SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis

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Hesperetin and the PI3K/AKT pathway: Could their interaction play a role in the entry and replication of the SARS‐CoV‐2?

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Cathepsins in cellular entry of human pathogenic viruses

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Cellular and Molecular Mechanisms of In Vivo and In Vitro SARS-CoV-2 Infection: A Lesson from Human Sperm

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Overcoming antibody-resistant SARS-CoV-2 variants with bispecific antibodies constructed using non-neutralizing antibodies

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Smoking and vaping alter genes related to mechanisms of SARS-CoV-2 susceptibility and severity: a systematic review and meta-analysis

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Influence of Th1 versus Th2 immune bias on viral, pathological, and immunological dynamics in SARS-CoV-2 variant-infected human ACE2 knock-in mice

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Fish Paralog Proteins RNASEK-a and -b Enhance Type I Interferon Secretion and Promote Apoptosis

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Autophagy in severe acute respiratory syndrome coronavirus 2 infection

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Potential of Endogenous Oxytocin in Endocrine Treatment and Prevention of COVID-19

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Uptake of severe acute respiratory syndrome coronavirus 2 spike protein mediated by angiotensin converting enzyme 2 and ganglioside in human cerebrovascular cells

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A systematic review on impact of SARS-CoV-2 infection

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Viral uptake and pathophysiology of the lung endothelial cells in age‐associated severe SARS‐CoV ‐2 infection models

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SARS-CoV-2 Assembly: Gaining Infectivity and Beyond

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Next-generation small molecule inhibitors of clathrin function acutely inhibit endocytosis

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Docosahexaenoic acid-containing phosphatidic acid interacts with clathrin coat assembly protein AP180 and regulates its interaction with clathrin

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DeepHVI: A multimodal deep learning framework for predicting human-virus protein-protein interactions using protein language models

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The New SARS-CoV-2 Variants and Their Epidemiological Impact in Mexico

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Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission

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Harnessing traditional Chinese medicine polysaccharides for combatting COVID-19

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In Silico Discovery and Evaluation of Inhibitors of the SARS-CoV-2 Spike Protein–HSPA8 Complex Towards Developing COVID-19 Therapeutic Drugs

Navhaya, L. T., Matsebatlela, T. M., Monama, M. Z., & Makhoba, X. H. (2024) · Viruses · doi:10.3390/v16111726 · Cited by 10

Noncommunicable diseases risk factors and the risk of COVID-19 among university employees in Indonesia

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Baricitinib as the treatment of choice for hospitalised individuals with COVID-19

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COVID-19 and diarrhea: putative mechanisms and management

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SARS-CoV-2 spike-glycoprotein processing at S1/S2 and S2’and shedding of the ACE2 viral receptor: roles of Furin and TMPRSS2 and implications for viral infectivity and cell-to-cell fusionPreprint

Essalmani, R., Jain, J., Susan‐Resiga, D., Andréo, U., Evagelidis, A., Derbali, R. M., Huynh, D. N., Dallaire, F., Laporte, M., Delpal, A., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.18.423106 · Cited by 11

SARS-CoV-2 Spike Protein Stimulates Macropinocytosis in Murine and Human Macrophages via PKC-NADPH Oxidase Signaling

Ahn, W., Burnett, F. N., Pandey, A., Ghoshal, P., Singla, B., Simon, A. B., Derella, C. C., Addo, S. A., Harris, R. A., Lucas, R., et al. (2024) · Antioxidants · doi:10.3390/antiox13020175 · Cited by 9

SARS-CoV-2 Membrane protein regulates the function of Spike by inhibiting its plasma membrane localization and enzymatic activity of Furin

Xiang, Q., Wu, J., Zhou, Y., Li, L., Tian, M., Li, G., Zhang, Z., & Fu, Y. (2024) · Microbiological Research · doi:10.1016/j.micres.2024.127659 · Cited by 9

Discovery of a novel inhibitor of macropinocytosis with antiviral activity

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Computational Evidence for Bisartan Arginine Blockers as Next-Generation Pan-Antiviral Therapeutics Targeting SARS-CoV-2, Influenza, and Respiratory Syncytial Viruses

Ridgway, H. F., Apostolopoulos, V., Moore, G. J., Gadanec, L. K., Zulli, A., Swiderski, J., Tsiodras, S., Kelaidonis, K., Chasapis, C. T., & Matsoukas, J. (2024) · Viruses · doi:10.3390/v16111776 · Cited by 9

A systemic review on liquid crystals, nanoformulations and its application for detection and treatment of SARS – CoV- 2 (COVID – 19)

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Computational design of candidate multi-epitope vaccine against SARS-CoV-2 targeting structural (S and N) and non-structural (NSP3 and NSP12) proteins

Ali, Z., Cardoza, J. V., Basak, S., Narsaria, U., Singh, V. P., Isaac, S. P., França, T. C. C., LaPlante, S. R., & george, S. S. (2023) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2023.2173297 · Cited by 9

Altered microRNA Transcriptome in Cultured Human Airway Cells upon Infection with SARS-CoV-2

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Use of Antiandrogens as Therapeutic Agents in COVID-19 Patients

Giotis, E. S., Cil, E., & Brooke, G. N. (2022) · Viruses · doi:10.3390/v14122728 · Cited by 8

Effect of SARS-CoV-2 infection in pregnancy on CD147, ACE2 and HLA-G expression

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Therapeutic development targeting host heparan sulfate proteoglycan in SARS-CoV-2 infection

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A Structural Voyage Toward the Landscape of Humoral and Cellular Immune Escapes of SARS ‐ CoV ‐2

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Spike mutations that affect the function and antigenicity of recent KP.3.1.1-like SARS-CoV-2 variants

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Targeting clathrin-mediated endocytosis: recent advances in inhibitor development, mechanistic insights, and therapeutic prospects

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Potential use of renin-angiotensin-aldosterone system inhibitors to reduce COVID-19 severity

Gonçalves, J., Santos, C. D., Fresco, P., & Fernández-Llimós, F. (2023) · Revista Portuguesa de Cardiologia · doi:10.1016/j.repc.2022.02.014 · Cited by 8

More than a key—the pathological roles of SARS-CoV-2 spike protein in COVID-19 related cardiac injury

Lin, Z. (2023) · Sports Medicine and Health Science · doi:10.1016/j.smhs.2023.03.004 · Cited by 8

The Local Anaesthetic Procaine Prodrugs ProcCluster® and Procaine Hydrochloride Impair SARS-CoV-2 Replication and Egress In Vitro

Häring, C., Jungwirth, J., Schroeder, J., Löffler, B., Engert, B., & Ehrhardt, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241914584 · Cited by 8

The Two Sides of the COVID-19 Pandemic

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Revealing the Cell Entry Dynamic Mechanism of Single Rabies Virus Particle

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Analysis of cell–nanoparticle interactions and imaging of in vitro labeled cells showing barcorded endosomes using fluorescent thiol-organosilica nanoparticles surface-functionalized with polyethyleneimine

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Virus-Like Particles of SARS-CoV-2 as Virus Surrogates: Morphology, Immunogenicity, and Internalization in Neuronal Cells

Kumar, C. S., Singh, B., Rizvi, Z. A., Parray, H. A., Verma, J. K., Ghosh, S., Mukhopadhyay, A., Awasthi, A., Shrivastava, T., & Banerjee, M. (2022) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.2c00217 · Cited by 8

Modulation of Paracellular Permeability in SARS-CoV-2 Blood-to-Brain Transcytosis

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Potential Effects of Hyperglycemia on SARS-CoV-2 Entry Mechanisms in Pancreatic Beta Cells

Michaels, T. M., Essop, M. F., & Joseph, D. E. (2024) · Viruses · doi:10.3390/v16081243 · Cited by 12

The inactivation of the Niemann Pick C1 cholesterol transporter restricts SARS-CoV-2 entry into host cells by decreasing ACE2 abundance at the plasma membrane

Rosa, P. L., Tiberi, J., Palermo, E., Stefanelli, R., Tiano, S. M. L., Canterini, S., Cortese, M., Hiscott, J. B., & Fiorenza, M. T. (2024) · Cell & Bioscience · doi:10.1186/s13578-024-01331-4 · Cited by 7

From zoonotic spillover to endemicity: the broad determinants of human coronavirus tropism

Westhoven, S., Bertzbach, L. D., Kloehn, M., Mahncke, C., Heinen, N., Brown, R. J. P., & Pfaender, S. (2025) · mBio · doi:10.1128/mbio.02437-25 · Cited by 9

Bat sarbecovirus WIV1-CoV bears an adaptive mutation that alters spike dynamics and enhances ACE2 binding

Tse, A. L., Lasso, G., Berrigan, J. L., McLellan, J. S., Chandran, K., & Miller, E. H. (2025) · PLoS Pathogens · doi:10.1371/journal.ppat.1013123 · Cited by 7

Coronaviruses, Lysosomes, and Secondary Bacterial Infections: Coronaviruses Outsmart the Host

Peng, X., Cruz, C. S. D., & Sharma, L. (2023) · DNA and Cell Biology · doi:10.1089/dna.2023.0002 · Cited by 7

Role of VPS39, a key tethering protein for endolysosomal trafficking and mitochondria–lysosome crosstalk, in health and disease

Li, H., Gong, W., Sun, W., Yao, Y., & Han, Y. (2023) · Journal of Cellular Biochemistry · doi:10.1002/jcb.30396 · Cited by 7

Verifying AXL and putative proteins as SARS‐CoV‐2 receptors by DnaE intein‐based rapid cell–cell fusion assay

Fang, Q., He, X., Zheng, X., Fu, Y., Fu, T., Luo, J., Du, Y., Lan, J., Yang, J., Luo, Y., et al. (2023) · Journal of Medical Virology · doi:10.1002/jmv.28953 · Cited by 9

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein

Tang, X., Liu, Y., Wang, J., Long, T., Mok, B. W.-Y., Huang, Y., Peng, Z., Jia, Q., Liu, C., So, P., et al. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.107390 · Cited by 7

SARS-CoV-2 nucleocapsid protein promotes self-deacetylation by inducing HDAC6 to facilitate viral replication

Mukherjee, A., Lo, M., Chandra, P., Chaudhuri, R. D., De, P., Dutta, S., & Chawla‐Sarkar, M. (2024) · Virology Journal · doi:10.1186/s12985-024-02460-5 · Cited by 7

Acidic pH of early endosomes governs SARS-CoV-2 transport in host cells

Fares, P., Duhaini, M., Tripathy, S. K., Srour, A., & Kondapalli, K. C. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.108144 · Cited by 7

Characterization of a Novel SARS-CoV-2 Genetic Variant with Distinct Spike Protein Mutations

Gladkikh, A. S., Dolgova, A. S., Dedkov, V. G., Sbarzaglia, V. A., Kanaeva, O. I., Popova, A. Y., & Тотолян, А. А. (2021) · Viruses · doi:10.3390/v13061029 · Cited by 7

Hyperlipidemia and Obesity’s Role in Immune Dysregulation Underlying the Severity of COVID-19 Infection

Khatchadourian, C., Sisliyan, C., Nguyen, K., Poladian, N., Tian, Q., Tamjidi, F., Luong, B., Singh, M., Robison, J., & Venketaraman, V. (2021) · Clinics and Practice · doi:10.3390/clinpract11040085 · Cited by 9

Kite-Shaped Molecules Block SARS-CoV-2 Cell Entry at a Post-Attachment Step

Chan, S., Shafi, T., & Ford, R. C. (2021) · Viruses · doi:10.3390/v13112306 · Cited by 7

COVID-19 Worsens Chronic Lumbosacral Radicular Pain—Case Series Report

Illéš, R., Chochol, J., Džubera, A., Chocholová, A., & Zemková, E. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19116410 · Cited by 6

Imaging Techniques: Essential Tools for the Study of SARS-CoV-2 Infection

Deroubaix, A., & Kramvis, A. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.794264 · Cited by 7

Biomechanical Role of Epsin in Influenza A Virus Entry

Joseph, J. G., Mudgal, R. K., Lin, S., Ono, A., & Liu, A. P. (2022) · Membranes · doi:10.3390/membranes12090859 · Cited by 7

COVID-19 Plasma Extracellular Vesicles Increase the Density of Lipid Rafts in Human Small Airway Epithelial Cells

Darwish, S., Liu, L., Robinson, T. O., Tarugu, S., Owings, A. H., Glover, S. C., & Alli, A. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24021654 · Cited by 7

Pathophysiological Aspects of COVID-19-Associated Vasculopathic Diseases

Greistorfer, T., & Jud, P. (2023) · Thrombosis and Haemostasis · doi:10.1055/s-0043-1768969 · Cited by 7

Light-dependent inhibition of clathrin-mediated endocytosis in yeast unveils conserved functions of the AP2 complex

Prischich, D., Camarero, N., del Dedo, J. E., Cambra-Pellejà, M., Prat, J., Nevola, L., Martín‐Quirós, A., Rebollo, E., Pastor, L., Giralt, E., et al. (2023) · iScience · doi:10.1016/j.isci.2023.107899 · Cited by 7

Infection of liver sinusoidal endothelial cells with Muromegalovirus muridbeta1 involves binding to neuropilin-1 and is dynamin-dependent

Kyrrestad, I., Larsen, A. K., Romano, J. S., Simón-Santamaría, J., Li, R., & Sørensen, K. K. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1249894 · Cited by 8

Validation of nuclear receptor RORγ isoform 1 as a novel host-directed antiviral target based on the modulation of cholesterol levels

Wangen, C., Raithel, A., Tillmanns, J., Gege, C., Herrmann, A., Vitt, D., Kohlhof, H., Marschall, M., & Hahn, F. (2023) · Antiviral Research · doi:10.1016/j.antiviral.2023.105769 · Cited by 7

Potential effects of icariin, the Epimedium-derived bioactive compound in the treatment of COVID‐19: a hypothesis

Khezri, M. R., Nazari‐Khanamiri, F., Mohammadi, T., Moloodsouri, D., & Ghasemnejad‐Berenji, M. (2022) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-022-02262-y · Cited by 7

Neuromasts and Olfactory Organs of Zebrafish Larvae Represent Possible Sites of SARS-CoV-2 Pseudovirus Host Cell Entry

Choi, S. S. A., Chan, H. H., Chan, C. M., Wang, X., Webb, S., Leung, K. W., Tsim, K. W. K., & Miller, A. L. (2022) · Journal of Virology · doi:10.1128/jvi.01418-22 · Cited by 7

Human Coronavirus 229E Uses Clathrin-Mediated Endocytosis as a Route of Entry in Huh-7 Cells

Andreu, S., Ripa, I., López‐Guerrero, J. A., & Bello‐Morales, R. (2024) · Biomolecules · doi:10.3390/biom14101232 · Cited by 6

Understanding the neurological implications of acute and long COVID using brain organoids

García‐González, L., Martí-Sarrias, A., Puertas, M. C., Bayón-Gil, Á., Resa‐Infante, P., Martínez‐Picado, J., Navarro, A., & Acosta, S. (2023) · Disease Models & Mechanisms · doi:10.1242/dmm.050049 · Cited by 7

SARS-CoV-2 spike receptor-binding domain is internalized and promotes protein ISGylation in human induced pluripotent stem cell-derived cardiomyocytes

Okuno, S., Higo, S., Kondo, T., Shiba, M., Kameda, S., Inoue, H., Tabata, T., Ogawa, S., Morishita, Y., Sun, C., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-48084-7 · Cited by 6

Pseudorabies virus uses clathrin mediated endocytosis to enter PK15 swine cell line

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