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Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): A multicenter, single-blind, randomized controlled trial
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Background Accumulating evidence proposed Janus-associated kinase (JAK) inhibitors as therapeutic targets warranting rapid investigation.Objective This study evaluated the efficacy and safety of ruxolitinib, a JAK1/2 inhibitor, for coronavirus disease 2019.Methods We conducted a prospective, multicenter, single-blind, randomized controlled phase II trial involving patients with severe coronavirus disease 2019.Results Forty-three patients were randomly assigned (1:1) to receive ruxolitinib plus standard-of-care treatment (22 patients) or placebo based on standard-of-care treatment (21 patients). After exclusion of 2 patients (1 ineligible, 1 consent withdrawn) from the ruxolitinib group, 20 patients in the intervention group and 21 patients in the control group were included in the study. Treatment with ruxolitinib plus standard-of-care was not associated with significantly accelerated clinical improvement in severe patients with coronavirus disease 2019, although ruxolitinib recipients had a numerically faster clinical improvement. Eighteen (90%) patients from the ruxolitinib group showed computed tomography improvement at day 14 compared with 13 (61.9%) patients from the control group (P = .0495). Three patients in the control group died of respiratory failure, with 14.3% overall mortality at day 28; no patients died in the ruxolitinib group. Ruxolitinib was well tolerated with low toxicities and no new safety signals. Levels of 7 cytokines were significantly decreased in the ruxolitinib group in comparison to the control group.Conclusions Although no statistical difference was observed, ruxolitinib recipients had a numerically faster clinical improvement. Significant chest computed tomography improvement, a faster recovery from lymphopenia, and favorable side-effect profile in the ruxolitinib group were encouraging and informative to future trials to test efficacy of ruxolitinib in a larger population.
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“However, ruxolitinib failed to show significant protection in the treatment of severe coronavirus disease (57) and the National Institutes of Health recommends against using ruxolitinib for the treatment of COVID-19 (https://bit.ly/3TtgsIe).”
From DrugCentral 2023 extends human clinical data and integrates veterinary drugs (2023) · cites this paper as [57]
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30183-5 · Cited by 48,884
Self-citationClinical characteristics of coronavirus disease 2019 in China
Guan, W.-J., Ni, Z.-Y., Hu, Y., Liang, W.-H., Ou, C.-Q., He, J.-X., Liu, L., Shan, H., Lei, C.-L., Hui, D. S. C., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2002032 · Cited by 30,246
Self-citationA novel coronavirus from patients with pneumonia in China, 2019
Zhu, N., Zhang, D., Wang, W., Li, X., Yang, B., Song, J., Zhao, X., Huang, B., Shi, W., Lu, R., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2001017 · Cited by 28,244
Self-citationChen, N., Zhou, M., Dong, X., Qu, J., Gong, F., Han, Y., Qiu, Y., Wang, J., Liu, Y., Wei, Y., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30211-7 · Cited by 21,415
Wang, D., Hu, B., Hu, C., Zhu, F., Liu, X., Zhang, J., Wang, B., Xiang, H., Cheng, Z., Xiong, Y., et al. (2020) · JAMA · doi:10.1001/jama.2020.1585 · Cited by 20,148
La certeza de lo impredecible: Cultura Educación y Sociedad en tiempos de COVID19
Martínez González, M. (2020) · DSPACE System - Metalibrary (University of the Coast) · Cited by 18,463
Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia
Li, Q., Guan, X., Wu, P., Wang, X., Zhou, L., Tong, Y., Ren, R., Leung, K. S. M., Lau, E. H. Y., Wong, J. Y., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2001316 · Cited by 16,575
Self-citationPathological findings of COVID-19 associated with acute respiratory distress syndrome
Xu, Z., Shi, L., Wang, Y., Zhang, J., Huang, L., Zhang, C., Liu, S., Zhao, P., Liu, H., Zhu, L., et al. (2020) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(20)30076-x · Cited by 8,545
Self-citationA Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
Cao, B., Wang, Y., Wen, D., Liu, W., Wang, J., Fan, G., Ruan, L., Song, B., Cai, Y., Wei, M., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2001282 · Cited by 5,258
Self-citationVEGF receptor signalling ? in control of vascular function
Olsson, A.-K., Dimberg, A., Kreuger, J., & Claesson-Welsh, L. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1911 · Cited by 3,122
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- Yan, 2020, Evolution characteristics of thoracic lesions on CT of COVID-19 in recovery stage [in Chinese], Radiol Pract, 35, 428
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Tseng, P., Zeng, B., Hsu, C., Thompson, T., Stubbs, B., Hsueh, P., Su, K., Chen, Y., Chen, T., Wu, Y., et al. (2023) · Journal of the Royal Society of Medicine · doi:10.1177/01410768231202657 · Cited by 4
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Muzaffar, U., Fakiruddin, K. S., Talebiashtiany, Y., & Abdullah, S. (2025) · Cytokine · doi:10.1016/j.cyto.2025.157025 · Cited by 3
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Li, J., Long, X., Zhang, Q., Fang, X., Luo, H., Fang, F., Lv, X., Zhang, D., Sun, Y., Li, N., et al. (2022) · iScience · doi:10.1016/j.isci.2022.104415 · Cited by 3
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Yang, J., Zhang, Z., Liu, H., Wang, J., Xie, S., Li, P., Wen, J., Wei, S., Li, R., Ma, X., et al. (2023) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/0113862073236899230919062725 · Cited by 1
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Rojas, P., & Mauricio Sarmiento, M. (2020) · Revista médica de Chile · doi:10.4067/s0034-98872020001101640 · Cited by 1
Fhatonah, N., Ma’sum, Dewianti, Z. P., Nuraini, N., & Rusdiana, N. (2021) · Advances in health sciences research/Advances in Health Sciences Research · doi:10.2991/ahsr.k.210115.114 · Cited by 1
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Kabbani, D., Sonpar, A., Weyant, R. B., Lau, K. C. K., Robbins, M., Campbell, S., Doucette, K. E., Abraldeṣ, J. G., Lotfi, T., Chaktoura, M., et al. (2021) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofac655 · Cited by 1
Fukuda, Y., Mochizuki, K., Ijichi, M., Homma, T., Tanaka, A., & Sagara, H. (2023) · Cureus · doi:10.7759/cureus.43179 · Cited by 1
Li, Y., & He, W. (2020) · medRxiv · doi:10.1101/2020.11.16.20232884 · Cited by 1
Miller, A., & D'Silva, Y. A. (2021) · International Journal of Critical Illness and Injury Science · doi:10.4103/ijciis.ijciis_80_21 · Cited by 1
(2020) · Revista Paulista de Reumatologia · doi:10.46833/reumatologiasp.2020.19.3 · Cited by 1
Joshy, A. S., Thomas, C., Surendran, S., & Undela, K. (2022) · medRxiv · doi:10.1101/2022.04.15.22273881 · Cited by 1
Laurence, A. D. J., Gadina, M., Schwartzberg, P. L., & O’Shea, J. J. (2023) · Elsevier eBooks · doi:10.1016/b978-0-7020-8165-1.00085-x · Cited by 1
Amstutz, A., Schandelmaier, S., Ewald, H., Speich, B., Schwenke, J. M., Schönenberger, C., Schobinger, S., Agoritsas, T., Tomashek, K. M., Nayak, S., et al. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4974193 · Cited by 1
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Metadata
- Authors
- Cao, Y., Wei, J., Zou, L., Jiang, T., Wang, G., Chen, L., Huang, L., Meng, F., Huang, L., Wang, N., Zhou, X., Luo, H., Mao, Z., Chen, X., Xie, J., Liu, J., Cheng, H., Zhao, J., Huang, G., Wang, W., & Zhou, J.
- Affiliations
- Tongji Hospital (CN)
- Wuhan No.1 Hospital (CN)
- Third Xiangya Hospital (CN)
- Cincinnati Children's Hospital Medical Center (US)
- Corresponding author
- Huang, Gang
- Wang, Wei
- Zhou, Jianfeng
- ORCID
- Venue
- Journal of Allergy and Clinical Immunology
- Publisher
- Elsevier BV
- Published
- 2020-07
- Volume
- 146
- Issue
- 1
- Pages
- 137-146.e3
- ISSN
- 0091-6749 (ISSN-L)
- PMC
- PMC7250105
- OpenAlex
- W3030158388
- Cited by
- 456
- References
- 38
- Citations by year
- 2026: 2 · 2025: 9 · 2024: 24 · 2023: 45 · 2022: 95 · 2021: 178 · 2020: 103
- FWCI
- 14.05
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Allergy and Clinical Immunology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Emergency Research Project of Tongji Hospital
- Emergency Research Project of Tongji Hospital of Huazhong University of Science and Technology (2020kfyXGYJ045)
- Emergency Research Project of Hubei province (2020FCA006)
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
- Keywords
- ruxolitinib, COVID-19 pandemic, severe COVID-19, JAK1/2 inhibitor, JAK inhibitors, cytokine levels, mortality, drug safety, antiviral therapy
- MeSH terms
- Betacoronavirus, Janus Kinase Inhibitors, COVID-19, SARS-CoV-2, COVID-19 Drug Treatment, Aged, Female, Humans, Male, Middle Aged, Nitriles, Pneumonia, Viral, Pyrazoles, Pyrimidines, Single-Blind Method, Treatment Outcome, Coronavirus Infections, Pandemics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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