Cognitive behavioral therapy versus paroxetine in the treatment of hypochondriasis: an 18-month naturalistic follow-up
Abstract
Background The present maintenance study investigated whether the reduction in hypochondriacal complaints after initial treatment with CBT or paroxetine sustained during a follow-up period and whether psychiatric severity at pretest predicted the course of hypochondriacal symptoms.Method A naturalistic follow-up period of 18 months after a 16-week RCT consisting of 33 patients initially allocated to a CBT condition and 29 patients to a paroxetine condition. The main outcome measure was the Whiteley Index.Results The initial treatment effect of CBT and paroxetine sustained during the follow-up period. No significant differences between CBT and paroxetine were found. Treatment course could not be predicted by psychiatric comorbidity.Conclusion CBT and paroxetine are both effective treatments for hypochondriasis in the long term.
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In the larger study (Greeven 2007), improvement persisted to 18 months.
“and this improvement persisted to 18 months (Greeven 2009).”
From Health anxiety: Detection and treatment (2018) · cites this paper as Greeven 2009
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- Authors
- Greeven, A., van Balkom, A. J. L. M., van der Leeden, R., Merkelbach, J. W., van den Heuvel, O. A., & Spinhoven, P.
- Affiliations
- Leiden University (NL)
- Leiden University Medical Center (NL)
- Corresponding author
- Greeven, Anja
- ORCID
- Spinhoven, Philip
- Venue
- Journal of Behavior Therapy and Experimental Psychiatry
- Publisher
- Elsevier BV
- Published
- 2009-09
- Volume
- 40
- Issue
- 3
- Pages
- 487-496
- ISSN
- 0005-7916 (ISSN-L)
- OpenAlex
- W1980358513
- Cited by
- 55
- References
- 24
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 3 · 2022: 1 · 2021: 5 · 2020: 3 · 2019: 3 · 2018: 2 · 2017: 3 · 2016: 2 · 2015: 4 · 2014: 9 · 2013: 4 · 2012: 4
- FWCI
- 2.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Behavior Therapy and Experimental Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
- Keywords
- health anxiety, cognitive behavioral therapy, paroxetine, long-term treatment outcomes, maintenance of treatment effects, psychiatric comorbidity, Whiteley Index, naturalistic follow-up
- MeSH terms
- Adult, Double-Blind Method, Drug Administration Schedule, Female, Follow-Up Studies, Humans, Hypochondriasis, Male, Middle Aged, Psychiatric Status Rating Scales, Severity of Illness Index, Cognitive Behavioral Therapy, Chi-Square Distribution, Selective Serotonin Reuptake Inhibitors, Paroxetine
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