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Cited by 665

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Intravascular Ultrasound Versus Angiography-Guided Drug-Eluting Stent Implantation

Open access
Zhang, Junjie, Gao, Xiaofei, Kan, Jing, Ge, Zhen, Han, Leng, Lu, Shu, Tian, Nailiang, Lin, Song, Lu, Qinghua, Wu, Xueming, Li, Qihua, Liu, Zhizhong, Chen, Yan, Qian, Xuesong, Wang, Juan, Chai, Dayang, Chen, Chonghao, Li, Xiaolong, Gogas, Bill D., Pan, Tao, Shan, Shoujie, Ye, Fei, Chen, Shao-Liang·2018·Journal of the American College of Cardiology
DOI 10.1016/j.jacc.2018.09.013
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Abstract

BACKGROUND Intravascular ultrasound (IVUS)-guided drug-eluting stent (DES) implantation is associated with fewer major adverse cardiovascular events compared with angiography guidance for patients with individual lesion subset. However, the beneficial effect on major adverse cardiovascular event outcome of IVUS guidance over angiography guidance in all-comers who undergo DES implantation still remains understudied. OBJECTIVES This study aimed to determine the benefits of IVUS guidance over angiography guidance during DES implantation in all-comer patients. METHODS A total of 1,448 all-comer patients who required DES implantation were randomly assigned (1:1 ratio) to either an IVUS guidance or angiography guidance group. The primary endpoint was target-vessel failure (TVF) at 12 months, including cardiac death, target-vessel myocardial infarction, and clinically driven target-vessel revascularization (TVR). The procedure was defined as a success if all IVUS-defined optimal criteria were met. RESULTS At 12 months follow-up, 60 TVFs (4.2%) occurred, with 21 (2.9%) in the IVUS group and 39 (5.4%) in the angiography group (hazard ratio [HR]: 0.530; 95% confidence interval [CI]: 0.312 to 0.901; p = 0.019). In the IVUS group, TVF was recorded in 1.6% of patients with successful procedures, compared with 4.4% in patients who failed to achieve all optimal criteria (HR: 0.349; 95% CI: 0.135 to 0.898; p = 0.029). The significant reduction of clinically driven target-lesion revascularization or definite stent thrombosis (HR: 0.407; 95% CI: 0.188 to 0.880; p = 0.018) based on lesion-level analysis by IVUS guidance was not achieved when the patient-level analysis was performed. CONCLUSIONS The present study demonstrates that IVUS-guided DES implantation significantly improved clinical outcome in all-comers, particularly for patients who had an IVUS-defined optimal procedure, compared with angiography guidance. (Intravascular Ultrasound Guided Drug Eluting Stents Implantation in "All-Comers" Coronary Lesions [ULTIMATE]; NCT02215915).

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Metadata

Authors
Zhang, J., Gao, X., Kan, J., Ge, Z., Han, L., Lu, S., Tian, N., Lin, S., Lu, Q., Wu, X., Li, Q., Liu, Z., Chen, Y., Qian, X., Wang, J., Chai, D., Chen, C., Li, X., Gogas, B. D., Pan, T., Shan, S., Ye, F., & Chen, S.-L.
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
2018-12
Volume
72
Issue
24
Pages
3126-3137
ISSN
0735-1097 (ISSN-L)
DOI
10.1016/j.jacc.2018.09.013
OpenAlex
W2899610111
Cited by
665
References
15
FWCI
46.89
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Intravascular Ultrasound Versus Angiography-Guided Drug-Eluting Stent Implantation. https://app.cochat.ai/papers/10.1016/j.jacc.2018.09.013
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Zhang, J., Gao, X., Kan, J., Ge, Z., Han, L., Lu, S., Tian, N., Lin, S., Lu, Q., Wu, X., Li, Q., Liu, Z., Chen, Y., Qian, X., Wang, J., Chai, D., Chen, C., Li, X., Gogas, B. D., . . . Chen, S.-L. (2018). Intravascular Ultrasound Versus Angiography-Guided Drug-Eluting Stent Implantation. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2018.09.013

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.