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Cited by 286

The DOI matches its Crossref record; 77 of the 77 references it cites were found in a registry or an index.

Overweight, Obesity, and Lung Function in Children and Adults—A Meta-analysis

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Forno, Erick, Han, Yueh-Ying, Mullen, James, Celedón, Juan C.·2018·The Journal of Allergy and Clinical Immunology: In Practice

Abstract

Background There is conflicting evidence on the effect of obesity on lung function in adults and children with and without asthma. We aimed to evaluate the relation between overweight or obesity and lung function, and whether such relationship varies by age, sex, or asthma status. Methods We searched PubMed, Scopus, CINAHL, Cochrane, and EMBASE for all studies (in English) reporting on obesity status (by BMI) and lung function, from 2005 to 2017. Main outcomes were FEV1, FVC, FEV1/FVC, FEF25-75, TLC, RV, and FRC. Random-effects models were used to calculate the pooled risk estimates; each study was weighed by the inverse effect size variance. For each outcome, we compared overweight or obese (“obese”) subjects with those of normal weight. Results All measures of lung function were decreased among obese subjects. Obese adults showed a pattern (lower FEV1, FVC, TLC, and RV) different from obese children (more pronounced FEV1/FVC deficit with unchanged FEV1 or FVC). There were also seemingly different patterns by asthma status, in that subjects without asthma had more marked decreases in FEV1, TLC, RV and FRC than subjects with asthma. Subjects who were obese (as compared to overweight) had even further decreased FEV1, FVC, TLC, RV, and FRC. Conclusion Obesity is detrimental to lung function, but specific patterns differ between children and adults. Physicians should be aware of adverse effects of obesity on lung function, and weight-control should be considered in the management of airway disease among the obese.

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Metadata

Authors
Forno, E., Han, Y.-Y., Mullen, J., & Celedón, J. C.
Venue
The Journal of Allergy and Clinical Immunology: In Practice
Publisher
Elsevier BV
Published
2018-03
Volume
6
Issue
2
Pages
570-581.e10
ISSN
2213-2198 (ISSN-L)
OpenAlex
W2759448078
Cited by
286
References
77
FWCI
4.25
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Overweight, Obesity, and Lung Function in Children and Adults—A Meta-analysis. https://app.cochat.ai/papers/10.1016/j.jaip.2017.07.010
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Forno, E., Han, Y.-Y., Mullen, J., & Celedón, J. C. (2018). Overweight, Obesity, and Lung Function in Children and Adults—A Meta-analysis. The Journal of Allergy and Clinical Immunology: In Practice. https://doi.org/10.1016/j.jaip.2017.07.010

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