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Psychopharmacology and Cardiovascular Disease
Open accessAbstract
This review discusses common mental health disorders and their associations with cardiovascular disease risks. Commonly found mental health disorders include depression, anxiety, and personality types. The link between depression and cardiovascular disease mortality has been established. Depression is also common in patients with heart failure. In addition to discussing psychological disorders, a review of psychotropic drugs is also included. Drugs are described for therapy for depression and anxiety, as well as associations with cardiovascular drug-drug interactions. Drug-drug interactions are more common and potentially dangerous in elderly patients, in whom the conditions often coexist. The most common drug-drug interactions involve the P450 system of enzymes.
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“Pharmacotherapy treatment for mental health disorders can present cardiovascular risk due to side effects of the drugs or interactions with other medications (Pina 2018).”
From Psychotherapeutic treatments for depression in older adults (2024) · cites this paper as Pina 2018
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“Pharmacological treatment of depression may be an option in patients with CVD, but the effects are small [1]. Moreover, such treatment poses a challenge as adding another medication to the existing complex medical treatment may be perceived as burdensome and might increase the risk of developing side effects [3].”
From An Internet-Based Cognitive Behavioral Therapy Program Adapted to Patients With Cardiovascular Disease and Depression: Randomized Controlled Trial (2019) · cites this paper as [3]
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Metadata
- Authors
- Piña, I. L., Di Palo, K. E., & Ventura, H. O.
- Affiliations
- Albert Einstein College of Medicine (US)
- Corresponding author
- Piña, Ileana L.
- ORCID
- Piña, Ileana L.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2018-05
- Volume
- 71
- Issue
- 20
- Pages
- 2346-2359
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2803606348
- Cited by
- 126
- References
- 131
- Citations by year
- 2026: 9 · 2025: 14 · 2024: 20 · 2023: 20 · 2022: 23 · 2021: 13 · 2020: 11 · 2019: 11 · 2018: 5
- FWCI
- 1.87
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- psychopharmacology, cardiovascular disease, depression, anxiety, personality types, heart failure, cardiovascular mortality, psychotropic drugs, drug-drug interactions, elderly patients, cytochrome P450
- MeSH terms
- Mental Disorders, Cardiovascular Agents, Cardiovascular Diseases, Drug Interactions, Humans, Psychopharmacology, Psychotropic Drugs, Risk Factors
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