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Association of Clonal Hematopoiesis With Incident Heart Failure
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“Several studies have implicated CH as an independent risk factor for cardiovascular diseases, including myocardial infarction4,5, stroke6 and heart failure7–9, providing a potential explanation for the increased non-cancer mortality in individuals with CH.”
From Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis (2023) · cites this paper as [9]
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“Several studies have implicated activation of the NLRP3 inflammasome and increased IL-1β production as causal drivers of non-malignant disease observed in human CH with TET2 mutations and mouse models of CH with Tet2 mutations 78,97,99,103,105,113,129,188,189 .”
From Clonal haematopoiesis and dysregulation of the immune system (2023) · cites this paper as [99]
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Cites
Age-related clonal hematopoiesis associated with adverse outcomes
Jaiswal, S., Fontanillas, P., Flannick, J., Manning, A., Grauman, P. V., Mar, B. G., Lindsley, R. C., Mermel, C. H., Burtt, N., Chavez, A., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1408617 · Cited by 4,841
Self-citationClonal hematopoiesis and risk of atherosclerotic cardiovascular disease
Jaiswal, S., Natarajan, P., Silver, A. J., Gibson, C. J., Bick, A. G., Shvartz, E., McConkey, M., Gupta, N., Gabriel, S., Ardissino, D., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1701719 · Cited by 2,683
Self-citationClonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
Fuster, J. J., MacLauchlan, S., Zuriaga, M. A., Polackal, M. N., Ostriker, A. C., Chakraborty, R., Wu, C.-L., Sano, S., Muralidharan, S., Rius, C., et al. (2017) · Science · doi:10.1126/science.aag1381 · Cited by 1,536
Landscape of genetic lesions in 944 patients with myelodysplastic syndromes
Haferlach, T., Nagata, Y., Grossmann, V, Okuno, Y., Bacher, U., Nagae, G., Schnittger, S., Sanada, M., Kon, A., Alpermann, T., et al. (2014) · Leukemia · doi:10.1038/leu.2013.336 · Cited by 1,532
Clonal hematopoiesis in human aging and disease
Jaiswal, S., & Ebert, B. L. (2019) · Science · doi:10.1126/science.aan4673 · Cited by 1,156
Self-citationInherited causes of clonal haematopoiesis in 97,691 whole genomes
Bick, A. G., Weinstock, J. S., Nandakumar, S. K., Fulco, C. P., Bao, E. L., Zekavat, S. M., Szeto, M. D., Liao, X., Leventhal, M. J., Nasser, J., et al. (2020) · Nature · doi:10.1038/s41586-020-2819-2 · Cited by 733
Self-citationLibby (2019) · doi:10.1016/j.jacc.2019.06.007 · Cited by 247
Wang, Y., Sano, S., Yura, Y., Ke, Z., Sano, M., Oshima, K., Ogawa, H., Horitani, K., Min, K.-D., Miura-Yura, E., et al. (2020) · JCI Insight · doi:10.1172/jci.insight.135204 · Cited by 167
Research works printed but not linked: 29
- Li, 2020, Targeting age-related pathways in heart failure, Circ Res, 126, 533, 10.1161/CIRCRESAHA.119.315889 · DOI
- Huffman, 2013, Lifetime risk for heart failure among white and black Americans: cardiovascular lifetime risk pooling project, J Am Coll Cardiol, 61, 1510, 10.1016/j.jacc.2013.01.022 · DOI
- Stewart, 2010, Population impact of heart failure and the most common forms of cancer: a study of 1 162 309 hospital cases in Sweden (1988 to 2004), Circ Cardiovasc Qual Outcomes, 3, 573, 10.1161/CIRCOUTCOMES.110.957571 · DOI
- Ayachi, 2020, 60 years of clonal hematopoiesis research: from X-chromosome inactivation studies to the identification of driver mutations, Exp Hematol, 83, 2, 10.1016/j.exphem.2020.01.008 · DOI
- Steensma, 2015, Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes, Blood, 126, 9, 10.1182/blood-2015-03-631747 · DOI · Paper page
- Natarajan, 2018, Clonal hematopoiesis: somatic mutations in blood cells and atherosclerosis, Circ Genom Precis Med, 11, 10.1161/CIRCGEN.118.001926 · DOI · Paper page
- Ebert, 2018, Clonal hematopoiesis confers predisposition to both cardiovascular disease and cancer: a newly recognized link between two major killers, Ann Intern Med, 169, 116, 10.7326/M18-0737 · DOI
- Fuster, 2018, Somatic mutations and clonal hematopoiesis: unexpected potential new drivers of age-related cardiovascular disease, Circ Res, 122, 523, 10.1161/CIRCRESAHA.117.312115 · DOI · Paper page
- Honigberg, 2021, Premature menopause, clonal hematopoiesis, and coronary artery disease in postmenopausal women, Circulation, 143, 410, 10.1161/CIRCULATIONAHA.120.051775 · DOI · Paper page
- Bick, 2020, Genetic interleukin 6 signaling deficiency attenuates cardiovascular risk in clonal hematopoiesis, Circulation, 141, 124, 10.1161/CIRCULATIONAHA.119.044362 · DOI · Paper page
- Abplanalp, 2020, Association of clonal hematopoiesis of indeterminate potential with inflammatory gene expression in patients with severe degenerative aortic valve stenosis or chronic postischemic heart failure, JAMA Cardiol, 5, 1170, 10.1001/jamacardio.2020.2468 · DOI · Paper page
- Sano, 2018, CRISPR-mediated gene editing to assess the roles of tet2 and dnmt3a in clonal hematopoiesis and cardiovascular disease, Circ Res, 123, 335, 10.1161/CIRCRESAHA.118.313225 · DOI · Paper page
- Dorsheimer, 2019, Association of mutations contributing to clonal hematopoiesis with prognosis in chronic ischemic heart failure, JAMA Cardiol, 4, 25, 10.1001/jamacardio.2018.3965 · DOI · Paper page
- Patel, 2019, A new murine model of clonal hematopoiesis investigates JAK2 (V617F) in heart failure, J Am Coll Cardiol Basic Trans Science, 4, 698
- Sano, 2019, JAK2 (V617F) -mediated clonal hematopoiesis accelerates pathological remodeling in murine heart failure, J Am Coll Cardiol Basic Transl Sci, 4, 684
- Sano, 2018, Tet2-mediated clonal hematopoiesis accelerates heart failure through a mechanism involving the IL-1beta/NLRP3 inflammasome, J Am Coll Cardiol, 71, 875, 10.1016/j.jacc.2017.12.037 · DOI · Paper page
- Cibulskis, 2013, Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples, Nat Biotechnol, 31, 213, 10.1038/nbt.2514 · DOI
- Petersen, 2016, UK Biobank's cardiovascular magnetic resonance protocol, J Cardiovasc Magn Reson, 18, 8, 10.1186/s12968-016-0227-4 · DOI · Paper page
- Zekavat, 2021, Elevated blood pressure increases pneumonia risk: epidemiological association and Mendelian randomization in the UK Biobank, Med (N Y), 2, 137
- Zekavat, 2019, Genetic association of finger photoplethysmography-derived arterial stiffness index with blood pressure and coronary artery disease, Arterioscler Thromb Vasc Biol, 39, 1253, 10.1161/ATVBAHA.119.312626 · DOI
- Cremer, 2020, Multiple somatic mutations for clonal hematopoiesis are associated with increased mortality in patients with chronic heart failure, Circ Genom Precis Med, 13, 10.1161/CIRCGEN.120.003003 · DOI
- Gelsi-Boyer, 2012, Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases, J Hematol Oncol, 5, 12, 10.1186/1756-8722-5-12 · DOI
- Thol, 2011, Prognostic significance of ASXL1 mutations in patients with myelodysplastic syndromes, J Clin Oncol, 29, 2499, 10.1200/JCO.2010.33.4938 · DOI
- Swirski, 2018, Cardioimmunology: the immune system in cardiac homeostasis and disease, Nat Rev Immunol, 18, 733, 10.1038/s41577-018-0065-8 · DOI
- Schiattarella, 2020, Distinctive patterns of inflammation across the heart failure syndrome, Heart Fail Rev.
- Everett, 2019, Anti-inflammatory therapy with canakinumab for the prevention of hospitalization for heart failure, Circulation, 139, 1289, 10.1161/CIRCULATIONAHA.118.038010 · DOI · Paper page
- Trankle, 2018, Usefulness of canakinumab to improve exercise capacity in patients with long-term systolic heart failure and elevated C-reactive protein, Am J Cardiol, 122, 1366, 10.1016/j.amjcard.2018.07.002 · DOI
- Svensson, 2018, TET2-driven clonal hematopoiesis predicts enhanced response to canakinumab in the CANTOS trial: an exploratory analysis, Circulation, 138, A15111
- Djohan, 2018, Endothelial progenitor cells in heart failure: an authentic expectation for potential future use and a lack of universal definition, J Cardiovasc Transl Res, 11, 393, 10.1007/s12265-018-9810-4 · DOI
Cited by
Clonal haematopoiesis and dysregulation of the immune system
Belizaire, R., Wong, W. J., Robinette, M. L., & Ebert, B. L. (2023) · Nature Reviews Immunology · doi:10.1038/s41577-023-00843-3 · Cited by 161
Self-citationClonal hematopoiesis: Mutation-specific adaptation to environmental change
Florez, M. A., Tran, B. T., Wathan, T. K., DeGregori, J., Pietras, E. M., & King, K. Y. (2022) · Cell Stem Cell · doi:10.1016/j.stem.2022.05.006 · Cited by 129
Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis
Liu, W., Yalcinkaya, M., Maestre, I. F., Olszewska, M., Ampomah, P. B., Heimlich, J. B., Wang, R., Vela, P. S., Xiao, T., Bick, A. G., et al. (2023) · Nature Cardiovascular Research · doi:10.1038/s44161-023-00281-3 · Cited by 93
Self-citationRole of serum cytokines in the prediction of heart failure in patients with coronary artery disease
Hou, Q., Sun, Z., Zhao, L., Liu, Y., Zhang, J., Huang, J., Luo, Y., Xiao, Y., Hu, Z., & Shen, A. (2023) · ESC Heart Failure · doi:10.1002/ehf2.14491 · Cited by 5
Evans, M. A., Chavkin, N. W., Sano, S., Sun, H., Sardana, T., Ravi, R., Doviak, H., Wang, Y., Yura, Y., Polizio, A. H., et al. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1487867 · Cited by 4
Metadata
- Authors
- Yu, B., Roberts, M. B., Raffield, L. M., Zekavat, S. M., Nguyen, N. Q. H., Biggs, M. L., Brown, M. R., Griffin, G., Desai, P., Correa, A., Morrison, A. C., Shah, A. M., Niroula, A., Uddin, M. M., Honigberg, M. C., Ebert, B. L., Psaty, B. M., Whitsel, E. A., Manson, J. E., Kooperberg, C., Bick, A. G., Ballantyne, C. M., Reiner, A. P., Natarajan, P., & Eaton, C. B.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2021-07
- Volume
- 78
- Issue
- 1
- Pages
- 42-52
- ISSN
- 0735-1097
- PMC
- PMC8313294
- Cited by
- 231
- References
- 8
- Language
- en
- Update notices
- erratum (2021-08-17)
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