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Bicuspid Aortic Valve Disease
Open accessAbstract
Bicuspid aortic valve (BAV) disease is the most common congenital cardiac defect. While the BAV can be found in isolation, it is often associated with other congenital cardiac lesions. The most frequent associated finding is dilation of the proximal ascending aorta secondary to abnormalities of the aortic media. Changes in the aortic media are present independent of whether the valve is functionally normal, stenotic, or incompetent. Although symptoms often manifest in adulthood, there is a wide spectrum of presentations ranging from severe disease detected in utero to asymptomatic disease in old age. Complications can include aortic valve stenosis or incompetence, endocarditis, aortic aneurysm formation, and aortic dissection. Despite the potential complications, 2 large contemporary series have demonstrated that life expectancy in adults with BAV disease is not shortened when compared with the general population. Because BAV is a disease of both the valve and the aorta, surgical decision making is more complicated, and many undergoing aortic valve replacement will also need aortic root surgery. With or without surgery, patients with BAV require continued surveillance. Recent studies have improved our understanding of the genetics, the pathobiology, and the clinical course of the disease, but questions are still unanswered. In the future, medical treatment strategies and timing of interventions will likely be refined. This review summarizes our current understanding of the pathology, genetics, and clinical aspects of BAV disease with a focus on BAV disease in adulthood.
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“Male sex is recognized as a risk factor for CAVS, partly due to the higher prevalence of bicuspid aortic valve (BAV) in men, with a male-to-female ratio of 3:1 5 .”
From Sex-specific gene expression signatures of calcific aortic valve stenosis in a large collection of human tissues (2026) · cites this paper as [5]
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ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.176857 · Cited by 8,487
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.05.007 · Cited by 2,245
Warnes, C. A., Williams, R. G., Bashore, T. M., CHILD, J. S., Connolly, H. M., Dearani, J. A., del Nido, P. J., Fasules, J. W., Graham, T. P., Hijazi, Z. M., et al. (2008) · Circulation · doi:10.1161/circulationaha.108.190811 · Cited by 2,068
Clinical Factors Associated With Calcific Aortic Valve Disease
Stewart, B. F., Siscovick, D., Lind, B. K., Gardin, J. M., Gottdiener, J. S., Smith, V. E., Kitzman, D. W., & Otto, C. M. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(96)00563-3 · Cited by 2,029
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.05.021 · Cited by 1,702
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease
Warnes, C. A., Williams, R. G., Bashore, T. M., CHILD, J. S., Connolly, H. M., Dearani, J. A., del Nido, P. J., Fasules, J. W., Graham, T. P., Hijazi, Z. M., et al. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.10.001 · Cited by 1,553
Mutations in NOTCH1 cause aortic valve disease
Garg, V., Muth, A. N., Ransom, J. F., Schluterman, M. K., Barnes, R., King, I. N., Grossfeld, P. D., & Srivastava, D. (2005) · Nature · doi:10.1038/nature03940 · Cited by 1,509
Suggested standards for reporting on arterial aneurysms
Johnston, K. W., Rutherford, R. B., Tilson, M. D., Shah, D. M., Hollier, L. H., & Stanley, J. C. (1991) · Journal of Vascular Surgery · doi:10.1067/mva.1991.26737 · Cited by 1,369
Predictors of Outcome in Severe, Asymptomatic Aortic Stenosis
Rosenhek, R., Binder, T. M., Porenta, G., Lang, I. M., Christ, G., SCHEMPER, M., Maurer, G., & Baumgartner, H. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008313430903 · Cited by 1,332
A classification system for the bicuspid aortic valve from 304 surgical specimens
Sievers, H.-H., & Schmidtke, C. (2007) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2007.01.039 · Cited by 1,222
Flagged first, then by citations
3 of the 143 references couldn’t be matched to a known paper.
Research works printed but not linked: 4
- Osler, 1886, The bicuspid condition of the aortic valve, Trans Assoc Am Physicians, 2, 185
- Nadas, 1977, Report from the Joint Study on the Natural History of Congenital Heart Defects, Circulation, 56, I36
- Bonow, 2006, J Am Coll Cardiol, 48, e1, 10.1016/j.jacc.2006.05.021 · DOI
- Warnes, 2008, J Am Coll Cardiol, 52, e1, 10.1016/j.jacc.2008.10.002 · DOI
Cited by
Sorted by citations
Items 301–400 of 999
Zheng, R., Zhu, P., Gu, J., Ni, B., Sun, H., He, K., Bian, J., Shao, Y., & Du, J. (2021) · Experimental Cell Research · doi:10.1016/j.yexcr.2021.112972 · Cited by 18
Managing aortic aneurysms and dissections during pregnancy
Mosquera, L. M., & Backer, J. F. A. D. (2015) · Expert Review of Cardiovascular Therapy · doi:10.1586/14779072.2015.1042862 · Cited by 17
Bicuspid aortic valve disease: systematic review and meta-analysis of surgical aortic valve repair
Salcher‐Konrad, M., Naci, H., Pender, S., Kühne, T., & Kelm, M. (2016) · Open Heart · doi:10.1136/openhrt-2016-000502 · Cited by 17
Imaging diagnosis of aortic stenosis
Mittal, T. K., & Marcus, N. (2020) · Clinical Radiology · doi:10.1016/j.crad.2020.04.008 · Cited by 17
CircRNA/lncRNA–miRNA–mRNA network and gene landscape in calcific aortic valve disease
Zheng, Y., Wen, S., Jiang, S., He, S., Qiao, W., Liu, Y., Yang, W., Zhou, J., Wang, B., Li, D., et al. (2023) · BMC Genomics · doi:10.1186/s12864-023-09441-y · Cited by 17
Khorramirouz, R., Sabetkish, S., Akbarzadeh, A., Muhammadnejad, A., Heidari, R., & Kajbafzadeh, A. M. (2014) · Advances in Medical Sciences · doi:10.1016/j.advms.2014.08.004 · Cited by 17
Aortic dimensions in patients with bicuspid and tricuspid aortic valves
Jackson, V., Olsson, C., Eriksson, P. O., & Franco‐Cereceda, A. (2012) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2012.07.039 · Cited by 17
The genetic component of bicuspid aortic valve and aortic dilation. An exome-wide association study
Gago‐Díaz, M., Brión, M., Gallego, P., Calvo, F., Robledo-Carmona, J., Saura, D., Sánchez, V., Bermejo, J., Sevilla, T., Newton‐Cheh, C., et al. (2016) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2016.11.012 · Cited by 16
Bianca, I., Geraci, G., Gulizia, M. M., Assenza, G. E., Barone, C., Campisi, M., Alaimo, A., Adorisio, R., Comoglio, F. M., Favilli, S., et al. (2017) · European Heart Journal Supplements · doi:10.1093/eurheartj/sux032 · Cited by 17
The many faces of bicuspid aortic valve disease
Cedars, A. M., & Braverman, A. C. (2012) · Progress in Pediatric Cardiology · doi:10.1016/j.ppedcard.2012.08.006 · Cited by 17
Csáky‐Szunyogh, M., Vereczkey, A., Kósa, Z., Gerencsér, B. S., & Czeizel, A. E. (2013) · Pediatric Cardiology · doi:10.1007/s00246-013-0749-6 · Cited by 18
Mai, Z., Guan, L., & Mu, Y. (2021) · Clinical Cardiology · doi:10.1002/clc.23736 · Cited by 16
Odelin, G., Faucherre, A., Marchese, D., Pinard, A., Jaouadi, H., Scouarnec, S. L., Deleuze, J., Génin, E., Lindenbaum, P., Redon, R., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-37110-x · Cited by 15
Dilatación aórtica en válvula aórtica bicúspide
Carro, A., Teixidó‐Turà, G., & Evangelista, A. (2012) · Revista Española de Cardiología · doi:10.1016/j.recesp.2012.04.025 · Cited by 16
Blackman, D. J., Gils, L. V., Bleiziffer, S., Gerckens, U. J., Petronio, A. S., Abdel‐Wahab, M., Werner, N., Khogali, S., Wenaweser, P., Wöhrle, J., et al. (2019) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.28120 · Cited by 16
Low risk TAVR: Long- term considerations and appropriate patient selection
Price, J., Bob‐Manuel, T., Aymond, J. D., Amoran, O., Almusawi, H., Kelly, J. M., Okor, I., Okoro, K. U., Ramee, S. R., & Soto, J. T. (2020) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2020.04.002 · Cited by 16
Gauer, S., Balint, B., Kollmann, C., Federspiel, J. M., Henn, D., Bandner‐Risch, D., Schmied, W., & Schäfers, H. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.120.016471 · Cited by 16
Patients with Bicuspid Aortopathy and Aortic Dilatation
Nappi, F., Giacinto, O., Lusini, M., Garo, M. L., Caponio, C., Nenna, A., Nappi, P., Rousseau, J., Spadaccio, C., & Chello, M. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11206002 · Cited by 16
Factors Determining Aortic Valve Dysfunction in Korean Subjects With a Bicuspid Aortic Valve
Lee, S. Y., Shim, C. Y., Kim, D., Cho, I., Hong, G., Ha, J., & Chung, N. (2017) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2017.03.038 · Cited by 16
Long-Term Outcomes of BAV-0 Patients Compared With BAV-1 and TAV Patients After TAVR
Li, W., Jia, Y., Li, H., Kobari, Y., Li, J., Feng, Y., Peng, Y., Wei, J., Zhao, Z., Xiong, T., et al. (2025) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2025.05.045 · Cited by 15
Role of Echocardiography Before Transcatheter Aortic Valve Implantation (TAVI)
Badiani, S., Bhattacharyya, S., & Lloyd, G. (2016) · Current Cardiology Reports · doi:10.1007/s11886-016-0715-z · Cited by 15
Cave, D. G. W., Panayiotou, H., & Bissell, M. M. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.629227 · Cited by 15
Michel, J. M., Frangieh, A. H., Giacoppo, D., Alvarez‐Covarrubias, H. A., Pellegrini, C., Rheude, T. A., Deutsch, O., Mayr, N. P., Rumpf, P. M., Stähli, B. E., et al. (2021) · Clinical Research in Cardiology · doi:10.1007/s00392-021-01935-7 · Cited by 15
Franco, P., Sotelo, J. A., Guala, A., Dux‐Santoy, L., Evangelista, A., Rodríguez-Palomares, J. F., Mery, D., Rodrigo Salas, F., & Uribe, S. A. (2021) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2021.105147 · Cited by 15
Development of the Human Arterial Valves: Understanding Bicuspid Aortic Valve
Henderson, D. J., Eley, L., Turner, J. E., & Chaudhry, B. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.802930 · Cited by 15
Torres, F. S., Windram, J. D., Bradley, T. J., Wintersperger, B. J., Menezes, R. J., Crean, A. M., Colman, J. M., Silversides, C. K., & Wald, R. M. (2013) · International journal of cardiac imaging · doi:10.1007/s10554-013-0268-9 · Cited by 15
Self-citationHeart Failure Caused by Congenital Left-Sided Lesions
Krieger, E. V., & Fernandes, S. M. (2013) · Heart Failure Clinics · doi:10.1016/j.hfc.2013.09.015 · Cited by 15
Magni, P. (2019) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2019.03.004 · Cited by 15
Mozzini, C., Girelli, D., Cominacini, L., & Soresi, M. (2019) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2019.04.005 · Cited by 15
Kochman, J., Zbroński, K., Kołtowski, Ł., Parma, R., Ochala, A. J., Huczek, Z., Rymuza, B., Wilimski, R., Dąbrowski, M., Witkowski, A., et al. (2019) · Clinical Research in Cardiology · doi:10.1007/s00392-019-01541-8 · Cited by 15
Vaideeswar, P., & BUTANY, J. W. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-420219-1.00012-4 · Cited by 15
The role of the bicuspid aortic valve in sudden cardiac death–findings at cardiac autopsy
Chatrath, N., Westaby, J. D., Finocchiaro, G., Sharma, S., Tome, M., Papadakis, M., & Sheppard, M. N. (2023) · Cardiovascular Pathology · doi:10.1016/j.carpath.2023.107527 · Cited by 14
Sadeghpour, A., Maleki, M., Movassaghi, M., Rezvani, L., Noohi, F., Boudagh, S., Ghadrdoost, B., Bakhshandeh, H., Alizadehasl, A., Naderi, N., et al. (2019) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2019.100433 · Cited by 14
Flyer, J. N., Sleeper, L. A., Colan, S. D., Singh, M. N., & Lacro, R. V. (2020) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2020.12.050 · Cited by 15
A SOX17-PDGFB signaling axis regulates aortic root development
Lu, P., WANG, P. H., Wu, B., Wang, Y., Liu, Y., Cheng, W., Feng, X., Yuan, X., Atteya, M. M., Ferro, H., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-31815-1 · Cited by 15
Clinical implications of the biomechanics of bicuspid aortic valve and bicuspid aortopathy
Hassanabad, A. F., King, M. A., Martino, E. S. D., Fedak, P. W. M., & García, J. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.922353 · Cited by 15
Aortic Dilatation in Bicuspid Aortic Valve Disease
Carro, A., Teixidó‐Turà, G., & Evangelista, A. (2012) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2012.04.018 · Cited by 14
Molecular mechanisms of inherited thoracic aortic disease – from gene variant to surgical aneurysm
Robertson, E., Dilworth, C., Lu, Y., Hambly, B. D., & Jeremy, R. (2014) · Biophysical Reviews · doi:10.1007/s12551-014-0147-1 · Cited by 14
Liu, S., Shi, Y., Liu, R., Tong, M., Luo, X., & Xu, J.-P. (2016) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2016.06.005 · Cited by 14
Miśkowiec, D. Ł., Lipiec, P., Szymczyk, E., Wejner‐Mik, P., Michalski, B. W., Kupczyńska, K., Wierzbowska-Drabik, K. A., & Kasprzak, J. D. (2018) · Echocardiography · doi:10.1111/echo.13818 · Cited by 14
Predictors of Aortic Valve Repair Failure
Yanagawa, B., Mazine, A., & El-Hamamsy, I. (2019) · Innovations Technology and Techniques in Cardiothoracic and Vascular Surgery · doi:10.1177/1556984519845905 · Cited by 14
van der Linde, D., Andrinopoulou, E.-R., Oechslin, E. N., Budts, W., van Dijk, A. P. J., Pieper, P. G., Wajon, E. M. C. J., Post, M. C., Witsenburg, M., Silversides, C. K., et al. (2012) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.10.027 · Cited by 14
Self-citationSex Differences in Aortic Valve Calcification
Shames, S., & Gillam, L. D. (2013) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.112.983288 · Cited by 14
Deutsch, O., Vitanova, K., Ruge, H., Erlebach, M., Krane, M., & Lange, R. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1252163 · Cited by 13
High-Gradient Aortic Stenosis With Valve Area >1.0 cm2
Ito, S., Oh, J. K., Michelena, H. I., Egbe, A. C., Connolly, H. M., Pellikka, P. A., Nkomo, V. T., Lewis, B. R., & Miranda, W. R. (2024) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2024.07.025 · Cited by 13
Yamanaka, F., Shishido, K., Moriyama, N., Ochiai, T., Miyashita, H., Yokoyama, H., Sugiyama, Y., Yashima, F., Ohno, Y., Nishina, H., et al. (2025) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2024.10.002 · Cited by 13
Perioperative transesophageal echocardiography for aortic dissection
Tan, C., & Fraser, A. G. (2014) · Canadian Journal of Anesthesia/Journal canadien d anesthésie · doi:10.1007/s12630-014-0113-1 · Cited by 13
Understanding and treating aortopathy in bicuspid aortic valve
Broberg, C. S., & Therrien, J. (2014) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2014.12.006 · Cited by 13
Yeats, B. B., Yadav, P., Dasi, L. P., & Thourani, V. H. (2022) · Current Cardiology Reports · doi:10.1007/s11886-021-01617-w · Cited by 13
Li, J., Yan, W., Wang, W., Wang, S., & Wei, L. (2022) · Journal of Biomechanical Engineering · doi:10.1115/1.4054332 · Cited by 13
Sex Differences in Cardiovascular Physiology and Pathophysiology
Regitz‐Zagrosek, V., Ventura‐Clapier, R., den Ruijter, H. M., Garnier, A., Barcena, M. L., Eikendal, A. L. M., & Hartman, R. J. G. (2019) · Elsevier eBooks · doi:10.1016/c2014-0-02648-2 · Cited by 13
Rueda-Martínez, C., Lamas, O., Mataró, M. J., Robledo-Carmona, J., Sánchez-Espín, G., Jiménez-Navarro, M. F., Such-Martínez, M., & Fernández, B. (2014) · PLoS ONE · doi:10.1371/journal.pone.0097449 · Cited by 13
Mei, S., Júnior, F. S. N. D. S., Kuan, M. Y. S., Green, N. C., & Espino, D. M. (2016) · Perfusion · doi:10.1177/0267659116656775 · Cited by 13
Nakamura, K., Passeri, J. J., & Inglessis‐Azuaje, I. (2016) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.26705 · Cited by 13
Alajbegovic, A., Holmberg, J., & Albinsson, S. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00569 · Cited by 13
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Forte, A., Balistreri, C. R., FEO, M. D., Corte, A. D., Hellstrand, P., Persson, L., & Nilsson, B. (2019) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2019.02.014 · Cited by 13
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Lee, A., Wei, S., & Schwertani, A. G. (2019) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2019.05.018 · Cited by 14
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Improta, R., Pietro, G. D., Kola, N., Birtolo, L. I., Colantonio, R., Bruno, E., Tocci, M., Giansante, A., Sannino, M., Zullino, V., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12237371 · Cited by 12
Schreurs, B. A., Hopman, M. T. E., Bakker, C. M., Duijnhouwer, A. L., van Royen, N., Thompson, P. D., van Kimmenade, R. R. J., & Eijsvogels, T. M. H. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.031850 · Cited by 12
Yu, Q., Fu, Q., Xia, Y., & Wu, Y. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1370244 · Cited by 11
Meng, Z., Zhang, H., Cai, Y., Gao, Y., Liang, C., Wang, J., Chen, X., Guo, L., & Wang, S. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1407215 · Cited by 12
Vascular manifestations of syndromic aortopathies: role of current and emerging imaging techniques
Westerland, O., Frigiola, A., Robert, L., Shaw, A. C., Blakeway, L., Katsanos, K. H., Kiesewetter, C., Chung, N. A. Y., & Karunanithy, N. (2015) · Clinical Radiology · doi:10.1016/j.crad.2015.08.008 · Cited by 12
Clinical Outcomes of Adults With Bicuspid Aortic Valve
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Perrin, N., Ibrahim, R., Dürrleman, N., Basmadjian, A., Leroux, L., Demers, P., Modine, T., & Ali, W. B. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.798949 · Cited by 12
Yeats, B. B., Yadav, P., Dasi, L. P., & Thourani, V. H. (2022) · Annals of Cardiothoracic Surgery · doi:10.21037/acs-2022-bav-20 · Cited by 12
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Ren, X., Zhang, M., Liu, K., Hou, Z., Gao, Y., Yin, W., Wang, Z., Li, Z., & Lü, B. (2015) · International journal of cardiac imaging · doi:10.1007/s10554-015-0783-y · Cited by 12
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Thudt, M., Papadopoulos, N., Monsefi, N., Miskovic, A., Karimian‐Tabrizi, A., Zierer, A. F., & Moritz, A. (2016) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2016.08.082 · Cited by 12
Kuan, M. Y. S., & Espino, D. M. (2014) · Computer Methods in Biomechanics & Biomedical Engineering · doi:10.1080/10255842.2014.900663 · Cited by 12
Karataş, Z., Baysal, T., Şap, F., Altın, H., & Çiçekler, H. (2013) · The Anatolian Journal of Cardiology · doi:10.5152/akd.2013.102 · Cited by 12
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Bicuspid Aortic Valve and Aortopathy: See the First, Then Look at the Second
Freeman, R. V., & Otto, C. M. (2013) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2013.01.001 · Cited by 12
Houessou, U., Zamani, P., Manikpurage, H. D., Li, Z., Gaudreault, N., Dahmene, M., Dagenais, F., Couture, C., Clavel, M.-A., Pibarot, P., et al. (2025) · JACC: Basic to Translational Science · doi:10.1016/j.jacbts.2025.01.018 · Cited by 11
Jabagi, H., Levine, D., Gharibeh, L., Camillo, C., Castillero, E., Ferrari, G. M., Takayama, H., & Grau, J. B. (2023) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2406178 · Cited by 11
Giacoppo, D., Alvarez‐Covarrubias, H. A., Xhepa, E., Matsuda, Y., Cangemi, S., Michel, J., Sannino, A., Ziegelmueller, J. A., Criscione, E., Fukutomi, M., et al. (2025) · Circulation · doi:10.1161/circulationaha.124.069323 · Cited by 11
Interventional cardiology in adults with congenital heart disease
Singh, H. S., Horlick, E. M., Osten, M., & Benson, L. N. (2013) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2013.127 · Cited by 11
Différences entre les sexes dans les cardiopathies congénitales
Aubry, P., & Demian, H. (2016) · Annales de Cardiologie et d Angéiologie · doi:10.1016/j.ancard.2016.10.006 · Cited by 11
Excess Provisional Extracellular Matrix: A Common Factor in Bicuspid Aortic Valve Formation
Kern, C. B. (2021) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd8080092 · Cited by 11
Guo, Y., Zhou, D., Dang, M., He, Y., Zhang, S., Fang, J., Wu, S., Huang, Q., Chen, L., Yuan, Y., et al. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.757190 · Cited by 11
Johnson, E., Scott, M., Jarvis, K., Allen, B. D., Carr, J., Malaisrie, S. C., McCarthy, P. M., Mehta, C. K., Fedak, P. W. M., Barker, A. J., et al. (2022) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.28266 · Cited by 11
Queen, R. A., Crosier, M., Eley, L., Kerwin, J. M., Turner, J. E., Yu, J., Alqahtani, A., Dhanaseelan, T., Overman, L. M., Soetjoadi, H., et al. (2023) · PLoS Genetics · doi:10.1371/journal.pgen.1010777 · Cited by 13
Complete Atrioventricular Block due to Infective Endocarditis of Bicuspid Aortic Valve
Park, M. Y., Jeon, H., Shim, B.-J., Kim, H., Lee, H. Y., Kang, J.-H., Kim, J.-J., Koh, Y., Shin, W., & Lee, J.-M. (2011) · Journal of Cardiovascular Ultrasound · doi:10.4250/jcu.2011.19.3.140 · Cited by 11
Overview of Sudden Cardiac Death in Young Athletes
Sheikh, N., & Sharma, S. (2011) · The Physician and Sportsmedicine · doi:10.3810/psm.2011.11.1936 · Cited by 11
Exercise in Valvular Heart Disease: Risks and Benefits
Parker, M. W., & Thompson, P. D. (2011) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2011.02.010 · Cited by 11
Evaluation of Cardiovascular Changes in Children with BAVs
Onan, S. H., Baykan, A., Sezer, S., Narin, F., Mavili, E., Baykan, Z., Uzum, K., & Narın, N. (2015) · Pediatric Cardiology · doi:10.1007/s00246-015-1302-6 · Cited by 11
Guglielmetti, L. C., Nazif, T. M., Sorabella, R. A., Akkoc, D., Kantor, A., Gómez, A., Wang, C. K., Takayama, H., Dizon, J. M., Borger, M. A., et al. (2016) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezw044 · Cited by 11
Maleki, S., Björck, H. M., Paloschi, V., Kjellqvist, S., Folkersen, L., Jackson, V., Franco‐Cereceda, A., & Eriksson, P. O. (2013) · Aorta · doi:10.12945/j.aorta.2013.12.011 · Cited by 11
Fibrillin 2 is upregulated in the ascending aorta of patients with bicuspid aortic valve
Rueda-Martínez, C., Lamas, O., Mataró, M. J., Robledo-Carmona, J., Sánchez-Espín, G., Moreno‐Santos, I., Carrasco‐Chinchilla, F., Gallego, P., Such-Martínez, M., de Teresa, E., et al. (2016) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezw277 · Cited by 11
Ward, R. M., Marsh, J. M., Gossett, J. M., Rettiganti, M. R., & Collins, R. T. (2017) · Pediatric Cardiology · doi:10.1007/s00246-017-1781-8 · Cited by 11
Choi, B. H., Ko, S. M., Shin, J. K., Chee, H. K., Kim, J. S., & Kim, J. (2018) · Acta Radiologica · doi:10.1177/0284185118787359 · Cited by 11
Outcomes of transcatheter aortic valve replacement in bicuspid aortic valve stenosis
Bob‐Manuel, T., Heckle, M., Ifedili, I., Wang, J., & Ibebuogu, U. N. (2019) · Annals of Translational Medicine · doi:10.21037/atm.2019.02.04 · Cited by 11
Pisano, C., D’Amico, F., Balistreri, C. R., Vacirca, S. R., Nardi, P., Altieri, C., Scioli, M. G., Bertoldo, F., Santo, L., Bellisario, D., et al. (2020) · Journal of Thoracic Disease · doi:10.21037/jtd.2020.03.122 · Cited by 11
Patent foramen ovale—When to close and how?
Maloku, A., Hamadanchi, A., Franz, M., Dannberg, G., Günther, A., Klingner, C. M., Schulze, P. C., & Möbius‐Winkler, S. (2021) · Herz · doi:10.1007/s00059-021-05061-y · Cited by 11
López‐Sainz, Á., Dentamaro, I., Galián-Gay, L., Calvo, F., Alegret, J. M., Sánchez, V., Citro, R., Moreo, A. M., Chirillo, F., Colonna, P., et al. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10225264 · Cited by 11
Zhang, H., Liu, D., Zhu, S., Wang, F., Sun, X., Yang, S., & Wang, C. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.759035 · Cited by 11
Pathophysiological Implications of Different Bicuspid Aortic Valve Configurations
Kari, F. A., Beyersdorf, F., & Siepe, M. (2012) · Cardiology Research and Practice · doi:10.1155/2012/735829 · Cited by 11
Comparative Transcriptome Analysis Reveals Substantial Tissue Specificity in Human Aortic Valve
Wang, J., Wāng, Y., Gu, W., Ni, B., Sun, H., Yu, T., Gu, W., Chen, L., & Shao, Y. (2016) · Evolutionary Bioinformatics · doi:10.4137/ebo.s37594 · Cited by 13
Metadata
- Authors
- Siu, S. C., & Silversides, C. K.
- Affiliations
- Western University (CA)
- University Health Network (CA)
- Corresponding author
- Siu, Samuel C.
- ORCID
- Siu, Samuel C.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2010-06
- Volume
- 55
- Issue
- 25
- Pages
- 2789-2800
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2121967184
- Cited by
- 1,028
- References
- 143
- Citations by year
- 2026: 37 · 2025: 62 · 2024: 59 · 2023: 85 · 2022: 68 · 2021: 100 · 2020: 71 · 2019: 61 · 2018: 63 · 2017: 79 · 2016: 69 · 2015: 67 · 2014: 64 · 2013: 49 · 2012: 57
- FWCI
- 7.88
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Scholarship@Western (Western University) (submittedVersion)
- Funders
- Heart and Stroke Foundation of Canada (NA 5927, NA 5662, T6085)
- Canadian Institutes of Health Research (53030, 93722)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Aortic Disease and Treatment Approaches
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Valve Diseases and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
- Keywords
- bicuspid aortic valve, congenital heart disease, aortic root dilatation, aortic stenosis, aortic incompetence, infective endocarditis, aortic aneurysm, aortic dissection, aortic valve replacement, aortic root surgery, life expectancy, pathobiology, clinical course, surveillance (medicine), medical treatment, intervention timing
- MeSH terms
- Adult, Aortic Valve, Aortic Valve Insufficiency, Aortic Valve Stenosis, Cause of Death, Combined Modality Therapy, Female, Heart Defects, Congenital, Humans, Magnetic Resonance Imaging, Male, Mitral Valve, Prognosis, Severity of Illness Index, Survival Rate, Echocardiography, Transesophageal, Risk Assessment, Heart Valve Prosthesis Implantation, Young Adult
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