
MeSH terms: Adult, Aortic Valve, Aortic Valve Insufficiency, Aortic Valve Stenosis, Cause of Death, Combined Modality Therapy, Female, Heart Defects, Congenital, Humans, Magnetic Resonance Imaging, Male, Mitral Valve, Prognosis, Severity of Illness Index, Survival Rate, Echocardiography, Transesophageal, Risk Assessment, Heart Valve Prosthesis Implantation, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Bicuspid Aortic Valve Disease

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks