The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
OCT or Angiography Guidance for PCI in Complex Bifurcation Lesions
Open accessAbstract
BACKGROUND: Imaging-guided percutaneous coronary intervention (PCI) is associated with better clinical outcomes than angiography-guided PCI. Whether routine optical coherence tomography (OCT) guidance in PCI of lesions involving coronary-artery branch points (bifurcations) improves clinical outcomes as compared with angiographic guidance is uncertain. METHODS: We conducted a multicenter, randomized, open-label trial at 38 centers in Europe. Patients with a clinical indication for PCI and a complex bifurcation lesion identified by means of coronary angiography were randomly assigned in a 1:1 ratio to OCT-guided PCI or angiography-guided PCI. The primary end point was a composite of major adverse cardiac events (MACE), defined as death from a cardiac cause, target-lesion myocardial infarction, or ischemia-driven target-lesion revascularization at a median follow-up of 2 years. RESULTS: We assigned 1201 patients to OCT-guided PCI (600 patients) or angiography-guided PCI (601 patients). A total of 111 patients (18.5%) in the OCT-guided PCI group and 116 (19.3%) in the angiography-guided PCI group had a bifurcation lesion involving the left main coronary artery. At 2 years, a primary end-point event had occurred in 59 patients (10.1%) in the OCT-guided PCI group and in 83 patients (14.1%) in the angiography-guided PCI group (hazard ratio, 0.70; 95% confidence interval, 0.50 to 0.98; P = 0.035). Procedure-related complications occurred in 41 patients (6.8%) in the OCT-guided PCI group and 34 patients (5.7%) in the angiography-guided PCI group. CONCLUSIONS: Among patients with complex coronary-artery bifurcation lesions, OCT-guided PCI was associated with a lower incidence of MACE at 2 years than angiography-guided PCI. (Funded by Abbott Vascular and others; OCTOBER ClinicalTrials.gov number, NCT03171311.).
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2018 ESC/EACTS guidelines on myocardial revascularization
Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehy394 · Cited by 7,167
Self-citationTearney, G. J., Regar, E., Akasaka, T., Adriaenssens, T., Barlis, P., Bezerra, H. G., Bouma, B., Bruining, N., Cho, J.-M., Chowdhary, S., et al. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.09.079 · Cited by 1,874
Self-citationIntravascular Ultrasound Versus Angiography-Guided Drug-Eluting Stent Implantation
Zhang, J., Gao, X., Kan, J., Ge, Z., Han, L., Lu, S., Tian, N., Lin, S., Lu, Q., Wu, X., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.09.013 · Cited by 665
Intravascular Imaging–Guided or Angiography-Guided Complex PCI
Lee, J. M., Choi, K. H., Song, Y. B., Lee, J.-Y., Lee, S.-J., Lee, S. Y., Kim, S. M., Yun, K. H., Cho, J. Y., Kim, C. J., et al. (2023) · New England Journal of Medicine · doi:10.1056/nejmoa2216607 · Cited by 572
Optical coherence tomography in coronary atherosclerosis assessment and intervention
Araki, M., Park, S.-J., Dauerman, H. L., Uemura, S., Kim, J.-S., Di Mario, C., Johnson, T. W., Guagliumi, G., Kastrati, A., Joner, M., et al. (2022) · Nature Reviews Cardiology · doi:10.1038/s41569-022-00687-9 · Cited by 430
Self-citationClinical Impact of OCT Findings During PCI
Prati, F., Romagnoli, E., Burzotta, F., Limbruno, U., Gatto, L., La Manna, A., Versaci, F., Marco, V., Di Vito, L., Imola, F., et al. (2015) · JACC: Cardiovascular Imaging · doi:10.1016/j.jcmg.2015.08.013 · Cited by 360
Self-citationGao, X.-F., Ge, Z., Kong, X.-Q., Kan, J., Han, L., Lu, S., Tian, N.-L., Lin, S., Lu, Q.-H., Wang, X.-Y., et al. (2021) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2020.10.001 · Cited by 338
Effect of Intravascular Ultrasound–Guided Drug-Eluting Stent Implantation
Hong, S.-J., Mintz, G. S., Ahn, C.-M., Kim, J.-S., Kim, B.-K., Ko, Y.-G., Kang, T.-S., Kang, W.-C., Kim, Y. H., Hur, S.-H., et al. (2020) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2019.09.033 · Cited by 294
Kubo, T., Shinke, T., Okamura, T., Hibi, K., Nakazawa, G., Morino, Y., Shite, J., Fusazaki, T., Otake, H., Kozuma, K., et al. (2017) · European Heart Journal · doi:10.1093/eurheartj/ehx351 · Cited by 288
Lassen, J. F., Holm, N. R., Banning, A., Burzotta, F., Lefèvre, T., Chieffo, A., Hildick-Smith, D., Louvard, Y., & Stankovic, G. (2016) · EuroIntervention · doi:10.4244/eijv12i1a7 · Cited by 234
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2024 ESC Guidelines for the management of chronic coronary syndromes
Vrints, C., Andreotti, F., Koskinas, K. C., Rossello, X., Adamo, M., Ainslie, J., Banning, A. P., Budaj, A., Buechel, R. R., Chiariello, G. A., et al. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae177 · Cited by 2,774
Self-citationRao, S. V., O’Donoghue, M. L., Ruel, M., Rab, T., Tamis-Holland, J. E., Alexander, J. H., Baber, U., Baker, H., Cohen, M. G., Cruz-Ruiz, M., et al. (2025) · Circulation · doi:10.1161/cir.0000000000001309 · Cited by 625
Stone, G. W., Christiansen, E. H., Ali, Z. A., Andreasen, L. N., Maehara, A., Ahmad, Y., Landmesser, U., & Holm, N. R. (2024) · The Lancet · doi:10.1016/s0140-6736(23)02454-6 · Cited by 323
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Metadata
- Authors
- Holm, N. R., Andreasen, L. D., Neghabat, O., Laanmets, P., Kumsars, I., Bennett, J., Olsen, N. T., Odenstedt, J., Hoffmann, P., Dens, J., Chowdhary, S., O’Kane, P., Bülow Rasmussen, S.-H., Heigert, M., Havndrup, O., Van Kuijk, J. P., Biscaglia, S., Mogensen, L. J. H., Henareh, L., Burzotta, F., H. Eek, C., Mylotte, D., Llinas, M. S., Koltowski, L., Knaapen, P., Calic, S., Witt, N., Santos-Pardo, I., Watkins, S., Lønborg, J., Kristensen, A. T., Jensen, L. O., Calais, F., Cockburn, J., McNeice, A., Kajander, O. A., Heestermans, T., Kische, S., Eftekhari, A., Spratt, J. C., & Christiansen, E. H.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2023-10-19
- Volume
- 389
- Issue
- 16
- Pages
- 1477-1487
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4386206298
- Cited by
- 375
- References
- 16
- FWCI
- 89.44
- Type
- journal article
- Language
- en
- Open access
- green
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- Holm, N. R., Andreasen, L. D., Neghabat, O., Laanmets, P., Kumsars, I., Bennett, J., Olsen, N. T., Odenstedt, J., Hoffmann, P., Dens, J., Chowdhary, S., O’Kane, P., Bülow Rasmussen, S.-H., Heigert, M., Havndrup, O., Van Kuijk, J. P., Biscaglia, S., Mogensen, L. J. H., Henareh, L., . . . Christiansen, E. H. (2023). OCT or Angiography Guidance for PCI in Complex Bifurcation Lesions. New England Journal of Medicine. https://doi.org/10.1056/nejmoa2307770
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