Doxil® — The first FDA-approved nano-drug: Lessons learned

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8. Doxorubicin liposome-loaded microbubbles for contrast imaging and ultrasound-triggered drug delivery
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9. Harnessing designed nanoparticles: Current strategies and future perspectives in cancer immunotherapy
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10. Enhanced cellular uptake and nuclear accumulation of drug-peptide nanomedicines prepared by enzyme-instructed self-assembly
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11. Gain an advantage from both sides: Smart size-shrinkable drug delivery nanosystems for high accumulation and deep penetration
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12. Bio-based nanomaterials for cancer therapy
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13. Engineered nanomaterials for biomedical applications and their toxicity: a review
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14. Quality by Design Approach in Liposomal Formulations: Robust Product Development
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15. Universal redirection of CAR T cells against solid tumours via membrane-inserted ligands for the CAR
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16. Octa-arginine-modified pegylated liposomal doxorubicin: An effective treatment strategy for non-small cell lung cancer
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17. Redox and pH Dual Responsive Polymer Based Nanoparticles for In Vivo Drug Delivery
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18. Multiplexed Optical Imaging of Tumor-Directed Nanoparticles: A Review of Imaging Systems and Approaches
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19. Exploration of the Natural Active Small-Molecule Drug-Loading Process and Highly Efficient Synergistic Antitumor Efficacy
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20. Safety Considerations of Cancer Nanomedicine—A Key Step toward Translation
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21. CD44‐Targeting Drug Delivery System of Exosomes Loading Forsythiaside A Combats Liver Fibrosis via Regulating NLRP3‐Mediated Pyroptosis
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22. A state-of-the-art review of the recent advances of theranostic liposome hybrid nanoparticles in cancer treatment and diagnosis
    Hannaneh Azimizonuzi, Arman Ghayourvahdat, Mareb Hamed Ahmed, Radhwan Abdul Kareem, Athmar Jaber Zrzor, Aseel Salah Mansoor, Zainab H. Athab, Shaylan Kalavi · 2025 · Cancer Cell International
23. Tumor-Targeted Paclitaxel Delivery and Enhanced Penetration Using TAT-Decorated Liposomes Comprising Redox-Responsive Poly(Ethylene Glycol)
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24. Immunotoxicity derived from manipulating leukocytes with lipid-based nanoparticles
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25. Exploring the relationship between anti-PEG IgM behaviors and PEGylated nanoparticles and its significance for accelerated blood clearance
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26. Cell-penetrating Peptide-based Intelligent Liposomal Systems for Enhanced Drug Delivery
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27. Drug-loaded titanium dioxide nanoparticle coated with tumor targeting polymer as a sonodynamic chemotherapeutic agent for anti-cancer therapy
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28. Poly(Sarcosine) Surface Modification Imparts Stealth‐Like Properties to Liposomes
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29. Anti-Epcam Aptamer (Syl3c)-Functionalized Liposome for Targeted Delivery Of Doxorubicin: In Vitro And In Vivo Antitumor Studies in Mice Bearing C26 Colon Carcinoma
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30. New approaches for targeting platinum-resistant ovarian cancer
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31. Review of Contemporary Self-Assembled Systems for the Controlled Delivery of Therapeutics in Medicine
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32. Current role of nanoparticles in the treatment of lung cancer
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33. Advanced Microfluidic Technologies for Lipid Nano-Microsystems from Synthesis to Biological Application
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34. Convergence of nanotechnology and artificial intelligence in the fight against liver cancer: a comprehensive review
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35. Remote‐Loaded Platelet Vesicles for Disease‐Targeted Delivery of Therapeutics
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36. Adipose‐Derived Biogenic Nanoparticles for Suppression of Inflammation
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37. Comparison of extracellular vesicle isolation processes for therapeutic applications
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38. Technological advances in the use of viral and non-viral vectors for delivering genetic and non-genetic cargos for cancer therapy
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39. Recent advances in access to overcome cancer drug resistance by nanocarrier drug delivery system
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40. Nanoparticle-mediated thermal Cancer therapies: Strategies to improve clinical translatability
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41. Inertial cavitation to non-invasively trigger and monitor intratumoral release of drug from intravenously delivered liposomes
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42. Recent advances in multifunctional silica-based hybrid nanocarriers for bioimaging and cancer therapy
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43. Development of Liposomal Gemcitabine with High Drug Loading Capacity
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44. Nanocarrier-mediated antioxidant delivery for liver diseases
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45. Preparation, characterization and in vitro anticancer performance of nanoconjugate based on carbon quantum dots and 5-Fluorouracil
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46. Doxorubicin nanoformulations on therapy against cancer: An overview from the last 10 years
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47. Lipid-based nanosystems: the next generation of cancer immune therapy
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48. Leveraging machine learning to streamline the development of liposomal drug delivery systems
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49. Aggregation Behavior of Polystyrene-Nanoparticles in Human Blood Serum and its Impact on the in vivo Distribution in Mice
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50. Microfluidic synthesis of multifunctional liposomes for tumour targeting
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51. Nanomedicines Against Chagas Disease: an Update on Therapeutics, Prophylaxis and Diagnosis
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52. Targeted Biomimetic Nanoparticles for Synergistic Combination Chemotherapy of Paclitaxel and Doxorubicin
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53. Dissociation of fluorescently labeled lipids from liposomes in biological environments challenges the interpretation of uptake studies
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54. Improvement in the Anti-Tumor Efficacy of Doxorubicin Nanosponges in In Vitro and in Mice Bearing Breast Tumor Models
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55. Nuclear imaging approaches facilitating nanomedicine translation
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56. Macropinocytosis as a cell entry route for peptide-functionalized and bystander nanoparticles
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57. Phytochemical-Loaded Liposomes for Anticancer Therapy: An Updated Review
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58. Nanomedicine‐Enabled/Augmented Cell Pyroptosis for Efficient Tumor Nanotherapy
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59. Lipid Nanoparticles Functionalized with Antibodies for Anticancer Drug Therapy
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60. Nanoparticles advanced from preclinical studies to clinical trials for lung cancer therapy
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61. Blood–Brain Barrier Conquest in Glioblastoma Nanomedicine: Strategies, Clinical Advances, and Emerging Challenges
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62. Nanotechnology-Based Drug Delivery Systems for Melanoma Antitumoral Therapy: A Review
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63. POZylation: a new approach to enhance nanoparticle diffusion through mucosal barriers
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64. Liposomal Bortezomib Nanoparticles via Boronic Ester Prodrug Formulation for Improved Therapeutic Efficacy in Vivo
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65. Significantly enhanced tumor cellular and lysosomal hydroxychloroquine delivery by smart liposomes for optimal autophagy inhibition and improved antitumor efficiency with liposomal doxorubicin
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66. Development of Injectable PEGylated Liposome Encapsulating Disulfiram for Colorectal Cancer Treatment
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67. Passive targeting in nanomedicine: fundamental concepts, body interactions, and clinical potential
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68. Tuning liposome composition to modulate corona formation in human serum and cellular uptake
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69. Fabrication of 3D-Printed Fish-Gelatin-Based Polymer Hydrogel Patches for Local Delivery of PEGylated Liposomal Doxorubicin
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70. Opportunities and challenges in commercial pharmaceutical liposome applications
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71. Regulatory Considerations Specific to Liposome Drug Development as Complex Drug Products
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72. Nanomaterial-encapsulated STING agonists for immune modulation in cancer therapy
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73. Innovative Delivery Systems for Curcumin: Exploring Nanosized and Conventional Formulations
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74. Precise nanoscale fabrication technologies, the “last mile” of medicinal development
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75. Cellular Delivery of Doxorubicin via pH-Controlled Hydrazone Linkage Using Multifunctional Nano Vehicle Based on Poly(β-L-Malic Acid)
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76. Review of ultrasound mediated drug delivery for cancer treatment: updates from pre-clinical studies
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77. Maßgeschneiderte Nanopartikel für den Wirkstofftransport in der Krebstherapie
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78. Dual pH/reduction-responsive hybrid polymeric micelles for targeted chemo-photothermal combination therapy
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79. Amphiphilic Drug Conjugates as Nanomedicines for Combined Cancer Therapy
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80. Recent Advances in Nano-Drug Delivery Systems for the Treatment of Diabetic Wound Healing
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81. Innovative Design of Targeted Nanoparticles: Polymer–Drug Conjugates for Enhanced Cancer Therapy
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82. The nasal delivery of nanoencapsulated statins – an approach for brain delivery
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83. Analyzing Liposomal Drug Delivery Systems in Three-Dimensional Cell Culture Models Using MALDI Imaging Mass Spectrometry
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84. Triggered Release from Lipid Bilayer Vesicles by an Artificial Transmembrane Signal Transduction System
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85. Bile acid transporter mediated endocytosis of oral bile acid conjugated nanocomplex
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86. Aggregation of polyethylene glycol polymers suppresses receptor-mediated endocytosis of PEGylated liposomes
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87. Chloroquine and nanoparticle drug delivery: A promising combination
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88. Practical aspects in size and morphology characterization of drug-loaded nano-liposomes
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89. Externally Triggered Heat and Drug Release from Magnetically Controlled Nanocarriers
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90. Biomedical applications of metal organic polygons and polyhedra (MOPs)
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91. Rapid scale-up and production of active-loaded PEGylated liposomes
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93. Leukocytes as carriers for targeted cancer drug delivery
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94. Hybrid Nanoplatforms Comprising Organic Nanocompartments Encapsulating Inorganic Nanoparticles for Enhanced Drug Delivery and Bioimaging Applications
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95. Near‐Infrared Light‐Absorptive Stealth Liposomes for Localized Photothermal Ablation of Tumors Combined with Chemotherapy
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96. Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer
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97. Pharmacokinetics and Pharmacodynamics Modeling and Simulation Systems to Support the Development and Regulation of Liposomal Drugs
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98. Toxicological profile of lipid-based nanostructures: are they considered as completely safe nanocarriers?
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99. The diffusion of doxorubicin drug molecules in silica nanoslits is non-Gaussian, intermittent and anticorrelated
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100. Nanoparticles as Theranostic Vehicles in Experimental and Clinical Applications—Focus on Prostate and Breast Cancer
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