Intranasal drug delivery: An alternative to intravenous administration in selected emergency cases
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The intranasal delivery method has been suggested as a route to administer NAL quickly in a needle-free system.
“Recently, the intranasal delivery method has been suggested as a route to administer NAL quickly in a needle-free system (58).”
From Oxytocin under opioid antagonism leads to supralinear enhancement of social attention (2017) · cites this paper as [58]
The common dose used for NAL nasal spray in prehospital settings with heroin overdose is 2 mg.
“Today, the common dose used for NAL nasal spray in prehospital settings with heroin overdose is 2 mg (58, 62).”
From Oxytocin under opioid antagonism leads to supralinear enhancement of social attention (2017) · cites this paper as [58]
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Oxytocin under opioid antagonism leads to supralinear enhancement of social attention
Dal Monte, O., Piva, M., Anderson, K. M., Tringides, M., Holmes, A. J., & Chang, S. W. C. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1702725114 · Cited by 55 · see citing works
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Naloxone therapy in opioid overdose patients: Intranasal or intravenous? A randomized clinical trial
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- Authors
- Wolfe, T. R., & Bernstone, T.
- Affiliations
- University of Utah (US)
- Corresponding author
- Wolfe, Timothy R
- Venue
- Journal of Emergency Nursing
- Publisher
- Elsevier BV
- Published
- 2004-04
- Volume
- 30
- Issue
- 2
- Pages
- 141-147
- ISSN
- 0099-1767 (ISSN-L)
- OpenAlex
- W2100669687
- Cited by
- 67
- References
- 26
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 1 · 2023: 3 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 4 · 2016: 5 · 2015: 2 · 2014: 8 · 2013: 2 · 2012: 4
- FWCI
- 1.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Emergency Nursing (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Inhalation and Respiratory Drug Delivery
- Health Sciences › Medicine › Otorhinolaryngology › Sinusitis and nasal conditions
- Keywords
- intranasal drug delivery, transmucosal drug absorption, nasal mucosa, emergency nursing, first-pass metabolism avoidance, plasma drug concentration
- MeSH terms
- Absorption, Administration, Intranasal, Analgesics, Opioid, Anesthetics, Local, Benzodiazepines, Biological Availability, Epistaxis, Humans, Hypnotics and Sedatives, Intubation, Gastrointestinal, Lidocaine, Naloxone, Narcotic Antagonists, Opioid-Related Disorders, Nasal Mucosa, Oxymetazoline, Seizures, Nasal Decongestants, Procedural Sedation, Conscious Sedation, Emergency Nursing
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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