Conflict of Interest Reporting in Dentistry Randomized Controlled Trials: A Systematic Review
Abstract
Objectives Conflict of interest (COI) reporting in the medical field has been a concern for a number of years. As the impact of industry on medical research increases, the need for transparency in these relationships increases. In this present study we aim to assess current practices and associations for COI reporting in the field of dentistry.Study design We conducted a systematic review of conflict of interest reporting for randomized controlled trials (RCTs) in 6 journals of Dentistry published between Jan 2011 and Mar 2012. We extracted study characteristics in duplicate and used descriptive statistics and Chi-square tests to assess associations.Results Of 1755 studies across seven journals, we identified 66 eligible RCTs. Many included studies were conducted in Europe (39%), with an average sample size of 355. A total of 76% of studies mentioned the presence or absence of potential COI. No correlation between the direction of results and whether a COI was declared was found (p = 0.328), nor was there an association between funding source and whether COI was discussed (p = 0.120). The journal in which the article was published did however have a correlation as to whether COI was discussed (p ≤ 0.0001).Conclusions RCTs published in the field of dental research inconsistently report the presence or absence of a conflict of interest. Dental journals should standardize conflict of interest reporting to aid dental researchers in understanding when a conflict of interest exists, and to provide transparency to readers and patients alike.
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In dental research, concerns regarding conflicting interests and potential financial sponsorship, particularly from industry, have persisted for decades.
“In dental research, concerns regarding conflicting interests and potential financial sponsorship, particularly from industry, have persisted for decades [31].”
From Assessing transparency practices in dental randomized controlled trials (2024) · cites this paper as [31]
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“In dental research, concerns regarding conflicting interests and potential financial sponsorship, particularly from industry, have persisted for decades [31].”
BackgroundBachelet, V. C., Barrera-Riquelme, C., Dallaserra, M., Ibarra, Á. A., Saavedra, M. G., Tapia-Davegno, C., & Julio Villanueva, M. (2023) · International journal of interdisciplinary dentistry · doi:10.4067/s2452-55882023000100049 · Cited by 2 · see citing works
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Industry Sponsorship in Dentistry: An Ethics Scoping Review
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Petridis, X., Tzanetakis, G. N., Jakovljević, A., Jaćimović, J., Koletsi, D., Nagendrababu, V., Duncan, H. F., & Dummer, P. M. H. (2025) · Australian Endodontic Journal · doi:10.1111/aej.70047
- Authors
- Beyari, M. M., Hak, A., Li, C. S., & Lamfon, H. A.
- Affiliations
- Umm al-Qura University (SA)
- Corresponding author
- Beyari, Mohammed M.
- ORCID
- Lamfon, Hanadi A.
- Venue
- Journal of Evidence Based Dental Practice
- Publisher
- Elsevier BV
- Published
- 2014-12
- Volume
- 14
- Issue
- 4
- Pages
- 158-164
- ISSN
- 1532-3382 (ISSN-L)
- OpenAlex
- W2081347423
- Cited by
- 14
- References
- 9
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 3 · 2017: 1 · 2016: 1
- FWCI
- 0.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Evidence Based Dental Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmaceutical industry and healthcare
- Social Sciences › Safety Research › Academic integrity and plagiarism
- Social Sciences › Decision Sciences › Information Systems and Management › Academic Publishing and Open Access
- Keywords
- conflicts of interest, conflict of interest disclosure, dental research, randomized controlled trials, research transparency, industry funding
- MeSH terms
- Ethics, Dental, Humans, Periodicals as Topic, Research Support as Topic, Randomized Controlled Trials as Topic, Conflict of Interest, Dental Research, Ethics, Research
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