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The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Asthma exacerbations: Origin, effect, and prevention

Open access
Jackson, David J., Sykes, Annemarie, Mallia, Patrick, Johnston, Sebastian L.·2011·Journal of Allergy and Clinical Immunology

Abstract

Asthma is the most common chronic respiratory disease, affecting up to 10% of adults and 30% of children in the Western world. Despite advances in asthma management, acute exacerbations continue to occur and impose considerable morbidity on patients and constitute a major burden on health care resources. Respiratory tract viruses have emerged as the most frequent triggers for exacerbations in both children and adults; however, the mechanisms underlying these remain poorly understood. More recently, it has become increasingly clear that interactions might exist between viruses and other triggers, increasing the likelihood of an exacerbation. In this article we begin with an overview of the health, economic, and social burden that exacerbations of asthma carry with them. This is followed by a review of the pathogenesis of asthma exacerbations, highlighting the various triggers responsible and multiple interactions that exist between them. The final section first addresses what preventative measures are currently available for asthma exacerbations and subsequently examines which of the new treatments in development might lessen the burden of exacerbations in the future.

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Crossref · 10.1016/j.jaci.2011.10.024

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Metadata

Authors
Jackson, D. J., Sykes, A., Mallia, P., & Johnston, S. L.
Venue
Journal of Allergy and Clinical Immunology
Publisher
Elsevier BV
Published
2011-12
Volume
128
Issue
6
Pages
1165-1174
ISSN
0091-6749 (ISSN-L)
OpenAlex
W1970703972
Cited by
343
References
13
FWCI
20.80
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Asthma exacerbations: Origin, effect, and prevention. https://app.cochat.ai/papers/10.1016/j.jaci.2011.10.024
The paper
Jackson, D. J., Sykes, A., Mallia, P., & Johnston, S. L. (2011). Asthma exacerbations: Origin, effect, and prevention. Journal of Allergy and Clinical Immunology. https://doi.org/10.1016/j.jaci.2011.10.024

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.