Dopamine-loaded blood exosomes targeted to brain for better treatment of Parkinson’s disease

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Alvarez-Erviti, L., Seow, Y., Yin, H., Betts, C., Lakhal, S., & Wood, M. J. A. (2011) · Nature Biotechnology · doi:10.1038/nbt.1807 · Cited by 4,930

Regulated portals of entry into the cell

Conner, S. D., & Schmid, S. L. (2003) · Nature · doi:10.1038/nature01451 · Cited by 3,958

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Peinado, H., Alečković, M., Lavotshkin, S., Matei, I., Costa-Silva, B., Moreno-Bueno, G., Hergueta-Redondo, M., Williams, C., García-Santos, G., Ghajar, C. M., et al. (2012) · Nature Medicine · doi:10.1038/nm.2753 · Cited by 3,715

Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: Selective externalization of the receptor

Pan, B., & Johnstone, R. M. (1983) · Cell · doi:10.1016/0092-8674(83)90040-5 · Cited by 2,042

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

Tian, Y., Li, S., Song, J., Ji, T., Zhu, M., Anderson, G. J., Wei, J., & Nie, G. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.11.083 · Cited by 1,841

Molecular Pathways of Neurodegeneration in Parkinson's Disease

Dawson, T. M., & Dawson, V. L. (2003) · Science · doi:10.1126/science.1087753 · Cited by 1,674

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

Ohno, S.-I., Takanashi, M., Sudo, K., Ueda, S., Ishikawa, A., Matsuyama, N., Fujita, K., Mizutani, T., Ohgi, T., Ochiya, T., et al. (2013) · Molecular Therapy · doi:10.1038/mt.2012.180 · Cited by 1,666

A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

Sun, D., Zhuang, X., Xiang, X., Liu, Y., Zhang, S., Liu, C., Barnes, S., Grizzle, W. E., Miller, D., & Zhang, H. (2010) · Molecular Therapy · doi:10.1038/mt.2010.105 · Cited by 1,579

Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells

Kim, M. S., Haney, M. J., Zhao, Y., Mahajan, V., Deygen, I., Klyachko, N. L., Inskoe, E., Piroyan, A., Sokolsky, M., Okolie, O., et al. (2016) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2015.10.012 · Cited by 1,410

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

Zhuang, X., Xiang, X., Grizzle, W., Sun, D., Zhang, S., Axtell, R. C., Ju, S., Mu, J., Zhang, L., Steinman, L., et al. (2011) · Molecular Therapy · doi:10.1038/mt.2011.164 · Cited by 1,356

Emerging Potential of Exosomal Non-coding RNA in Parkinson’s Disease: A Review

Zhang, P., Rasheed, M., Liang, J., Wang, C., Feng, L. P., & Chen, Z. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.819836 · Cited by 19

Inflammation and JNK's Role in Niacin-GPR109A Diminished Flushed Effect in Microglial and Neuronal Cells With Relevance to Schizophrenia

Ansarey, S. H. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.771144 · Cited by 21

Potential for Therapeutic-Loaded Exosomes to Ameliorate the Pathogenic Effects of α-Synuclein in Parkinson’s Disease

Rademacher, D. J. (2023) · Biomedicines · doi:10.3390/biomedicines11041187 · Cited by 18

MicroRNA-23a-3p Is Upregulated in Plasma Exosomes of Bulbar-onset ALS Patients and Targets ERBB4

Liu, Y., Ding, M., Pan, S., Zhou, R., Yao, J., Fu, R., Yu, H., & Lu, Z. (2023) · Neuroscience · doi:10.1016/j.neuroscience.2023.05.030 · Cited by 18

Extracellular Vesicles in Malaria: Shedding Light on Pathogenic Depths

Dey, S., Mohapatra, S., Khokhar, M., Hassan, S., & Pandey, R. K. (2024) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.3c00649 · Cited by 21

Treating amyotrophic lateral sclerosis with allogeneic Schwann cell–derived exosomal vesicles: a case report

Goldschmidt‐Clermont, P. J., Khan, A., Jimsheleishvili, G., Graham, P., Brooks, A. E., Silvera, R., Goldschmidt, A. J. P., Pearse, D. D., Dietrich, W. D., Levi, A. D., et al. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-23-01815 · Cited by 18

Camouflaging nanoreactor traverse the blood-brain barrier to catalyze redox cascade for synergistic therapy of glioblastoma

Cheng, W., Ren, W., Ye, P., Li, H., Bao, D., Yue, T., Lai, J., Wu, Y., Wei, Y., Wu, Z., et al. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122702 · Cited by 19

Imaging platforms to dissect the in vivo communication, biodistribution and controlled release of extracellular vesicles

Banerjee, A., Lino, M. M., Jesus, C., Ribeiro, Q., Abrunhosa, A., & Ferreira, L. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.06.039 · Cited by 18

A comprehensive and updated review on the applications of vesicular drug delivery systems in treatment of brain disorders: A shelter against storms

Rajizadeh, M. A., Motamedy, S., Mir, Y., Akhgarandouz, F., Nematollahi, M. H., & Nezhadi, A. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.105011 · Cited by 17

Exosome surface modification and functionalization: a narrative review of emerging technologies and their application potential in precision medicine

Chao, T., Zhao, J., Gao, R., Wang, H., Guo, J., Gao, Z., & Wang, Y. (2025) · Advanced technology in neuroscience . · doi:10.4103/atn.atn-d-24-00025 · Cited by 21

Nanomedicine: a cost-effective and powerful platform for managing neurodegenerative diseases

Hassanzadeh-khanmiri, M., Moshari, A., Kheradmand, R., Haghgouei, T., Homaei, M., Charsouei, S., & Mobed, A. (2025) · Metabolic Brain Disease · doi:10.1007/s11011-025-01564-3 · Cited by 17

Exosomes: The endogenous nanomaterials packed with potential for diagnosis and treatment of neurologic disorders

Tang, X., He, Y., Liu, J., Xu, J., & Peng, Q. (2024) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2024.113938 · Cited by 17

Brain-targeted drug delivery assisted by physical techniques and its potential applications in traditional Chinese medicine

Sun, Y., Du, L., Yang, M., Li, Q., Jia, X., Li, Q., Zhu, L., Zhang, Y., Liu, Y., & Liu, S. (2021) · Journal of Traditional Chinese Medical Sciences · doi:10.1016/j.jtcms.2021.07.003 · Cited by 18

Mesenchymal Cell-Derived Exosomes as Novel Useful Candidates for Drug Delivery

Einabadi, M., Ai, J., Kargar, M., Kafilzadeh, F., Nooshabadi, V. T., & Jamali, H. (2020) · Archives of Neuroscience · doi:10.5812/ans.98722 · Cited by 16

Surface-functionalized nanoparticles for targeted drug delivery across the blood-brain barrier: advances and challenges in neurodegenerative disease therapy

Pramoda, G., Verma, R. K., Kesharwani, P., & Shukla, R. (2025) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2025.127938 · Cited by 15

The role of exosomes in diagnosis, pathophysiology, and management of Alzheimer's Disease

Daksh, R., Mathew, M. S., Bosco, A. M., Sojan, C., Tom, A. A., Bojja, S. L., & Nampoothiri, M. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.151526 · Cited by 16

Extracellular vesicle manufacture via FACTORY: fully automated collection technology and optimum machinery for clinical translational applications

Liu, X.-C., Tian, J.-W., Xu, J., Chen, L., Ye, Z., Huang, J., Wu, L., Zhang, Z., Yu, Z., & Chen, G. (2025) · Trends in biotechnology · doi:10.1016/j.tibtech.2025.06.020 · Cited by 16

Modern Strategies of Drug Therapy: Multi-Target Drug Delivery, Bioimaging, Diagnostics

Fedorova, O. V., Ovchinnikova, I. G., Rusinov, G. L., Avdeeva, V. V., Zhdanov, А. P., Zhizhin, K. Y., Kuznetsov, N. T., Zakharova, L. Y., Kuznetsova, D. A., Razuvayeva, Y. S., et al. (2025) · Russian Journal of General Chemistry · doi:10.1134/s1070363225606726 · Cited by 16

Deciphering the Role of Nanoparticle-based Treatment for Parkinson’s Disease

Moni, M. M. R., Begum, M. M., Uddin, M. S., & Ashraf, G. M. (2021) · Current Drug Metabolism · doi:10.2174/1389200222666210202110129 · Cited by 15

CircRTN4 aggravates mesangial cell dysfunction by activating the miR-513a-5p/FN axis in lupus nephritis

Miao, X., Tian, Y., Wu, L., Zhao, H., Liu, J., Gao, F., Zhang, W., Liu, Q., Guo, H., Yang, L., et al. (2022) · Laboratory Investigation · doi:10.1038/s41374-022-00788-6 · Cited by 15

Theoretical and applied concepts of nanocarriers for the treatment of Parkinson's diseases

Bhosale, A., Paul, G., Mazahir, F., & Yadav, A. K. (2022) · OpenNano · doi:10.1016/j.onano.2022.100111 · Cited by 15

Aβ1-42-containing platelet-derived extracellular vesicle is associated with cognitive decline in Parkinson’s disease

Wang, Z., Zheng, Y., Cai, H., Yang, C., Li, S., Lv, H., Feng, T., & Yu, Z. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1170663 · Cited by 16

Cell primitive-based biomimetic nanomaterials for Alzheimer's disease targeting and therapy

Yin, T., Liu, Y., He, B., Gong, B., Chu, J., Gao, C., Liang, W., Hao, M., Sun, W., Zhuang, J., et al. (2023) · Materials Today Bio · doi:10.1016/j.mtbio.2023.100789 · Cited by 16

Microglial exosomes in paraquat-induced Parkinson's disease: Neuroprotection and biomarker clues

Wu, J., Shao, W., Liu, X., Zheng, F., Wang, Y., Cai, P., Guo, Z., Hu, H., Yu, G., Guo, J., et al. (2024) · Environmental Pollution · doi:10.1016/j.envpol.2024.124035 · Cited by 16

Research progress on astrocyte-derived extracellular vesicles in the pathogenesis and treatment of neurodegenerative diseases

Zhu, Y., Wang, F., Xia, Y., Wang, L., Lin, H., Zhong, T., & Wang, X. (2024) · Reviews in the Neurosciences · doi:10.1515/revneuro-2024-0043 · Cited by 15

Unveiling the role of exosomes as cellular messengers in neurodegenerative diseases and their potential therapeutic implications

Ashique, S., Kumar, N., Mishra, N., Muthu, S., Rajendran, R. L., Chandrasekaran, B., Obeng, B. F., Hong, C. M., Krishnan, A., Ahn, B., et al. (2024) · Pathology - Research and Practice · doi:10.1016/j.prp.2024.155451 · Cited by 16

Intranasal delivery of mesenchymal stem cell-derived exosomes ameliorates experimental autoimmune encephalomyelitis

Wu, J., Li, A., Shi, Y., Wang, Y., Luo, J., Zhuang, W., Ma, X., Qiao, Z., Xiu, X., Lang, X., et al. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.113853 · Cited by 19

Biofunctionalized nanomaterials for Parkinson's disease theranostics: potential for efficient PD biomarker detection and effective therapy

Sabnam, S., Kumar, R., & Tiwari, P. (2025) · Biomaterials Science · doi:10.1039/d5bm00179j · Cited by 15

Upregulation of exosomal circPLK1 promotes the development of non-small cell lung cancer through the miR-1294/ high mobility group protein A1 axis

Li, C., Wang, G., Ma, X., Tao, T., Li, Q., Yang, Y., Sang, H., & Wang, Z. (2022) · Bioengineered · doi:10.1080/21655979.2022.2026727 · Cited by 15

Parkinson's Disease: Current Status, Diagnosis, and Treatment Using Nanomedicines

Hasan, I., Roy, S., Guo, B., & Chang, C. (2023) · Advanced Therapeutics · doi:10.1002/adtp.202300058 · Cited by 14

Nature vs. Manmade: Comparing Exosomes and Liposomes for Traumatic Brain Injury

Hennigan, K., & Lavik, E. (2023) · The AAPS Journal · doi:10.1208/s12248-023-00849-8 · Cited by 14

Beneficial Effects of Human Schwann Cell-Derived Exosomes in Mitigating Secondary Damage After Penetrating Ballistic-Like Brain Injury

Nishimura, K., Sanchez‐Molano, J., Kerr, N. A., Pressman, Y., Silvera, R., Khan, A., Gajavelli, S., Bramlett, H. M., & Dietrich, W. D. (2024) · Journal of Neurotrauma · doi:10.1089/neu.2023.0650 · Cited by 14

MicroRNA-specific targets for neuronal plasticity, neurotransmitters, neurotrophic factors, and gut microbes in the pathogenesis and therapeutics of depression

Chen, C.-Y., Wang, Y., Lei, L., & Zhang, Y. (2024) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2024.111186 · Cited by 14

Engineering extracellular vesicles for Alzheimer's disease: An emerging cell‐free approach for earlier diagnosis and treatment

Lazar, S. V., Mor, S., Wang, D., Goldbloom‐Helzner, L., Clark, K. C., Hao, D., Farmer, D. L., & Wang, A. (2021) · WIREs Mechanisms of Disease · doi:10.1002/wsbm.1541 · Cited by 14

Therapeutic potential of extracellular vesicles in neurodegenerative disorders

Roudi, S., Rädler, J., & Andaloussi, S. E. (2023) · Handbook of clinical neurology · doi:10.1016/b978-0-323-85555-6.00017-5 · Cited by 14

The biodistribution of placental and fetal extracellular vesicles during pregnancy following placentation

Kang, M., Blenkiron, C., & Chamley, L. W. (2023) · Clinical Science · doi:10.1042/cs20220301 · Cited by 14

Targeted Liposomal Co-Delivery Dopamine with 3-n-Butylphthalide for Effective Against Parkinson’s Disease in Mice Model

Liang, Y., Feng, L., Zheng, Y., Gao, Y., Shi, R., Zhang, Z., Ying, X., & Zeng, Y. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s483595 · Cited by 13

Stem Cell Transplantation for Parkinson’s Disease: Current Challenges and Perspectives

Zeng, X., & Qin, H. (2022) · Aging and Disease · doi:10.14336/ad.2022.0312 · Cited by 13

Extracellular vesicles‐based theranostics for neurodegenerative diseases

Zhao, H., Zhu, L., Wang, C., & Yang, Y. (2024) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1993 · Cited by 14

Membrane vesicles nanotheranostic systems: sources, engineering methods, and challenges

Nie, W., Wu, G., Zhong, H., & Xie, H. (2020) · Biomedical Materials · doi:10.1088/1748-605x/abd2c8 · Cited by 14

Exosomal TAR DNA binding protein 43 profile in canine model of amyotrophic lateral sclerosis: a preliminary study in developing blood-based biomarker for neurodegenerative diseases

Pfeiffer, P., Coates, J. R., Esqueda, Y. M., Kennedy, A., Getchell, K., McLenon, M., Kosa, E., & Aǵbaş, A. (2022) · Annals of Medicine · doi:10.1080/07853890.2022.2153162 · Cited by 13

Multifaceted roles of extracellular vesicles in the interplay of neuroinflammation and neurodegenerative diseases

Deng, Z., Chen, H., Chen, J., Du, Z., Zhou, W., & Yuan, Z. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2025.167960 · Cited by 14

Nanotherapeutic Strategies for Overcoming the Blood–Brain Barrier: Applications in Disease Modeling and Drug Delivery

Kirit, E., Gokce, C., Altun, B., & Yılmazer, A. (2025) · ACS Omega · doi:10.1021/acsomega.5c02206 · Cited by 13

Potential of exosomes for targeted therapy in neuroinfectious disease management: crossing the blood–brain barrier

Bukke, S. P. N., Yadav, S., Prajapati, S., Rani, S. S., Reddy, M. S., Thalluri, C., Chettupalli, A. K., Goruntla, N., Pradeepkumar, B., Eftekhari, Z., et al. (2025) · Tissue Barriers · doi:10.1080/21688370.2025.2607157 · Cited by 12

Exosomes and MicroRNAs in Biomedical Science

Mirzaei, H., Rahimian, N., Mirzaei, H. R., Nahand, J. S., & Hamblin, M. R. (2022) · Synthesis lectures on biomedical engineering · doi:10.2200/s01171ed1v01y202202bme062 · Cited by 27

Distinct targeting and uptake of platelet and red blood cell‐derived extracellular vesicles into immune cells

Ilvonen, P., Pusa, R., Härkönen, K., Laitinen, S., & Impola, U. (2024) · Journal of Extracellular Biology · doi:10.1002/jex2.130 · Cited by 12

Plant-derived extracellular vesicles as potential smart nano drug delivery systems for antioxidant vitamins C and E in Alzheimer's disease

Jiyah, A., Muhammad, S. A., Ibrahim, A., Bulama, I., Ibrahim, A., Abbas, A. Y., Imam, M. U., Saidu, Y., & Bilbis, L. S. (2024) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2024.105618 · Cited by 13

Role of miRNAs in neurovascular injury and repair

Sawant, H., Sun, B., Mcgrady, E., & Bihl, J. C. (2024) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x241254772 · Cited by 12

Macrophage-derived exosomes exacerbate postoperative cognitive dysfunction in mice through inflammation

Qin, J., Yuan, H., An, X., Liu, R., & Meng, B. (2024) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2024.578403 · Cited by 13

Evolving nanoformulation strategies for diagnosis and clinical interventions for Parkinson’s disease

Chawla, S., Kalyane, D., Tambe, V., Deb, P. K., Kalia, K., & Tekade, R. K. (2019) · Drug Discovery Today · doi:10.1016/j.drudis.2019.12.005 · Cited by 12

Bioengineering exosomes for treatment of organ ischemia-reperfusion injury

Toghiani, R., Abolmaali, S. S., Najafi, H., & Tamaddon, A. M. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120654 · Cited by 12

Prospects for the Use of Small Extracellular Vesicles as a Transport Vehicle through the Blood–Brain Barrier

Хаспеков, Л. Г., & Yakovlev, A. A. (2023) · Neurochemical Journal · doi:10.1134/s1819712423010087 · Cited by 12

Applications of Exosomes in Targeted Drug Delivery for the Treatment of Parkinson’s Disease: A Review of Recent Advances and Clinical Challenges

Kumar, B., Pandey, M., Fayaz, F., Izneid, T. A., Pottoo, F. H., Manchanda, S., Sharma, A., & Sahoo, P. K. (2020) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026620666201019112557 · Cited by 11

Exosomes in Alzheimer’s disease: From pathogenesis to therapeutics—A comprehensive review of diagnostic and drug delivery applications

Shahlaei, M., Afkhami, H., Ahmadieh-Yazdi, A., Mirmazloumi, S. H., Sahraei, S. S., Akbari, M., Yang, P., Manoochehri, H., Tanzadehpanah, H., Mahaki, H., et al. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118548 · Cited by 11

Unlocking mRNA-driven CRISPR-Cas9 gene therapy via optimizing mRNA and the delivery vectors

Wang, S., Xu, X., Viitala, T., Shu, Y., & Zhang, H. (2025) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2025.102737 · Cited by 14

The emerging role of exosomes in Schizophrenia

Dai, J., Zhang, M., He, Q., & Chen, R. (2023) · Psychiatry Research · doi:10.1016/j.psychres.2023.115394 · Cited by 11

Nintedanib-loaded exosomes from adipose-derived stem cells inhibit pulmonary fibrosis induced by bleomycin

Cai, L., Wang, J., Xue, Y., Yu, S., Wang, C., Zhang, L., Zhang, X., Cheng, L., Ruan, W., Dong, F., et al. (2024) · Pediatric Research · doi:10.1038/s41390-024-03024-7 · Cited by 11

Cerebral biomimetic nano-drug delivery systems: A frontier strategy for immunotherapy

Tian, H., Yao, J., Ba, Q., Meng, Y., Cui, Y., Quan, L., Gong, W., Wang, Y., Yang, Y., Yang, M., et al. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.10.058 · Cited by 12

Nanotechnology in Parkinson’s Disease: overcoming drug delivery challenges and enhancing therapeutic outcomes

Ali, I., Adil, M., Imran, M., Qureshi, S. A., Qureshi, S., Hasan, N., & Ahmad, F. J. (2025) · Drug Delivery and Translational Research · doi:10.1007/s13346-025-01799-8 · Cited by 11

Biology, Pathology, and Targeted Therapy of Exosomal Cargoes in Parkinson’s Disease: Advances and Challenges

Almasi, F., Abbasloo, F., Soltani, N., Dehbozorgi, M., Fard, A. M., Kiani, A., Ghasemzadeh, N., Mesgari, H., Hosseingholi, E. Z., Payandeh, Z., et al. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-04788-7 · Cited by 12

Brain-derived extracellular vesicles: A promising avenue for Parkinson’s disease pathogenesis, diagnosis, and treatment

Zhang, S., Li, J., Hu, X., Liu, H., Yu, Q., Kuang, G., Liu, L., Yu, D., Lin, Z., & Xiong, N. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-01262 · Cited by 14

Extracellular vesicles in regenerative medicine

Romano, M., Zendrini, A., Paolini, L., Busatto, S., Berardi, A. C., Bergese, P., & Radeghieri, A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-817838-6.00002-4 · Cited by 11

Transport Characteristics of Placenta-Derived Extracellular Vesicles and Their Relevance to Placenta-to-Maternal Tissue Communication

Inagaki, M., & Tachikawa, M. (2022) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.c22-00072 · Cited by 11

Dendrimers-Based Drug Delivery System: A Novel Approach in Addressing Parkinson’s Disease

Ordonio, M. B., Zaki, R. M., & Elkordy, A. (2022) · Future Pharmacology · doi:10.3390/futurepharmacol2040027 · Cited by 11

Exosomes transport trace amounts of (poly)phenols

Arola‐Arnal, A., Hazas, M. L. D. L., Iglesias‐Carres, L., Mantilla-Escalante, D. C., Suárez, M., Busto, R., Visioli, F., Bladé, C., & Dávalos, A. (2020) · Food & Function · doi:10.1039/d0fo01824d · Cited by 11

Engineered extracellular vesicles (EVs): Promising diagnostic/therapeutic tools for pediatric high-grade glioma

Lyu, Y., Guo, Y., Okeoma, C. M., Yan, Z., Hu, N., Li, Z., Zhou, S., Zhao, X., Li, J., & Wang, X. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114630 · Cited by 11

The Role of Extracellular Vesicles in Musculoskeletal Diseases

Fu, P., Luo, Y., Zheng, S., Ma, Z., Xiao, W., Li, H., & Li, Y. (2025) · Journal of Extracellular Vesicles · doi:10.1002/jev2.70205 · Cited by 13

Exercise-mediated circulating metabolites for brain health

Wang, M., Nasb, M., Wu, T., Jia, M., & So, K. (2024) · Advanced Exercise and Health Science · doi:10.1016/j.aehs.2024.11.001 · Cited by 11

Cell inspired delivery system equipped with natural membrane structures in applications for rescuing ischemic stroke

Zhu, A., Jiang, Y., Pan, L., Li, J., Huang, Y., Shi, M., Di, L., Wang, L., & Wang, R. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.11.013 · Cited by 10

Exploring Exosome-Based Approaches for Early Diagnosis and Treatment of Neurodegenerative Diseases

Varshney, V., Gabble, B. C., Bishoyi, A. K., Varma, P., Qahtan, S. A., Kashyap, A., Panigrahi, R., Nathiya, D., & Chauhan, A. S. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05026-w · Cited by 10

Perspective insights and application of exosomes as a novel tool against neurodegenerative disorders: An expository appraisal

Kadbhane, A., Patel, M., Srivastava, S., Singh, P. K., Madan, J., Singh, S. B., & Khatri, D. K. (2021) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2021.102526 · Cited by 10

Exploring the role of exosomes in rheumatoid arthritis

Singh, A., Behl, T., Sehgal, A., Singh, S., Sharma, N., Naqwi, M., Mavi, A. K., & Singh, R. (2022) · Inflammopharmacology · doi:10.1007/s10787-022-01100-0 · Cited by 10

An Update on Peripheral Blood Extracellular Vesicles as Biomarkers for Parkinson's Disease Diagnosis

Wang, K., Shen, J., & Xu, Y. C. (2022) · Neuroscience · doi:10.1016/j.neuroscience.2022.11.017 · Cited by 10

Exosomes: Biological Couriers with Transformative Messages

Yousef, M. H., & Abdelnaser, A. (2019) · Journal of Biomedicine · doi:10.7150/jbm.34611 · Cited by 10

Circulating Extracellular Vesicles Are Increased in Newly Diagnosed Celiac Disease Patients

Efthymakis, K., Bologna, G., Simeone, P., Pierdomenico, L., Catitti, G., Vespa, S., Milano, A., Bellis, D. D., Laterza, F., Pandolfi, A., et al. (2022) · Nutrients · doi:10.3390/nu15010071 · Cited by 9

Exosomes as biomarkers and therapeutic measures for ischemic stroke

Shi, Y., Wang, R., Wang, L., Liu, Q., Han, L., Duan, X., Zhang, Y., Shen, A.-Z., Peng, D., Chen, W., et al. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.175477 · Cited by 9

The Biology, Pathological Roles of Exosomes and Their Clinical Application in Parkinson’s Disease

Huang, J., Yuan, X., Chen, L., Hu, B., Wang, H., & Huang, W. (2023) · Neuroscience · doi:10.1016/j.neuroscience.2023.09.001 · Cited by 9

The potential of exosomal biomarkers: Revolutionizing Parkinson's disease: How do they influence pathogenesis, diagnosis, and therapeutic strategies?

Akbari‐Gharalari, N., Ghahremani‐Nasab, M., Naderi, R., Chodari, L., & Nezhadshahmohammad, F. (2024) · AIMS neuroscience · doi:10.3934/neuroscience.2024023 · Cited by 10

Brain-Derived Exosomes in Neurodevelopmental and Neuropsychiatric Disorders: Molecular Insights, Therapeutic Potential, and Translational Challenges

Nikanfar, M., Avci, Ç. B., Khalilnezhad, A., Shahriyari, E., & Nourazarian, A. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05247-z · Cited by 10

Exosomes as a Nanotheranostic Platform in Brain Diseases

Kudpaje, M., Joghee, S., & Kumar, R. M. R. (2025) · European Journal of Neuroscience · doi:10.1111/ejn.70215 · Cited by 10

Tailored Extracellular Vesicles: Novel Tool for Tissue Regeneration

Li, L., Wu, P., Qian, H., Xu, W., Shi, H., & Jiang, J. (2022) · Stem Cells International · doi:10.1155/2022/7695078 · Cited by 9

Drug target therapy and emerging clinical relevance of exosomes in meningeal tumors

Sharma, S., Rana, R., Prakash, P., & Ganguly, N. K. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-023-04715-1 · Cited by 10

Bioinspired Approaches for Central Nervous System Targeted Gene Delivery

Kumar, J., Karim, A., Sweety, U. H., Sarma, H., Nurunnabi, M., & Narayan, M. (2023) · ACS Applied Bio Materials · doi:10.1021/acsabm.3c00842 · Cited by 9

Perspective in Nuclear Theranostics Using Exosome for the Brain

Hwang, D. W. (2019) · Nuclear Medicine and Molecular Imaging · doi:10.1007/s13139-018-00567-6 · Cited by 9

Combating Dopaminergic Neurodegeneration in Parkinson’s Disease through Nanovesicle Technology

Roy, R., Paul, R. K., Bhattacharya, P., & Borah, A. (2023) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00070 · Cited by 10

Characterization of Potent ABCG2 Inhibitor Derived from Chromone: From the Mechanism of Inhibition to Human Extracellular Vesicles for Drug Delivery

Valdameri, G., Kita, D. H., Dutra, J. D. P., Gomes, D. L., Tonduru, A. K., Kronenberger, T., Gavinho, B., Rossi, I. V., de Carvalho, M. M., Pérès, B., et al. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15041259 · Cited by 8

A call for standardization for secretome and extracellular vesicles in osteoarthritis: results show disease-modifying potential, but protocols are too heterogeneous—a systematic review

D’Arrigo, D., Salerno, M., Marziani, L. D., Boffa, A., & Filardo, G. (2024) · Human Cell · doi:10.1007/s13577-024-01084-9 · Cited by 8

Spheroid-Exosome-Based Bioprinting Technology in Regenerative Medicine

Lee, H.-Y., & Lee, J. W. (2024) · Journal of Functional Biomaterials · doi:10.3390/jfb15110345 · Cited by 10

Bioengineered exosomes: Cellular membrane-camouflaged biomimetic nanocarriers for Parkinson's disease management

Afzal, M., Hameed, H., Paiva‐Santos, A. C., Saleem, M., Hameed, A., & Ahmad, S. M. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.177199 · Cited by 8

Exosome-based platforms for treatment of multiple sclerosis

Zonouz, A. M., Rahbardar, M. G., & Alibolandi, M. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111256 · Cited by 9

Biological and Bioinspired Vesicles for Wound Healing: Insights, Advances and Challenges

Zhao, Y., Zhang, T., Zhao, G., Lu, J., Zhang, X., Lai, Y., Chen, Z., Ding, X., & Tai, Z. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s522067 · Cited by 10

Extracellular vesicles as the drug delivery vehicle for gene-based therapy

Aquino, A. D., Rubinstein, A., Кудрявцев, И. В., Yakovlev, A. A., & Головкин, А. С. (2025) · Applied Physics Reviews · doi:10.1063/5.0255519 · Cited by 9

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Salim, M. W., Zhang, W., Collins‐Praino, L. E., Wang, Y., & Care, A. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.202504608 · Cited by 8

Exosomes and Hair Restoration

Gupta, A., Hall, D. C., Rapaport, J. A., & Paradise, C. R. (2023) · Advances in Cosmetic Surgery · doi:10.1016/j.yacs.2022.10.002 · Cited by 8

Therapeutic potential of extracellular vesicles in Parkinson’s disease

Teixeira, M. R., Alievi, A. L., da Costa, V. R., Pinto, J. R. D., & Araldi, R. P. (2023) · Exploration of neuroscience · doi:10.37349/en.2023.00016 · Cited by 8

Deregulation of exosomal miRNAs in rheumatoid arthritis patients

Hussain, M. Z., Haris, M. S., Rizwan, M., Ashraf, N. S., Arshad, M., & Mahjabeen, I. (2023) · PLoS ONE · doi:10.1371/journal.pone.0289301 · Cited by 9

Challenges and opportunities for cancer stem cell‐targeted immunotherapies include immune checkpoint inhibitor, cancer stem cell‐dendritic cell vaccine, chimeric antigen receptor immune cells, and modified exosomes

Alqarni, A., Jasim, S. A., Altalbawy, F. M. A., Kaur, H., Kaur, I., Rodriguez‐Benites, C., Deorari, M., Alwaily, E. R., Al‐Ani, A. M., & Redhee, A. H. (2024) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.23719 · Cited by 8

The Role of Exosomes in the Pathogenesis, Diagnosis, and Treatment of Parkinson's and Alzheimer's Diseases

Moradi, H. R., Abdollahinezhad, S., & Heydarian, S. (2024) · The Neuroscience Journal of Shefaye Khatam · doi:10.61186/shefa.12.2.87 · Cited by 8

Loading Ovalbumin into Mesenchymal Stem Cell-Derived Exosomes as a Nanoscale Carrier with Immunomodulatory Potential for Allergen-Specific Immunotherapy

Dehnavi, S., Khodadadi, A., Asadirad, A., & Ghadiri, A. (2023) · Reports of Biochemistry and Molecular Biology · doi:10.52547/rbmb.11.4.626 · Cited by 8

A vivid outline demonstrating the benefits of exosome-mediated drug delivery in CNS-associated disease environments

Ray, R., Chowdhury, S. G., & Karmakar, P. (2024) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2024.109906 · Cited by 8

Applications of Exosomes in Targeted Drug Delivery for the Treatment of Parkinson’s Disease: A Review of Recent Advances and Clinical Challenges

Kumar, B., Pandey, M., Fayaz, F., Izneid, T. A., Pottoo, F. H., Manchanda, S., Sharma, A., & Sahoo, P. K. (2020) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026620666201019112557 · Cited by 11

Potential Therapeutic Applications and Developments of Exosomes in Parkinson’s Disease

Luo, S., Du, L., & Cui, Y. (2020) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.0c00195 · Cited by 34

Exosomes: Cellular capsules for drug delivery in Parkinson’s disease

Samal, J., Demir, S., & Pandit, A. S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-323-50922-0.00006-7 · Cited by 4

Plant-derived exosomes as cell homogeneous nanoplatforms for brain biomacromolecules delivery ameliorate mitochondrial dysfunction against Parkinson’s disease

Xu, Y., Yan, G., Zhao, J., Ren, Y., Xiao, Q., Tan, M., & Peng, L. (2024) · Nano Today · doi:10.1016/j.nantod.2024.102438 · Cited by 80

Research progress on exosome-mediated vascular endothelial growth factor–nerve growth factor cotransplantation in the treatment of Parkinson’s disease

Yan, W., Meng, X., & Li, X. (2025) · Journal of Aging and Rehabilitation · doi:10.1097/jagr.0000000000000024