Nasal absorption of naloxone and buprenorphine in rats
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In rodents, absorption of NAL through the nasal route is equivalent to the i.v. and intraduodenal routes.
“Similarly, in rodents, the absorption of NAL through the nasal route has been found to be equivalent to the i.v. and intraduodenal routes (60).”
From Oxytocin under opioid antagonism leads to supralinear enhancement of social attention (2017) · cites this paper as [60]
Cites
Pharmacokinetics of Naloxone in Rats and in Man
Ngai, S. H., Berkowitz, B. A., Yang, J. C., Hempstead, J. L., & Spector, S. (1976) · Anesthesiology · doi:10.1097/00000542-197605000-00008 · Cited by 288 · see citing works
Bullingham, R. E. S., McQuay, H. J., Moore, A., & Bennett, M. R. D. (1980) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.1980.219 · Cited by 167 · see citing works
Nasal absorption of propranolol from different dosage forms by rats and dogs
HUSSAIN, A. A., Hirai, S., & Bawarshi, R. (1980) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600691215 · Cited by 145 · see citing works
Self-citationDISPOSITION OF NALOXONE-7,8-3H IN NORMAL AND NARCOTIC-DEPENDENT MEN
Fishman, J., Roffwarg, H. P., & HELLMAN, L. (1973) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)29707-5 · Cited by 144 · see citing works
Nasal absorption of propranolol in humans
HUSSAIN, A. A., Foster, T. S., Hirai, S., et al. (1980) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600691037 · Cited by 143 · see citing works
Self-citationThe systemic bioavailability of buprenorphine by various routes of administration
BREWSTER, D. W., Humphrey, M., & McLeavy, M. A. (1981) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1981.tb13848.x · Cited by 99 · see citing works
Nasal Absorption of Natural Contraceptive Steroids in Rats—Progesterone Absorption
Hussainx, A. A., Hirai, S., & Bawarshi, R. (1981) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600700435 · Cited by 74 · see citing works
Nasal Absorption of Propranolol in Rats
HUSSAIN, A. A., Hirai, S., & Bawarshi, R. (1979) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600680942 · Cited by 74 · see citing works
Self-citationThe radioimmunoassay of buprenorphine
Bartlett, A. J., Lloyd-Jones, J. G., Rance, M. J., Flockhart, I. R., Dockray, G. J., Bennett, M. R. D., & Moore, R. A. (1980) · European Journal of Clinical Pharmacology · doi:10.1007/bf00561392 · Cited by 51 · see citing works
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Intranasal naloxone delivery is an alternative to intravenous naloxone for opioid overdoses
Merlin, M. A., Saybolt, M., Kapitanyan, R., Alter, S. M., Jeges, J., Liu, J., Calabrese, S., Rynn, K. O., Perritt, R., & Pryor, P. W. (2010) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2008.12.009 · Cited by 75 · see citing works
A response to the opioid overdose epidemic: Naloxone nasal spray
Wermeling, D. P. (2013) · Drug Delivery and Translational Research · doi:10.1007/s13346-012-0092-0 · Cited by 70 · see citing works
Intranasal drug delivery: An alternative to intravenous administration in selected emergency cases
Wolfe, T. R., & Bernstone, T. (2004) · Journal of Emergency Nursing · doi:10.1016/j.jen.2004.01.006 · Cited by 67 · see citing works
Oxytocin under opioid antagonism leads to supralinear enhancement of social attention
Dal Monte, O., Piva, M., Anderson, K. M., Tringides, M., Holmes, A. J., & Chang, S. W. C. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1702725114 · Cited by 55 · see citing works
Intranasal naloxone for the treatment of suspected heroin overdose
Kerr, D., Dietze, P., & Kelly, A. (2008) · Addiction · doi:10.1111/j.1360-0443.2007.02097.x · Cited by 51 · see citing works
- Authors
- Hussain, A., Kimura, R., Chong-Heng, H., & Kashihara, T.
- Affiliations
- University of Kentucky (US)
- Corresponding author
- Hussain, Anwar
- ORCID
- Hussain, Anwar
- Venue
- International Journal of Pharmaceutics
- Publisher
- Elsevier BV
- Published
- 1984-09
- Volume
- 21
- Issue
- 2
- Pages
- 233-237
- ISSN
- 0378-5173 (ISSN-L)
- OpenAlex
- W1964852963
- Cited by
- 68
- References
- 9
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 2 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 4 · 2016: 2 · 2014: 1 · 2013: 1 · 2012: 3
- FWCI
- 4.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Pharmaceutics (publishedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Inhalation and Respiratory Drug Delivery
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
- Keywords
- intranasal drug delivery, naloxone, buprenorphine, nasal bioavailability, intraduodenal administration, intravenous administration, opioid analgesics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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