Anti-inflammatory and anti-nociceptive activity of the water decoction Desmodium gangeticum
Abstract
The water decoction of root and aerial parts of Desmodium gangeticum (Leguminosae) was examined for anti-inflammatory and anti-nociceptive activity in experimental animals. The root and aerial decoction in doses of 5, 10 and 20 mg /kg caused a dose-dependent inhibition of swelling caused by carrageenin equivalent to 14.58-51.02% protection and 14.43-38.67%, respectively, in cotton pellet granuloma. There was a significant increase in analgesio-meter-induced force equivalent to 6.56-67.66% protection and 22.18-73.83% protection in acetic acid-induced writhing. The result establishes the traditional use of water decoction of Desmodium gangeticum codified in Indian System of Medicine.
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Antioxidant, anti-inflammatory and AChE inhibitory activity of D. gangeticum has been reported.
“Antioxidant, anti-inflammatory and AChE inhibitory activity of D. gangeticum has also been reported [199,201,202].”
From Indian Medicinal Herbs and Formulations for Alzheimer’s Disease, from Traditional Knowledge to Scientific Assessment (2020) · cites this paper as [202]
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- Authors
- Rathi, A., Rao, C. V., Ravishankar, B., De, S., & Mehrotra, S.
- Affiliations
- National Botanical Research Institute (IN)
- Gujarat Ayurved University (IN)
- Corresponding author
- Rathi, Anshu
- Venue
- Journal of Ethnopharmacology
- Publisher
- Elsevier BV
- Published
- 2004-12
- Volume
- 95
- Issue
- 2-3
- Pages
- 259-263
- ISSN
- 0378-8741 (ISSN-L)
- OpenAlex
- W2073069088
- Cited by
- 55
- References
- 23
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 4 · 2023: 2 · 2022: 1 · 2021: 2 · 2020: 3 · 2019: 2 · 2018: 1 · 2015: 8 · 2014: 6 · 2013: 4 · 2012: 3
- FWCI
- 1.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Ethnopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Health Sciences › Medicine › Complementary and alternative medicine › Phytochemicals and Medicinal Plants
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Keywords
- Desmodium gangeticum, anti-inflammatory activity, antinociceptive activity, water decoction, carrageenan-induced paw edema, cotton pellet granuloma, acetic acid-induced writhing, analgesia, root and aerial parts, traditional medicine, Ayurveda
- MeSH terms
- Analgesics, Animals, Anti-Inflammatory Agents, Non-Steroidal, Edema, Female, Fabaceae, Male, Medicine, Ayurvedic, Pain Measurement, Plant Extracts, Water, Plant Roots, Plant Components, Aerial, Mice, Rats
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