The DOI matches its Crossref record; 495 of the 496 references it cites were found in a registry or an index.
2019 Alzheimer’s disease facts and figures.
Abstract
This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, use and costs of care, and the overall impact on caregivers and society. The Special Report examines the use of brief cognitive assessments by primary care physicians as a tool for improving early detection of dementia. An estimated 5.8 million Americans have Alzheimer's dementia. By mid‐century, the number of people living with Alzheimer's dementia in the United States may grow to 13.8 million, fueled in large part by the aging baby boom generation. In 2017, official death certificates recorded 121,404 deaths from AD, making AD the sixth leading cause of death in the United States and the fifth leading cause of death among Americans age ≥65 years. Between 2000 and 2017, deaths resulting from stroke, heart disease, and prostate cancer decreased, whereas reported deaths from AD increased 145%. In 2018, more than 16 million family members and other unpaid caregivers provided an estimated 18.5 billion hours of care to people with Alzheimer's or other dementias. This care is valued at nearly $234 billion, but its costs extend to family caregivers' increased risk for emotional distress and negative mental and physical health outcomes. Average per‐person Medicare payments for services to beneficiaries age ≥65 years with Alzheimer's or other dementias are more than three times as great as payments for beneficiaries without these conditions. Total payments in 2019 for health care, long‐term care and hospice services for people age ≥65 years with dementia are estimated to be $290 billion. Early detection of Alzheimer's offers numerous medical, emotional and financial benefits—benefits that accrue to affected individuals and their families as well as to society at large. Alzheimer's Association surveys regarding brief cognitive assessments for detection of dementia found that while a large majority of seniors and primary care physicians say the assessments are important, only half of seniors have received an assessment, and only 16 percent of seniors receive regular cognitive assessments. Many educational opportunities exist to facilitate increased use of brief cognitive assessments in the primary care setting.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“precise identification of FTD and AD, which are the two most common types of dementia in the younger-elderly population (Bang et al., 2015; Association, 2019), is of vital clinical significance in the diagnosis of dementias.”
From Deep Learning-Based Classification and Voxel-Based Visualization of Frontotemporal Dementia and Alzheimer's Disease (2021) · cites this paper as Association, 2019
Citations
Cites
McKhann, G. M., Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, C. R., Kawas, C. H., Klunk, W. E., Koroshetz, W. J., Manly, J. J., Mayeux, R., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.005 · Cited by 18,657
ASSESSMENT OF COMA AND IMPAIRED CONSCIOUSNESS
Teasdale, G., & Jennett, B. (1974) · The Lancet · doi:10.1016/s0140-6736(74)91639-0 · Cited by 13,215
Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.617 · Cited by 12,052
Albert, M. S., DeKosky, S. T., Dickson, D., Dubois, B., Feldman, H. H., Fox, N. C., Gamst, A., Holtzman, D. M., Jagust, W. J., Petersen, R. C., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.008 · Cited by 10,152
Sperling, R. A., Aisen, P. S., Beckett, L. A., Bennett, D. A., Craft, S., Fagan, A. M., Iwatsubo, T., Jack, C. R., Kaye, J., Montine, T. J., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.003 · Cited by 7,155
Dementia prevention, intervention, and care
Livingston, G., Sommerlad, A., Orgeta, V., Costafreda, S. G., Huntley, J., Ames, D., Ballard, C., Banerjee, S., Burns, A., Cohen-Mansfield, J., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)31363-6 · Cited by 6,072
International Statistical Classification of Diseases and Related Health Problems
(2010) · Springer eBooks · doi:10.1007/978-0-387-79948-3_3055 · Cited by 4,182
What is cognitive reserve? Theory and research application of the reserve concept
STERN, Y. (2002) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617702813248 · Cited by 3,951
Clinical and biomarker changes in dominantly inherited Alzheimer's disease
Bateman, R. J., Xiong, C., Benzinger, T. L. S., Fagan, A. M., Goate, A., Fox, N. C., Marcus, D. S., Cairns, N. J., Xie, X., Blazey, T. M., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1202753 · Cited by 3,814
Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease
Saunders, A. M., Strittmatter, W. J., Schmechel, D., St. George-Hyslop, P. H., Pericak-Vance, M. A., Joo, S. H., Rosi, B. L., Gusella, J. F., Crapper-MacLachlan, D. R., Alberts, M. J., et al. (1993) · Neurology · doi:10.1212/wnl.43.8.1467 · Cited by 3,786
Research works printed but not linked: 26
- Grossberg GT, 2010, The art of sharing the diagnosis and management of Alzheimer's disease with patients and caregivers: Recommendations of an expert consensus panel, Prim Care Companion J Clin Psychiatry, 12
- 2015, Cognitive Aging: Progress in Understanding and Opportunity for Action
- Sajeev G, Diabetes. The AlzRisk Database. Alzheimer Research Forum
- Steptoe A, 2005, Aging, Health, and Public Policy
- He W, 2016, International Population Reports, P95/16‐1, An Aging World: 2015
- 2006, Early‐Onset Dementia: A National Challenge, a Future Crisis
- Manly JJ, 2004, Critical perspectives on racial and ethnic differentials in health in late life, 95
- Prince MJ, 2015, World Alzheimer Report 2015: The Global Impact of Dementia: An Analysis of Prevalence
- Ortman JM, 2014, An Aging Nation: The Older Population in the United States, Current Population Reports, P25‐1140
- Heron M, 2018, Deaths: Leading causes for 2016
- Kasper JD, 2014, Disability and Care Needs of Older Americans by Dementia Status: An Analysis of the 2011 National Health and Aging Trends Study
- Maslow K, 2012, Translating Innovation to Impact: Evidence‐Based Interventions to Support People with Alzheimer's Disease and their Caregiver at Home and in the Community
- Zarit SH, 2009, Aging families and caregiving, 131
- Whitlatch CJ, 2018, Meeting the informational, educational, and psychosocial support needs of persons living with dementia and their family caregivers, Gerontologist, 58, S58
- Khatutsky G, 2011, Understanding direct care workers: A snapshot of two of America's most important jobs: Certified nursing assistants and home health aides
- Stone R, 2012, Universal Coverage of Long‐Term Care in the United States: Can We Get There from Here?, 155
- Eldercare Workforce Alliance, 2012, Geriatrics Workforce Shortage: A Looming Crisis for our Families
- National Academies of Sciences, 2016, Engineering, and Medicine. Families Caring for an Aging America
- Eiken S, 2018, Medicaid Expenditures for Long‐Term Services and Supports in FY 2016. IAP Medicaid Innovation Accelerator Program
- Bynum J, 2009, Unpublished; provided under contract with the Alzheimer's Association
- Jacobson G, 2017, Income and Assets of Medicare Beneficiaries, 2016‐2035
- National Association of Insurance Commissioners and the Center for Insurance Policy and Research, 2016, The State of Long‐Term Care Insurance: The Market, Challenges and Future Innovations
- Reaves EL, 2015, Medicaid and Long‐Term Services and Supports: A Primer
- 10.1111/j.1525-1497.2005.0126.x · DOI
- Albert SM, 2010, The MetLife Study of working caregivers and employer health care costs
- Shriver M, 2010, The Shriver Report: A Woman's Nation Takes on Alzheimer's
Cited by
Sorted by citations
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
Long, J. M., & Holtzman, D. M. (2019) · Cell · doi:10.1016/j.cell.2019.09.001 · Cited by 3,204
2021 Alzheimer's disease facts and figures
Anonymous (2021) · Alzheimer s & Dementia · doi:10.1002/alz.12328 · Cited by 2,339
Sex and gender: modifiers of health, disease, and medicine
Mauvais-Jarvis, F., Bairey Merz, N., Barnes, P. J., Brinton, R. D., Carrero, J.-J., DeMeo, D. L., De Vries, G. J., Epperson, C. N., Govindan, R., Klein, S. L., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)31561-0 · Cited by 2,001
Diagnosis and Management of Dementia: Review
Arvanitakis, Z., Shah, R. C., & Bennett, D. A. (2019) · JAMA · doi:10.1001/jama.2019.4782 · Cited by 1,561
López, J. A., González, H. M., & Léger, G. C. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-12-804766-8.00013-3 · Cited by 887
Metadata
- Authors
- Alzheimer's Association
- Corresponding author
- Alzheimer's Association
- Venue
- Alzheimer's & Dementia
- Publisher
- Wiley
- Published
- 2019-03
- Volume
- 15
- Issue
- 3
- Pages
- 321-387
- ISSN
- 1552-5260 (ISSN-L)
- 1552-5279
- OpenAlex
- W4211139529
- Cited by
- 2,461
- References
- 496
- Citations by year
- 2026: 108 · 2025: 214 · 2024: 245 · 2023: 310 · 2022: 357 · 2021: 558 · 2020: 544 · 2019: 120
- FWCI
- 316.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Alzheimer s & Dementia (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Geriatrics and Gerontology › Geriatric Care and Nursing Homes
- Keywords
- Alzheimer's disease, dementia
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review