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Cited by 294

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Effect of Intravascular Ultrasound–Guided Drug-Eluting Stent Implantation

Open access
Hong, Sung-Jin, Mintz, Gary S., Ahn, Chul-Min, Kim, Jung-Sun, Kim, Byeong-Keuk, Ko, Young-Guk, Kang, Tae-Soo, Kang, Woong-Chol, Kim, Yong Hoon, Hur, Seung-Ho, Hong, Bum-Kee, Choi, Donghoon, Kwon, Hyuckmoon, Jang, Yangsoo, Hong, Myeong-Ki·2020·JACC: Cardiovascular Interventions
DOI 10.1016/j.jcin.2019.09.033
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Abstract

OBJECTIVES The goal of this study was to evaluate whether the beneficial effect of use of intravascular ultrasound (IVUS) is sustained for long-term follow-up. BACKGROUND The use of IVUS promoted favorable 1-year clinical outcome in the IVUS-XPL (Impact of Intravascular Ultrasound Guidance on the Outcomes of Xience Prime Stents in Long Lesions) trial. It is not known, however, whether this effect is sustained for long-term follow-up. METHODS The IVUS-XPL trial randomized 1,400 patients with long coronary lesions (implanted stent length ≥28 mm) to receive IVUS-guided (n = 700) or angiography-guided (n = 700) everolimus-eluting stent implantation. Five-year clinical outcomes were investigated in patients who completed the original trial. The primary outcome was the composite of major adverse cardiac events, including cardiac death, target lesion-related myocardial infarction, or ischemia-driven target lesion revascularization at 5 years, analyzed by intention-to-treat. RESULTS Five-year follow-up was completed in 1,183 patients (85%). Major adverse cardiac events at 5 years occurred in 36 patients (5.6%) receiving IVUS guidance and in 70 patients (10.7%) receiving angiographic guidance (hazard ratio: 0.50; 95% confidence interval: 0.34 to 0.75; p = 0.001). The difference was driven mainly by a lower risk for target lesion revascularization (31 [4.8%] vs. 55 [8.4%]; hazard ratio: 0.54; 95% confidence interval: 0.33 to 0.89; p = 0.007). By landmark analysis, major adverse cardiac events between 1 and 5 years occurred in 17 patients (2.8%) receiving IVUS guidance and in 31 patients (5.2%) receiving angiographic guidance (hazard ratio: 0.53; 95% confidence interval: 0.29 to 0.95; p = 0.031). CONCLUSIONS Compared with angiography-guided stent implantation, IVUS-guided stent implantation resulted in a significantly lower rate of major adverse cardiac events up to 5 years. Sustained 5-year clinical benefits resulted from both within 1 year and from 1 to 5 years post-implantation. (Impact of Intravascular Ultrasound Guidance on the Outcomes of Xience Prime Stents in Long Lesions [IVUS-XPL Study]: Retrospective and Prospective Follow-Up Study; NCT03866486).

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Metadata

Authors
Hong, S.-J., Mintz, G. S., Ahn, C.-M., Kim, J.-S., Kim, B.-K., Ko, Y.-G., Kang, T.-S., Kang, W.-C., Kim, Y. H., Hur, S.-H., Hong, B.-K., Choi, D., Kwon, H., Jang, Y., & Hong, M.-K.
Venue
JACC: Cardiovascular Interventions
Publisher
Elsevier BV
Published
2020-01
Volume
13
Issue
1
Pages
62-71
ISSN
  • 1876-7605 (ISSN-L)
  • 1936-8798
DOI
10.1016/j.jcin.2019.09.033
OpenAlex
W2977637682
Cited by
294
References
10
FWCI
29.57
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Effect of Intravascular Ultrasound–Guided Drug-Eluting Stent Implantation. https://app.cochat.ai/papers/10.1016/j.jcin.2019.09.033
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Hong, S.-J., Mintz, G. S., Ahn, C.-M., Kim, J.-S., Kim, B.-K., Ko, Y.-G., Kang, T.-S., Kang, W.-C., Kim, Y. H., Hur, S.-H., Hong, B.-K., Choi, D., Kwon, H., Jang, Y., & Hong, M.-K. (2020). Effect of Intravascular Ultrasound–Guided Drug-Eluting Stent Implantation. JACC: Cardiovascular Interventions. https://doi.org/10.1016/j.jcin.2019.09.033

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