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Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation

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Nanobased Platforms for Diagnosis and Treatment of COVID-19: From Benchtop to Bedside

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Diltiazem inhibits SARS-CoV-2 cell attachment and internalization and decreases the viral infection in mouse lung

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Comparing the Cytokine Storms of COVID-19 and Pandemic Influenza

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SARS-CoV-2 cell entry and targeted antiviral development

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Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease

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Cancer Occurrence as the Upcoming Complications of COVID-19

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Host Kinase CSNK2 is a Target for Inhibition of Pathogenic SARS-like β-Coronaviruses

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Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2

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SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates

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The therapeutic potential of inorganic polyphosphate: A versatile physiological polymer to control coronavirus disease (COVID-19)

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Channels and Transporters of the Pulmonary Lamellar Body in Health and Disease

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Some natural compounds and their analogues having potent anti- SARS-CoV-2 and anti-proteases activities as lead molecules in drug discovery for COVID-19

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Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-Coronaviruses

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Veklury® (remdesivir) formulations inhibit initial membrane‐coupled events of SARS‐CoV‐2 infection due to their sulfobutylether‐β‐cyclodextrin content

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SARS-CoV-2 Receptors and Their Involvement in Cell Infection

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From Cell to Symptoms: The Role of SARS-CoV-2 Cytopathic Effects in the Pathogenesis of COVID-19 and Long COVID

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SARS-CoV-2 infects neurons, astrocytes, choroid plexus epithelial cells and pericytes of the human central nervous system in vitro

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Targeting autophagy regulation in NLRP3 inflammasome-mediated lung inflammation in COVID-19

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The FDA-approved drug Auranofin has a dual inhibitory effect on SARS-CoV-2 entry and NF-κB signaling

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A pseudovirus-based platform to measure neutralizing antibodies in Mexico using SARS-CoV-2 as proof-of-concept

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Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2

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Factor V Has Anticoagulant Activity in Plasma in the Presence of TFPIα: Difference between FV1 and FV2

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Potential COVID‐19 therapeutic approaches targeting angiotensin‐converting enzyme 2; An updated review

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Cytoplasmic domain and enzymatic activity of ACE2 are not required for PI4KB dependent endocytosis entry of SARS-CoV-2 into host cells

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Targeted escape of SARS-CoV-2 in vitro from monoclonal antibody S309, the precursor of sotrovimab

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Immune interaction between SARS-CoV-2 and Mycobacterium tuberculosis

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Roles of the ACE/Ang II/AT1R pathway, cytokine release, and alteration of tight junctions in COVID-19 pathogenesis

Ashour, L. (2022) · Tissue Barriers · doi:10.1080/21688370.2022.2090792 · Cited by 22

Cell and Animal Models for SARS-CoV-2 Research

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Small GTPase—A Key Role in Host Cell for Coronavirus Infection and a Potential Target for Coronavirus Vaccine Adjuvant Discovery

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Single particle tracking reveals SARS-CoV-2 regulating and utilizing dynamic filopodia for viral invasion

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Regulated Intramembrane Proteolysis of ACE2: A Potential Mechanism Contributing to COVID-19 Pathogenesis?

González, S. M., Siddik, A. B., & Su, R. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.612807 · Cited by 23

COVID-19: Sleep, Circadian Rhythms and Immunity – Repurposing Drugs and Chronotherapeutics for SARS-CoV-2

Giri, A., Srinivasan, A., & Sundar, I. K. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.674204 · Cited by 23

ACE2 interaction with cytoplasmic PDZ protein enhances SARS-CoV-2 invasion

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Baricitinib attenuates the proinflammatory phase of COVID-19 driven by lung-infiltrating monocytes

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SARS-CoV-2 entry and fusion are independent of ACE2 localization to lipid rafts

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Involvement of adaptor proteins in clathrin-mediated endocytosis of virus entry

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Endothelial inflammation and dysfunction in COVID-19

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The Endolysosomal System: The Acid Test for SARS-CoV-2

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Umbelliferone and eriodictyol suppress the cellular entry of SARS-CoV-2

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P21-activated kinase 1 (PAK1)-mediated cytoskeleton rearrangement promotes SARS-CoV-2 entry and ACE2 autophagic degradation

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Viral Interactions with Adaptor-Protein Complexes: A Ubiquitous Trait among Viral Species

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A spatial multi-scale fluorescence microscopy toolbox discloses entry checkpoints of SARS-CoV-2 variants in Vero E6 cells

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Adrenal Gland Function and Dysfunction During COVID-19

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Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections

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SARS-CoV-2 S1 Protein Induces Endolysosome Dysfunction and Neuritic Dystrophy

Datta, G., Miller, N., Halcrow, P. W., Khan, N., Colwell, T., Geiger, J. D., & Chen, X. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.777738 · Cited by 21

ACE2 internalization induced by a SARS-CoV-2 recombinant protein is modulated by angiotensin II type 1 and bradykinin 2 receptors

Portales, A. E., Mustafá, E. R., McCarthy, C. I., Cornejo, M. P., Couto, P. M., Gironacci, M. M., Caramelo, J. J., Perelló, M., & Raingo, J. (2022) · Life Sciences · doi:10.1016/j.lfs.2021.120284 · Cited by 18

Counter-regulatory renin-angiotensin system in hypertension: review and update in the era of COVID-19 pandemic

Chen, H., Peng, J., Wang, T., Wen, J., Chen, S., Huang, Y., & Zhang, Y. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.115370 · Cited by 19

Salicylanilides Reduce SARS-CoV-2 Replication and Suppress Induction of Inflammatory Cytokines in a Rodent Model

Blake, S., Shaabani, N., Eubanks, L. M., Maruyama, J., Manning, J. T., Beutler, N., Paessler, S., Ji, H., Teijaro, J. R., & Janda, K. D. (2021) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.1c00253 · Cited by 21

Effect of Clinically Used Microtubule Targeting Drugs on Viral Infection and Transport Function

Oliva, M. A., Tosat‐Bitrián, C., Barrado-Gil, L., Bonato, F., Galindo, I., Garaigorta, U., Álvarez‐Bernad, B., París-Ogáyar, R., Lucena‐Agell, D., Giménez-Abián, J. F., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073448 · Cited by 18

Repurposing clinically available drugs and therapies for pathogenic targets to combat SARS‐CoV‐2

Xue, Y., Mei, H., Chen, Y., Griffin, J. D., Liu, Q., Weisberg, E., & Yang, J. C. (2023) · MedComm · doi:10.1002/mco2.254 · Cited by 20

Endosomal fusion of pH-dependent enveloped viruses requires ion channel TRPM7

Doyle, C. A., Busey, G. W., Iobst, W. H., Kiessling, V., Renken, C., Doppalapudi, H., Stremska, M. E., Manjegowda, M. C., Arish, M., Wang, W., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-52773-w · Cited by 21

RNA m5C methylation modification: a potential therapeutic target for SARS-CoV-2-associated myocarditis

Xiong, Y., Li, Y., Qian, W.-W., & Zhang, Q. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1380697 · Cited by 17

Porcine Deltacoronavirus (PDCoV) Entry into PK-15 Cells by Caveolae-Mediated Endocytosis

Li, S., Xiao, D., Zhao, Y., Zhang, L., Chen, R., Liu, W., Wen, Y., Liao, Y., Wen, Y., Wu, R. J., et al. (2022) · Viruses · doi:10.3390/v14030496 · Cited by 18

Myocardial Injury and Altered Gene Expression Associated With SARS-CoV-2 Infection or mRNA Vaccination

Altman, N. L., Berning, A. A., Saxon, C. E., Adamek, K. E., Wagner, J. A., Slavov, D. B., Quaife, R. A., Gill, E. A., Minobe, W. A., Jonas, E. R., et al. (2022) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2022.08.005 · Cited by 20

Single-nucleus transcriptomic profiling of multiple organs in a rhesus macaque model of SARS-CoV-2 infection

Ma, Q., 中国科学院生物物理研究所脑与认知科学国家重点实验室, 北., Ma, W., Song, T., Wu, Z., Liu, Z., Hu, Z., Han, J.-B., Xu, L., Zeng, B., et al. (2022) · 动物学研究 · doi:10.24272/j.issn.2095-8137.2022.443 · Cited by 18

SARS‐CoV‐2, periodontal pathogens, and host factors: The trinity of oral post‐acute sequelae of COVID‐19

SCHWARTZ, J. L., Capistrano, K. J., Gluck, J., Hezarkhani, A., & Naqvi, A. R. (2024) · Reviews in Medical Virology · doi:10.1002/rmv.2543 · Cited by 20

COVID-19: from immune response to clinical intervention

Guo, Z.-Y., Tang, Y., Zhang, Z.-B., Liu, J., Zhuang, Y., & Li, T. (2024) · Precision Clinical Medicine · doi:10.1093/pcmedi/pbae015 · Cited by 18

Type 2 Diabetes Contributes to Altered Adaptive Immune Responses and Vascular Inflammation in Patients With SARS-CoV-2 Infection

Singh, M., Adame, O. B., Nickas, M., Robison, J., Khatchadourian, C., & Venketaraman, V. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.833355 · Cited by 19

Chlorpromazine, a Clinically Approved Drug, Inhibits SARS-CoV-2 Nucleocapsid-Mediated Induction of IL-6 in Human Monocytes

Karwaciak, I., Karaś, K., Sałkowska, A., Pastwińska, J., & Ratajewski, M. (2022) · Molecules · doi:10.3390/molecules27123651 · Cited by 15

SARS-CoV-2 Spike-Mediated Entry and Its Regulation by Host Innate Immunity

Yu, S., Hu, H., Ai, Q., Bai, R., Ma, K., Zhou, M., & Wang, S. (2023) · Viruses · doi:10.3390/v15030639 · Cited by 20

Identification of diphenylurea derivatives as novel endocytosis inhibitors that demonstrate broad-spectrum activity against SARS-CoV-2 and influenza A virus both in vitro and in vivo

Kumar, N., Taily, I. M., Singh, C., Kumar, S., Rajmani, R. S., Chakraborty, D., Sharma, A., Singh, P., Thakur, K. G., Varadarajan, R., et al. (2023) · PLoS Pathogens · doi:10.1371/journal.ppat.1011358 · Cited by 17

Newcastle disease virus activates diverse signaling pathways via Src to facilitate virus entry into host macrophages

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Cholesterol and COVID-19—therapeutic opportunities at the host/virus interface during cell entry

Grewal, T., Nguyen, M. K. L., & Buechler, C. (2024) · Life Science Alliance · doi:10.26508/lsa.202302453 · Cited by 17

Unveiling the Dynamic Mechanism of SARS-CoV-2 Entry Host Cells at the Single-Particle Level

Li, S., Yang, H., Tian, F., Li, W., Wang, H., Shi, X., Cui, Z., & Shan, Y. (2024) · ACS Nano · doi:10.1021/acsnano.4c04212 · Cited by 15

Immunomodulation of COVID‐19 severity by helminth co‐infection: Implications for COVID‐19 vaccine efficacy

Akelew, Y., Henok, A., Ebrahim, E., Atnaf, A., & Hailemichael, W. (2021) · Immunity Inflammation and Disease · doi:10.1002/iid3.573 · Cited by 17

Low-Dose Fluvoxamine Modulates Endocytic Trafficking of SARS-CoV-2 Spike Protein: A Potential Mechanism for Anti-COVID-19 Protection by Antidepressants

Glebov, O. O. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.787261 · Cited by 15

Mechanistic-Based Classification of Endocytosis-Related Inhibitors: Does It Aid in Assigning Drugs against SARS-CoV-2?

Hessien, M., Donia, T., Tabll, A. A., Adly, E. M., Abdelhafez, T. H., Attia, A., Alkafaas, S. S., Kuna, L., Glasnović, M., Ćosić, V., et al. (2023) · Viruses · doi:10.3390/v15051040 · Cited by 16

TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution

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