Cited by 217Cardiovascular Health and Risk FactorsNutritional Studies and DietHealth Promotion and Cardiovascular Prevention

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Low-Risk Diet and Lifestyle Habits in the Primary Prevention of Myocardial Infarction in Men

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Åkesson, Agneta, Larsson, Susanna C., Discacciati, Andrea, Wolk, Alicja·2014·Journal of the American College of Cardiology

DOI 10.1016/j.jacc.2014.06.1190

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Abstract

Background Adherence to a combination of healthy dietary and lifestyle practices may have an impressive impact on the primary prevention of myocardial infarction (MI).Objectives The aim of this study was to examine the benefit of combined low-risk diet and healthy lifestyle practices on the incidence of MI in men.Methods The population-based, prospective cohort of Swedish men comprised 45- to 79-year-old men who completed a detailed questionnaire on diet and lifestyle at baseline in 1997. In total, 20,721 men with no history of cancer, cardiovascular disease, diabetes, hypertension, or high cholesterol levels were followed through 2009. Low-risk behavior included 5 factors: a healthy diet (top quintile of Recommended Food Score), moderate alcohol consumption (10 to 30 g/day), no smoking, being physically active (walking/bicycling ≥40 min/day and exercising ≥1 h/week), and having no abdominal adiposity (waist circumference <95 cm).Results During 11 years of follow-up, we ascertained 1,361 incident cases of MI. The low-risk dietary choice together with moderate alcohol consumption was associated with a relative risk of 0.65 (95% confidence interval [CI]: 0.48 to 0.87) compared with men having 0 of 5 low-risk factors. Men having all 5 low-risk factors compared with those with 0 low-risk factors had a relative risk of 0.14 (95% CI: 0.04 to 0.43). This combination of healthy behaviors, present in 1% of the men, could prevent 79% (95% CI: 34% to 93%) of the MI events on the basis of the study population.Conclusions Almost 4 of 5 MIs in men may be preventable with a combined low-risk behavior.

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Authors: Åkesson, A., Larsson, S. C., Discacciati, A., & Wolk, A.
Affiliations: Karolinska Institutet (SE)
Corresponding author: Åkesson, Agneta
ORCID: Åkesson, Agneta
Larsson, Susanna C.
Wolk, Alicja
Venue: Journal of the American College of Cardiology
Publisher: Elsevier BV
Published: 2014-09
Volume: 64
Issue: 13
Pages: 1299-1306
ISSN: 0735-1097 (ISSN-L)
DOI: 10.1016/j.jacc.2014.06.1190
OpenAlex: W180905446
Cited by: 216
References: 38
Citations by year: 2026: 5 · 2025: 10 · 2024: 10 · 2023: 9 · 2022: 5 · 2021: 25 · 2020: 19 · 2019: 20 · 2018: 20 · 2017: 31 · 2016: 25 · 2015: 31 · 2014: 6
FWCI: 21.40
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 394 d)
Locations: Journal of the American College of Cardiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
Keywords: myocardial infarction, primary prevention, healthy lifestyle, moderate drinking, physical activity, smoking, abdominal fat, waist circumference, men, cardiovascular risk factors, preventability
MeSH terms: Adipose Tissue, Aged, Diet, Feeding Behavior, Humans, Life Style, Male, Middle Aged, Myocardial Infarction, Primary Prevention, Prospective Studies, Surveys and Questionnaires, Risk, Sweden

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Low-Risk Diet and Lifestyle Habits in the Primary Prevention of Myocardial Infarction in Men

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