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Efficacy and safety of adjuvant curcumin therapy in ulcerative colitis: A systematic review and meta-analysis
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“A recent systematic review and meta-analysis found that adjuvant curcumin use produced a significant beneficial effect on clinical remission of UC compared to placebo; however, no significant effects were identified regarding clinical improvement, endoscopic remission, or endoscopic improvement (Yin et al., 2022).”
From A systematic review of the efficacy and safety of turmeric in the treatment of digestive disorders (2024) · cites this paper as Yin et al., 2022
In the citing paper
“A recent systematic review and meta-analysis found that adjuvant curcumin use produced a significant beneficial effect on clinical remission of UC compared to placebo; however, no significant effects were identified regarding clinical improvement, endoscopic remission, or endoscopic improvement (Yin et al., 2022).”
From A systematic review of the efficacy and safety of turmeric in the treatment of digestive disorders (2024) · cites this paper as Yin et al., 2022
In the citing paper
“A recent systematic review by Yin et al. ignored clinical and methodological heterogeneity of seven studies investigating curcumin use in UC and included metaanalyses (Yin et al., 2022)”
From A systematic review of the efficacy and safety of turmeric in the treatment of digestive disorders (2024) · cites this paper as Yin et al., 2022
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“Earlier systematic reviews have also demonstrated limitations within the available evidence (Goulart et al., 2021;Grammatikopoulou et al., 2018;Yin et al., 2022).”
From A systematic review of the efficacy and safety of turmeric in the treatment of digestive disorders (2024) · cites this paper as Yin et al., 2022
In the citing paper
“statistical heterogeneity was high (I 2 = 80%-85%) across almost all outcomes”
From A systematic review of the efficacy and safety of turmeric in the treatment of digestive disorders (2024) · cites this paper as Yin et al., 2022
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Cumpston, M., Li, T., Page, M. J., Chandler, J., Welch, V. A., Higgins, J. P., & Thomas, J. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.ed000142 · Cited by 7,218
PRESS Peer Review of Electronic Search Strategies: 2015 Guideline Statement
McGowan, J., Sampson, M., Salzwedel, D. M., Cogo, E., Foerster, V., & Lefebvre, C. (2016) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2016.01.021 · Cited by 5,700
Rethlefsen, M. L., Kirtley, S., Waffenschmidt, S., Ayala, A. P., Moher, D., Page, M. J., Koffel, J. B., PRISMA-S Group, Blunt, H., Brigham, T., et al. (2021) · Systematic Reviews · doi:10.1186/s13643-020-01542-z · Cited by 3,714
Rethlefsen, M. L., Kirtley, S., Waffenschmidt, S., Ayala, A. P., Moher, D., Page, M. J., & Koffel, J. (2019) · doi:10.31219/osf.io/sfc38 · Cited by 3,696
The Essential Medicinal Chemistry of Curcumin
Nelson, K. M., Dahlin, J. L., Bisson, J., Graham, J., Pauli, G. F., & Walters, M. A. (2017) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6b00975 · Cited by 1,956
Magro, F., Gionchetti, P., Eliakim, R., Ardizzone, S., Armuzzi, A., Barreiro-de Acosta, M., Burisch, J., Gecse, K. B., Hart, A. L., Hindryckx, P., et al. (2017) · Journal of Crohn's and Colitis · doi:10.1093/ecco-jcc/jjx008 · Cited by 1,910
Research works printed but not linked: 69
- Alizadeh, 2018, Curcumin nanomicelle improves semen parameters, oxidative stress, inflammatory biomarkers, and reproductive hormones in infertile men: a randomized clinical trial, Phytother Res., 32, 514, 10.1002/ptr.5998 · DOI
- Amalraj, 2017, Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives - a review, J Tradit Complement Med, 7, 205, 10.1016/j.jtcme.2016.05.005 · DOI
- Amalraj, 2017, A novel highly bioavailable curcumin formulation improves symptoms and diagnostic indicators in rheumatoid arthritis patients: a randomized, double-blind, placebo-controlled, two-dose, three-arm, and parallel-group study, J. Med. Food, 20, 1022, 10.1089/jmf.2017.3930 · DOI
- Amin, 2015, Clinical efficacy of the co-administration of Turmeric and Black seeds (Kalongi) in metabolic syndrome - a double blind randomized controlled trial - TAK-MetS trial, Compl. Ther. Med., 23, 165, 10.1016/j.ctim.2015.01.008 · DOI
- Anand, 2007, Bioavailability of curcumin: problems and promises, Mol. Pharm., 4, 807, 10.1021/mp700113r · DOI · Paper page
- Asteriou, 2018, Curcumin for the management of periodontitis and early ACPA-positive rheumatoid arthritis: killing two birds with one stone, Nutrients, 10, 908, 10.3390/nu10070908 · DOI
- Bahramsoltani, 2017, Pharmacokinetic interactions of curcuminoids with conventional drugs: a review, J. Ethnopharmacol., 209, 1, 10.1016/j.jep.2017.07.022 · DOI
- Banerjee, 2021, Novel bioenhanced curcumin With mesalamine for induction of clinical and endoscopic remission in mild-to-moderate ulcerative colitis: a randomized double-blind placebo-controlled pilot study, J. Clin. Gastroenterol., 55, 702, 10.1097/MCG.0000000000001416 · DOI
- Baumgart, 2007, Inflammatory bowel disease: clinical aspects and established and evolving therapies, Lancet, 369, 1641, 10.1016/S0140-6736(07)60751-X · DOI · Paper page
- Bommelaer, 2020, Oral curcumin No more effective than placebo in preventing recurrence of crohn’s disease after surgery in a randomized controlled trial, Clin. Gastroenterol. Hepatol., 18, 1553, 10.1016/j.cgh.2019.08.041 · DOI
- Burge, 2019, Curcumin and intestinal inflammatory diseases: molecular mechanisms of protection, Int. J. Mol. Sci., 20, 1912, 10.3390/ijms20081912 · DOI
- Carbonnel, 2016, Methotrexate is not superior to placebo for inducing steroid-free remission, but induces steroid-free clinical remission in a larger proportion of patients with ulcerative colitis, Gastroenterology, 150, 380, 10.1053/j.gastro.2015.10.050 · DOI
- Fan, 2020, Curcumin, as a pleiotropic agent, improves doxorubicin-induced nephrotic syndrome in rats, J. Ethnopharmacol., 250, 112502, 10.1016/j.jep.2019.112502 · DOI
- Ghosh, 2015, The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: a recent update, Food Chem. Toxicol., 83, 111, 10.1016/j.fct.2015.05.022 · DOI
- Gopi, 2017, Comparative oral absorption of curcumin in a natural turmeric matrix with two other curcumin formulations: an open-label parallel-arm study, Phytother Res., 31, 1883, 10.1002/ptr.5931 · DOI
- Grammatikopoulou, 2018, Oral adjuvant curcumin therapy for attaining clinical remission in ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials, Nutrients, 10, 1737, 10.3390/nu10111737 · DOI · Paper page
- Gupta, 2013, Therapeutic roles of curcumin: lessons learned from clinical trials, AAPS J., 15, 195, 10.1208/s12248-012-9432-8 · DOI · Paper page
- Hanai, 2006, Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind, placebo-controlled trial, Clin. Gastroenterol. Hepatol., 4, 1502, 10.1016/j.cgh.2006.08.008 · DOI · Paper page
- Hanauer, 2004, Medical therapy for ulcerative colitis 2004, Gastroenterology, 126, 1582, 10.1053/j.gastro.2004.02.071 · DOI
- Hanauer, 2006, Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities, Inflamm. Bowel Dis., 12, S3, 10.1097/01.MIB.0000195385.19268.68 · DOI
- Hibi, 2006, Novel pathophysiological concepts of inflammatory bowel disease, J. Gastroenterol., 41, 10, 10.1007/s00535-005-1744-3 · DOI
- Higgins, 2003, Measuring inconsistency in meta-analyses, Bmj, 327, 557, 10.1136/bmj.327.7414.557 · DOI · Paper page
- Hussain, 2017, Nanoencapsulation, an efficient and promising approach to maximize wound healing efficacy of curcumin: a review of new trends and state-of-the-art, Colloids Surf. B Biointerfaces, 150, 223, 10.1016/j.colsurfb.2016.11.036 · DOI
- Ihara, 2017, TGF-β in inflammatory bowel disease: a key regulator of immune cells, epithelium, and the intestinal microbiota, J. Gastroenterol., 52, 777, 10.1007/s00535-017-1350-1 · DOI
- Iqbal, 2018, Use of curcumin in achieving clinical and endoscopic remission in ulcerative colitis: a systematic review and meta-analysis, Am. J. Med. Sci., 356, 350, 10.1016/j.amjms.2018.06.023 · DOI
- Jobin, 1999, Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity, J. Immunol., 163, 3474, 10.4049/jimmunol.163.6.3474 · DOI
- Kaiser, 1999, Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kappaB activation in mouse colonocytes, Gastroenterology, 116, 602, 10.1016/S0016-5085(99)70182-4 · DOI
- Kedia, 2017, Low dose oral curcumin is not effective in induction of remission in mild to moderate ulcerative colitis: results from a randomized double blind placebo controlled trial, World J. Gastrointest. Pharmacol. Therapeut, 8, 147, 10.4292/wjgpt.v8.i2.147 · DOI · Paper page
- Ko, 2019, AGA clinical practice guidelines on the management of mild-to-moderate ulcerative colitis, Gastroenterology, 156, 748, 10.1053/j.gastro.2018.12.009 · DOI · Paper page
- Kunnumakkara, 2017, Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases, Br. J. Pharmacol., 174, 1325, 10.1111/bph.13621 · DOI
- Lang, 2015, Curcumin add-on therapy for induction of remission in mild-moderate active Ulcerative Colitis: A multi-center, prospective, randomized, double-blind, placebo-controlled trial, J. Crohns Colitis, 9, S300
- Levine, 2017, Mesalamine enemas for induction of remission in oral mesalamine-refractory pediatric ulcerative colitis: a prospective cohort study, J Crohns Colitis, 11, 970, 10.1093/ecco-jcc/jjx042 · DOI
- Lang, 2015, Curcumin in combination With mesalamine induces remission in patients with mild-to-moderate ulcerative colitis in a randomized controlled trial, Clin. Gastroenterol. Hepatol., 13, 1444, 10.1016/j.cgh.2015.02.019 · DOI · Paper page
- Levine, 2002, A randomized, double blind, dose-response comparison of balsalazide (6.75 g), balsalazide (2.25 g), and mesalamine (2.4 g) in the treatment of active, mild-to-moderate ulcerative colitis, Am. J. Gastroenterol., 97, 1398
- Li, 2020, Curcumin metabolites contribute to the effect of curcumin on ameliorating insulin sensitivity in high-glucose-induced insulin-resistant HepG2 cells, J. Ethnopharmacol., 259, 113015, 10.1016/j.jep.2020.113015 · DOI
- Liu, 2015, Methodology guideline for clinical studies investigating traditional Chinese medicine and integrative medicine: executive summary, Compl. Ther. Med., 23, 751, 10.1016/j.ctim.2015.08.001 · DOI
- Liu, 2013, Curcumin ameliorates dextran sulfate sodium-induced experimental colitis by blocking STAT3 signaling pathway, Int. Immunopharm., 17, 314, 10.1016/j.intimp.2013.06.020 · DOI
- Marteau, 2005, Combined oral and enema treatment with Pentasa (mesalazine) is superior to oral therapy alone in patients with extensive mild/moderate active ulcerative colitis: a randomised, double blind, placebo controlled study, Gut, 54, 960, 10.1136/gut.2004.060103 · DOI
- Masoodi, 2018, The efficacy of curcuminoids in improvement of ulcerative colitis symptoms and patients' self-reported well-being: a randomized double-blind controlled trial, J. Cell. Biochem., 119, 9552, 10.1002/jcb.27273 · DOI · Paper page
- Midura-Kiela, 2012, Curcumin inhibits interferon-γ signaling in colonic epithelial cells, Am. J. Physiol. Gastrointest. Liver Physiol., 302, G85, 10.1152/ajpgi.00275.2011 · DOI
- Mirzaei, 2017, Phytosomal curcumin: a review of pharmacokinetic, experimental and clinical studies, Biomed. Pharmacother., 85, 102, 10.1016/j.biopha.2016.11.098 · DOI · Paper page
- Nakase, 2021, Evidence-based clinical practice guidelines for inflammatory bowel disease 2020, J. Gastroenterol., 56, 489, 10.1007/s00535-021-01784-1 · DOI
- Negi, 1999, Antibacterial activity of turmeric oil: a byproduct from curcumin manufacture, J. Agric. Food Chem., 47, 4297, 10.1021/jf990308d · DOI
- Neurath, 2014, Cytokines in inflammatory bowel disease, Nat. Rev. Immunol., 14, 329, 10.1038/nri3661 · DOI · Paper page
- Okuda, 2019, The additive effects of low dose intake of ferulic acid, phosphatidylserine and curcumin, not alone, improve cognitive function in APPswe/PS1dE9 transgenic mice, Biol. Pharm. Bull., 42, 1694, 10.1248/bpb.b19-00332 · DOI
- Panahi, 2017, Curcuminoids modify lipid profile in type 2 diabetes mellitus: a randomized controlled trial, Compl. Ther. Med., 33, 1, 10.1016/j.ctim.2017.05.006 · DOI
- Prasad, 2014, Curcumin, a component of golden spice: from bedside to bench and back, Biotechnol. Adv., 32, 1053, 10.1016/j.biotechadv.2014.04.004 · DOI
- Priyadarsini, 2014, The chemistry of curcumin: from extraction to therapeutic agent, Molecules, 19, 20091, 10.3390/molecules191220091 · DOI · Paper page
- Rahmani, 2016, Treatment of non-alcoholic fatty liver disease with curcumin: a randomized placebo-controlled trial, Phytother Res., 30, 1540, 10.1002/ptr.5659 · DOI
- Rogler, 1998, Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa, Gastroenterology, 115, 357, 10.1016/S0016-5085(98)70202-1 · DOI · Paper page
- Rubin, 2019, ACG clinical guideline: ulcerative colitis in adults, Am. J. Gastroenterol., 114, 384, 10.14309/ajg.0000000000000152 · DOI
- S W, 1859, Morbid appearances in the intestine of miss bankes, London Medical Gazette, 2, 264
- Sadeghi, 2020, The effect of curcumin supplementation on clinical outcomes and inflammatory markers in patients with ulcerative colitis, Phytother Res., 34, 1123, 10.1002/ptr.6581 · DOI · Paper page
- Sahebkar, 2016, Curcumin downregulates human tumor necrosis factor-α levels: a systematic review and meta-analysis ofrandomized controlled trials, Pharmacol. Res., 107, 234, 10.1016/j.phrs.2016.03.026 · DOI
- Salomon, 2017, An integrative curcumin-mesalamine therapy for remission induction in mild-moderate active ulcerative colitis: an international, multi-center, randomized, double-blind, placebo-controlled trial, BMC Compl. Alternative Med., 17
- Sandborn, 2010, Once-daily dosing of delayed-release oral mesalamine (400-mg tablet) is as effective as twice-daily dosing for maintenance of remission of ulcerative colitis, Gastroenterology, 138, 1286, 10.1053/j.gastro.2009.12.054 · DOI
- Schneider, 2015, Degradation of curcumin: from mechanism to biological implications, J. Agric. Food Chem., 63, 7606, 10.1021/acs.jafc.5b00244 · DOI
- Simadibrata, 2017, Efficacy of curcumin as adjuvant therapy to induce or maintain remission in ulcerative colitis patients: an evidence-based clinical review, Acta Med. Indones., 49, 363
- Singh, 2019, AGA technical review on the management of mild-to-moderate ulcerative colitis, Gastroenterology, 156, 769, 10.1053/j.gastro.2018.12.008 · DOI
- Singla, 2014, Induction with NCB-02 (curcumin) enema for mild-to-moderate distal ulcerative colitis - a randomized, placebo-controlled, pilot study, Journal of Crohn's & colitis, 8, 208, 10.1016/j.crohns.2013.08.006 · DOI
- Singla, 2014, Induction with NCB-02 (curcumin) enema for mild-to-moderate distal ulcerative colitis - a randomized, placebo-controlled, pilot study, J Crohns Colitis, 8, 208, 10.1016/j.crohns.2013.08.006 · DOI
- Sreedhar, 2016, Curcumin as a therapeutic agent in the chemoprevention of inflammatory bowel disease, Drug Discov. Today, 21, 843, 10.1016/j.drudis.2016.03.007 · DOI
- Ukil, 2003, Curcumin, the major component of food flavour turmeric, reduces mucosal injury in trinitrobenzene sulphonic acid-induced colitis, Br. J. Pharmacol., 139, 209, 10.1038/sj.bjp.0705241 · DOI
- Ungaro, 2017, Ulcerative colitis, Lancet, 389, 1756, 10.1016/S0140-6736(16)32126-2 · DOI
- Wang, 2018, Curcumin as a therapeutic agent for blocking NF-κB activation in ulcerative colitis, Immunopharmacol. Immunotoxicol., 40, 476, 10.1080/08923973.2018.1469145 · DOI
- Wei, 2021, Curcumin ameliorates DSS-induced colitis in mice by regulating the Treg/Th17 signaling pathway, Mol. Med. Rep., 23, 1, 10.3892/mmr.2020.11672 · DOI
- Wei, 2021, A combination index and glycoproteomics-based approach revealed synergistic anticancer effects of curcuminoids of turmeric against prostate cancer PC3 cells, J. Ethnopharmacol., 267, 113467, 10.1016/j.jep.2020.113467 · DOI
- Xu, 2004, Drug therapy for ulcerative colitis, World J. Gastroenterol., 10, 2311, 10.3748/wjg.v10.i16.2311 · DOI
- Yarlas, 2018, Health-related quality of life and work-related outcomes for patients with mild-to-moderate ulcerative colitis and remission status following short-term and long-term treatment with multimatrix mesalamine: a prospective, open-label study, Inflamm. Bowel Dis., 24, 450, 10.1093/ibd/izx041 · DOI
Cited by
A systematic review of the efficacy and safety of turmeric in the treatment of digestive disorders
Thavorn, K., Wolfe, D., Faust, L., Shorr, R., Akkawi, M., Isaranuwatchai, W., Klinger, C., Chai‐Adisaksopa, C., Tanvejsilp, P., Nochaiwong, S., et al. (2024) · Phytotherapy Research · doi:10.1002/ptr.8189 · Cited by 11
Metadata
- Authors
- Yin, J., Wei, L., Wang, N., Li, X., & Miao, M.
- Venue
- Journal of Ethnopharmacology
- Publisher
- Elsevier BV
- Published
- 2022-05
- Volume
- 289
- Pages
- 115041
- ISSN
- 0378-8741
- Cited by
- 45
- References
- 6
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Funders
- National Natural Science Foundation of China
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