The DOI matches its Crossref record; 154 of the 155 references it cites were found in a registry or an index.
Environmental determinants of allergy and asthma in early life
Open accessAbstract
Allergic disease prevalence has increased significantly in recent decades. Primary prevention efforts are being guided by study of the exposome (or collective environmental exposures beginning during the prenatal period) to identify modifiable factors that affect allergic disease risk. In this review we explore the evidence supporting a relationship between key components of the external exposome in the prenatal and early-life periods and their effect on atopy development focused on microbial, allergen, and air pollution exposures. The abundance and diversity of microbial exposures during the first months and years of life have been linked with risk of allergic sensitization and disease. Indoor environmental allergen exposure during early life can also affect disease development, depending on the allergen type, dose, and timing of exposure. Recent evidence supports the role of ambient air pollution in allergic disease inception. The lack of clarity in the literature surrounding the relationship between environment and atopy reflects the complex interplay between cumulative environmental factors and genetic susceptibility, such that no one factor dictates disease development in all subjects. Understanding the effect of the summation of environmental exposures throughout a child's development is needed to identify cost-effective interventions that reduce atopy risk in children.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Allergic diseases, including asthma, are increasingly understood as multifactorial complex outcomes of genetic predisposition, environmental exposures, shaped by inflammatory and metabolic processes, host-microbiota interactions, and even epigenetic modifications (67–73).”
From Indoor Allergen Interventions in Homes and Schools for Managing Asthma (2025) · cites this paper as [67]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Dominguez-Bello, M. G., Costello, E. K., Contreras, M., Magris, M., Hidalgo, G., Fierer, N., & Knight, R. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002601107 · Cited by 4,774
Allergic Rhinitis and Its Impact on Asthma
Bousquet, J., van Cauwenberge, P., & Khaltaev, N. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.118891 · Cited by 3,588
Atopic Dermatitis: Global Epidemiology and Risk Factors
Nutten, S. (2015) · Annals of Nutrition and Metabolism · doi:10.1159/000370220 · Cited by 3,124
Wild, C. P. (2005) · Cancer Epidemiology, Biomarkers & Prevention · doi:10.1158/1055-9965.epi-05-0456 · Cited by 2,562
Factors influencing the composition of the intestinal microbiota in early infancy
Penders, J., Thijs, C., Vink, C., Stelma, F. F., Snijders, B., Kummeling, I., van den Brandt, P. A., & Stobberingh, E. E. (2006) · PEDIATRICS · doi:10.1542/peds.2005-2824 · Cited by 2,232
Environmental Exposure to Endotoxin and Its Relation to Asthma in School-Age Children
Braun‐Fahrländer, C., Riedler, J., Herz, U., Eder, W., Waser, M., Grize, L., Maisch, S., Carr, D., Gerlach, F., Bufe, A., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020057 · Cited by 1,818
Sporik, R., Holgate, S. T., Platts-Mills, T. A. E., & Cogswell, J. J. (1990) · New England Journal of Medicine · doi:10.1056/nejm199008233230802 · Cited by 1,648
The effect of air pollution on lung development from 10 to 18 years of age
Gauderman, W. J., Avol, E., Gilliland, F., Vora, H., Thomas, D., Berhane, K., McConnell, R., Kuenzli, N., Lurmann, F., Rappaport, E., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040610 · Cited by 1,440
Wheezing Rhinovirus Illnesses in Early Life Predict Asthma Development in High-Risk Children
Jackson, D. J., Gangnon, R. E., Evans, M. D., Roberg, K. A., Anderson, E. L., Pappas, T., Printz, M. C., Lee, W.-M., Shult, P. A., Reisdorf, E. S., et al. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200802-309oc · Cited by 1,310
Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing
Kalliomäki, M., Kirjavainen, P., Eerola, E., Kero, P., Salminen, S., & Isolauri, E. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.111237 · Cited by 1,255
Flagged first, then by citations
1 of the 155 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Air pollution and its effects on the immune system
Glencross, D. A., Ho, T.-R., Camiña, N., Hawrylowicz, C. M., & Pfeffer, P. E. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.01.179 · Cited by 726
The Burden of Pediatric Asthma
Ferrante, G., & Grutta, S. L. (2018) · Frontiers in Pediatrics · doi:10.3389/fped.2018.00186 · Cited by 485
Macrophage polarization and allergic asthma
Saradna, A., Do, D. C., Kumar, S. A., Fu, Q.-L., & Gao, P. (2017) · Translational research · doi:10.1016/j.trsl.2017.09.002 · Cited by 441
Sözener, Z. Ç., Öztürk, B. Ö., Çerçi, P., Türk, M., Akın, B. G., Akdiş, M., Altıner, S., Yücel, Ü. Ö., Öğülür, İ., Mitamura, Y., et al. (2022) · Allergy · doi:10.1111/all.15240 · Cited by 455
Environmental exposures and mechanisms in allergy and asthma development
Murrison, L. B., Brandt, E. B., Myers, J. M. B., & Hershey, G. K. K. (2019) · Journal of Clinical Investigation · doi:10.1172/jci124612 · Cited by 406
Donald, K., & Finlay, B. B. (2023) · Nature reviews. Immunology · doi:10.1038/s41577-023-00874-w · Cited by 394
External exposome and allergic respiratory and skin diseases
Cecchi, L., D’Amato, G., & Annesi‐Maesano, I. (2018) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2018.01.016 · Cited by 208
Climate change and global issues in allergy and immunology
Pacheco, S. E., Fogelbach, G. G., Annesi‐Maesano, I., Pawankar, R., D’Amato, G., Latour-Staffeld, P., Urrutia-Pereira, M., Kesic, M. J., & Hernandez, M. L. (2021) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2021.10.011 · Cited by 207
Self-citationSbihi, H., Boutin, R. C., Cutler, C., Suen, M., Finlay, B. B., & Turvey, S. E. (2019) · Allergy · doi:10.1111/all.13812 · Cited by 199
Selway, C. A., Mills, J. G., Weinstein, P., Skelly, C., Yadav, S., Lowe, A. J., Breed, M. F., & Weyrich, L. S. (2020) · Environment International · doi:10.1016/j.envint.2020.106084 · Cited by 179
House Dust Mite Allergy Under Changing Environments
Acevedo, N., Zakzuk, J., & Caraballo, L. R. (2019) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2019.11.4.450 · Cited by 168
Asthma and Obesity: Two Diseases on the Rise and Bridged by Inflammation
Bantulà, M., Roca‐Ferrer, J., Arismendi, E., & Picado, C. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10020169 · Cited by 160
Determinants of the urinary and serum metabolome in children from six European populations
Lau, C. E., Siskos, A., Maître, L., Robinson, O., Athersuch, T. J., Want, E. J., Urquiza, J., Casas, M., Vafeiadi, M., Roumeliotaki, T., et al. (2018) · BMC Medicine · doi:10.1186/s12916-018-1190-8 · Cited by 153
Sokołowska, M., Frei, R., Lunjani, N., Akdiş, C. A., & O’Mahony, L. (2018) · Asthma Research and Practice · doi:10.1186/s40733-017-0037-y · Cited by 152
Zuurveld, M., van Witzenburg, N. P., Garssen, J., Folkerts, G., Stahl, B., Land, B. V., & Willemsen, L. E. M. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00801 · Cited by 126
Han, X., Liu, L., Huang, S., Xiao, W., Gao, Y., Zhou, W., Zhang, C., Zheng, H., Yang, L., Xie, X., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-43219-w · Cited by 116
Intestinal permeability disturbances: causes, diseases and therapy
Macura, B., Kiecka, A., & Szczepanik, M. (2024) · Clinical and Experimental Medicine · doi:10.1007/s10238-024-01496-9 · Cited by 108
Transgenerational and intergenerational epigenetic inheritance in allergic diseases
Knudsen, T. M., Rezwan, F. I., Jiang, Y., Karmaus, W., Svanes, C., & Holloway, J. W. (2018) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2018.07.007 · Cited by 94
Air pollution significantly associated with severe ocular allergic inflammatory diseases
Miyazaki, D., Fukagawa, K., Fukushima, A., Fujishima, H., Uchio, E., Ebihara, N., Shoji, J., Takamura, E., Namba, K., Ohashi, Y., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-54841-4 · Cited by 88
Cook, Q., Argenio, K. L., & Lovinsky‐Desir, S. (2021) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2021.09.018 · Cited by 92
The neighbourhood natural environment is associated with asthma in children: A birth cohort study
Rufo, J. C., Paciência, I., Hoffimann, E., Moreira, A. M., Barros, H., & Ribeiro, A. I. (2020) · Allergy · doi:10.1111/all.14493 · Cited by 79
Global issues in allergy and immunology: Parasitic infections and allergy
Cruz, Á. A., Cooper, P. J., Figueiredo, C. A., Alcântara‐Neves, N. M., Rodrigues, L. C., & Barreto, M. L. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2017.09.005 · Cited by 82
Air pollutants may be environmental risk factors in chronic rhinosinusitis disease progression
Mady, L. J., Schwarzbach, H. L., Moore, J. A., Boudreau, R. M., Willson, T. J., & Lee, S. E. (2017) · International Forum of Allergy & Rhinology · doi:10.1002/alr.22052 · Cited by 79
Biological Therapies of Severe Asthma and Their Possible Effects on Airway Remodeling
Kardas, G., Kuna, P., & Panek, M. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01134 · Cited by 72
Zhang, Y., Wei, J., Shi, Y., Quan, C., Ho, H. C., Song, Y., & Zhang, L. (2021) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2021.02.030 · Cited by 69
The Respiratory Risks of Ambient/Outdoor Air Pollution
Adamkiewicz, G., Liddie, J. M., & Gaffin, J. M. (2020) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2020.08.013 · Cited by 79
Yu, L., Wang, B., Cheng, M., Yang, M., Gan, S., Fan, L., Wang, D., & Chen, W. (2020) · Indoor Air · doi:10.1111/ina.12657 · Cited by 71
Caraballo, L., Valenta, R., Puerta, L., Pomés, A., Zakzuk, J., Fernandez-Caldas, E., Acevedo, N., Sanchez-Borges, M., Ansotegui, I., Zhang, L., et al. (2020) · World Allergy Organization Journal · doi:10.1016/j.waojou.2020.100118 · Cited by 68
Wu, C., Zhang, Y., Wei, J., Zhao, Z., Norbäck, D., Zhang, X., Lu, C., Yu, W., Wang, T., Zheng, X., et al. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.36003 · Cited by 70
Lu, C., Norbäck, D., Li, Y., & Deng, Q. (2020) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2020.1804868 · Cited by 70
Warren, C. M., Turner, P., Chinthrajah, R. S., & Gupta, R. S. (2020) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2020.09.064 · Cited by 69
Urinary phthalate metabolites in relation to childhood asthmatic and allergic symptoms in Shanghai
Shi, W., Lin, Z., Liao, C., Zhang, J., Liu, W., Wang, X., Cai, J., Zou, Z., Wang, H., Norbäck, D., et al. (2018) · Environment International · doi:10.1016/j.envint.2018.08.043 · Cited by 64
Shang, Y., Sun, Y., Xu, J., Ge, X., Hu, Z., Xiao, J., Ning, Y., Dong, Y., & Bai, C. (2020) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2019.10.049 · Cited by 65
Monoclonal antibodies in the management of asthma: Dead ends, current status and future perspectives
Kardas, G., Panek, M., Kuna, P., Damiański, P., & Kupczyk, M. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.983852 · Cited by 62
van de Wetering, C., Elko, E. A., Berg, M., Schiffers, C., Stylianidis, V., van den Berge, M., Nawijn, M. C., Wouters, E. F. �., Janssen-Heininger, Y. M. W., & Reynaert, N. L. (2021) · Redox Biology · doi:10.1016/j.redox.2021.101995 · Cited by 64
Heterogeneity and the origins of asthma
Scherzer, R., & Grayson, M. H. (2018) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2018.06.009 · Cited by 57
Seal, S. V., & Turner, J. D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22073344 · Cited by 61
The role of epigenetics in the development of childhood asthma
Qi, C., Xu, C., & Koppelman, G. H. (2019) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2020.1686977 · Cited by 54
Rinaldi, A. O., Li, M., Barletta, E., D’Avino, P., Yazıcı, D., Pat, Y., Ward, S., Burla, D., Tan, G., Lord, N. A., et al. (2023) · Allergy · doi:10.1111/all.15891 · Cited by 52
Orešič, M., McGlinchey, A. J., Wheelock, C. E., & Hyötyläinen, T. (2020) · Metabolites · doi:10.3390/metabo10110454 · Cited by 52
Chiu, C., Cheng, M., Chiang, M., Wang, C., Tsai, M., & Lin, G. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9030887 · Cited by 48
Residential green space can shape the indoor microbial environment
Dockx, Y., Täubel, M., Bijnens, E. M., Witters, K., Valkonen, M., Jayaprakash, B., Hogervorst, J. G. F., Nawrot, T. S., & Casas, L. (2021) · Environmental Research · doi:10.1016/j.envres.2021.111543 · Cited by 48
Mélen, E., Koppelman, G., Vicedo-Cabrera, A., Andersen, Z. J., & Bunyavanich, S. (2022) · The Lancet Child & Adolescent Health · doi:10.1016/s2352-4642(22)00215-2 · Cited by 37
Nasal DNA methylation at three CpG sites predicts childhood allergic disease
van Breugel, M., Qi, C., Xu, Z., Pedersen, C. T., Petoukhov, I., Vonk, J. M., Gehring, U., Berg, M., Bügel, M., Carpaij, O. A., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-35088-6 · Cited by 49
Jeong, K. S., Kim, S., Kim, W. J., Kim, H., Bae, J., Hong, Y., Ha, M., Ahn, K., Lee, J., Kim, Y., et al. (2018) · Environmental Research · doi:10.1016/j.envres.2018.12.009 · Cited by 46
Kao, H.-F., Wang, Y.-C., Tseng, H.-Y., Wu, L. S.-H., Tsai, H., Hsieh, M.-H., Chen, P., Kuo, W.-S., Liu, L., Liu, Z.-G., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00184 · Cited by 47
Achieving Precision Medicine in Allergic Disease: Progress and Challenges
Proper, S. P., Azouz, N. P., & Baye, T. M. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.720746 · Cited by 45
The origins of allergy from a systems approach
Krempski, J. W., Dant, C. C., & Nadeau, K. C. (2020) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2020.07.013 · Cited by 41
Čelakovská, J., Bukač, J., Čermáková, E., Vaňková, R., Skalska, H., Krejsek, J., & Andrýs, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22105286 · Cited by 42
Ecosystem Restoration: A Public Health Intervention
Breed, M. F., Cross, A. T., Wallace, K. J., Bradby, K., Flies, E. J., Goodwin, N., Jones, M. E., Orlando, L. F., Skelly, C., Weinstein, P., et al. (2020) · EcoHealth · doi:10.1007/s10393-020-01480-1 · Cited by 40
Pediatric obesity and severe asthma: Targeting pathways driving inflammation
Cicco, M. D., Ghezzi, M., Kantar, A., Song, W., Bush, A., Peroni, D. G., & D’Auria, E. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106658 · Cited by 47
Paciência, I., Rufo, J. C., Silva, D., Martins, C., Mendes, F. C., Rama, T. A., Rodolfo, A., Madureira, J., Delgado, L., Fernandes, E. D. O., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-51659-y · Cited by 40
DEP-induced ZEB2 promotes nasal polyp formation via epithelial-to-mesenchymal transition
Lee, M., Lim, S., KIM, Y., Khalmuratova, R., Shin, S.-H., Kim, I., Kim, H. J., Kim, D., Rhee, C., Park, J., et al. (2021) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2021.04.024 · Cited by 40
Developmental origin and sex-specific risk for infections and immune diseases later in life
Zazara, D. E., & Arck, P. (2018) · Seminars in Immunopathology · doi:10.1007/s00281-018-0713-x · Cited by 40
Wei, Q., Zhong, L., Gao, J., Yi, W., Pan, R., Gao, J., Duan, J., Xu, Z., He, Y., Liu, X., et al. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.138206 · Cited by 39
Wheeze and Food Allergies in Children Born via Cesarean Delivery
Adeyeye, T. E., Yeung, E. H., McLain, A. C., Lin, S., Lawrence, D. A., & Bell, E. M. (2018) · American Journal of Epidemiology · doi:10.1093/aje/kwy257 · Cited by 38
Hosgood, H. D., Mongodin, E. F., Wan, Y., Hua, X., Rothman, N., Hu, W., Vermeulen, R. C. H., Seow, W. J., Rohan, T. E., Xu, J., et al. (2019) · Environmental and Molecular Mutagenesis · doi:10.1002/em.22291 · Cited by 37
Bedroom Allergen Exposure Beyond House Dust Mites
Salo, P. M., Cohn, R. D., & Zeldin, D. C. (2018) · Current Allergy and Asthma Reports · doi:10.1007/s11882-018-0805-7 · Cited by 37
The External Exposome and Food Allergy
Moran, T. P. (2020) · Current Allergy and Asthma Reports · doi:10.1007/s11882-020-00936-2 · Cited by 37
García‐Serna, A. M., Hernández‐Caselles, T., Jiménez‐Guerrero, P., Martín‐Orozco, E., Pérez‐Fernández, V., Cantero‐Cano, E., Muñoz‐García, M., Meseguer, C. B., Cobos, I. P. D. L., García‐Marcos, L., et al. (2020) · Environmental Research · doi:10.1016/j.envres.2020.110468 · Cited by 38
Nesbitt, H., Burke, C., & Haghi, M. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.713703 · Cited by 36
Kelderer, F., Mogren, I., Eriksson, C., Silfverdal, S., Domellöf, M., & West, C. E. (2022) · Pediatric Allergy and Immunology · doi:10.1111/pai.13848 · Cited by 33
Hummel, S., Weiß, A., Bonifacio, E. E., Agardh, D., Akolkar, B., Aronsson, C. A., Hagopian, W., Koletzko, S., Krischer, J. P., Lernmark, Å., et al. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab065 · Cited by 32
The shifting prevalence of asthma and allergic disease in US children
Pate, C. A., Zahran, H. S., Malilay, J., & Hsu, J. (2022) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2022.06.030 · Cited by 31
Subramanian, A., & Khatri, S. B. (2018) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2018.10.017 · Cited by 32
Interactions between environmental pollutants and genetic susceptibility in asthma risk
Johansson, H., Baye, T. M., Brandt, E. B., & Hershey, G. K. K. (2019) · Current Opinion in Immunology · doi:10.1016/j.coi.2019.07.010 · Cited by 30
Update in Pediatric Asthma: Selected Issues
Azmeh, R., Greydanus, D. E., Agana, M. G., Dickson, C. A., Patel, D. R., Ischander, M. M., & Lloyd, R. D. (2019) · Disease-a-Month · doi:10.1016/j.disamonth.2019.100886 · Cited by 34
Role of Environmental Air Pollution in Chronic Rhinosinusitis
Leland, E. M., Zhang, Z., Kelly, K. M., & Ramanathan, M. (2021) · Current Allergy and Asthma Reports · doi:10.1007/s11882-021-01019-6 · Cited by 36
Sun, Y., Xia, P., Xie, J., Mustieles, V., Zhang, Y., Wang, Y., & Messerlian, C. (2021) · European Respiratory Journal · doi:10.1183/13993003.01440-2021 · Cited by 30
The climate change hypothesis for the allergy epidemic
Rothenberg, M. E. (2022) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2022.02.006 · Cited by 30
Facteurs environnementaux favorisant le développement d’un asthme
Leynaert, B., Moual, N. L., Neukirch, C., Siroux, V., & Varraso, R. (2019) · La Presse Médicale · doi:10.1016/j.lpm.2019.02.022 · Cited by 36
Chen, T., Norbäck, D., Deng, Q., Huang, C., Qian, H., Zhang, X., Sun, Y., Wang, T., Zhang, Y., Li, B., et al. (2022) · Environment International · doi:10.1016/j.envint.2022.107315 · Cited by 28
Is early life adversity a trigger towards inflammageing?
Merz, M. P., & Turner, J. D. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111377 · Cited by 29
Indoor green can modify the indoor dust microbial communities
Dockx, Y., Täubel, M., Bijnens, E. M., Witters, K., Valkonen, M., Jayaprakash, B., Hogervorst, J. G. F., Nawrot, T. S., & Casas, L. (2022) · Indoor Air · doi:10.1111/ina.13011 · Cited by 27
Can the effects of outdoor air pollution on asthma be mitigated?
Stevens, E. L., Rosser, F. J., Forno, E., Peden, D. B., & Celedon, J. C. (2019) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2019.04.011 · Cited by 27
Self-citationIsolated Schistosoma mansoni eggs prevent allergic airway inflammation
Obieglo, K., Schuijs, M. J., Ozir‐Fazalalikhan, A., Otto, F., van Wijck, Y., Boon, L., Lambrecht, B. N., Taube, C., & Smits, H. H. (2018) · Parasite Immunology · doi:10.1111/pim.12579 · Cited by 26
A prenatally disrupted airway epithelium orchestrates the fetal origin of asthma in mice
Zazara, D. E., Wegmann, M., Giannou, A. D., Hierweger, A. M., Alawi, M., Thiele, K., Huber, S., Pincus, M., Muntau, A. C., Solano, M. E., et al. (2020) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2020.01.050 · Cited by 26
Chakraborty, P., Aravindhan, V., & Mukherjee, S. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.124649 · Cited by 28
Resende, S. D., Magalhães, F. C., Rodrigues, J. L., de Castro, V. N., de Souza, C. S. A., Oliveira, E., Carneiro, M., Geiger, S. M., & Negrão‐Corrêa, D. A. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2018.03158 · Cited by 27
Abdelzaher, H. M., Tawfik, S. M., Nour, A. A., Abdelkader, S., Elbalkiny, S. T., Abdelkader, M., Abbas, W. A., & Abdelnaser, A. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.973000 · Cited by 24
Microbial interactions in the atopic march
Nibbering, B., & Ubags, N. D. J. (2019) · Clinical & Experimental Immunology · doi:10.1111/cei.13398 · Cited by 24
Deng, X., Thurston, G. D., Zhang, W., Ryan, I., Jiang, C., Khwaja, H. A., Romeiko, X. X., Marks, T., Ye, B., Qu, Y., et al. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.144746 · Cited by 24
Worms: Pernicious parasites or allies against allergies?
McSorley, H. J., Chayé, M. A. M., & Smits, H. H. (2018) · Parasite Immunology · doi:10.1111/pim.12574 · Cited by 26
Yan, S., Wang, X., Yao, Z., Cheng, J., Ni, H., Xu, Z., Wei, Q., Pan, R., Yi, W., Jin, X., et al. (2021) · Environmental Research · doi:10.1016/j.envres.2021.112078 · Cited by 23
Tang, Z., Li, S., Shen, M., Xiao, Y., Su, J., Tao, J., Wang, X., Shan, S., Kang, X., Wu, B., et al. (2022) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2022.113932 · Cited by 23
Miller, R. L., Schuh, H. B., Chandran, A., Aris, I. M., Bendixsen, C. G., Blossom, J. C., Breton, C. V., Camargo, C. A., CANINO, G. J., Carroll, K. N., et al. (2023) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2023.03.016 · Cited by 22
Lu, C., Jiang, Y., Lan, M., Wang, L., Zhang, W., & Wang, F. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.134506 · Cited by 24
The Footprint of Microbiome in Pediatric Asthma—A Complex Puzzle for a Balanced Development
Lupu, A., Jechel, E., Mihai, C. M., Mitrofan, E. C., Fotea, S., Stârcea, I. M., Ioniuc, I. K., Mocanu, A., Ghica, D. C., Popp, A., et al. (2023) · Nutrients · doi:10.3390/nu15143278 · Cited by 22
The “envirome” and what the practitioner needs to know about it
Peden, D. B. (2019) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2019.09.014 · Cited by 23
Self-citationGuo, M., Wei, L., Yan, H., Duan, Z., Niu, Z., & Xiao, C. (2021) · International Journal of Environmental Health Research · doi:10.1080/09603123.2021.1929873 · Cited by 22
Feng, Y., Yang, C. Q., & Wen, Y. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.8414 · Cited by 21
Waye, K. P., Löve, J., Lercher, P., Dzhambov, A. M., Klatte, M., Schreckenberg, D., Belke, C., Leist, L., Ристовска, Г., Jeram, S., et al. (2023) · Environmental Research · doi:10.1016/j.envres.2023.117279 · Cited by 25
Kef, K., & Güven, S. G. (2020) · Journal of Asthma and Allergy · doi:10.2147/jaa.s279916 · Cited by 21
Respiratory Health Effects of Air Pollutants
Peden, D. B. (2023) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2023.07.004 · Cited by 21
Self-citationPrevention of Allergic Asthma with Allergen Avoidance Measures and the Role of Exposome
D’Amato, G., Monge-Ortega, O. P., Annesi‐Maesano, I., & D’Amato, M. (2020) · Current Allergy and Asthma Reports · doi:10.1007/s11882-020-0901-3 · Cited by 20
Olin, A., Acevedo, N., Lakshmikanth, T., Chen, Y., Johansson, C., Alm, J. S., Scheynius, A., & Brodin, P. (2022) · Allergy · doi:10.1111/all.15232 · Cited by 21
Wang, X., Zhou, N., & Zhi, Y. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2022.1097486 · Cited by 20
Air pollution and systemic immune biomarkers in early life: A systematic review
Carvajal, V., Molla, J. V. J., Luo, Y., Yu, Z., Moncunill, G., & Gascón, M. (2025) · Environmental Research · doi:10.1016/j.envres.2025.120838 · Cited by 19
Ferrante, G., Fasola, S., Cilluffo, G., PIACENTINI, G. L., Viegi, G., & Grutta, S. L. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.871140 · Cited by 22
Holuka, C., Grova, N., Charalambous, E. G., Cléac`H, J. L., Turner, J. D., & Mposhi, A. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105785 · Cited by 18
Metadata
- Authors
- Burbank, A. J., Sood, A. K., Kesic, M. J., Peden, D. B., & Hernandez, M. L.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Corresponding author
- Hernandez, Michelle L.
- Venue
- Journal of Allergy and Clinical Immunology
- Publisher
- Elsevier BV
- Published
- 2017-07
- Volume
- 140
- Issue
- 1
- Pages
- 1-12
- ISSN
- 0091-6749 (ISSN-L)
- PMC
- PMC5675123
- OpenAlex
- W2733928499
- Cited by
- 299
- References
- 155
- Citations by year
- 2026: 19 · 2025: 21 · 2024: 28 · 2023: 31 · 2022: 39 · 2021: 48 · 2020: 51 · 2019: 30 · 2018: 26 · 2017: 4
- FWCI
- 3.72
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Allergy and Clinical Immunology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
- UNC Libraries
- Funders
- American Academy of Allergy Asthma and Immunology
- National Institute of General Medical Sciences (T32GM086330)
- National Institute of Environmental Health Sciences (R01ES023349, K23ES021745, P30ES010126)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Keywords
- allergic diseases, asthma, exposome, prenatal exposure, early life exposure, atopy, allergen sensitization, microbial exposure, indoor allergens, ambient air pollution, environmental risk factors, genetic susceptibility, primary prevention
- MeSH terms
- Air Pollution, Allergens, Animals, Environmental Exposure, Humans, Hypersensitivity, Risk Factors, Microbiota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
