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Cited by 1,642

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Bacterial biofilm and associated infections

Open access
Jamal, Muhsin, Ahmad, Wisal, Andleeb, Saadia, Jalil, Fazal, Imran, Muhammad, Nawaz, Muhammad Asif, Hussain, Tahir, Ali, Muhammad, Rafiq, Muhammad, Kamil, Muhammad Atif·2018·Journal of the Chinese Medical Association
DOI 10.1016/j.jcma.2017.07.012
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Abstract

Microscopic entities, microorganisms that drastically affect human health need to be thoroughly investigated. A biofilm is an architectural colony of microorganisms, within a matrix of extracellular polymeric substance that they produce. Biofilm contains microbial cells adherent to one-another and to a static surface (living or non-living). Bacterial biofilms are usually pathogenic in nature and can cause nosocomial infections. The National Institutes of Health (NIH) revealed that among all microbial and chronic infections, 65% and 80%, respectively, are associated with biofilm formation. The process of biofilm formation consists of many steps, starting with attachment to a living or non-living surface that will lead to formation of micro-colony, giving rise to three-dimensional structures and ending up, after maturation, with detachment. During formation of biofilm several species of bacteria communicate with one another, employing quorum sensing. In general, bacterial biofilms show resistance against human immune system, as well as against antibiotics. Health related concerns speak loud due to the biofilm potential to cause diseases, utilizing both device-related and non-device-related infections. In summary, the understanding of bacterial biofilm is important to manage and/or to eradicate biofilm-related diseases. The current review is, therefore, an effort to encompass the current concepts in biofilm formation and its implications in human health and disease.

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Metadata

Authors
Jamal, M., Ahmad, W., Andleeb, S., Jalil, F., Imran, M., Nawaz, M. A., Hussain, T., Ali, M., Rafiq, M., & Kamil, M. A.
Venue
Journal of the Chinese Medical Association
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2018-01
Volume
81
Issue
1
Pages
7-11
ISSN
1726-4901 (ISSN-L)
DOI
10.1016/j.jcma.2017.07.012
OpenAlex
W2761783016
Cited by
1,642
References
45
FWCI
28.54
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Bacterial biofilm and associated infections. https://app.cochat.ai/papers/10.1016/j.jcma.2017.07.012
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Jamal, M., Ahmad, W., Andleeb, S., Jalil, F., Imran, M., Nawaz, M. A., Hussain, T., Ali, M., Rafiq, M., & Kamil, M. A. (2018). Bacterial biofilm and associated infections. Journal of the Chinese Medical Association. https://doi.org/10.1016/j.jcma.2017.07.012

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.