The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
Inequalities in dementia incidence between six racial and ethnic groups over 14 years
Open accessAbstract
Introduction: Reducing racial/ethnic disparities is a primary objective of the National Alzheimer's Plan (NAPA), yet direct comparisons within large samples representing diversity of the United States are lacking. Methods: Dementia incidence from January 1, 2000 to December 31, 2013 and a 25‐year cumulative risk in 274,283 health care members aged 64+ (n = 18,778 African‐American, n = 4543 American Indian/Alaska Native [AIAN], n = 21,000 Latino, n = 440 Pacific Islander, n = 206,490 white, n = 23,032 Asian‐Americans). Cox proportional hazard models were adjusted for age, sex, medical utilization, and comorbidities. Results: Dementia incidence (n = 59,555) was highest for African‐Americans (26.6/1000 person‐years) and AIANs (22.2/1000 person‐years); intermediate for Latinos (19.6/1000 person‐years), Pacific Islanders (19.6/1000 person‐years), and whites (19.3/1000 person‐years) and lowest among Asian‐Americans (15.2/1000 person‐years). Risk was 65% greater for African‐Americans (hazard ratio = 1.65; 95% confidence interval = 1.58–1.72) versus Asian‐Americans. Cumulative 25‐year risk at age 65 was as follows: 38% African‐Americans, 35% AIANs, 32% Latino, 25% Pacific Islanders, 30% white, and 28% Asian‐Americans. Discussion: Dementia rates varied over 60% between groups, providing a comprehensive benchmark for the NAPA goal of reducing disparities.
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“Its findings indicated that dementia incidence — determined by the first presence of a dementia diagnosis in members’ medical records — was highest among African American older adults (the term used in the study for those who self‐reported as Black or African‐American); intermediate for Latino older adults (the term used in the study for those who self‐reported as Latino or Hispanic), American”
From 2024 Alzheimer's disease facts and figures (2024) · cites this paper as [347]
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Citations
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Rkinjuntti, T. I. E., Stbye, T. R. Ø., Teenhuis, R. U. S., & Achinski, V. L. H. (1997) · Cited by 315
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“Reducing racial/ethnic disparities in dementia has been identified as a national priority by both the National Alzheimer’s Plan (NAPA) [1] and the Alzheimer’s DiseaseRelated Dementias Conference [2] road maps.”
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“05 [31].”
Katon, W. J., Lin, E. H. B., Williams, L. H., Ciechanowski, P., Heckbert, S. R., Ludman, E., Rutter, C., Crane, P. K., Oliver, M., & Von Korff, M. (2010) · Journal of General Internal Medicine · doi:10.1007/s11606-009-1248-6 · Cited by 141 · cited 1×
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Plassman, B. L., Langa, K. M., Fisher, G. G., Heeringa, S. G., Weir, D. R., Ofstedal, M. B., Burke, J. R., Hurd, M. D., Potter, G. G., Rodgers, W. L., et al. (2007) · Cited by 139
Impediments to Timely Diagnosis of Alzheimer's Disease in African Americans
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“Reducing racial/ethnic disparities in dementia has been identified as a national priority by both the National Alzheimer’s Plan (NAPA) [1] and the Alzheimer’s DiseaseRelated Dementias Conference [2] road maps.”
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Shadlen, M., Siscovick, D. S., Fitzpatrick, A. L., Dulberg, C. S., Kuller, L. H., & Jackson, S. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2006.00747.x · Cited by 110 · cited 1×
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ResultFrequency of Alzheimer's Disease and Other Dementias in a Community Outreach Sample of Hispanics
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“We did not have measures of education in the present study, but educational patterns among older Californians do not strictly follow the observed patterns of dementia risk.”
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Self-citationRacial and Ethnic Disparities in Health and Mortality Among the U.S. Elderly Population
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Validation of a polygenic risk score for dementia in black and white individuals
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“For example, the prevalence of the APOE ε4 allele is higher among AfricanAmericans than among whites, but the relative risk of dementia associated with the ε4 allele is smaller among African-Americans compared with whites [14,44–47].”
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“A study of Japanese American men in Hawaii and a study of Japanese Americans in Washington reported similar or lower dementia incidence among Japanese Americans compared with dementia incidence among whites in other studies [17,18].”
ResultHigh Rates of Native Hawaiian and Older Japanese Adults Hospitalized with Dementia in Hawai‘i
Sentell, T. L., Valcour, N., Ahn, H. J., Miyamura, J., Nakamoto, B. K., Chow, D. C., Masaki, K., Seto, T. B., Chen, J. J., & Shikuma, C. M. (2014) · Journal of the American Geriatrics Society · doi:10.1111/jgs.13182 · Cited by 30
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Metadata
- Authors
- Mayeda, E. R., Glymour, M. M., Quesenberry, C. P., & Whitmer, R. A.
- Affiliations
- University of California, San Francisco (US)
- Kaiser Permanente (US)
- Corresponding author
- Whitmer, Rachel A.
- Venue
- Alzheimer's & Dementia
- Publisher
- Wiley
- Published
- 2016-02-10
- Volume
- 12
- Issue
- 3
- Pages
- 216-224
- ISSN
- 1552-5260 (ISSN-L)
- 1552-5279
- PMC
- PMC4969071
- OpenAlex
- W2266863819
- Cited by
- 883
- References
- 51
- Citations by year
- 2026: 98 · 2025: 109 · 2024: 112 · 2023: 113 · 2022: 113 · 2021: 100 · 2020: 96 · 2019: 66 · 2018: 41 · 2017: 27 · 2016: 7
- FWCI
- 41.77
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Alzheimer s & Dementia (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institute on Aging
- National Institutes of Health
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Health › Health disparities and outcomes
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Keywords
- dementia incidence, racial and ethnic disparities
- MeSH terms
- Age Factors, Aged, Aged, 80 and over, Black or African American, Delivery of Health Care, Dementia, Ethnicity, Female, Hispanic or Latino, Humans, Indians, North American, Longitudinal Studies, Male, Middle Aged, Sex Factors, Socioeconomic Factors, United States, Incidence, Proportional Hazards Models, White People
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