Cited by 137Suicide and Self-Harm StudiesPsychiatric care and mental health servicesSubstance Abuse Treatment and Outcomes

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Interventions to prevent repeat suicidal behavior in patients admitted to an emergency department for a suicide attempt: a meta-analysis.

Inagaki, Masatoshi, Kawashima, Yoshitaka, Kawanishi, Chiaki, Yonemoto, Naohiro, Sugimoto, Tatsuya, Furuno, Taku, Ikeshita, Katsumi, Eto, Nobuaki, Tachikawa, Hirokazu, Shiraishi, Yohko, Yamada, Mitsuhiko·2015·Journal of Affective Disorders

DOI 10.1016/j.jad.2014.12.048

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Abstract

Background A huge number of patients with self-harm and suicide attempt visit emergency departments (EDs). We systematically reviewed studies and examined the effect of interventions to prevent repeat suicidal behavior in patients admitted to EDs for a suicidal attempt.Method We searched the databases of MEDLINE, PsychoINFO, CINAHL, and EMBASE through August 2013. Eligible studies were randomized controlled trials assessing the effects on repeat suicidal behavior of interventions initiated in suicidal patients admitted to EDs. Interventions in each trial were classified into groups by consensus. Meta-analyses were performed to determine pooled relative risks (RRs) and 95% confidence intervals (CIs) of repetition of suicide attempt for interventions in each group.Results Out of 5390 retrieved articles, 24 trials were included and classified into four groups (11 trials in the Active contact and follow-up, nine in the Psychotherapy, one in the Pharmacotherapy, and three in the Miscellaneous). Active contact and follow-up type interventions were effective in preventing a repeat suicide within 12 months (n=5319; pooled RR=0.83; 95% CI: 0.71 to 0.97). However, the effect at 24 months was not confirmed (n=925; pooled RR=0.98; 95% CI: 0.76-1.22). The effects of the other interventions on preventing a repetition of suicidal behavior remain unclear.Limitation Caution is needed regarding the heterogeneity of the effects.Conclusion Interventions of active contact and follow-up are recommended to reduce the risk of a repeat suicide attempt at 12 months in patients admitted to EDs with a suicide attempt. However, the long-term effect was not confirmed.

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Self-citation

Authors: Inagaki, M., Kawashima, Y., Kawanishi, C., Yonemoto, N., Sugimoto, T., Furuno, T., Ikeshita, K., Eto, N., Tachikawa, H., Shiraishi, Y., & Yamada, M.
Affiliations: Okayama University Hospital (JP)
National Center of Neurology and Psychiatry (JP)
Yokohama City University (JP)
Tokyo Metropolitan Matsuzawa Hospital (JP)
National Hospital Organization Yokohama Medical Center (JP)
Nara Medical University (JP)
Fukuoka University (JP)
University of Tsukuba (JP)
Corresponding author: Inagaki, Masatoshi
ORCID: Inagaki, Masatoshi
Kawashima, Yoshitaka
Kawanishi, Chiaki
Yonemoto, Naohiro
Sugimoto, Tatsuya
Furuno, Taku
Ikeshita, Katsumi
Tachikawa, Hirokazu
Shiraishi, Yohko
Yamada, Mitsuhiko
Venue: Journal of Affective Disorders
Publisher: Elsevier BV
Published: 2015-04
Volume: 175
Pages: 66-78
ISSN: 0165-0327 (ISSN-L)
DOI: 10.1016/j.jad.2014.12.048
OpenAlex: W2064971250
Cited by: 137
References: 74
Citations by year: 2026: 6 · 2025: 6 · 2024: 14 · 2023: 11 · 2022: 19 · 2021: 9 · 2020: 21 · 2019: 11 · 2018: 16 · 2017: 10 · 2016: 11 · 2015: 3
FWCI: 1.22
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Affective Disorders (publishedVersion)
PubMed (publishedVersion)
Funders: Mochida Pharmaceutical Company
Japan Society for the Promotion of Science (26461771)
Japan Science and Technology Agency
Topics: Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords: suicide attempts, suicide prevention, emergency department, follow-up intervention, psychotherapy, pharmacotherapy, self-harm, long-term outcomes
MeSH terms: Suicide Prevention, Emergency Service, Hospital, Humans, Suicide, Suicide, Attempted, Randomized Controlled Trials as Topic, Treatment Outcome, Protective Factors

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Interventions to prevent repeat suicidal behavior in patients admitted to an emergency department for a suicide attempt: a meta-analysis.

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