The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Local drug delivery systems in the management of periodontitis: A scientific review
Abstract
Periodontitis (PD) is a microbial disease of tooth supporting tissues that results in progressive destruction of surrounding soft and hard tissues with eventual tooth mobility and exfoliation. Perioceutics, which includes the delivery of therapeutic agents via systemic and local means as an adjunct to mechanical therapy has revolutionized the arena of periodontal therapy. Selection of a right antimicrobial agent with appropriate route of drug administration is the key to successful periodontal therapy. Irrigating systems, fibers, gels, strips, films, microparticles, nanoparticles and low dose antimicrobial agents are some of the local drug delivery systems (LDDS) available in the field, which aims to deliver antimicrobial agents to sub-gingival diseased sites with minimal or no side-effects on other body sites. The present review aims to summarize the current state-of-the-art technology on LDDS in periodontal therapy thus ensure that the practitioners are able to choose LDD agents which are custom made for a specific clinical condition.
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Cites
Periodontitis: from microbial immune subversion to systemic inflammation
Hajishengallis, G. (2015) · Nature Reviews Immunology · doi:10.1038/nri3785 · Cited by 3,046
Kassebaum, N. J., Smith, A. G. C., Bernabé, E., Fleming, T. D., Reynolds, A. E., Vos, T., Murray, C. J. L., Marcenes, W., Collaborators, G. 2. O. H., Abyu, G. Y., et al. (2017) · Journal of Dental Research · doi:10.1177/0022034517693566 · Cited by 1,981
Global Burden of Oral Conditions in 1990-2010: A Systematic Analysis
Marcenes, W., Kassebaum, N. J., Bernabé, E., Flaxman, A., Naghavi, M., Lopez, A., & Murray, C. J. L. (2013) · Journal of Dental Research · doi:10.1177/0022034513490168 · Cited by 1,495
Hydrogels in a historical perspective: From simple networks to smart materials
Buwalda, S. J., Boere, K. W. M., Dijkstra, P. J., Feijen, J., Vermonden, T., & Hennink, W. E. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.03.052 · Cited by 994
Periodontal Disease and Diabetes Mellitus: A Two‐Way Relationship
Grossi, S. G., & Genco, R. J. (1998) · Annals of Periodontology · doi:10.1902/annals.1998.3.1.51 · Cited by 842
Natural history of periodontitis: Disease progression and tooth loss over 40 years
Ramseier, C. A., Anerud, A., Dulac, M., Lulic, M., Cullinan, M. P., Seymour, G. J., Faddy, M. J., Bürgin, W., Schätzle, M., & Lang, N. P. (2017) · Journal of Clinical Periodontology · doi:10.1111/jcpe.12782 · Cited by 264
Cited by
Bai, B., Gu, C., Lu, X., Ge, X., Yang, J., Wang, C., Gu, Y., Deng, A., Guo, Y., Feng, X., et al. (2021) · Nano Research · doi:10.1007/s12274-021-3376-1 · Cited by 67
Song, Y. W., Nam, J., Kim, J., Lee, Y., Choi, J., Min, H. S., Yang, H., Cho, Y., Hwang, S., Son, J., et al. (2025) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2024.122976 · Cited by 33
Metadata
- Authors
- H.R., R., Dhamecha, D., Jagwani, S., Rao, M., Jadhav, K., Shaikh, S., Puzhankara, L., & Jalalpure, S.
- Venue
- Journal of Controlled Release
- Publisher
- Elsevier BV
- Published
- 2019-08
- Volume
- 307
- Pages
- 393-409
- ISSN
- 0168-3659 (ISSN-L)
- OpenAlex
- W2954886192
- Cited by
- 236
- References
- 6
- FWCI
- 20.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- H.R., R., Dhamecha, D., Jagwani, S., Rao, M., Jadhav, K., Shaikh, S., Puzhankara, L., & Jalalpure, S. (2019). Local drug delivery systems in the management of periodontitis: A scientific review. Journal of Controlled Release. https://doi.org/10.1016/j.jconrel.2019.06.038
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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