Cited by 205Cholinesterase and Neurodegenerative DiseasesMedicinal Plants and NeuroprotectionMedicinal Plant Extracts Effects

Screening of plants used in Danish folk medicine to treat memory dysfunction for acetylcholinesterase inhibitory activity

Adsersen, Anne, Gauguin, Bente, Gudiksen, Lene, Jäger, Anna K.·2006·Journal of Ethnopharmacology

Abstract

Aqueous and methanolic extracts of 11 plants, used in Danish folk medicine for improvement of memory and cognition, and 3 Corydalis species were tested for acetylcholinesterase inhibitory activity using the Ellman colorimetric method. Significant inhibitory activity in dose-dependent manner was observed for extracts of Corydalis cava, Corydalis intermedia, Corydalis solida ssp. laxa and Corydalis solida ssp. slivenensis. Extracts of Ruta graveolens, Lavandula angustifolia, Rosmarinus officinalis, Petroselinum crispum and Mentha spicata exhibited moderate inhibition of the enzyme, defined as more than 15% at 0.1 mg/ml.

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Crossref · 10.1016/j.jep.2005.09.032

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28 of 28 references verified0 citation errors · 0 not checkable

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Authors
Adsersen, A., Gauguin, B., Gudiksen, L., & Jäger, A. K.
Corresponding author
Adsersen, Anne
Venue
Journal of Ethnopharmacology
Publisher
Elsevier BV
Published
2006-04
Volume
104
Issue
3
Pages
418-422
ISSN
0378-8741 (ISSN-L)
OpenAlex
W1967774489
Cited by
205
References
28
Citations by year
2025: 4 · 2024: 7 · 2023: 9 · 2022: 10 · 2021: 12 · 2020: 19 · 2019: 17 · 2018: 10 · 2017: 13 · 2016: 11 · 2015: 10 · 2014: 12 · 2013: 12 · 2012: 16
FWCI
2.76
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Ethnopharmacology (publishedVersion)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
Funders
Sundhed og Sygdom, Det Frie Forskningsråd
Topics
  • Health Sciences › Medicine › Pharmacology › Cholinesterase and Neurodegenerative Diseases
  • Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plants and Neuroprotection
  • Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plant Extracts Effects
Keywords
acetylcholinesterase inhibition, folk medicine, memory impairment, plant extracts, Corydalis, Corydalis cava, Corydalis solida, Ruta graveolens, Lavandula angustifolia, Rosmarinus officinalis, parsley, Mentha spicata, cognitive enhancement
MeSH terms
Acetylcholinesterase, Cholinesterase Inhibitors, Chromatography, Thin Layer, Denmark, Dose-Response Relationship, Drug, Medicine, Traditional, Memory Disorders, Plant Extracts, Plants, Medicinal, Nootropic Agents

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