The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Chitosan-based nanoparticles: An overview of biomedical applications and its preparation
Abstract
Abstract Chitosan (CS) is one of the most successfully developed biodegradable polymers. Among the numerous polymers developed to formulate polymeric nanoparticles, CS has fascinated considerable attention due to its appealing properties: (i) biodegradability and biocompatibility, (ii) FDA approval for wound dressings as well as in dietary application, (iii) non-toxicity, (v) scope of sustained release, (vi) probability to modify surface properties and (vii) scope of target nanoparticles (NPs) to particular organs or cells. This review presents different preparation methods of chitosan nanoparticles (CSNPs) from the methodological and mechanistic point of view. The crosslinking agent including aldehyde, tripolyphosphate (TPP), genipin and other cross linkers and the physicochemical behaviour of CSNPs including drug loading, drug release, particles size, zeta-potential and stability are briefly discussed. This review also presents why CS has been chosen to design nanoparticles (NPs) as drug delivery systems in various pharmaceutical applications.
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Cites
Cancer nanotechnology: opportunities and challenges
Ferrari, M. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1566 · Cited by 4,558
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Freeze-drying of nanoparticles: Formulation, process and storage considerations
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PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination
Garinot, M., Fiévez, V., Pourcelle, V., Stoffelbach, F., des Rieux, A., Plapied, L., Theate, I., Freichels, H., Jérôme, C., Marchand-Brynaert, J., et al. (2007) · Journal of Controlled Release · doi:10.1016/j.jconrel.2007.04.021 · Cited by 331
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Cited by
Recent advances in heavy metal removal by chitosan based adsorbents
Upadhyay, U., Sreedhar, I., Singh, S. A., Patel, C. M., & Anitha, K. L. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.117000 · Cited by 532
Harugade, A., Sherje, A. P., & Pethe, A. (2023) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2023.105634 · Cited by 474
Seyam, S., Nordin, N. A., & Alfatama, M. (2020) · Pharmaceuticals · doi:10.3390/ph13100307 · Cited by 85
Yee Kuen, C., & Masarudin, M. J. (2022) · Molecules · doi:10.3390/molecules27020473 · Cited by 78
Metadata
- Authors
- Naskar, S., Sharma, S., & Kuotsu, K.
- Venue
- Journal of Drug Delivery Science and Technology
- Publisher
- Elsevier BV
- Published
- 2019-02
- Volume
- 49
- Pages
- 66-81
- ISSN
- 1773-2247 (ISSN-L)
- OpenAlex
- W2898849725
- Cited by
- 237
- References
- 8
- FWCI
- 8.61
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.