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Cited by 588Psychotherapy Techniques and ApplicationsTreatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.

The effects of psychotherapies for major depression in adults on remission, recovery and improvement: A meta-analysis

Cuijpers, Pim, Karyotaki, Eirini, Weitz, Erica, Andersson, Gerhard, Hollon, Steven D., van Straten, Annemieke·2014·Journal of Affective Disorders
DOI 10.1016/j.jad.2014.02.026
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Abstract

Background Standardised effect sizes have been criticized because they are difficult to interpret and offer little clinical information. This meta-analyses examine the extent of actual improvement, the absolute numbers of patients no longer meeting criteria for major depression, and absolute rates of response and remission.Methods We conducted a meta-analysis of 92 studies with 181 conditions (134 psychotherapy and 47 control conditions) with 6937 patients meeting criteria for major depressive disorder. Within these conditions, we calculated the absolute number of patients no longer meeting criteria for major depression, rates of response and remission, and the absolute reduction on the BDI, BDI-II, and HAM-D.Results After treatment, 62% of patients no longer met criteria for MDD in the psychotherapy conditions. However, 43% of participants in the control conditions and 48% of people in the care-as-usual conditions no longer met criteria for MDD, suggesting that the additional value of psychotherapy compared to care-as-usual would be 14%. For response and remission, comparable results were found, with less than half of the patients meeting criteria for response and remission after psychotherapy. Additionally, a considerable proportion of response and remission was also found in control conditions. In the psychotherapy conditions, scores on the BDI were reduced by 13.42 points, 15.12 points on the BDI-II, and 10.28 points on the HAM-D. In the control conditions, these reductions were 4.56, 4.68, and 5.29.Discussion Psychotherapy contributes to improvement in depressed patients, but improvement in control conditions is also considerable.

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Metadata

Authors
Cuijpers, P., Karyotaki, E., Weitz, E., Andersson, G., Hollon, S. D., & van Straten, A.
Affiliations
  • Leuphana University of Lüneburg (DE)
  • Amsterdam Public Health (NL)
  • Linköping University (SE)
  • Vanderbilt University (US)
Corresponding author
Cuijpers, Pim
ORCID
Venue
Journal of Affective Disorders
Publisher
Elsevier BV
Published
2014-04
Volume
159
Pages
118-126
ISSN
0165-0327 (ISSN-L)
DOI
10.1016/j.jad.2014.02.026
OpenAlex
W2141305471
Semantic Scholar
f373e105af3f5363f14fc4a4eb88392a9bf0eafa
Cited by
586
References
31
Citations by year
2026: 53 · 2025: 84 · 2024: 65 · 2023: 47 · 2022: 46 · 2021: 87 · 2020: 37 · 2019: 44 · 2018: 38 · 2017: 26 · 2016: 30 · 2015: 22 · 2014: 6
FWCI
4.26
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Affective Disorders (publishedVersion)
  • PubMed (publishedVersion)
  • Multilingual Matters (Channel View Publications) (submittedVersion)
  • VU Research Portal (submittedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
  • Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
major depressive disorder, psychotherapy, remission, response rate, usual care, Beck Depression Inventory, Hamilton Depression Rating Scale
MeSH terms
Adult, Major Depressive Disorder, Humans, Psychotherapy, Randomized Controlled Trials as Topic, Treatment Outcome

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